Regulation of human immunodeficiency virus replication by 2',5'- oligoadenylate-dependent RNase L

Journal of Virology

Volumn 72, Issue 2, 1998, Pages 1146-1152

  Maitra, Ratan K ^a   Silverman, Robert H ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2',5' OLIGOADENYLIC ACID; ALPHA INTERFERON; RIBONUCLEASE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL DEATH; GENE DELETION; HUMAN IMMUNODEFICIENCY VIRUS; LONG TERMINAL REPEAT; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; VIRUS GENE; VIRUS REPLICATION;

EID: 0031882216     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.2.1146-1152.1998     Document Type: Article

References (48)

1. Adachi, A., H. E. Gendelman, S. Koenig, T. Folks, R. Willey, A. Robon, and M. A. Martin. 1986. Production of acquired immunodeficiency syndrome-associated retrovirus in human and non-human cells transfectcd with an infectious molecular clone. J. Virol. 59:284-289.
2. Badley, A. D., J. A. Mcelhinny, P. J. Leibson, D. H. Lynch, M. R. Alderson, and C. V. Paya. 1996. Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T Lymphocytes. J. Virol. 70:199-206.
3. Benkirane, M., C. Neuveut, R. F. Chun, S. M. Smith, C. E. Samuel, A. Gatignol, and K. T. Jeang. 1997. Oncogenic potential of TAR RNA binding protein TRBP and its regulatory interaction with RNA-dependent protein kinase PKR. EMBO J. 16:611-624.
4. Campioni, D., A. Corallini, G. Zauli, L. Possati, G. Altavilla, and G. Barbanti-Brodano. 1995. HIV type 1 extracellular Tat protein stimulates growth and protects cells of BK virus/tat transgenic mice from apoptosis. AIDS Res. Hum. Retroviruses 11:1039-1048.
5. Chakrabarty, B. K., R. K. Maitra, X.-Z. Ma, and H. W. Kestler. 1996. A candidate live inactivatable attenuated vaccine for AIDS. Proc. Natl. Acad. Sci. USA 93:9810-9815.
6. Chebath, J., P. Benech, M. Revel, and M. Vigneron. 1987. Constitutive expression of (2′-5′)oligo A synthetase confers resistance to picornavirus infection. Nature 330:587-588.
7. Coccia, E. M., G. Romeo, A. Nissim, G. Marziali, R. Albertini, E. Affabris, A. Battistini, G. Fiorucci, R. Orsatti, G. B. Rossi, and J. Chebath. 1990. A full-length murine 2-5A synthetase cDNA transfected in NIH-3T3 cells impairs EMCV but not VSV replication. Virology 179:228-233.
8. Coccia, E. M., B. Krust, and A. G. Hovenessian. 1994. Specific inhibition of viral protein synthesis in HIV-infected cells in response to interferon treatment. J. Biol. Chem. 269:23087-23094.
9. Cole, J. L., S. S. Carroll, and L. C. Kuo. 1996. Stoichiometry of 2′,5′-oligoadenylate-induced dimerization of ribonuclease L. J. Biol. Chem. 271: 3979-3981.
10. Diaz-Guerra, M., C. Rivas, and M. Esteban. 1997. Inducible expression of the 2-5A synthetase/RNase L system results in inhibition of vaccinia virus replication. Virology 227:220-228.
11. Dong, B., and R. H. Silverman. 1995. 2-5A-dependent RNase molecules dimerize during activation by 2-5A. J. Biol. Chem. 270:4133-4137.
12. Edery, I., R. Petryshyn, and N. Sonenberg. 1989. Activation of double-stranded RNA-dependent kinase (dsI) by the TAR region of HIV-1 mRNA: a novel translational control mechanism. Cell 56:303-312.
13. Finkel, T. H., G. Tudor-Williams, N. K. Banda, M. F. Cotton, T. Curiel, C. Monks, T. W. Baba, R. M. Ruprecht, and A. Kupfer. 1995. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV-and SIV-infected lymph nodes. Nature Med. 1:129-134.
14. Friedman, R. M., and P. M. Pitha. 1984. The effect of interferon on membrane associated virus, p. 319-336. In R. M. Friedman (ed.), Interferon 3: mechanism of production and action. Elsevier, Amsterdam, The Netherlands.
