Subsyndromes in chronic schizophrenia. A contribution to the heterongeneity of schizophrenic psychoses;Subsyndrome der chronischen Schizophrenie - Ein Beitrag zur Heterogenitat schizophrener Psychosen

Fortschritte der Neurologie Psychiatrie

Volumn 66, Issue 1, 1998, Pages 15-31

  Schroder J ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CORPUS CALLOSUM; DELUSION; FRONTAL CORTEX; HUMAN; NEUROPSYCHOLOGY; PARIETAL LOBE; SCHIZOPHRENIA; SYNDROME DELINEATION;

EID: 0031882430     PISSN: 07204299     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-995235     Document Type: Article

References (127)

1. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders. 3rd ed., revised. DC: American Psychiatric Press, Washington 1980
2. American Psychiatric Association: DSM-III-R: Diagnostic and Statistical Manual of Mental Disorders. 3rd ed., revised. DC: American Psychiatric Press, Washington 1987
3. Anderson, J. A., J. W. Silverstein, S. A. Ritz, R. S. Jones: Distinctive features, categorial perception, and probability learning: Some applications of a neural model. Psychol. Rev. 84 (1977) 413-451
4. Andreasen, N. C.: The scale for the assessment of negative symptoms (SANS). The University of Iowa. Iowa City. Iowa 1983 a
5. Andreasen, N. C.: Comprehensive assessment of symptoms and history (CASH): The University of Iowa College of Medicine. Iowa City, Iowa 1983 a
6. Andreasen, N. C., M. Flaum, V. Swayze, G. Tyrell, S. Arndt: Positive and negative symptoms in schizophrenia. A critical reappraisal. Arch. Gen. Psychiatry 47 (1990) 615-621
7. Andreasen, N. C., K. Rezai, R. Alliger, V. W. Swayze II, M. Flaum, P. Kirchner, G. Cohen, D. S. O'Leary: Hypofrontality in neuroleptic naive patients and in patients with chronic schizophrenia: assessment with xenon 133 single photon emission computed tomography and the tower of London. Arch. Gen. Psychiatry 49 (1992) 943-958
8. Andreasen, N. C., S. Arndt, R. Alliger, D. Miller, M. Flaum: Symptoms of schizophrenia: methods meaning, and mechanism. Arch. Gen. Psychiatry 52 (1995) 341-351
9. Arndt, S., R. A. Alliger, N. C. Andreasen: The distinction of positive and negative symptoms. The failure of a two dimensional model. Br. J. Psychiatry 158 (1991) 317-322
10. Arndt, S., N. C. Andreasen, M. Flaum, D. Miller, P. Nopoulos: A longitudinal study of symptom dimensions in schizophrenia. Arch. Gen. Psychiatry 52 (1995) 352-360
11. Aubin, F., Y. Lecrubier, P. Boyer: Principal component factor analysis of the SANS. Biol. Psychiatry 29 (1991) 333S-701S
12. Basset, A. S., A. Bury, W. G. Honer: Testing Liddle's three-syndrome model in families with schizophrenia. Schizophr. Res. 12 (1994) 213-221
13. Becker, T., K. Elmer, B. Mechela, F. Schneider, S. Taubert, G. Schroth, W. Grodd, M. Bartels, H. Beckmann: MRI findings in medial temporal lobe structures in schizophrenia. Eur. J. Neuropsychopharmacology 1 (1990) 83-86
14. Benes, F. M., J. McSparren, E. Bird, J. P. SanGiovianni, S. L. Vincent: Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients. Arch. Gen. Psychiatry 48 (1991) 996-1001
15. Benton, B.: Der Benton-Test. Handbuch. Huber-Verlag, Bern 1981
16. Bleuler, E.: Dementia praecox oder die Gruppe der Schizophrenien. In: Aschaffenburg, G. (ed.): Handbuch der Psychiatrie. Spezieller Teil 4. Abt. 1. Hälfte. Franz Deuticke, Leipzig, Wien 1911
