Limited genetic control of specific IgE responses to rye grass pollen allergens in Australian twins

Clinical and Experimental Allergy

Volumn 28, Issue 3, 1998, Pages 322-331

  Sluyter, R ^a   Tovey, E R ^a   Duffy, D L ^b   Britton, W J ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Atopy; IgE repertoire; Immunoblotting; Ryegrass pollen allergy; Twins

Indexed keywords

ALLERGEN; IMMUNOGLOBULIN E;

ALLERGY; ARTICLE; AUSTRALIA; DIZYGOTIC TWINS; ENVIRONMENTAL FACTOR; GENETIC REGULATION; GRASS POLLEN; HUMAN; IMMUNOBLOTTING; MAJOR CLINICAL STUDY; MONOZYGOTIC TWINS; PRIORITY JOURNAL; TWINS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLERGENS; ANTIBODY SPECIFICITY; ANTIGEN-ANTIBODY REACTIONS; AUSTRALIA; BINDING SITES, ANTIBODY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HUMANS; IMMUNOBLOTTING; IMMUNOGLOBULIN E; LOLIUM; MALE; MIDDLE AGED; PLANT PROTEINS; POLLEN; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 0031881433     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.1998.00223.x     Document Type: Article

References (41)

1. Wilkinson J, Holgate ST. Candidate gene loci in asthmatic and allergic inflammation. Thorax 1996; 51:3-8.
2. Newman-Taylor A. Environmental determinants of asthma. Lancet 1995; 345:296-9.
3. Shirakawa T, Li AR, Dubowitz M et al. Association between atopy and variants of the beta subunit of the high-affinity immunoglobulin E receptor. Nat Genet 1994; 7:125-30.
4. Marsh DG, Neely JD, Breazeale DR et al. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 1994; 264: 1152-6.
5. van Herwerden L, Harrap SB, Wong ZYH et al. Linkage of high-affinity IgE receptor gene with bronchial hyperreactivity. even in the absence of atopy. Lancet 1995; 346:1262-5.
6. Postma DS, Bleecker ER, Amelung PJ et al. Genetic susceptibility to asthma - Bronchial hyperresponsiveness coinherited with a major gene for atopy. N Engl J Med 1995; 333:894-900.
7. Venugopal G, Yang M, Luo Z, Salo D, Cheang M, Mohapatra SS. Analysis of TcRvb8, Il4, and Ifg as genetic predisposition factors for atopic IgE response in a murine model. J Immunol 1995; 155:5463-70.
8. Wuthrich B, Baumann E, Fries R, Schnyder U. Total and specific IgE (RAST) in atopic twins. Clin Allergy 1981; 30:147-54.
9. Blumenthal MN, Bonini S. Immunogenetics of specific immune responses to allergens in twins and families. In: Marsh DG and Blumenthal MN, eds. Genetic and environmental factors in clinical allergy. Minneapolis: University of Minnesota Press, 1990:132-42.
10. Hanson B, McGue M, Roitman-Johnson B, Segal NL, Bouchard TJ, Blumenthal MN. Atopic disease and immunoglobulin E in twins reared apart and together. Am J Hum Genet 1991; 48:873-9.
11. Levine BB, Stember RH, Fotino M. Ragweed hayfever: Genetic control and linkage to HLA haplotypes. Science 1982; 178:1201-3.
12. Marsh DG. Immunogenetic and immunochemical factors determining immune responsiveness to allergens: Studies in unrelated subjects. In: Marsh DG and Blumenthal MN, eds. Genetic and environmental factors in clinical allergy. Minneapolis: University of Minnesota Press, 1990:97-123.
13. Tautz C, Pihs H-P, Thiele A et al. Association of class II sequences encoding DR1 and DQ5 specificites with hypersensitivity to chironomid allergen Chi t I. J Allergy Clin Immunol 1994; 93:918-25.
14. Young RP, Dekker JW, Wordsworth BP et al. HLA-DR and HLA-DP genotypes and immunoglobulin E responses to common major allergens. Clin Exp Allergy 1994; 24:431-9.
15. Matsushita S, Muto M, Suemura M, Saito Y, Sasazuki T. HLA-linked nonresponsiveness to Cryptomeria japonica pollen antigens. I. Nonresponsiveness is mediated by antigen-specific suppressor T cell. J Immunol 1987; 138:109-15.
16. Lympany P, Kemeny DM, Welsh KI, Lee TH. An HLA-associated nonresponsiveness to mellitin: a component of bee venom. J Allergy Clin Immunol 1990; 86:160-70.
17. Reid MJ, Nish WA, Whisman BA et al. HLA-DR4-associated nonresponsiveness to mountain cedar allergen. J Allergy Clin Immunol 1992; 89:593-8.
18. Moffatt MF, Hill MR, Cornelis F et al. Genetic linkage of T-cell receptor α/δ complex to specific IgE responses. Lancet 1994; 343:1597-1600.
