Effects of antioxidant vitamins C and E on atherosclerosis in lipid-fed rabbits

Cardiology

Volumn 89, Issue 3, 1998, Pages 189-194

  Sun, Yi Ping ^a   Zhu, Bo Qing ^a   Sievers, Richard E ^a   Norkus, Edward P ^a   Parmley, William W ^a,b   Deedwania, Prakash C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UCSF Medical Center at Parnassus   (United States)

Author keywords

tocopherol; Antioxidant; Ascorbic acid; Atherosclerosis

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; LIPID; LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTICLE; ATHEROSCLEROSIS; CHOLESTEROL DIET; CONTROLLED STUDY; LIPID BLOOD LEVEL; LIPID PEROXIDATION; MALE; NONHUMAN; OMENTUM; PRIORITY JOURNAL; PULMONARY ARTERY; RABBIT; VASCULAR LESION;

ANIMALS; ANTIOXIDANTS; AORTA, THORACIC; ARTERIOSCLEROSIS; ASCORBIC ACID; CHOLESTEROL; CHOLESTEROL, DIETARY; DISEASE MODELS, ANIMAL; DRUG COMBINATIONS; LIPOPROTEINS; MALE; OXIDATION-REDUCTION; PULMONARY ARTERY; RABBITS; RANDOM ALLOCATION; TRIGLYCERIDES; VITAMIN E;

EID: 0031881988     PISSN: 00086312     EISSN: None     Source Type: Journal    
DOI: 10.1159/000006786     Document Type: Article

References (44)

