Comparison of Diane 35 and Diane 35 plus spironolactone in the treatment of hirsutism

Fertility and Sterility

Volumn 69, Issue 1, 1998, Pages 66-69

  Keleştimur, Fahrettin ^a   Şahin, Yilmaz ^a  

^a ERCIYES UNIVERSITY   (Turkey)

Author keywords

Diane 35; Hirsutism; Spironolactone

Indexed keywords

ANDROSTENEDIONE; CYPROTERONE ACETATE; DIANE; ETHINYLESTRADIOL; PRASTERONE; PROLACTIN; SEX HORMONE BINDING GLOBULIN; SPIRONOLACTONE; TESTOSTERONE;

ADOLESCENT; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; HIRSUTISM; HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 0031882554     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(97)00427-5     Document Type: Article

References (17)

1. 1. McCenna TJ. The use of anti-androgens in the treatment of hirsutism. Clin Endocrinol 1991;35:1-3.
2. 2. Rittmaster RS, Thompson DL. Effect of leuprolide and dexamethasone on hair growth and hormone levels in hirsute women: The relative importance of the ovary and the adrenal in the pathogenesis of hirsutism. J CLin Endocrinol Metab 1990;70:1096-102.
3. 3. Givens JR. Role of oral contraceptives in the treatment of hyperandrogenism of hirsute women. In: Mahesh VB, Greenblatt RB, editors. Hirsutism and virilism: Pathogenesis, diagnosis and treatment. Boston: John Wright, PSG Inc., 1983:351-67.
4. 4. Miller JA, Jacobs HS. Treatment of hirsutism and acne with cyproterone acetate. Clin Endocrinol Metab 1986;15:373-89.
5. 5. Brooks JR. Treatment of hirsutism with 5 α-reductase inhibitors. Clin Endocrinol Metab 1986;15:391-405.
6. 6. Schriock EA, Schriock ED. Treatment of hirsutism. Clin Obstet Gynecol 1991;34:852-63.
7. 7. Hammerstein J, Meckies J, Leo-Rossberg I. Use of cyproterone acetate (CPA) in the treatment of acne, hirsutism and virilism. J Steroid Biochem Mol Biol 1975;6:827-36.
8. 8. Keleştimur F, Şahin Y, Turan R, Ayata D. A comparison of Diane 35 plus spironolactone and diane 35 in the treatment of hirsutism (Abstract). J Endocrinol 1993;139(Suppl):91.
9. 9. New MI, Lorenzen F, Lerner AJ, Kohn B, Oberfield SE, Pollack MS, et al. Genotyping steroid 21-hydroxylase deficiency: hormonal reference data. J Clin Endocrinol Metab 1983;57:320-6.
10. 10. Hatch R, Rosenfield RL, Kim MH, Tredway D, Hirsutism: Implications, etiology, and management. Am J Obstet Gynecol 1981;140:815-30.
11. 11. Casey JH, Moxham A, Nabarro JDN. Idiopathic hirsutism: Seasonal variation of hair growth and response 10 estrogen administration. Lancet 1964;i:587-8.
12. 12. Jeffcoate W. The treatment of women with hirsutism. Clin Endocrinol 1993;39:143-50.
13. 13. Eil C, Edelson SK. The use of human skin fibroblasts to obtain potency estimates of drug binding to androgen receptors. J Clin Endocrinol Metab 1984;59:51-5.
14. 14. Carmina E, Lobo RA. Peripheral androgen blockade versus glandular androgen suppression in the treatment of hirsutism. Obstet Gynecol 1991;78:845-9.
15. 15. Lobo RA, Shoupe D, Serafini P, Brinton D, Horton R. The effects of two doses of spironolactone on serum androgens and anagen hair in hirsute women. Fertil Steril 1985;43:200-5.
16. 16. Camming DC, Yang JC, Rebar RW, Yen SC. Treatment of hirsutism with spironolactone. J Am Med Assoc 1982;247:1295-8.
17. 17. Ylöstalo P, Heikkinen J, Kauppila A, Pakarinen A, Jarvinen PA. Low dose spironolactone in the treatment of female hirsutism. Int J Fertil 1987;32:41-5.