Breathing of awake goats during prolonged dysfunction of caudal M ventrolateral medullary neurons

Journal of Applied Physiology

Volumn 84, Issue 1, 1998, Pages 129-140

  Forster, H V ^a   Pan, L G ^b   Lowry, T F ^b   Feroah, T ^b   Gershan, W M ^b   Whaley, A A ^b   Forster, M M ^b   Sprtel, B ^b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b NONE

Author keywords

Excitatory amino acid receptors; Regulation of breathing; Ventrolateral medulla

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CARBON DIOXIDE; EXCITATORY AMINO ACID RECEPTOR; KAINIC ACID; KYNURENIC ACID; N METHYL DEXTRO ASPARTIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CHEMORECEPTOR; GOAT; LUNG GAS EXCHANGE; MEDULLA OBLONGATA; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RESPIRATION CONTROL; WAKEFULNESS;

EID: 0031884302     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1998.84.1.129     Document Type: Article

References (39)

1. Abrahams, T. P., P. J. Hornby, D. P. Walton, A. M. Taveira Da Silva, and R. A. Gillis. An excitatory amino acid(s) in the ventrolateral medulla is (are) required for breathing to occur in the anesthetized cat. J. Pharmacol. Exp. Ther. 259: 1388-1395, 1991.
2. Akilesh, M. R., M. Kamper, A. Li, and E. E. Nattie. Effects of unilateral lesions of retrotrapezoid nucleus on breathing in awake rats. J. Appl. Physiol. 82: 469-479, 1997.
3. Bernard, D. G., L. Aihua, and E. E. Nattie. Evidence for central chemoreception in the midline raphé. J. Appl. Physiol. 80: 108-115, 1996.
4. Bianchi, A. L., M. Denavit-Saubie, and S. Champagnat. Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters. Physiol. Rev. 75: 1-45, 1995.
5. Bongianni, F., M. Corda, G. A. Fontana, and T. Pantaleo. Excitatory and depressant respiratory responses to chemical stimulation of the rostral ventrolateral medulla in the cat. Acta Physiol. Scand. 148: 315-325, 1993.
6. Budzinska, K., C. von Euler, F. F. Kao, T. Pantaleo, and Y. Yamamoto. Effects of graded focal cold block in rostral areas of the medulla. Acta Physiol. Scand. 124: 329-340, 1985.
7. Cherniack, N. S., C. von Euler, I. Homma, and F. F. Kao. Graded changes in central chemoreceptor input by local temperature changes on the ventral surface of medulla. J. Physiol. (Lond.) 287: 191-211, 1979.
8. Coates, E. L., A. Li, and E. E. Nattie. Widespread sites of brain stem ventilatory chemoreceptors. J. Appl. Physiol. 75: 5-14, 1993.
9. Davis, J. D., R. H. Evans, A. A. Francis, and J. C. Watkins. 2-Amino-5-phosphonovalerate (2-APV), a potent and selective antagonist of amino acid-induced and synaptic excitation. Neurosci. Lett. 21: 77-81, 1981.
10. Dillon, G. H., D. E. Welsh, and T. G. Waldrop. Modulation of respiratory reflexes by an excitatory amino acid mechanism in the ventrolateral medulla. Respir. Physiol. 85: 55-72, 1991.
11. Dormer, K. J., and T. G. Bedford. Cardiovascular control by the rostral ventrolateral medulla in the conscious dog. Prog. Brain Res. 81: 265-277, 1989.
12. Forster, H. V., P. J. Ohtake, L. G. Pan, and T. F. Lowry. Effect on breathing of surface ventrolateral medullary cooling in awake, anesthetized and asleep goats. Respir. Physiol. In press.
13. Forster, H. V., P. J. Ohtake, L. G. Pan, T. F. Lowry, M. J. Korducki, E. A. Aaron, and A. L. Forster. Effects on breathing of ventrolateral medullary cooling in awake goats. J. Appl. Physiol. 78: 258-265, 1995.
14. Gatti, P. J., A. M. T. Da Silva, P. Hamosh, and R. A. Gillis. Cardiorespiratory effects produced by application of L-glutamic and kainic acid to the ventral surface of the cat hindbrain. Brain Res. 330: 21-29, 1985.
15. Gayoso, M. J., C. Primo, A. Al-Majdalawi, J. M. Fernandez, M. Garrosa, and C. Iniguez. Brain lesions and water-maze learning deficits after systemic administration of kainic acid to adult rats. Brain Res. 653: 92-100, 1994.
16. 2. J. Appl. Physiol. 72: 439-446, 1992.
17. Jung, R., E. N. Bruce, and P. G. Katona. Cardiorespiratory responses to glutamatergic antagonists in the caudal ventrolateral medulla of rats. Brain Res. 564: 286-295, 1991.