1. Florence TM: The role of free radicals in disease. Aust N Z J Ophthalmol 1995;23:3-7.
2. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL: Beyond cholesterol: Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 1989;320: 915-924.
3. Steinberg D, Witztum JL: Lipoproteins and atherogenesis: Current concepts. JAMA 1990; 264:3047-3052.
4. Steinberg D: Antioxidants and atherosclerosis: A current assessment. Circulation 1991;84: 1420-1425.
5. Rosenfeld ME, Palinski W, Ylä-Herttuala S, Butler S, Witztum JL: Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits. Arteriosclerosis 1990;10:336-349.
6. Regnström J, Nilsson J, Tomvall P, Landou C, Hamsten A: Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man. Lancet 1992;339:1183-1186.
7. Ascherio A, Stampfer MJ, Colditz GA, Rimm EB, Litin L, Willett WC: Correlations of vitamin A and E intakes with the plasma concentrations of carotenoids and tocopherols among American men and women. J Nutr 1992;122: 1792-1801.
8. Stryker WS, Kaplan LA, Stein EA, Stampfer MJ, Sober A, Willett WC: The relation of diet, cigarette smoking, and alcohol consumption to plasma beta-carotene and alpha-tocopherol levels. Am J Epidemiol 1988;127:283-296.
9. Blajchman MA, Senyi AF, Hirsh J, Genton E, George JN: Hemostatic function, survival, and membrane glycoprotein changes in young versus old rabbit platelets. J Clin Invest 1981;68: 1289-1294.
10. Sowell AL, Huff DL, Yeager PR, Caudill SP, Gunter EW: Retinol, alpha-tocopherol, lutein/ zeaxanthin, beta-cryptoxanthin, lycopene, alpha-carotene, trans-beta-carotene, and four retinyl esters in serum determined simultaneously by reversed-phase HPLC with multiwaveength detection. Clin Chem 1994;40:411-416.
11. Schmitz HH, Poor CL, Wellman RB, Erdman JW Jr: Concentrations of selected carotenoids and vitamin A in human liver, kidney and lung tissue. J Nutr 1991;121:1613-1621.
12. Gunter EW, et al: Laboratory Procedures used by the Clinical Chemistry Division, Centers for Disease Control, for the Second Health and Nutrition Examination Survey (HANES II) 1976-1980. IV. Analytical Methods, Vitamin C. Atlanta, USPHS, 1981, pp 17-19.
13. Rouleau J, Parmley WW, Stevens J, Wikman-Coffelt J, Sievers R, Mahley RW, Havel RJ: Verapamil suppresses atherosclerosis in cholesterol-fed rabbits. J Am Coll Cardiol 1983;1: 1453-1460.
14. Reaven PO, Khouw A, Beltz WF, Parthasarathy S, Witztum JL: Effect of dietary antioxidant combinations in humans. Protection of LDL by vitamin E but not by beta-carotene. Arterioscler Thromb 1993;13:590-600.
15. Brown KM, Morrice PC, Duthie GG: Vitamin E supplementation suppresses indexes of lipid peroxidation and platelet counts in blood of smokers and nonsmokers but plasma lipoprotein concentrations remain unchanged. Am J Clin Nutr 1994;60:383-387.
16. Kleinveld HA, Demacker PNM, Stalenhoef AFH: Comparative study on the effect of low-dose vitamin E and probucol on the susceptibility of LDL to oxidations and the progression of atherosclerosis in Watanabe Heritable Hyperlipidemic Rabbits. Arterioscler Thromb 1994;14:1386-1391.
17. Jacques PF, Hartz SC, McGandy RB, Jacob RA, Russell RM: Ascorbic acid, HDL and total plasma cholesterol in the elderly. J Am Coll Nutr 1987;6:169-174.
18. Dallal GE, Choi E, Jacques P, Schaefer EJ, Jacob RA: Ascorbic acid, HDL cholesterol and apolipoprotein A-I in an elderly Chinese population in Boston. J Am Coll Nutr 1989;8:69-74.
19. Burr ML, Bates CJ, Milbank JE, Yarnell JMC: The relationship between plasma ascorbate and lipid concentrations in fasting men. Hum Nutr Clin Nutr 1982;36C:135-139.
20. Greco AM, LaRocca L: Correlation between chronic hypovitaminosis C in old age and plasma levels of cholesterol and triglycerides. Int J Vitam Nutr Res 1982;23(suppl):129-136.
21. Gey KF: On the antioxidant hypothesis with regard to atherosclerosis. Bibl Nutr Dieta 1986; 37:53-91.
22. Yagi K: Lipid peroxides and human disease. Chem Phys Lipids 1987;45:337-351.
23. Katsouyanni K, Skalkidis Y, Petridou E, Polychronopoulou-Trichopoulou A, Willet W, Trichopoulos D: Diet and peripheral arterial occlusive disease: The role of poly-, mono-, and saturated fatty acids. Am J Epidemiol 1991; 133:24-31.
24. Machtey I, Syrkis I, Fried M: Studies of blood ascorbic acid levels in acute myocardial infarction. Clin Chim Acta 1975;62:149-151.
25. Luc G, Fruchart J-C: Oxidation of lipoproteins and atherosclerosis. Am J Clin Nutr 1991;53: 206s-209s.
26. Miki M, Motoyama T, Mino M: Synergistic inhibition of oxidation in RBC ghosts by vitamins C and E. Ann NY Acad Sci 1989;570: 474-477.
27. Van Den Berg JJM, Roelofsen B, Op Den Kamp JAF, Van Deenen LLM: Cooperative protection by vitamin E and C of human erythrocyte membranes against peroxidations. Ann NY Acad Sci 1989;570:527-529.
28. Nunes GL, Sgoutas DS, Redden RA, Sigman SR, Gravanis MB, King III SB, Berk BC: Combination of vitamins C and E alters the response to coronary balloon injury in the pigs. Arterioscler Thromb Vase Biol 1995;15:156-165.
29. Riemersma RA, Wood DA, Macintyre CCA, Elton RA, Gey KF, Oliver MF: Risk of angina pectoris and plasma concentrations of vitamins A, C, E and carotene. Lancet 1991;337:1-5.
30. Verlangieri AJ, Bush MJ: Effects of d-alpha-tocopherol supplementation on experimentally induced primate atherosclerosis. J Am Coll Nutr 1992;11:131-138.
31. DeMaio SJ, King SB III, Lembo NJ, Roubin GS, Hearn JA, Bhagavan HN, Sgoutas DS: Vitamin E supplementation, plasma lipids and incidence of restenosis after percutaneous transluminal coronary angioplasty (PTCA). J Am Coll Nutr 1992;11:68-73.
32. Rimm EB, Stampfer MJ, Ascherio A, Giovannucci E, Colditz GA, Willett WC: Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med 1993;328:1450-1456.
33. Stampfer MJ, Hennekens CH, Manson JE, Colditz GA, Rosner B, Willett WC: Vitamin E consumption and the risk of coronary disease in women. N Engl J Med 1993;328:1444-1449.
34. Keaney JF Jr, Gaziano JM, Xu A, Frei B, Curran-Celentano J, Shwaery GT, Loscalzo J, Vita JA: Dietary antioxidants preserve endothelium-dependent vessel relaxation in cholesterol-fed rabbits. Proc Natl Acad Sci USA 1993; 90:11880-11884.
35. Parker RA, Sabrah T, Cap M, Gill BT: Relation of vascular oxidative stress, alpha-tocopherol and hypercholesterolemia to early atherosclerosis in hamsters. Arterioscler Thromb Vasc Biol 1995;15:349-359.
36. Lafont AM, Chai YC, Cornhill JF, Whitlow PL, Howe PH, Chisolm GM: Effect of alpha-tocopherol on restenosis after angioplasty in a model of experimental atherosclerosis. J Clin Invest 1995;95:1018-1025.
37. Hennekens CH, Buring JE, Manson JE, Stampfer M, Rosner B. Cook NR, et al: Lack of effect of long-term supplementation with beta-carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med 1996;334:1145-1149.
38. Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, Glass A, et al: Effects of a combination of beta-carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med 1996;334:1150-1155.
39. Sokoloff B, Hori M, Saelhof C, McConnell B, Imai T: Effect of ascorbic acid on certain blood fat metabolism factors in animals and man. J Nutr 1967;91:107-118.
40. Prasad K, Kalra J: Oxygen free radicals and hypercholesterolemic atherosclerosis: Effect of vitamin E. Am Heart J 1993;125:958-973.
41. Keaney JF Jr, Gaziano JM, Xu A, Frei B, Curran-Celentano J, Shwaery GT, Loscalzo J, Vita JA: Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits. J Clin Invest 1994;93:844-851.
42. Fruebis J, Carew TE, Palinski W: Effect of vitamin E on atherosclerosis in LDL receptor-deficient rabbits. Atherosclerosis 1995;117:217-224.
43. Morel DW, da la Margarita LM, Friday KE: Treatment of cholesterol-fed rabbits with dietary vitamins E and C inhibits lipoprotein oxidation but not development of atherosclerosis. J Nutr 1994;124:2123-2130.
44. Raal FJ, Areias AJ, Pilcher GJ, Joffe BI, Seftel HC: Lack of effect of high dose vitamin E on xanthoma regression in homozygous family hypercholesterolaemia. Atherosclerosis 1994; 107:213-219.