cis-Diamminedichloroplatinum(II) given in low-dose continuous infusion with concurrent radiotherapy to patients affected by inoperable lung carcinoma: A pharmacokinetic approach

Journal of Cancer Research and Clinical Oncology

Volumn 124, Issue 1, 1998, Pages 37-43

  Morazzoni, Franca ^a   Canevali, Carmen ^a   Zucchetti, Massimo ^b   Caroli, Sergio ^c   Alimonti, Alessandro ^c   Petrucci, Francesco ^c   Giudice, Gabriella ^d   Masoni, Enrico ^a   Bedini, Amedeo Vittorio ^d  

^a UNIVERSITY OF MILAN   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Cisplatin pharmacokinetics; Lung Cancer; Prolonged continuous venous infusion; Radio chemotherapy treatment

Indexed keywords

CISPLATIN;

ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CANCER RADIOTHERAPY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG HALF LIFE; ESOPHAGITIS; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LEUKOPENIA; LUNG NON SMALL CELL CANCER; MALE; NAUSEA; PHARMACOKINETICS; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; SKIN TOXICITY; VOMITING;

ADULT; AGED; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CISPLATIN; COMBINED MODALITY THERAPY; FEMALE; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED;

EID: 0031884859     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004320050131     Document Type: Article

References (21)

1. Bedini AV, Tavecchio L, Milani F, Gramaglia A, Spreafico C, Marchianò A, Ravasi G (1991) Prolonged venous infusion of cisplatin and concurrent radiation therapy for lung carcinoma. Cancer 67:357-362
2. Bedini AV, Tavecchio L, Milani F, Gramaglia A, Spreafico C, Marchianò A, Ravasi G (1993) Non resectable stage IIIa-b lung carcinoma: a phase II study on continuous infusion of cisplatin and concurrent radiotherapy (plus adjuvant surgery). Lung Cancer 10:73-84
3. Bedini AV, Tavecchio L, Gramaglia A, Villa S, Milani F, Palazzi M, Ravasi G (1998) Non-resectable non-small-cell lung carcinoma: continuous infusion of cisplatin and concurrent radiotherapy plus adjuvant surgery. In: Rosenthal CJ, Rotman M (eds) Infusion chemotherapy - radiation interactions. Elsevier Science, Amsterdam, pp 261-268
4. Dewit L (1987) Combined treatment of radiation and cis-diamminedichloroplatinum(II): a review of experimental and clinical data. Int J Radiat Oncol Biol Phys 13:403-426
5. Dominici C, Petrucci F, Caroli S, Alimonti A, Clerico A, Castello M (1989) A pharmacokinetic study of high-dose continuous infusion cisplatin in children with solid tumors. J Clin Oncol 7:100-107
6. Ellerbroek NA, Fossella FV, Rich TA, Ajani JA, Komaki R, Roth JA, Holoye PJ (1991) Low dose continuous infusion cisplatin combined with external beam irradiation for advanced colorectal adenocarcinoma and unresectable non-small cell lung carcinoma. Int J Radiat Oncol Biol Phys 20:351-355
7. Groen HJM, Leest AHD van der, Vries EGE de, Uges DRA, Szabò BG, and Mulder NH (1995) Continuous carboplatin infusion during 6 weeks' radiotherapy in locally inoperable non small-cell lung cancer: a phase I and pharmacokinetic study. Bri J Cancer 72:992-997
8. Havemann K, Wolf M, Gorg C, Hackenbruch E, Pfab R, Gorg K (1992) Preclinical and clinical experience with cisplatin and carboplatin and simultaneous radiation in non-small cell lung cancer. Ann Oncol 3 [Suppl 3]:S33-S37
9. Miller AB, Hoogstraten B, Staquet M, Winkler RA (1981) Reporting results of cancer treatment. Cancer 47:207-214
10. Morazzoni F, Canevali C, Moschetti I, Todeschini R, Caroli S, Alimoti A, Petrucci F, Ravasi G, Bedini AV, Milani F, Palazzi M, Villa S, Giudice G (1995) Determination of platinum in plasma of patients affected by inoperable lung carcinoma treated with radiotherapy and concurrent low dose continuous infusion of cis-dichlorodiammine platinum(II). Cancer Chemother Pharmacol 35:529-532
11. Oken MM, Davis TE, Creech RH, Mc Fadden ET, Thormey DC, Carbone PP, Horton J (1982) Toxicity and response criteria of the Eastern Cooperative Oncology Group. Am J Clin Oncol 5:649-655
12. Powell MJD (1964) An efficient method for finding the minimum of a function of several variable without calculating derivatives. Comput J 7:155-162
13. Reece P, Stafford I, Russel J, Khan M, Gill PG (1987) Creatinine clearance as predictor of ultrafilterable platinum plasma levels and nephrotoxicity. J Clin Oncol 5:304-309
14. Sacchi Landriani G, Guardabasso V, Rocchetti M (1983) NL-FIT: a microcomputer program for non linear fitting. Comput Programs Biomed 16:35
15. Saunders MI, Bennet MH, Dische S, Anderson PJ (1984) Primary tumor control after radiotherapy for carcinoma of the bronchus. Int J Radiat Oncol Biol Phys 10:499-501
16. Schaake-Koning C, Van den Bogaert W, Dalesio O, Festen J, Hoogenhout J, Van Houtte P, Kirkpatrik A, Koolen M, Maat B, Nijs A, Renaud A, Rodrigus P, Schuster-Uitterhoeve L, Sculier JP, Van Zandwijk N, Bartelink H (1992) Effects of concomitant cisplatin and radiotherapy on inoperable non-small-cell lung cancer. N Engl J Med 326:524-530
17. Skov K, Mac Phail S (1991) Interaction of platinum drugs with clinically relevant X-ray doses in mammalian cells: a comparison of cisplatin, carboplatin, iproplatin, and tetraplatin. Int J Radiat Oncol Biol Phys 20:221-225
18. Soresi E, Clerici M, Grilli R, Borghini U, Zuccali R, Leoni M, Botturi M, Vergari C, Luporini G, Scoccia S (1988) A randomized clinical trial comparing radiation therapy and radiation therapy plus cis-dicholoammine platinum(II) in the treatment of locally advanced non-small cell lung cancer. Semin Oncol 6 [Suppl 7]:20-25
19. Trovò MG, Minatel E, Franchin G, Boccieri MG, Nascimben O, Bllzicco G, Pizzi G, Torretta A, Veronesi A, Gobitti C, Zanelli DJ, Monfardini S (1992) Radiotherapy versus radiotherapy enhanced by cisplatin in stage III non-small cell lung cancer. Int J Radiat Oncol Biol Phys 24:11-15
20. Van Harskamp G, Boven E, Vermoken JB, Van Deutekon H, Stam J, Njo KH, Karim AMBF, Tierie AH, Golding RP, Pinedo HM (1987) Phase II trial combined radiotherapy and daily low-dose cisplatin for inoperable locally advanced non-small cell lung cancer (NSCLC). Int J Radiat Oncol Biol Phys 13:1735-1738
21. Vokes EE, Ackland SP, Vogelzang NJ (1990) Cisplatin, carboplatin, and gallium nitrate. In: Lokich JJ (ed) Cancer chemotherapy by infusion (2nd edn). Precept, Chicago, pp 176-196