Regional haemodynamic differences between normotensive and spontaneously hypertensive rats - A microsphere study

Physiological Research

Volumn 47, Issue 1, 1998, Pages 9-15

  Granstam, S O ^a   Granstam, E ^a   Fellstrom B ^a   Lind, L ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Haemodynamics; Hypertension; Microsphere method; Regional blood flow; SHR rats

Indexed keywords

MICROSPHERE CE 141;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN REGION; CONTROLLED STUDY; HEART INDEX; HEART RATE; HEMODYNAMICS; MALE; NONHUMAN; ORGAN BLOOD FLOW; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; STRAIN DIFFERENCE; VASCULAR RESISTANCE;

ANIMALS; HEMODYNAMIC PROCESSES; HYPERTENSION; MALE; MICROSPHERES; RATS; RATS, INBRED SHR; RATS, INBRED WKY; REFERENCE VALUES; REGIONAL BLOOD FLOW; VASCULAR RESISTANCE;

EID: 0031884402     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. ALBRECHT I.: The hemodynamics of early stages of spontaneous hypertension in rats. Part 1: male study. Jpn. Circ. J. 38: 985-990, 1974.
2. FOLKOW B.: Physiological aspects of primary hypertension. Physiol. Rev. 62: 347-504, 1982.
3. HILLERDAL M.: Cochlear blood flow in rats measured by the microsphere method: evaluation of the method and some practical applications. Acta Univ. Uppsal. 80: 1-38, 1987.
4. JUDY W.V., FARRELL S.K.: Arterial baroreceptor reflex control of sympathetic nerve activity in the spontaneously hypertensive rat. Hypertension 1: 605-614, 1979.
5. KAWABE K., WATANABE T.X., SHIONO K., SOKABE H.: Influence on blood pressure of renal isografts between spontaneously hypertensive and normotensive rats, utilizing the F1 hybrids. Jpn Heart J. 20: 886-894, 1979.
6. KIMURA S., FUJIOKA S., FUKUI K., TAMAKI T., IWAO H., ABE Y.: Effects of an antihypertensive vasodilator, pinacidil, on regional blood flow in conscious spontaneously hypertensive rats. J. Pharmacobio-Dyn. 11: 430-437, 1988.
7. KONDO J., YAMADA Y., OKUMURA K., HASHIMOTO H., ITO T, SATAKE T.: 1,2-Diacylglycerol content in myocardium from spontaneously hypertensive rats during the development of hypertension. Basic Res. Cardiol. 85: 453-460, 1990.
8. KOSKINEN L.-O.D.: Cerebral and peripheral blood flow effects of TRH in the rat - a role of vagal nerves. Peptides 10: 933-938.
9. LUNDGREN Y.: Adaptive changes of cardiovascular design in spontaneous and renal hypertension. Acta Physiol. Scand. Suppl. 91: 1-62, 1974.
10. MORTON J.J., BEATTIE E.C., GRIFFIN S.A., MACPHERSON F., LYALL F., RUSSO D.: Vascular hypertrophy, renin and blood pressure in the young spontaneously hypertensive rat. Clin. Sci. 79: 523-530, 1990.
11. NATSUME T., GALLO A.J., PEGRAM B.L., FROHLICH E.D.: Hemodynamic effects of prolonged treatment with diltiazem in conscious normotensive and spontaneously hypertensive rats. Clin. Exp. Hypertens. A7: 1471-1479, 1985.
12. NISHIYAMA K., NISHIYAMA A., FROHLICH E.D.: Regional blood flow in normotensive and spontaneously hypertensive rats. Am. J. Physiol. 230: 691-698, 1976.
13. PFEFFER J.M., PFEFFER M.A., FISHBEIN C., FROHLICH E.D.: Cardiac function and morphology with aging in the spontaneously hypertensive rat. Am. J. Physiol. 237: H461-H468, 1979.
14. REED B.V., TUMA R.F.: The effects of nifedipine on regional vascular resistance and blood flow in the spontaneously hypertensive rat. Clin. Exp. Hypertens. A8: 963-979, 1986.
15. RETTIG R., STAUSS H., FOLBERTH C., GANTEN D., WALDHERR R., UNGER T.: Hypertension transmitted by kidneys from stroke-prone spontaneously hypertensive rats. Am. J. Physiol. 257: F197-F203, 1989.
16. RETTIG R., SCHMITT B.: Experimental hypertension following kidney transplantation in the rat. In: Handbook of Hypertension. Vol 16, Experimental and Genetic Models of Hypertension. W.H. BIRKENHÄGER, J.L. REID (eds), Elsevier, Amsterdam, 1994, pp. 141-157.
17. SMITH T.L., HUTCHINS P.M.: Central hemodynamics in the developmental stage of spontaneous hypertension in the unanesthetized rat. Hypertension 1: 508-517, 1979.
18. THOMAS G.R., WALDER C.E., THIEMERMANN C., VANE J.R.: Regional vascular resistance and hemodynamics in the spontaneously hypertensive rat: the effects of bradykinin. J. Cardiovasc. Pharmacol. 15: 211-217, 1990
19. TUMA R.F., VASTHARE U.S., IRION G.L., WIEDEMAN M.P.: Considerations in use of microspheres for flow measurements in anesthetized rat. Am. J. Physiol. 250: H137-H143, 1986.
20. YAMORI Y.: Pathogenesis of spontaneous hypertension as a model for essential hypertension. Jpn. Circ. J. 41: 259-265, 1977.
21. YAMORI Y.: Physiopathology of the various strains of spontaneously hypertensive rats. In: Hypertension. J. GENEST (ed), McGraw-Hill, Montreal, 1983, pp. 556-581.
22. YAMORI Y.: Development of the spontaneously hypertensive rat (SHR), the stroke-prone SHR (SHRSP) and their various substrain models for hypertension-related cardiovascular diseases. In: Handbook of Hypertension. Vol 16, Experimental and Genetic Models of Hypertension. W.H. BIRKENHÄGER, J.L. REID (eds), Elsevier, Amsterdam, 1994, pp. 346-364.