18. Lawing, W. L., D. E. Millhorn, D. A. Baylis, J. B. Dean, and A. Trzebski. Excitatory and inhibitory effects on respiration of L-glutamate microinjected superficially into the ventral aspects of the medulla oblongata in cats. Brain Res. 435: 322-326, 1987.
19. 2 in the cerebral ventricles on respiration. Role of ventrolateral medulla in regulation of respiratory and cardiovascular systems. Am. J. Physiol. 176: 39-44, 1954.
20. Loeschcke, H. H., J. DeLattre, M. E. Schlaefke, and C. O. Trouth. Effects on respiration and circulation of electrically stimulating the ventral surface of the medulla oblongata. Respir. Physiol. 10: 184-197, 1970.
21. Martin, R. L., and J. D. Sinclair. Kainic acid on the rat ventral medullary surface depresses hypoxic and hypercapnic ventilatory responses. Respir. Physiol. 80: 55-70, 1990.
22. McAllen, R. M. Location of neurones with cardiovascular and respiratory function, at the ventral surface of the cat's medulla. Neuroscience 18: 43-49, 1986.
23. McCrimmon, D. R., G. S. Mitchell, and M. S. Dekin. Glutamate, GABA, and serotonin in ventilatory control. In: Regulation of Breathing (2nd ed.), edited by J. A. Dempsey and A. I. Pack. New York: Dekker, 1995, chapt. 4, p. 71-150 (Lung Biol. Health Dis. Ser.)
24. McGeer, P. L., E. G. McGeer, and T. Hattori. Kainic acid as a tool in neurobiology. In: Kainic Acid as a Tool in Neurobiology, edited by E. G. McGeer, J. W. Olney, and P. L. McGeer. New York: Raven, 1978, chapt. 6, p. 123-138.
25. Mitchell, R. A., H. H. Loeschcke, J. W. Severinghaus, B. W. Richardson, and W. H. Massion. Regions of respiratory chemosensitivity on the surface of the medulla. Ann. NY Acad. Sci. 109: 661-681, 1963.
26. Mitra, J., N. R. Prabhakar, J. L. Overholt, and N. S. Cherniack. Respiratory effects of N-methyl-D-aspartate on the ventrolateral medullary surface. J. Appl. Physiol. 67: 1814-1819, 1989.
27. 2-sensitive phrenic and sympathetic output. J. Appl. Physiol. 74: 2958-2968, 1993.
28. Nattie, E. E., and A. Li. Fluorescence location of RVLM kainate microinjections that alter the control of breathing. J. Appl. Physiol. 68: 1157-1166, 1990.
29. 2 sensitivity in rats. Respir. Physiol. 97: 63-78, 1994.
30. Nattie, E. E., and A. Li. Rat retrotrapezoid nucleus iono- and metabotropic glutamate receptors and the control of breathing. J. Appl. Physiol. 78: 153-163, 1995.
31. Nattie, E. E., A. Li, and W. M. St. John. Lesions in retrotrapezoid nucleus decrease ventilatory output in anesthetized or decerebrate cats. J. Appl. Physiol. 71: 1364-1375, 1991.
32. 2 sensitivity. J. Appl. Physiol. 65: 1525-1534, 1988.
33. Ohtake, P. J., H. V. Forster, L. G. Pan, T. F. Lowry, M. J. Korducki, E. A. Aaron, and E. M. Weiss. Differential ventilatory responses to cooling the ventrolateral medullary surface of awake and adult goats. J. Appl. Physiol. 78: 247-257, 1995.
34. Ohtake, P. J., H. V. Forster, L. G. Pan, T. F. Lowry, M. J. Korducki, K. Smith, and A. L. Forster. Effect on breathing of neuronal dysfunction in the caudal ventral medulla of goats. J. Appl. Physiol. 79: 1586-1594, 1995.
35. Schlaefke, M. E., J. F. Kille, and H. H. Loescke. Elimination of central chemosensitivity by coagulation of a bilateral area on the ventral medullary surface in awake cats. Pflügers Arch. 378: 231-241, 1979.
36. Schwob, J. E., T. Fuller, J. L. Price, and J. W. Olney. Widespread patterns of neuronal damage following systemic or intracerebral injections of kainic acid: a histological study. Neuroscience 5: 991-1014, 1980.
37. Sheardown, M. J., E. O. Nielsen, A. J. Hansen, P. Jacobsen, and T. Honore. 2,3-Dihydroxy-6-nitro-7-sulfamozl-benzo (F) quinoxaline: a neuroprotectant for cerebral ischemia. Science 247: 571-574, 1990.
38. Smith, J. C., D. E. Morrison, H. H. Ellenberger, M. R. Otto, and J. L. Feldman. Brainstem projections to the major respiratory neuron populations in the medulla of the cat. J. Comp. Neurol. 281: 69-96, 1989.
39. Stone, T. W., and J. W. Connick. Quinolinic acid and other kynurenines in the central nervous system. Neuroscience 15: 597-618, 1985.