-
1
-
-
0025753852
-
The molecular pathology of Alzheimer's disease
-
Selkoe DJ. The molecular pathology of Alzheimer's disease. Neuron 1991;6:481-487.
-
(1991)
Neuron
, vol.6
, pp. 481-487
-
-
Selkoe, D.J.1
-
2
-
-
0028243033
-
Cellular and molecular biology of Alzheimer's disease and animal models
-
Price DL, Sisodia SS. Cellular and molecular biology of Alzheimer's disease and animal models. Ann Rev Med 1994;45: 435-446.
-
(1994)
Ann Rev Med
, vol.45
, pp. 435-446
-
-
Price, D.L.1
Sisodia, S.S.2
-
3
-
-
0029784838
-
Amyloid β-protein and the genetics of Alzheimer's disease
-
Selkoe DJ. Amyloid β-protein and the genetics of Alzheimer's disease. J Biol Chem 1996;27:18295-18298.
-
(1996)
J Biol Chem
, vol.27
, pp. 18295-18298
-
-
Selkoe, D.J.1
-
4
-
-
0029058571
-
Alzheimer neurofibrillary lesions: Molecular nature and potential roles of different components
-
Yen SH, Liu WK, Hall FL, Yan SD, Stern D, Dickson DW. Alzheimer neurofibrillary lesions: molecular nature and potential roles of different components. Neurobiol Aging 1995; 16:3:381-387.
-
(1995)
Neurobiol Aging
, vol.16
, Issue.3
, pp. 381-387
-
-
Yen, S.H.1
Liu, W.K.2
Hall, F.L.3
Yan, S.D.4
Stern, D.5
Dickson, D.W.6
-
5
-
-
0028898888
-
Mechanisms of synaptic degeneration in Alzheimer's disease
-
Masliah E. Mechanisms of synaptic degeneration in Alzheimer's disease. Histol Histopathol 1995;10:509-519.
-
(1995)
Histol Histopathol
, vol.10
, pp. 509-519
-
-
Masliah, E.1
-
6
-
-
0029012611
-
The cortical neuritic dystrophy of Alzheimer's disease: Nature, significance, and possible pathogenesis
-
Larner AJ. The cortical neuritic dystrophy of Alzheimer's disease: nature, significance, and possible pathogenesis. Dementia 1995;6:218-224.
-
(1995)
Dementia
, vol.6
, pp. 218-224
-
-
Larner, A.J.1
-
7
-
-
0028103819
-
Inflammatory mechanisms in Alzheimer's disease: Implications for therapy
-
Aisen PS, Davis KL. Inflammatory mechanisms in Alzheimer's disease: implications for therapy. Am J Psychiatry 1994;151:1105-1113.
-
(1994)
Am J Psychiatry
, vol.151
, pp. 1105-1113
-
-
Aisen, P.S.1
Davis, K.L.2
-
10
-
-
0028334028
-
Estradiol and progesterone regulate neuronal structure and synaptic connectivity in adult as well as developing brain
-
McEwan BS, Woolley CS. Estradiol and progesterone regulate neuronal structure and synaptic connectivity in adult as well as developing brain. Exp Gerontol 1994;29:431-436.
-
(1994)
Exp Gerontol
, vol.29
, pp. 431-436
-
-
McEwan, B.S.1
Woolley, C.S.2
-
11
-
-
0018078940
-
Correlation of cholinergic abnormalities with senile plaques and mental scores in senile dementia
-
Perry EK, Tomlinson BE, Blesses G, et al. Correlation of cholinergic abnormalities with senile plaques and mental scores in senile dementia. BMJ 1978;2:1457-1459.
-
(1978)
BMJ
, vol.2
, pp. 1457-1459
-
-
Perry, E.K.1
Tomlinson, B.E.2
Blesses, G.3
-
12
-
-
0030976004
-
Cognitive enhancement therapy for Alzheimer's disease
-
Parnetti L, Senin U, Mecocci P. Cognitive enhancement therapy for Alzheimer's disease. Drugs 1997;53:752-768.
-
(1997)
Drugs
, vol.53
, pp. 752-768
-
-
Parnetti, L.1
Senin, U.2
Mecocci, P.3
-
14
-
-
0008941101
-
-
Rockville, MD: Dept of Health and Human Services, Public Health Service, Food and Drug Administration
-
Peripheral and Central Nervous System Drugs Advisory Committee Meeting, July 7, 1989. Rockville, MD: Dept of Health and Human Services, Public Health Service, Food and Drug Administration, 1989:227.
-
(1989)
Peripheral and Central Nervous System Drugs Advisory Committee Meeting, July 7, 1989
, pp. 227
-
-
-
15
-
-
0030958347
-
The Neuropsychiatric Inventory: Assessing psychopathology in dementia patients
-
Cummings JL. The Neuropsychiatric Inventory: assessing psychopathology in dementia patients. Neurology 1997;48(5 Suppl 6):S10-6.
-
(1997)
Neurology
, vol.48
, Issue.5 SUPPL. 6
-
-
Cummings, J.L.1
-
17
-
-
0020040238
-
A new rating scale for the staging of dementia
-
Hughs CD, Berg L, Danziger L, Coben LA, Martin RL. A new rating scale for the staging of dementia. Br J Psychiatry 1982;140:566-572.
