The activities of acidic and glutamine-rich transcriptional activation domains in plant cells: Design of modular transcription factors for high-level expression

Plant Molecular Biology

Volumn 36, Issue 2, 1998, Pages 195-204

  Schwechheimer, Claus ^a   Smith, Caroline ^a   Bevan, Michael W ^a  

^a JOHN INNES CENTRE   (United Kingdom)

Author keywords

Activation domain; Transcription; Transcription factors; Transient transformation

Indexed keywords

FUNGAL PROTEIN; GAL VP16; GAL-VP16; HYBRID PROTEIN; RECOMBINANT PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; BINDING SITE; BIOSYNTHESIS; CELL CULTURE; CHEMISTRY; CONSENSUS SEQUENCE; CYTOLOGY; ESCHERICHIA COLI; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; METABOLISM; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PLANT; PLANT LEAF; PROMOTER REGION; PROTOPLAST; TOBACCO; TRANSACTIVATION;

BASE SEQUENCE; BINDING SITES; CELLS, CULTURED; CLONING, MOLECULAR; CONSENSUS SEQUENCE; ESCHERICHIA COLI; FUNGAL PROTEINS; PLANT LEAVES; PLANTS, TOXIC; PROMOTER REGIONS (GENETICS); PROTOPLASTS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; TOBACCO; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EMBRYOPHYTA; ESCHERICHIA COLI; HERPES; LYCOPERSICON ESCULENTUM; NICOTIANA TABACUM; SIMPLEXVIRUS;

EID: 0031884087     PISSN: 01674412     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005990321918     Document Type: Article

References (40)