15. Gendelman, H. E., L. M. Baca, J. Turpin, D. C. Kalter, A. Hansen, C. W. Orenstein, C. W. Diffenbach, R. M. Friedman, and M. S. Meltzer. 1990. Regulation of HIV replication in infected monocytes by interferon α: mechanisms for viral restriction. J. Immunol. 145:2669-2676.
16. Hansen, B. D., P. L. Nara, R. K. Maheshwari, G. S. Sidhu, J. G. Bernbaum, D. Hoekzema, M. S. Meltzer, and H. E. Gendelman. 1992. Loss of infectivity by progeny virus from alpha interferon-treated human immunodeficiency virus type 1-infected T cells is associated with defective assembly of envelope gp120. J. Virol. 66:7543-7548.
17. Johnson, V. A., and R. E. Byington. 1990. Quantitative assays for virus infectivity, p. 71-76. In A. Aldovini and B. D. Walker (ed.), Techniques in HIV research. Stockton, New York, N.Y.
18. Kerr, I. M., and R. E. Brown. 1978. pppA2′p5′A2′p5′A2′p5′A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells. Proc. Natl. Acad. Sci. USA 75:256-260.
19. Laurent-Crawford, A. G., B. Krust, Y. Riviere, C. Desgranges, S. Muller, M. P. Kieny, C. Dauguet, and A. G. Hovanessian. 1993. Membrane expression of HIV envelope glycoproteins triggers apoptosis in CD4 cells. AIDS Res. Hum. Retroviruses 9:761-773.
20. Maitra, R. K., N. A. J. McMillan, S. Desai, J. McSwiggen, A. Hovanessian, G. Sen, B. R. G. Williams, and R. H. Silverman. 1994. HIV-1 TAR RNA has an intrinsic ability to activate interferon-inducible enzymes. Virology 204: 823-827.
21. Maitra, R. K., and B. R. G. Williams. Unpublished data.
22. McMillan, N. A. J., R. F. Chun, D. P. Siderovski, J. Galabru, W. M. Toone, C. E. Samuel, T. W. Mak, A. G. Hovanessian, K.-T. Jeang, and B. R. G. Williams. 1995. HIV-1 Tat directly interacts with interferon-induced, double-stranded RNA-dependent kinase, PKR. Virology 213:413-424.
23. Meurs, E. F., Y. Watanabe, S. Kadereit, G. N. Barber, M. G. Katze, K. Chong, B. R. G. Williams, and A. G. Hovanessian. 1992. Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth. J. Virol. 66:5805-5814.
24. Meylan, P. R., J. C. Guatelli, J. R. Munis, D. D. Richman, and R. S. Kornbluth. 1993. Mechanisms for the inhibition of HIV replication by interferon-α, -β, and -γ in primary human macrophages. Virology 193:138-148.
25. Pavlovic, J., H. A. Arzet, H. P. Hefti, M. Frese, D. Rost, B. Ernst, E. Kolb, P. Staeheli, and O. Haller. 1995. Enhanced virus resistance of transgenic mice expressing the human MxA protein. J. Virol. 69:4506-4510.
26. Pitha, P. 1991. Multiple effects of interferon on HIV-1 replication. J. Interferon Res. 11:313-318.
27. Poli, G., J. M. Orenstein, A. Kinter, T. M. Folks, and A. S. Fauci. 1989. Interferon alpha but not AZT suppresses HIV expression in chronically infected cell lines. Science 244:575-577.
28. Rysiecki, G., D. R. Gewert, and B. R. G. Williams. 1989. Constitutive expression of a 2′-5′-oligoadenylate synthetase cDNA results in increased antiviral activity and growth suppression. J. Interferon Res. 9:649-657.
29. Schneider-Schaulies, S., J. Schneider-Schaulies, A. Schuster, M. Bayer, J. Pavlovic, and V. T. Meulen. 1994. Cell-type-specific MxA-mediated inhibition of measles virus transcription in human brain cells. J. Virol. 68:6910-6917.
30. Schroder, H. C., D. Ugarkovic, H. Merz, Y. Kuchino, T. Okamoto, and W. E. G. Muller. 1990. Protection of HeLa-T4 cells against human immunodeficiency virus (HIV) infection after stable transfection with HIV LTR-2′-5′-oligoadenylate synthetase hybrid gene. FASEB J. 4:3124-3130.
31. Schroder, H. C., D. Ugarkovic, R. Wenger, P. Reuter, T. Okamoto, and W. E. G. Muller. 1990. Binding of Tat protein to TAR region of human immunodeficiency virus type-1 blocks TAR-mediated activation of (2′-5′) oligoadenylate synthetase. AIDS Res. Hum. Retrov. 6:659-672.