-
(1982)
Br J Psychiatry
, vol.140
, pp. 566-572
-
-
Hughs, C.D.1
Berg, L.2
Danziger, L.3
Coben, L.A.4
Martin, R.L.5
-
18
-
-
0345467172
-
Measurement of quality-of-life changes in patients with Alzheimer's disease
-
DeJong R, Osterlund OW, Roy GW. Measurement of quality-of-life changes in patients with Alzheimer's disease. Clin Ther 1988;139:1136-1139.
-
(1988)
Clin Ther
, vol.139
, pp. 1136-1139
-
-
DeJong, R.1
Osterlund, O.W.2
Roy, G.W.3
-
19
-
-
0006037977
-
Assessment of functioning and ADL
-
Gauthier L, Gauthier S, Gelinas I, McIntyre M, Wood-Dauphinee S. Assessment of functioning and ADL [abstract]. Proc Sixth Cong Psychogeriatr Assoc 1993:9.
-
(1993)
Proc Sixth Cong Psychogeriatr Assoc
, pp. 9
-
-
Gauthier, L.1
Gauthier, S.2
Gelinas, I.3
McIntyre, M.4
Wood-Dauphinee, S.5
-
20
-
-
0025217385
-
Quantitative assessment of cortical synaptic density in Alzheimer's disease
-
Scheff SW, DeKosky ST, Price DA. Quantitative assessment of cortical synaptic density in Alzheimer's disease. Neurobiol Aging 1990;11:29-37.
-
(1990)
Neurobiol Aging
, vol.11
, pp. 29-37
-
-
Scheff, S.W.1
DeKosky, S.T.2
Price, D.A.3
-
21
-
-
0025987048
-
Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
-
Terry RD, Masliah E, Salmon DP, et al. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol 1991;30:572-580.
-
(1991)
Ann Neurol
, vol.30
, pp. 572-580
-
-
Terry, R.D.1
Masliah, E.2
Salmon, D.P.3
-
22
-
-
0023480629
-
Failure of long term high-dose lecithin to retard progression of early-onset Alzheimer's disease
-
Heyman A, Schmechel D, Wilkonson W, et al. Failure of long term high-dose lecithin to retard progression of early-onset Alzheimer's disease. J Neural Transm 1987;24(suppl):279-1286.
-
(1987)
J Neural Transm
, vol.24
, Issue.SUPPL.
, pp. 279-1286
-
-
Heyman, A.1
Schmechel, D.2
Wilkonson, W.3
-
23
-
-
0024806695
-
The role of nicotine receptors in the pathophysiology of Alzheimer's disease
-
Nordberg A, Nilsson-Hakansson L, Adem A, et al. The role of nicotine receptors in the pathophysiology of Alzheimer's disease. Prog Brain Res 1989;79:353-362.
-
(1989)
Prog Brain Res
, vol.79
, pp. 353-362
-
-
Nordberg, A.1
Nilsson-Hakansson, L.2
Adem, A.3
-
24
-
-
0021645917
-
3H]ACh release from mouse cerebral cortical synaptosomes
-
3H]ACh release from mouse cerebral cortical synaptosomes. J Neurochem 1984;43:1593-1598.
-
(1984)
J Neurochem
, vol.43
, pp. 1593-1598
-
-
Rowell, P.P.1
Winkler, D.L.2
-
25
-
-
0043037865
-
Long-term actions of nicotinic receptor stimulation in nucleus basalis lesioned rats: Blockade of transsynaptic cell loss
-
Nagatsu T, Fisher A, Yoshida M, eds. New York: Plenum Press
-
Sjak-Shie NN, Burks JN, Meyer EM. Long-term actions of nicotinic receptor stimulation in nucleus basalis lesioned rats: blockade of transsynaptic cell loss. In: Nagatsu T, Fisher A, Yoshida M, eds. Advances in behavioral biology. New York: Plenum Press, 1990:471-475.
-
(1990)
Advances in Behavioral Biology
, pp. 471-475
-
-
Sjak-Shie, N.N.1
Burks, J.N.2
Meyer, E.M.3
-
26
-
-
0001562835
-
Nicotine as a tool to characterize the role of the forebrain cholinergic projection system in cognition
-
Lippiello PM, Collins AC, Gray JA, Robinson JA, eds. New York: Raven Press
-
Hodges H, Sinden J, Turner JJ, Netto CA, Sowinski P, Gray JA. Nicotine as a tool to characterize the role of the forebrain cholinergic projection system in cognition. In: Lippiello PM, Collins AC, Gray JA, Robinson JA, eds. The biology of nicotine: current research issues. New York: Raven Press, 1992: 157-182.
-
(1992)
The Biology of Nicotine: Current Research Issues
, pp. 157-182
-
-
Hodges, H.1
Sinden, J.2
Turner, J.J.3
Netto, C.A.4
Sowinski, P.5
Gray, J.A.6
-
27
-
-
0025780198
-
Beneficial effects of nicotine administered before a delayed-matching-to-sample task in young and aged monkeys
-
Buccafusco JJ, Jackson WJ. Beneficial effects of nicotine administered before a delayed-matching-to-sample task in young and aged monkeys. Neurobiol Aging 1991;12:233-238.