17. Bilder, R. M., S. Mukherjee, R. O. Rieder, A. K. Pandurangi: Symptomatic and neuropsychological components of defect states. Schizophr. Bull. 11 (1985) 409-419
18. Bogerts, B., M. Ashtari, G. Degreef, J. M. Alvir, R. M. Bilder, J. A. Liebermann: Reduced temporal limbic structure volumes on magnetic resonance images in first episode schizophrenia. Psychiatry Res: Neuroimaging 35 (1990) 1-13
19. Bogerts, B.: Recent advances in the neuropathology of schizophrenia. Schizophr. Bull. 19 (1993) 431-445
20. Breier, A., R. W. Buchanan, A. Elkashef, R. C. Munson, B. Kirkpatrick, F. Gellad: Brain morphology and schizophrenia. Arch. Gen. Psychiatry 49 (1992) 921-926
21. Brickenkamp, A. L.: Aufmerksamkeits-Belastungs-Test. Hogrefe-Verlag, Göttingen 1981
22. Brown, K. W., T. White: Syndromes of chronic schizophrenia and some clinical correlates. Br. J. Psychiatry 161 (1992) 317-322
23. Buchsbaum, M. S., R. O. Rieder: Biologic heterogeneity and psychiatric research. Platelet MAO activity as a case study. Arch. Gen. Psychiatry 36 (1979) 1163-1169
24. Buchsbaum, M. S., H. H. Holcomb, L. E. DeLisi, J. Cappelletti, A. C. King, J. Johnson, E. Hazlett, R. M. Post, J. Morihisa, W. Carpenter, R. Cohen, D. Pickar, R. Kessler: Anteroposterior gradient in glucose use in schizophrenia and affective disorders. Arch. Gen. Psychiatry 41 (1984) 1159-1166
25. Buchsbaum, M. S., J. C. Wu, I. E. DeLisi, H. H. Holcomb, E. Hazlett, K. Cooper-Langston, R. Kessler: Positron emission tomography studies of basal ganglia and somatosensory cortex neuroleptic drug effects: differences between normal controls and schizophrenic patients. Biol. Psychiatry 22 (1997) 479-494
26. Buchsbaum, M. S.: The frontal lobes, basal ganglia and temporal lobes as sites for schizophrenia. Schizophr. Bull. 16 (1990) 379-389
27. Buchsbaum, M. S., St. G. Potkin, B. V. Siegel, J. Lohr, M. Katz, L. A. Gottschall, B. Gulasekaram, J. F. Marshall, St. Lottenberg, Ch. Y. Ten, L. Abel, L. Pion, W. E. Bunney: Striatal metabolic rate and clinical response to neuroleptics in schizophrenia. Arch. Gen. Psych. 49 (1992) 966-974
28. Busatto, G. F., L. S. Pilowsky, D. C. Costa, P. J. Ell, A. S. Davis, J. V. Lucey, R. W. Robert: Reduced in vivo benzodiazepine receptor binding correlates with severity of psychotic symptoms in schizophrenia. Am. J. Psychiatry 154 (1997) 56-63
29. Cantor-Graae, E., S. Warkentin, G. Franzen, ? Risberg, D. H. Ingvar: Aspects of stability of regional cerebral blood flow in chronic schizophrenia: an 18-year followup study. Psychiatry Res. Neuroimaging 40 (1991) 253-266
30. Carpenter, W. T. Jr., D. W. Heinrichs, L. D. Alphs: Treatment of negative symptoms. Schizophr. Bull. 11 (1985) 440-452
31. Chua, S. E., I. C. Wright, J. B. Poline, P. F. Liddle, R. M. Murray, R. S. J. Frackowiak, K. J. Friston, P. K. McGuire: Greymatter correlates of syndromes in schizophrenia. Br. J. Psychiatry 170 (1997) 406-410
32. Churchland, P. S., T. J. Sejnowski: The computational brain. The MIT press: Cambridge/MA, London/England 1992
33. Cornblatt, B. A., N. J. Risch, G. Faris, D. Friedman, L. Erlenmeyer-Kimling: The Continuous Performance Test, Identical Pairs Version (CPT-IP): new findings about sustained attention in normal families. Psychiatry Res. 26 (1988) 223-238
