Cleavage of GPI-anchored proteins from the plasma membrane activates apical endocytosis in pancreatic acinar cells

European Journal of Cell Biology

Volumn 75, Issue 2, 1998, Pages 163-173

  Freedman, Steven D ^a,d   Kern, Horst F ^b   Scheele, George A ^c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c Alpha Industries Inc   (United States)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Apical membrane trafficking; Exocrine pancreatic secretion; Exocytosis endocytosis; GPI linked proteins; Regulated apical endocytosis

Indexed keywords

DIACYLGLYCEROL; GLYCOSYLPHOSPHATIDYLINOSITOL; MEMBRANE PROTEIN; PHORBOL ESTER; PHOSPHOLIPASE C; PHOSPHOLIPID;

ACINAR CELL; ANIMAL CELL; ARTICLE; CELL MEMBRANE TRANSPORT; CELL PH; CONTROLLED STUDY; ENDOCYTOSIS; GEL ELECTROPHORESIS; IMMUNOBLOTTING; MALE; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT;

ANIMALIA; ARMORACIA RUSTICANA;

EID: 0031883674     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0171-9335(98)80058-7     Document Type: Article

References (28)

1. Alvarez, J. G., J. C. Touchstone: Separation of acidic and neutral lipids by amino-propyl bonded silica gel column chromatography. J. Chromatogr. 577, 142-145 (1992).
2. Alvarez, J. G., B. Slomovic, J. Ludmir: Analysis of dipalmitoyl phosphotidylcholine in amniotic fluid by enzymatic hydrolysis and high-performance thin-layer chromatography (HPTLC) - reflectance spectrodensitometry. J. Chromatogr. 665, 79-87 (1995).
3. Alvarez, J. G., B. T. Storey: Differential incorporation of fatty acids into and peroxidative loss of fatty acids from phospholipids of human spermatozoa. Mol. Reprod. Dev. 42, 334-346 (1995).
4. Berridge, M. J.: Inositol trisphosphate and calcium signalling. Nature 361, 315-325 (1993).
5. Brown, D. A., B. Crise, J. K.Rose: Mechanism of membrane anchoring affects polarized expression of two proteins in MDCK cells. Science 245, 1499-1501 (1989).
6. Cockcroft, S., G. M.Thomas: Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors. Biochem. J. 288, (Pt 1) 1-14 (1992).
7. Cosson, P. J. de Curtis, J. Pouyssegur, G. Griffiths, J. Davoust: Low cytoplasmic pH inhibits endocytosis and transport from the transGolgi network to the cell surface. J. Cell Biol. 108, 377-387 (1989).
8. Davoust, J., J. Gruenberg, K. E. Howell: Two threshold values of low pH block endocytosis at different stages. EMBO J. 6, 3601-3609 (1987).
9. Dawra, R. K., A. K. Saluja, M. Rimzi, M. L. Steer: Inositol trisphosphate-independent agonist-stimulated calcium influx in rat pancreatic acinar cells. J. Biol. Chem. 268, 20237-20242 (1993).
10. De Camilli, P., D. Peluchett, J. Meldolesi: Dynamic changes of the luminal plasmalemma in stimulated parotid acinar cells. A freeze fracture study. J. Cell Biol. 70, 59-74 (1976).
11. Ferguson, M., A. Williams: Cell-surface anchoring of proteins via glycosyl-phosphatidylinositol structures. Annu. Rev. Biochem. 57, 285-320 (1988).
12. Freedman, S. D., G. A. Scheele: Reversible pH-induced homophilic binding of GP2, a glycosyl-phosphatidylinositol-anchored protein in pancreatic zymogen granule membranes. Eur. J. Cell Biol. 61, 229-238 (1993).
13. Freedman, S. D., H. F. Kern, G. A. Scheele: Apical membrane trafficking during regulated pancreatic exocrine secretion - Role of alkaline pH in the acinar lumen and enzymatic cleavage of GP2, a GPI-linked protein. Eur. J. Cell Biol. 65, 354-365 (1994).
14. Freedman, S. D., H. F. Kern, G. A. Scheele: Acinar lumen pH regulates endocytosis, but not exocytosis, at the apical plasma membrane of pancreatic acinar cells. Eur. J. Cell Biol. 75, 153-162 (1977).
15. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260, 3440-3450 (1985).
16. V. Herzog, H. Reggio: Pathways of endocytosis from luminal plasma membrane in rat exocrine pancreas. Eur. J. Cell Biol. 21, 141-150 (1980).
17. Lisanti, M. P., I. W. Caras, M. A. Davitz, E. A. Rodriguez-Boulan: A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells. J. Cell Biol. 109, 2145-2156 (1989).
18. Matozaki, T., J. A. Williams: Multiple sources of 1,2-diacylglycerol in isolated rat pancreatic acini stimulated by cholecystokinin. J. Biol. Chem. 264, 14729-14734 (1989).
19. 3 transporters. J. Biol. Chem. 265, 12806-12812 (1990).
20. 2+. J. Cell Biol. 109, 2801-2808 (1989).
21. Paul, E., F. A. Leblond, D. LeBel: In resting conditions, the pancreatic granule membrane protein GP-2 is secreted by cleavage of its glycosylphosphatidylinositol anchor. Biochem. J. 277, 879-881 (1991).
22. Raymond, F. D., D. W. Moss, D. Fisher: Phase partitioning detects differences between phospholipase-released forms of alkaline phosphatase - a GPI-linked protein. Biochim. Biophys. Acta 1156, 117-122 (1993).
23. Rhee, S. G., Y. S. Bae: Regulation of phosphoinositide-specific phospholipase C isozymes. J. Biol. Chem. 272, 15045-15048 (1997).
24. Romagnoli, P., V. Herzog: Reinternalization of secretory proteins during membrane recycling in rat pancreatic acinar cells. Eur. J. Cell Biol. 44, 167-175 (1987).
25. Saltiel, A. R., P. Sherline, J. A. Fox: Insulin-stimulated diacylglycerol production results from the hydrolysis of a novel phosphatidylinositol glycan. J. Biol. Chem. 262, 1116-1121 (1987).
26. Saluja, A. K., R. K. Dawra, M. M. Lerch, M. L. Steer: CCK-JMV-180, an analog of cholecystokinin, releases intracellular calcium from an inositol trisphosphate-independent pool in rat pancreatic acini. J. Biol. Chem. 267, 11202-11207 (1992).
27. Sandvig, K., S. Olsnes, O. W. Petersen, B. van Deurs: Acidification of the cytosol inhibits endocytosis from coated pits. J. Cell Biol. 105, 679-689 (1987).
28. Scheele, G. A., S.-I. Fukuoka, S. D. Freedman: Role of the GP2/ THP family of GPI-anchored proteins in membrane trafficking during regulated exocrine secretion. Pancreas 9, 139-149 (1994).