In vitro antiproliferative effect of halogenic quarternary ammonium on tumor cells;EFFET D'AMMONIUM QUATERNAIRE HALOGENE SUR DES CULTURES DE CELLULES TUMORALES

Comptes Rendus de l'Academie des Sciences - Serie III

Volumn 321, Issue 1, 1998, Pages 5-10

  Gastaud, Jean Marie ^a   Senelar, René ^a   Pujol, Henri ^a  

^a Anticancer Center   (France)

Author keywords

Halogenic quaternary ammonium; Phosphatidylcholine; Proliferative cancer cells

Indexed keywords

QUATERNARY AMMONIUM DERIVATIVE; GMS 041 F; GMS-041 F; TETRAZOLIUM;

ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GROWTH INHIBITION; HUMAN; HUMAN CELL; TUMOR CELL; CELL CULTURE; CELL DIVISION; CELL SURVIVAL; COLORIMETRY; DRUG EFFECT; DRUG SCREENING; HEALTH CARE ORGANIZATION; STATISTICAL MODEL; UNITED STATES;

CELL DIVISION; CELL SURVIVAL; COLORIMETRY; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; LOGISTIC MODELS; NATIONAL INSTITUTES OF HEALTH (U.S.); QUATERNARY AMMONIUM COMPOUNDS; TETRAZOLIUM SALTS; TUMOR CELLS, CULTURED; UNITED STATES;

EID: 0031884047     PISSN: 07644469     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0764-4469(97)89619-9     Document Type: Article

References (8)

1. [1] Billah M.M., Anthes J.C. 1990. The regulation of cellular funtions of phosphatidylcholin hydrolysis. Biochem. J. 269, 281-291.
2. [2] Thompson N.T., Bonser R.W., Garland L.G. 1991. Receptor-coupled phospholipase C and its inhibition. Trends Pharm. Sci. 12, 404-407
3. [3] Geilen C.C., Haase R., Buchner K., Wieder I., Mucho F., Reutter W. 1991. The phospholipid analogue, hexadecylphosphocholine, nhibits protein kinase C in vitro and antagonises phorbol esterstimulated cell proliferation. Eur. J. Cancer 27, 1650-1653.
4. [4] Mamorimoto H., Braquet C., Principe P., Mencis-Huerta J.M., Braquet P., Bonavida B. 1991. Cytotoxic activity of synthetic aza alkyl lysophospholipids against drug sensitive and drug resistant tumor cell lines. Anticancer Res. 11, 2223-2229.
5. [5] Zeisig R., Fichtner I., Arndt D., Jungman S. 1991. Antitumor effects of alkylphosphocholines in different murine tumor models: use of liposomal preparation. Anticancer Drug 2, 411-417.
6. [6] Gastaud J.-M. NCI 693172-H/I
7. [7] Skehan P., Storeng R., Scudiero D. et al. 1990. New colorimetric cytotoxicity assay for anticancer drug screening. J. Nat. Cancer Inst. 82, 1107-12.
8. [8] Heintz R., Bali J.P., Sénelar R., Gastaud J.M. 1993. Effet sur la prolifération de cellules tumorales gastriques de sels d'ammonium quarternaires chlorurométhylés. C. R. Acad. Sci. Paris 316, 1363-67.