34. Cornblatt, B. A., M. F. Lenzenweger, L. Erlenmeyer-Kimling: The Continuous Performance Test, Identical Pairs Version (CPT-IP): II. Contrasting attentional profiles in schizophrenic and depressed patients. Psychiatry Res. 29 (1989) 65-86
35. Crow, T. J.: Molecular pathology of schizophrenia: More than one disease process? British Medical Journal 280 (1980) 66-68
36. Crow, T. J.: The two-syndrome concept: origins and current status. Schizophr. Bull. 11 (1985) 471-485
37. Cuesta, M. J., V. Peralta: Psychopathological dimensions in schizophrenia. Schizophr. Bull. 21 (1995) 473-482
38. David, A. S., P. W. Woodruff, R. Howard, J. D. Mellers, M. Brammer, E. Bullmore, I. Wright, C. Andrew, S. C. Williams: Auditory hallucinations inhibit exogenous activation of auditory association cortex. Neuroreport 7 (1996) 932-936
39. Ebert, D., H. Feistel, A. Barocka, W. Kaschka, T. Mokrusch: A testretest study of cerebral blood flow during somatosensory stimulation in depressed patients with schizophrenia and major depression. Eur. Arch. Psychiatry Clin. Neurosci. 242 (1993) 250-254
40. 99mTc-Exametazime in unmedicated schizophrenic patients. Biol. Psychiatry 33 (1993) 487-495
41. Endicott, J., R. L. Spitzer: A diagnostic Interview: The Schedule for Affective Disorders and Schizophrenia. Arch. Gen. Psychiatry 35 (1978) 837-844
42. Erzigkeit, H.: Manual zum SKT, von A-E. 2. neubearbeitete Auflage. Vless-Verlagsgesellschaft, Darmstadt 1986
43. Falkai, P., B. Bogerts: Cell loss in the hippocampus of schizophrenics. Europ. Arch. Psychiatry Neurol. 236 (1986) 154-161
44. Geider, F. J., K.-E. Rogge, H. P. Schaaf: Einstieg in die Faktorenanalyse. Quelle und Meyer, Heidelberg 1982
45. Geider, F. J.: Basiskarte: Ergebnisse. In: Rogge, K. E. (ed.): Methodenatlas. Springer Verlag, Heidelberg, Berlin, New York, 1995
46. Goldberg, T. E., E. S. Torrey, J. M. Gold, J. E. Ragland, L. C. Bigelow, D. R. Weinberger: Learning and memory in monozygotic discordant for schizophrenia. Psychol. Med. 23 (1993) 71-85
47. Goldmann-Rakic, P. S.: Prefrontal dysfunction in schizophrenia: The relevance of working memory. In: Psychopathology and the brain. Eds: Caroll B. J. und Barett J. E. Raven Press, New York 1991
48. Gunther, W., R. Petsch, R. Steinberg, E. Moser, P. Streck, H. Heller, G. Kurtz, H. Hippius: Brain dysfunction during motor activation and corpus callosum alterations in schizophrenia measured by cerebral blood flow and magnetic resonance imaging. Biol. psychiatry 29 (1991) 535-555
49. Günter, W., J. D. Brodie, E. L. Bartlett, S. L. Dewey, F. A. Henn, N. D. Volkow, K. Alper, A. Wolkin, R. Cancro, A. P. Wolf: Diminished cerebral metabolic response to motor stimulation in schizophrenics: a PET study. Eur. Arch. Psychiatry Clin. Neurosci. 244 (1994) 115-125
50. Gur, R. E., P. D. Mozley, S. M. Resnick, St. Levick, R. Erwin, A. J. Saykin, R. C. Gur: Relations among clinical scales in schizophrenia. Am. J. Psychiatry 148 (1991) 472-474
51. Häfner, H., K. Maurer: Are there two types of schizophrenia? True onset and sequence of positive and negative syndromes prior to first admission. In: Marneros, A., N. C. Andreasen, M. T. Tsuang (eds.): Negative versus positive schizophrenia. Springer-Verlag, New York, Berlin, Heidelberg, London, Paris, Tokyo 1991
