Dendritic cells cultured from mononuclear cells and CD34 cells in myeloma do not harbour human herpesvirus 8

British Journal of Haematology

Volumn 100, Issue 4, 1998, Pages 793-796

  Cull, G M ^a,b   Timms, J M ^a   Haynes, A P ^a   Russell, N H ^a   Irving, W L ^a   Ball, J K ^a   Thomson, B J ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b NOTTINGHAM CITY HOSPITAL   (United Kingdom)

Author keywords

Dendritic cells; Human herpesvirus 8; Immunotherapy; Myeloma

Indexed keywords

CD34 ANTIGEN; CYCLOPHOSPHAMIDE; DNA; GRANULOCYTE COLONY STIMULATING FACTOR;

ANTIGEN PRESENTING CELL; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; LEUKAPHERESIS; MONONUCLEAR CELL; MYELOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ANTIGENS, CD34; DENDRITIC CELLS; FLOW CYTOMETRY; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 8, HUMAN; HUMANS; MULTIPLE MYELOMA; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY;

EID: 0031881523     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00671.x     Document Type: Article

References (16)

1. Boshoff, C., Gao, S.J. & Healy, L.E. (1998) KSHV positive primary effusion lymphoma cells (PELs) lack adhesion molecules, Blood (in press).
2. Cesarman, E., Chang, Y., Moore, P.S., Said, J.W. & Knowles, D.M. (1995) Kaposi's sarcoma-associated herpesvirus-like DNA in AIDS-related body-cavity-based lymphomas. New England Journal of Medicine, 332, 1186-1191.
3. Chang, Y., Cesarman, E., Pessin, M., Lee, F., Culpepper, J., Knowles, D.M. & Moore, P.S. (1994) Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science, 266, 1865-1869.
4. + cells in multiple myeloma (MM) patients. Blood, 90, 86a.
5. Hsu, F.J., Benike, C., Fagnoni, F., Liles. T.M., Czerwinski, D., Taidi, B., Englman, E.G. & Levy. R. (1996) Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells. Nature Medicine, 2, 52-58.
6. Huang, Y.Q., Li, J.J., Kaplin, M.H., Poiesz, B., Katabira, E., Zhang, W.C., Feiner, D. & Friedman-Kien, A.E. (1995) Human herpesvirus-like nucleic acid in various forms of Kaposi's sarcoma. Lancet, 345, 759-761.
7. MacKenzie, J., Sheldon, J., Morgan, G., Cook, G., Schulz, T.F. & Jarrett, R.F. (1997) HHV-8 and multiple myeloma in the UK. Lancet, 350, 1144-1145.
8. Marcelin, A., Dupin, N., Bouscary, D., Bossi, P., Cacoub, P., Ravaud, P. & Calvez, V. (1997) HHV-8 and multiple myeloma in France. (Letter). Lancet, 350, 1144.
9. Reichardt, V., Okada, C., Benike, C., Long, G., Englman, E., Blume, K. & Levy, R. (1996) Idiotypic vaccination using dendritic cells for multiple myeloma patients after autologous peripheral blood stem cell transplantation. Blood, 88, (Suppl. 1). 481a.
10. Rettig, M.B., Ma, H.J., Vescio, R.A., Pold, M., Schiller, G., Belson, D., Savage, A., Nishikubo, C., Wu, C., Fraser, J., Said, J.W. & Berenson, J.R. (1997) Kaposi's sarcoma-associated herpesvirus infection of bone marrow dendritic cells from multiple myeloma patients. Science, 276, 1851-1854.
11. Romani, N., Gruner, S., Brang, D., Kampgen, E., Lenz, A., Trockenbacher, B., Konwalinka, G., Fritsch, P.O., Steinman, R.M. & Schuler, G. (1994) Proliferating dendritic cell progenitors in human blood. Journal of Experimental Medicine, 180, 83-93
12. Said, J.W., Rettig, M.R., Heppner, K., Vescio, R.A., Schiller, G., Ma, H.J., Belson, D., Savage, A., Shintaku, I.P., Koeffler, H.P., Asou, H., Pinkus, G., Pinkus, P., Schrage, M., Green, E. & Berenson, J.R. (1997) Localization of Kaposi's sarcoma-associated herpesvirus in bone marrow biopsy samples from patients with multiple myeloma. Blood, 90, 4278-4282.
13. Strobl, H., Bello-Fernandez, C., Riedl, E., Pickl, W.F., Majdic, O., Lyman, S.D. & Knapp, W. (1997) Flt3 ligand in cooperation with transforming growth factor-B1 potentiates in vitro development of Langerhans-type dendritic cells and allows single-cell dendritic cell cluster formation under serum-free conditions. Blood, 90, 1425-1434.
14. Tisdale, J.F., Stewart, A.K., Dickstein, B., Dube, I.D., Cappe, D., Dunbar, C.E. & Brown, K.E. (1997) Human herpesvirus 8 in patients with multiple myeloma. Blood, 90, 588a.
15. Van Schooten, W., Strang, G. & Palathumpat, V. (1997) Biological properties of dendritic cells: implications for their use in the treatment of cancer. Molecular Medicine Today, 3, 254-260.
16. Vescio, R., Wu, C., Rettig, M., Stewart, A., Ballester, O., Noga, S., Rugo, H., Freytes, C., Stadtmauer, E., Kogut, N., Tarantolo, S., Stiff, P., Pinero, L., Dalton, W., Ho, A., Schiller, G., Benyunes, M., Jacobs, C., Dispersio, J., Anderson, K. & Berenson, J. (1997) The detection of KSHV is increased by mobilisation chemotherapy and reduced in autografts by CD34-selection. Blood, 90, 565a.