19. Mohapatra SS, Mohapatra S, Yang M et al. Molecular basis of cross-reactivity among allergen-specific human T cells: T-cell receptor Vα gene usage and epitope structure. Immunology 1994; 81:15-20.
20. Ford SA, Baldo BA. A re-examination of ryegrass (Lolium perenne) pollen allergens. Int Arch Allergy Appl Immunol 1986; 81:193-203.
21. Duffy DL, Martin NG, Battistutta D, Hopper JL, Mathews JD. Genetics of asthma and hay fever in Australian Twins. Am Rev Respir Dis 1990; 142:1351-8.
22. Tovey ER, Sluyter R, Duffy DL, Britton WJ. Immunoblotting analysis of twin sets provides evidence for limited genetic control of specific IgE to house dust mite allergens. J Allergy Clin Immunol in press.
23. Tovey ER, Baldo BA. Standardization of Allergens: Qualitative definition of house dust mite extracts following electro-blotting and detection of components with antibody and lectin probes. Int Arch Allergy Appl Immunol 1984; 75:322-9.
24. Towbin H, Staehelin T, Gordan J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Nat Acad Sci USA 1979; 76:4350-4.
25. Marsh DG, Meyers DA, Bias WB. The epidemiology and genetics of atopic allergy. N Engl J Med 1981; 305:1551-9.
26. Ekramoddoullah AKM, Kisil FT, Sehon AK. Immunochemical characterization of u high molecular weight basic allergen (HMBA) of ryegrass (Loliuin perenne) pollen. Mol Immunol 1983; 20:465-73.
27. Matthiewsen F, Lowenstein H. Group V allergens in grass pollen. II. Investigation of group V allergens in pollens from 10 grasses. Clin Exp Allergy 1991; 21:309-20.
28. Ansari AA, Killoran EA, Marsh DG. An investigation of human immune responses to perennial ryegrass (Lolium perenne) pollen cytochrome c (Lol p X). J Allergy Clin Immunol 1987; 80:229-35.
29. Freidhoff LL, Erhlich-Kautzy EE, Meyers DA et al. Association of HLA-DR3 with human response to Lol p I and II allergens in allergic subjects. Tissue Antigens 1988; 31:211-9.
30. Speigelberg HL, Beck L, Stevenson DD, Ishioka GY. Recognition of T cell epitopes and lymphokine secretion by rye grass allergen Lolium perenne I-specific human T cell clones. J Immunol 1994; 152:4706-11.
31. Ansari AA, Freidhoff LR, Meyers DA, Bias WB, Marsh DG. Human immune responsiveness to Lolium perenne pollen allergen Lol p III (Rye III) is associated with HLA-DR3 and HLA-DR5. Hum Immunol 1989; 25:59-71.
32. Valenta R, Steinberger P, Duchene M, Kraft D. Immunological and structural similarities among allergens: Prerequisite for a specific and component-based therapy of allergy. Immunol Cell Biol 1996; 74:187-194.
33. Pham NH, Baldo BA. Allergenic relationship between taxonomically diverse pollens. Clin Exp Allergy 1995; 25:599-606.
34. Mohapatra SS. Determinant spreading: implications in allergic disorders. Immunol Today 1994; 15:596-7.
35. Howlett BJ, Hill DJ, Knox RB. Cross-reactivity between Acacia (wattle) and rye grass pollen allergens. Clin Allergy 1982; 12:259-68.
36. Donovan GR, Baldo BA. Crossreactivity of IgE antibodies from the sera of subjects allergic to both ryegrass pollen and wheat endosperm proteins: evidence for common allergenic determinants. Clin Exp Allergy 1990; 501-9.
37. Smith PM, Ong EK, Knox RB, Singh MB. Immunological relationships among group I and group V allergens from among grass pollens. Mol Immunol 1994; 31:491-8.
38. Loveridge JA, Rosenberg WMC, Kirkwood TBL, Bell JI. The genetic contribution to human T-cell receptor repertoire. Immunology 1991; 74:246-50.
39. Hawes GE, Struyk L, van den Elsen PJ. Differential usage of T cell receptor V gene segments in CD4+ and CD8+ subjects of T lymphocytes in monozygotic twins. J Immunol 1993; 150:2033-45.
40. Ebner C, Schenk S, Najafian N et al. Nonallergic individuals recognize the same T cell epitopes of Bet pv 1, the major birch pollen allergen, as atopic patients. J Immunol 1995; 154: 1932-40.
41. Schenk S, Breiteneder H, Susani M et al. T-cell epitopes of PhI p 1, major pollen allergen of timothy grass (Phleum pratense): Evidence for crossreacting and non-crossreacting T-cell epitopes within grass group I allergens. J Allergy Clin Immunol 1995; 96:986-96.