52. Heckers, S., H. Heinsen, B. Geiger, H. Beckmann: Hippocampal neuron number in schizophrenia. A stereological study. Arch. Gen. Psychiatry 48 (1991) 1002-1008
53. Hornstein, C., P. Richter, A. Mortimer, A. Will, A. Beuth, I. Müller-Wulff, H. Sauer: Dimensionen der Schizophrenie im Alter - Korrelationen mit kognitiven und motorischen Auffälligkeiten. Nervenarzt 67 (1996) 58
54. Horwitz, B., R. Duara, S. I. Rapoport: Age differences and intercorrelations between regional cerebral metabolic rates for clucose. Brain. Res. 407 (1986) 294-306
55. Huber, G.: Reine Defektsyndrome und Basis-Stadien endogener Psychosen. Fortschr. Neurol. Psychiatr. 34 (1966) 409-426
56. Hunter, W. S.: A consideration of Lashley's theory of the equipotentiality of cerebral action. J. Gen. Psychol. 3 (1930) 455-468
57. Ingvar, D. H., G. Franzen: Abnormalities of cerebral blood flow distribution in patients with chronic schizophrenia. Acta Psychiatr. Scand. 50 (1974) 425-462
58. Jahn, Th., J. Schröder, W. Hubmann, F. Mohr, M. Karr, R. Cohen: Neurological soft signs and extrapyramidal side effects in schizophrenia. Psychiatry Res. (zur Veröffent. eingereicht)
59. Johnstone, E. C., T. J. Crow, C. D. Frith, J. Husband, L. Kreel: Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet II (1976) 924-926
60. Johnstone, E. C., T. J. Crow, C. D. Frith, M. W. P. Carney, J. S. Price: Mechanism of the antipsychotic effect in the treatment of acute schizophrenia. Lancet I (1978) 848-851
61. Kaplan, R. D., H. Szechtman, S. Franco, B. Szechtman, C Nahmias, E. S. Garnett, S. List, J. M. Cleghorn: Three clinical syndromes of schizophrenia in untreated subjects: relation to brain glucose activity measured by positron emission tomography (PET). Schizophr. Res. 11 (1993) 47-54
62. Karr, M., J. Schröder, A. Tittel: Neurologische soft signs und neuropsychologische Störungen bei schizophrenen Psychosen. Nervenheilkunde 15 (1996) 326-331
63. Kawasaki, Y., Y. Maeda, N. Sakai, M. Higashima, N. Yamaguchi, Y. Koshino, K. Hisada, M. Suzuki, H. Matsuda: Regional cerebral blood flow in patients with schizophrenia: relevance to symptom structures. Psych. Res: Neuroimaging 67 (1996) 49-58
64. Kay, S. R., A. Fiszbein, L. A. Poler: The positive and negative syndrome scale (PAN SS) for schizophrenia. Schizophr. Bull. 13 (1987) 261-276
65. Kay, S. R.: Significance of the positive-negative distinction in schizophrenia. Schizophr. Bull. 16 (1990) 635-651
66. Kay, S. R., S. Sevy: Pyramidal model of schizophrenia. Schizophr. Bull. 16 (1990) 537-545
67. Kendler, K. S., A. M. Gruenberg, M. T. Tsuang: A family study of the subtypes of schizophrenia. Am. J. Psychiatry 145 (1988) 57-62
68. Klimidis, S., G. W. Stuart, I. H. Minas, D. L. Copolov, B. S. Singh: Positive and negative symptoms in the psychoses Re-analysis of published SAPS and SANS global rating. Schizophr. Res. 9 (1993) 11-18
69. Klosterkötter, J.: Basissymptome und Endphänomene der Schizophrenie. Springer-Verlag, Berlin, Heidelberg 1988
70. Kolakowska, T., A. O. Williams, M. Ardern, M. A. Reveley, K. Jambor, M. G. Gelder, B. M. Mandelbrote: Schizophrenia with good and poor outcome. I: early clinical features, response to neuroleptics and signs of organic dysfunction. Br. J. Psychiatry 146 (1985) 229-246
71. Kulhara, P., K. Chandiramani: Positive and negative subtypes of schizophrenia. A follow-up study from India. Schizophr. Res. 3 (1990) 107-116