1. Abrams E, Neigeborn L, Carlson M: Molecular analysis of SNF2 and SNF5, genes required for expression of glucose-repressible genes in Saccharomyces cerevisiae. Mol Cell Biol 6: 3643-651 (1986).
2. Berger SL, Cress WD, Cress A, Triezenberg SJ, Guarente L: Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: evidence for transcriptional adaptors. Cell 61: 1199-1208 (1990).
3. Brent R, Ptashne M: A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor. Cell 43: 729-736 (1985).
4. Carey M, Kakidani H, Leatherwood J, Mostashari F, Ptashne M: An amino-terminal fragment of GAL4 binds DNA as a dimer. J Mol Biol 209: 423-432 (1989).
5. Carey M, Lin Y-S, Green MR, Ptashne M: A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. Nature 345: 361-364 (1990).
6. Chevray PM, Nathans D: Protein interaction cloning in yeast: Identification of mammalian proteins that react with the leucine zipper of Jun. Proc Natl Acad Sci USA 89: 5789-5793 (1992).
7. Emami KH, Carey M: A synergistic increase in potency of a multimerised VP16 transcriptional activation domain. EMBO J 11: 5005-5012 (1992).
8. Fang RX, Nagy F, Sivasubramaniam S, Chua N-H: Multiple cis regulatory elements for maximal expression of the cauliflower mosaic virus 35S promoter in transgenic plants. Plant Cell 1: 141-150 (1989).
9. Gerber HP, Seipel K, Georgiev O, Hofferer M, Hug M, Rusconi S, Schaffner W: Transcriptional activation modulated by homopolymeric glutamine and proline stretches. Science 263: 808-811 (1994).
10. Gill G, Ptashne M: Negative effect of the transcriptional activator GAL4. Nature 334: 721-724 (1988).
11. Giniger E, Varnum SM, Ptashne M: Specific DNA binding of GAL4, a positive regulatory protein of yeast. Cell 40: 767-774 (1985).
12. Goodrich JA, Cutler G, Tjian R: Contacts in context: promoter specificity and macromolecular interactions in transcription. Cell 84: 825-830 (1996).
13. Goodrich JA, Hoey T, Thut CJ, Admon A, Tjian R: Drosophila TAFII40 interacts with both a VP16 domain and the basal transcription factor TFIIB. Cell 75: 519-530 (1993).
14. Guerineau F, Mullineaux P: Plant transformation and expression vectors. In: Croy RDD (ed) Plant Molecular Biology Lab-fax, pp. 125-127. BIOS Scientific Publishers, London (1993).
15. Hahn S: Structure and function of acidic transcription activators. Cell 72: 481-483 (1993).
16. Hoey T, Weinzierl ROJ, Gill G, Chen J-L, Dynlacht BD, Tjian R: Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected for coactivators. Cell 72: 247-260 (1993).
17. Jefferson RA: Assaying chimeric genes in plants: the GUS gene fusion system. Plant Mol Biol Rep 5: 387-405 (1987).
18. Lin Q, Hamilton WDO, Merryweather A: Cloning and initial characterization of 14 mye-related cDNAs from tomato (Lycopersicon esculentum cv. Ailsa Craig). Plant Mol Biol 30: 1009-1020 (1996).
19. Lin Y-S, Carey M, Ptashne M, Green MR: How different eukaryotic transcriptional activators can cooperate promiscuously. Nature 345: 359-361 (1990).
20. Lin Y-S, Ha I, Maldonado E, Reinberg D, Green MR: Binding of general transcription factor TFIIB to an acidic activating region. Nature 353: 569-571 (1991).
21. Luehrsen KR, de Wet JR, Walbot V: Transient expression analysis in plants using firefly luciferase reporter gene. Meth Enzymol 216: 397-414 (1992).
22. Ma J, Przibilla E, Hu J, Bogorad L, Ptashne M: Yeast activators stimulate plant gene expression. Nature 334: 631-633 (1988).
23. McCarty D, Hattori T, Carson CB, Vasil V, Lazar M, Vasil IK: The Viviparous-1 developmental gene of maize encodes a novel transcriptional activator. Cell 66: 895-905 (1991).
24. McKnight SL: Transcription revisited: a commentary on the 1995 Cold Spring Harbor Meeting, 'Mechanisms of Eukaryotic Transcription'. Genes Devel 10: 367-381 (1996).
25. Negrutiu I, Shillito R, Potrykus I, Biasini G, Sala F: Hybrid genes in the analysis of transformation conditions. Plant Mol Biol 8: 363-373 (1987).
26. Ohashi Y, Brickman JM, Furman E, Middleton B, Carey M: Modulating the potency of an activator in a yeast in vitro transcription system. Mol Cell Biol 14: 2731-2739 (1994).
27. Omirulleh S, Abraham M, Golovkin M, Karabaev MK, Mustardy L, Morocz S, Dudits D: Activity of a chimeric promoter with the doubled CaMV 35S enhancer element in protoplastderived cells and transgenic plants in maize. Plant Mol Biol 21: 415-428 (1993).
28. Ponticelli AS, Pardee TS, Struhl K: The glutamine-rich activation domains of human Sp1 do not stimulate transcription in Saccharomyces cerevisiae. Mol Cell Biol 15: 983-988 (1995).
29. Ranish JA, Hahn S: Transcription: basal factors and activation. Curr Opin Genet Devel 6: 151-158 (1996).
30. Roberts SGE, Green MR: Transcription: dichotomous regulators. Nature 375: 105-106 (1995).
31. Sambrook J, Fritsch EF, Maniatis T: Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (1989).
32. Sauer F, Wasserman DA, Rubin GM, Tjian R: TAFIIs mediate activation of transcription in the Drosophila embryo. Cell 87: 1271-1284 (1996).
33. Shufflebottom D: Ph.D. thesis, University of Cambridge (1992).
34. Töpfer R, Matzeit V, Gronenborn B, Schell J, Steinbiss H-H: A set of plant expression vectors for transcriptional and translational fusions. Nucl Acids Res 15: 5890 (1987).
35. Triezenberg SJ, Kingsbury RC, McKnight SL: Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression. Genes Devel 2: 718-729 (1988).
36. Ueda T, Waverczak W, Ward K, Sher N, Ketudat M, Schmidt RJ, Messing J: Mutations of the 22-kD and 27-kD zein promoters affect transactivation by the Opaque-2 protein. Plant Cell 4: 701-709 (1992).
37. Wilde RJ, Cooke SE, Brammar WJ, Schuch W: Control of gene expression in plant cells using a 434:VP16 chimeric protein. Plant Mol Biol 24: 381-388 (1994).
38. Wolffe AP and Pruss D: Targeting chromatin disruption: transcription regulators that acetylate histones. Cell 6: 817-819 (1994).
39. Workman JL, Taylor ICA, Kingston RE: Activation domains of stably bound GAL4 derivatives alleviate repression of promoters by nucleosomes. Cell 64: 533-544 (1991).
40. Xiao H, Pearson A, Coulombe B, Truant R, Zhang S, Regier JL, Triezenberg SJ, Reinberg D, Flores O, Ingles CJ, Greenblatt J: Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53. Mol Cell Biol 14: 7013-7024 (1994).