32. Schroder, H. C., R. Wenger, Y. Kuchino, and W. E. G. Muller. 1989. Modulation of nuclear matrix-associated 2′,5′-oligoadenylate metabolism and ribonuclease L activity in H9 cells by human immunodeficiency virus. J. Biol. Chem. 264:5669-5673.
33. Sengupta, D. N., and R. H. Silverman. 1989. Activation of interferon regulated dsRNA dependent enzymes by human immunodeficiency virus 1 leader RNA. Nucleic Acids Res. 17:969-978.
34. Shirazi, Y., and P. M. Pitha. 1992. Alpha interferon inhibits early stages of human immunodeficiency virus type 1 replication cycle. J. Virol. 66:1321-1328.
35. Silverman, R. H., and N. M. Cirino. 1997. RNA decay by the interferon-regulated 2-5A system as a host defense against viruses, p. 295-309. In J. B. Hartford and D. R. Morris (ed.), mRNA metabolism and posttranscriptional gene regulation. Wiley-Liss, Inc., New York, N.Y.
36. Sobol, R. W., W. L. Fisher, N. L. Reichenbach, A. Kumar, W. A. Beard, S. H. Wilson, R. Charubala, W. Pfleiderer, and R. J. Suhadolnik. 1993. HIV-1 reverse transcriptase: inhibition by 2′,5′-oligoadenylates. Biochemistry 32: 12112-12118.
37. Sobol, R. W., E. E. Henderson, N. Kon, J. Shao, P. Hitzges, E. Mordechai, N. L. Reichenbach, R. Charubala, H. Schirmeister, W. Pfleiderer, and R. J. Suhadolnik. 1995. Inhibition of HIV replication and activation of RNase L by phosphorothioate/phosphodiester 2′,5′-oligoadenylate derivatives. J. Biol. Chem. 270:5963-5978.
38. Su, Y., W. Popic, and P. M. Pitha. 1995. Inhibition of human immunodeficiency virus type-1 replication by a Tat-activated transduced interferon gene: targeted expression to human immunodeficiency virus type 1-infected cells. J. Virol. 69:110-121.
39. Torrence, P. F., R. K. Maitra, K. Lesiak, S. Khamnei, A. Zhou, and R. H. Silverman. 1993. Targeting RNA for degradation with a (2′-5′)oligoadenylate-antisense chimera. Proc. Natl. Acad. Sci. USA 90:1300-1304.
40. Vieillard, V., E. Lauret, V. Rousseau, and E. D. Maeter. 1994. Blocking of retroviral infection at a step prior to reverse transcription in cells transformed to constitutively express interferon β. Proc. Natl. Acad. Sci. USA 91:2689-2693.
41. Vilcek, J., and G. C. Sen. 1996. Interferon and other cytokines, p. 375-399. In B. N. Fields, D. N. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed. Lippincott-Raven, Philadelphia, Pa.
42. Wang, L., A. Zhou, S. Vasavada, B. Dong, H. Nie, J. M. Church, B. R. G. Williams, S. Banerjee, and R. H. Silverman. 1995. Elevated levels of 2′,5′-linked oligoadenylate-dependent ribonuclease L occur as an early event in colorectal tumorigenesis. Clin. Cancer Res. 1:1421-1428.
43. Westendorp, M. O., F. Rainer, C. Ochsenbauer, K. Stricker, J. Dhein, H. Walczak, K.-M. Debatin, and P. H. Krammer. 1995. Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120. Nature 375:497-500.
44. Youle, R. J., Y. N. Wu, S. M. Mikulski, K. Shogen, R. S. Hamilton, D. Newton, G. D'Alessio, and M. Gravell. 1994. RNase inhibition of human immunodeficiency virus infection of H9 cells. Proc. Natl. Acad. Sci. USA 91:6012-6016.
45. Zhao, H., B. B. De, T. Das, and A. K. Banerjee. 1996. Inhibition of human parainfluenza virus-3 replication by interferon and human MxA. Virology 220:330-338.
46. Zhou, A., B. A. Hassel, and R. H. Silverman. 1993. Expression cloning of 2-5A-dependent RNase - a uniquely regulated mediator of interferon action. Cell 72:743-765.
47. Zhou, A., J. Paranjape, T. L. Brown, H. Nie, S. Naik, B. Dong, A. Chang, B. Trapp, R. Fairchild, C. Colmenares, and R. H. Silverman. 1997. Interferon action and apoptosis are detective in mice devoid of 2′,5′-oligoadenylate dependent RNase L. EMBO J. 16:6355-6363.
48. Zhou, A., and R. H. Silverman. Unpublished data.