72. Kulhara, P., S. K. Kota, S. Joseph: Positive and negative subtypes of schizophrenia. A study from India. Acta Psychiatr. Scand. 74 (1986) 353-359
73. Lashley, K. S.: Brain mechanisms and intelligence. A quantitative study of the injuries to the brain. The University of Chicago press, Chicago 1929
74. Liddle, P. F.: The symptoms of chronic schizophrenia. A re-examination of the positive-negative dichotomy. Br. J. Psychiatry 151 (1987a) 145-151
75. Liddle, P. F.: Schizophrenic symptoms, cognitive performance and neurological dysfunction. Psychol. Med. 17 (1987b) 49-57
76. Liddle, P. F., T. R. E. Barnes: Syndromes of Chronic Schizophrenia. Br. J. Psychiatry 157 (1991) 558-561
77. Liddle, P. F., D. L. Morris: Schizophrenic syndromes and frontal lobe performance. Br. J. Psychiatry 158 (1991) 340-345
78. Liddle, P. F., K. J. Friston, C. D. Frith, S. R. Hirsch, T. Jones, R. S. J. Frackowiak: Patterns of cerebral blood flow in schizophrenia. Br. J. Psychiatry 160 (1992) 179-186
79. Lindenmayer, J.-P., R. Bernstein-Hyman, S. Grochowski, N. Bark: Psychopathology of schizophrenia: initial validation of a 5-factor model. Psychopathology 28 (1995) 22-31
80. Mathew, R. J., W. H. Wilson, S. R. Tant, L. Robonson, R. Prakash: Abnormal resting regional cerebral blood flow patterns and their correlates in schizophrenia. Arch. Gen. Psychiatry 45 (1988) 542 -549
81. McGhie, A., J. Chapman: Disorders of attention and perception in early schizophrenia. Arch. Gen. Psychiatry 6 (1962) 17-33
82. Milner, B.: Effects of different brain lesions on card sorting. Arch. Neurol. 9 (1963) 100-110
83. Mundt, Ch: Das Apathiesyndrom der Schizophrenen. Springer Verlag, Berlin, Heidelberg, New York, Tokyo 1985
84. Mundt, Ch.: Die psychopathologischen Grundlagen zur Psychopathometrie des schizophrenen Residualsyndroms. Fundamenta Psychiatr. 3 (1989) 2-11
85. Mundt. Ch., P. Fiedler, B. Pracht, R. Rettig: InSka (Intentionalitäts-Skala) - ein neues psychometrisches Instrument zur quantitativen Erfassung der schizophrenen Residualsymptomatik. Nervenarzt 56 (1985) 146-149
86. Mundt, Ch., S. Kasper, M. Huerkamp: The diagnostic specificity of negative symptoms and their psychopathological context. Br. J. Psychiatry 155 (1989) 32-36
87. Norman, R. M. G., A. K. Malla, S. L. Morrison-Stewart, E. Helmes, P. C. Williamson, J. Thomas, L. Cortese: Neuropsychological correlates of syndromes in schizophrenia. Br. J. Psychol. 170 (1997) 134-139
88. Nuechterlein, K. H., R. Parasuraman, Q. Jiang: Visual sustained attention: Image degradation produces rapid decrement over time. Science 220 (1983) 327-329
89. Overall, J. E., D. R. Gorham: The Brief Psychiatric Rating Scale. Psychol. Rep. 10 (1962) 799-812
90. Owens, D. G. C., E. C. Johnstone, C. D. Frith: Spontaneous involuntary disorders of movement. Arch. Gen. Psychiatry 39 (1982) 452-461
91. Peralta, V., J. de Leon, M. J. Cuesta: Are there more than two syndromes in schizophrenia? A critique of the positive-negative dichotomy. Br. J. Psychiatry 161 (1992) 335-343
92. Peralta, V., M. J. Cuesta, J. de Leon: An empirical analysis of latent structures underlying schizophrenic symptoms: a Four-Syndrome Model. Biol. Psychiatry 36 (1994) 726-736
