Is maternal serum triple screening a better predictor of Down syndrome in female than in male fetuses?

Prenatal Diagnosis

Volumn 18, Issue 2, 1998, Pages 123-126

  Ghidini, Alessandro ^a   Spong, Cathy Y ^b   Grier, Robert E ^b   Walker, Charles N ^b   Pezzullo, John C ^b  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^b NONE

Author keywords

Fetal gender; Prenatal diagnosis; Trisomy 21

Indexed keywords

ALPHA FETOPROTEIN; CHORIONIC GONADOTROPIN;

ADULT; AMNIOCENTESIS; ARTICLE; BLOOD LEVEL; DATA BASE; DOWN SYNDROME; FEMALE; FETUS; HUMAN; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; SEX DIFFERENCE; STATISTICAL ANALYSIS; TRISOMY 21;

ALPHA-FETOPROTEINS; AMNIOCENTESIS; CHORIONIC GONADOTROPIN; DOWN SYNDROME; ESTRIOL; FEMALE; HUMANS; KARYOTYPING; MALE; PREGNANCY; PRENATAL DIAGNOSIS; SEX CHARACTERISTICS;

MARTES PENNANTI;

EID: 0031884128     PISSN: 01973851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0223(199802)18:2<123::AID-PD221>3.0.CO;2-6     Document Type: Article

References (9)

1. Calvas, P., Bourrouillou, G., Smilovici, W., Colombies, P. (1990). Maternal serum alpha-fetoprotein and fetal sex, Prenat. Diagn., 10, 134-136 (Letter).
2. Leporrier, N., Herrol, M., Leymarie, P. (1992). Shift of the fetal sex ratios in hCG selected pregnancies at risk for Down syndrome, Prenat. Diagn., 12, 703-704.
3. Lockwood, C.J., Lynch, L., Ghidini, A., Lapinski, R., Berkowitz, G., Thayer, B., Miller, W.A. (1993). The effect of fetal gender on the prediction of Down syndrome by means of maternal serum a-fetoprotein and ultrasonographic parameters, Am. J. Obstet. Gynecol., 169, 1190-1197.
4. Mutton, D., Alberman, E., Hook, E.B. (1996). Cytogenetic and epidemiological findings in Down syndrome, England and Wales, 1989 to 1993, J. Med. Genet., 33, 387-394.
5. Petrikovsky, B. (1989). Maternal serum alpha fetoprotein concentration and fetal sex, Prenat. Diagn., 9, 449-450.
6. Sowers, S., Reisch, R.L., Burton, B.K. (1983). Fetal sex-related differences in maternal serum alpha-fetoprotein during the second trimester of pregnancy, Am. J. Obstet. Gynecol., 146, 786-789.
7. Szabó, M., Veress, L., Münnich, Á., Papp, Z. (1995). Maternal age-dependent and sex-related changes of gestational serum alpha-fetoprotein, Fetal Diagn. Ther., 10, 368-372.
8. Ulizzi, L., Zonta, L.A. (1995). Factors affecting the sex ratio in humans: multivariate analysis of the Italian population, Hum. Biol., 67, 59-67.
9. Wald, N.J., Cuckle, S. (1984). Open neural tube defects. In: Wald, N.J. (Ed.). Antenatal and Neonatal Screening, Oxford: Oxford University Press, 25.