93. Phillips, Mr., W. Xiong, R. W. Wang, Y. H. Gao, X. Q. Wang, N. P. Zang: Reliability and validity of the Chinese versions of the Scale for Assessment of Positive and Negative Symptoms. Acta Psychiatr. Scand. 84 (1991) 364-370
94. Sabri, O., R. Erkwoh, M. Schreckenberger, U. Cremerius, G. Schulz, C. Dickmann, H. J. Kaiser, E. M. Steinmeyer, H. Saß, U. Buell: Regional cerebral blood flow and negative/positive symptoms in 24 drug-naive schizophrenics. J. Nucl. Med. 38 (1997) 181-188
95. Saint- Cyr, J. A., A. E. Taylor, A. E. Lang: Procedural learning and neostriatal dysfunction imman. Brain 190 (1988) 941-959
96. Sartori, G.: From neuropsychological data to theory and viceversa. In: Denes, G., P. Bisiacchi, C. Semenza, E. Andrewsky (Eds.): Perspectives in cognitive neuropsychology. Erlbaum, London 1988
97. Saß, H.: The Historical Evolution of the Concept of Negative Symptoms in Schizophrenia. Br. J. Psychiatry 155 (1989) 26-31
98. Saykin, A. J., R. C. Gur, R. E. Gur, D. Mozley, L. H. Mozley, S. M. Resnick, B. Rester, P. Stafiniak: Neuropsychological function in schizophrenia. Selective impairment in memory and leaming, Arch. Gen. Psychiatry 48 (1991) 618-624
99. 99mTc-HMPAO-SPECT pilot study. Psychiatry Res. 29 (1989) 331-333
100. Schröder, J., F. J. Geider, M. Binkert, Ch. Reitz, M. Jauß, H. Sauer: Subsyndromes in chronic schizophrenia: do their psychopathological characteristics correspond to cerebral alterations? Psychiatry Res. 42 (1992a) 209-220
101. Schröder, J., R. Niethammer, F.-J. Geider, Ch. Reitz, M. Binkert, M. Jauß, H. Sauer: Neurological soft signs in schizophrenia. Schizophr. Res. Band 6 (1992b) 25-30
102. Schröder, J., P. Richter, F.-J. Geider, R. Niethammer, M. Binkert, Ch. Reitz, H. Sauer: Diskrete neurologische und sensorische Störungen (neurologische soft signs) im Akutverlauf endogener Psychosen. Z. Klin. Psychol. Psychopathologie Psychotherapie 41 (1993) 190-206
103. Schröder, J., M. S. Buchsbaum, B. V. Siegel, F. J. Geider, R. J. Maier, J. Lohr, J. Wu, S. G. Potkin: Patterns of cortical activity in schizophrenia. Psychol. Med. 24 (1994) 947-955
104. Schröder, J.: Subsyndrome der chronischen Schizophrenie: Untersuchungen mit bildgebenden Verfahren zur Heterogenität schizophrener Psychosen. Springer Verlag, Heidelberg, Berlin, New York, London (im Druck)
105. Schröder, J., F. Wenz, K. Baudendistel, L. R. Schad, M. V. Knopp: Sensorimotor cortex and supplementary motor area changes in schizophrenia: a study with functional magnetic resonance imaging. Br. J. Psychiatry 167 (1995) 197-201
106. Schröder, J., M. S. Buchsbaum, B. V. Siegel, F. J. Geider, J. Lohr, Ch. Tang, J. Wu, St. G. Potkin: Cerebral metabolic activity correlates of subsyndromes in chronic schizophrenia. Schizophr. Res. 19 (1996a) 41-53
107. Schröder, J., A. Tittel, A. Stockert, M. Karr: Memory deficits in subsyndromes of chronic schizophrenia. Schizophr. Res. 21 (1996b) 19-26
108. Schröder, J., B. Bubeck, S. Demisch, H. Sauer: Benzodiazepine receptor distribution and diazepam binding in schizophrenia: an exploratory study. Psychiatry Res: Neuroimaging 68 (1997) 125-131
109. 123I-IBZM SPECT in the drug-naive state and after neuroleptic treatment. Biol. Psychiatry, 1997 (im Druck)
110. Shenton, M. E., R. Kikinis, F. A. Jolesz, S. D. Pollak, M. LeMay, C. G. Wible, H. Hokama, J. Martin, D. Metcalf, M. Coleman, R. W. McCarley: Abnormalities of the left temporal lobe and thought disorder in schizophrenia. A quantitative magnetic resonance imaging study. New England J. Medicine 327 (1992) 604-612
111. Spitzer, M.: The psychopathology, neuropsychology, and neurobiology of associative and working memory in schizophrenia. Eur. Arch. Psychiatry Clin. Neurosci. 243 (1993) 57-70
112. Squire, L. R.: Mechanisms of Memory. Science 232 (1986) 1612 -1619
113. Suddath, R. L., G. W. Christison, E. F. Torrey, M. F. Casanova, D. R. Weinberger: Anatomical abnormalities in the brains of monocygotic twins discordant for schizophrenia. N. Engl. J. Med. 322 (1990) 789-794
114. Tamminga, C. A., G. K. Thaker, R. Buchanan, B. Kirkpatrick, L. D. Alphs, T. N. Chase, W. T. Carpenter: Limbic system abnormalities identified in schizophrenia using positron emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome. Arch. Gen. Psychiatry 49 (1992) 522-530
115. Teuber, H. L.: Physiological psychology. An Rev. Psychology 9 (1955) 267-296
116. Toomey, R., S. Kremen, J. C. Simpson, J. A. Samson, L. J. Seidman, M. J. Lyons, S. V. Faraone, M. T. Tsuang: Revisiting the factor structure for positive and negative symptoms: evidence from a large heterogenous group of psychiatric patients. Am. J. Psychiatry 154 (1997) 371-377
117. Vogel, H.: Maße und Normwerte in der Computertomographie. Ecomed Verlagsgesellschaft, Landsberg/Lech 1986
118. Volkow, N. D., L. R. Tancredi: Biological correlates of mental activity studied with PET. Am. J. Psychiatry 148 (1991) 439-443
119. Volkow, N. D., A. P. Wolf, P. van Gelder, J. D. Brodie, J. E. Overall, R. Cancro, F. Gomez-Mont: Phenomenological correlates of metabolic activity in 18 patients with chronic schizophrenia. Am. J. Psychiatry 144 (1987) 151-158
120. Weinberger, D. R.: Anteromedial temporal-prefrontal connectivity; a functional neuroanatomical system implicated in schizophrenia. In: Caroll, B. J., J. E. Barett (eds.): Psychopathological and the brain. Raven Press, New York 1991
121. Weinberger, D. R., K. F. Berman, B. P. Illowsky: Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. Arch. Gen. Psychiatry 45 (1988) 609-615
122. weinberger, D. R., K. F. Berman, R. Suddath, E. F. Torrey: Evidence of dysfunction of a prefrontal-limbic network in schizophrenia: A magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins. Am. J. Psychiatry 149 (1992) 890-895
123. Wolkin, A., J. Jaeger, J. D. Brodie, A. P. Wolf, J. Fowler, J. Rotrosen, F. Gomez-Mont, R. Cancro: Persistence of cerebral metabolic abnormalities in chronic schizophrenia as determined by positron emission tomography. Am. J. Psychiatry 142 (1985) 564-571
124. Wolkin, A., M. Sanfilipo, A. P. Wolf, B. Angrist, J. D. Brodie, J. Rotrosen: Negative symptoms and hypofrontality in chronic schizophrenia. Arch. Gen. Psychiatry 49 (1992) 959-965
125. Wood, C. C.: Variations on a theme by Lashley: lesions experiments on the neural model of Anderson, Silverstein, Ritz und Jones. Psychol. Rev. 85 (1978) 582-591
126. Woodruff, P. W. R., M. L. Phillips, T. Rushe, I. C. Wright, R. M. Murray, A. S. David: Corpus callosum size and inter-hemispheric function in schizophrenia. Schizophr. Res. 23 (1997) 189-196
127. Wu, J.-Y., L. B. Cohen, C. X. Falk: Neuronal Activity During Different Behaviors in Aplysia: A Distributed Organization? Science 263 (1994) 820-823