-
(1991)
Neurobiol Aging
, vol.12
, pp. 233-238
-
-
Buccafusco, J.J.1
Jackson, W.J.2
-
28
-
-
0026649175
-
Nicotinic systems and cognitive function
-
Levin ED. Nicotinic systems and cognitive function. Psychopharmacology 1992;108:417-431.
-
(1992)
Psychopharmacology
, vol.108
, pp. 417-431
-
-
Levin, E.D.1
-
29
-
-
0029956783
-
Nicotine inhibits amyloid formation by the beta-peptide
-
Salomon AR, Marcinowski KJ, Friedland RP, Zagorski MG. Nicotine inhibits amyloid formation by the beta-peptide. Biochemistry 1996;35:42:13568-13578.
-
(1996)
Biochemistry
, vol.35
, Issue.42
, pp. 13568-13578
-
-
Salomon, A.R.1
Marcinowski, K.J.2
Friedland, R.P.3
Zagorski, M.G.4
-
30
-
-
0028365441
-
Smoking and Alzheimer's disease: A review of the epidemiological evidence
-
Lee PN. Smoking and Alzheimer's disease: a review of the epidemiological evidence. Neuroepidemiology 1994;13:131-144.
-
(1994)
Neuroepidemiology
, vol.13
, pp. 131-144
-
-
Lee, P.N.1
-
31
-
-
0029054285
-
Nicotine patches in Alzheimer's disease: Pilot study on learning, memory, and safety
-
Wilson AL, Langley LK, Monley J, et al. Nicotine patches in Alzheimer's disease: pilot study on learning, memory, and safety. Pharm Biochem Behav 1995;51:509-514.
-
(1995)
Pharm Biochem Behav
, vol.51
, pp. 509-514
-
-
Wilson, A.L.1
Langley, L.K.2
Monley, J.3
-
32
-
-
0030049572
-
The effects of nicotine in dermal plaster on cognitive function in patients with Alzheimer's disease
-
Snaedal J, Johannesson T, Jonsson JE, Gylfadottir G. The effects of nicotine in dermal plaster on cognitive function in patients with Alzheimer's disease. Dementia 1996;7:47-52.
-
(1996)
Dementia
, vol.7
, pp. 47-52
-
-
Snaedal, J.1
Johannesson, T.2
Jonsson, J.E.3
Gylfadottir, G.4
-
33
-
-
0026504115
-
Interaction of tetrahydroaminoacridine with acetylcholinesterases and butyrylcholinesterase
-
Berman HA, Leonard K. Interaction of tetrahydroaminoacridine with acetylcholinesterases and butyrylcholinesterase. Mol Pharmacol 1992;41:412-418.
-
(1992)
Mol Pharmacol
, vol.41
, pp. 412-418
-
-
Berman, H.A.1
Leonard, K.2
-
34
-
-
0029029759
-
Cholinesterase inhibitors proposed for treating dementia in Alzheimer's disease: Selectivity toward human brain acetylcholinesterase compared with butyrylcholinesterase
-
Pacheco G, Palacios-Esquivel R, Moss DE. Cholinesterase inhibitors proposed for treating dementia in Alzheimer's disease: selectivity toward human brain acetylcholinesterase compared with butyrylcholinesterase. J Pharmacol Exp Ther 1995;274:767-770.
-
(1995)
J Pharmacol Exp Ther
, vol.274
, pp. 767-770
-
-
Pacheco, G.1
Palacios-Esquivel, R.2
Moss, D.E.3
-
35
-
-
0027973241
-
Butyrylcholinesterase reactivity differentiates the amyloid plaques of aging from those of dementia
-
Mesulam MM, Geula C. Butyrylcholinesterase reactivity differentiates the amyloid plaques of aging from those of dementia. Ann Neurol 1994;36:722-727.
-
(1994)
Ann Neurol
, vol.36
, pp. 722-727
-
-
Mesulam, M.M.1
Geula, C.2
-
36
-
-
0022899577
-
Oral tetra hydroaminoacridine in long-term treatment of senile dementia, Alzheimer type
-
Summers WK, Majovski LV, Marsh GM, Tachiki K, Kling A. Oral tetra hydroaminoacridine in long-term treatment of senile dementia, Alzheimer type. N Engl J Med 1986;315: 1241-1245.
-
(1986)
N Engl J Med
, vol.315
, pp. 1241-1245
-
-
Summers, W.K.1
Majovski, L.V.2
Marsh, G.M.3
Tachiki, K.4
Kling, A.5
-
37
-
-
0026756286
-
A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease
-
Davis KL, Thai LJ, Gamzu ER, et al. A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease. N Engl J Med 1992;327:1253-1259.
-
(1992)
N Engl J Med
, vol.327
, pp. 1253-1259
-
-
Davis, K.L.1
Thai, L.J.2
Gamzu, E.R.3
-
38
-
-
0026792979
-
A controlled trial of tacrine in Alzheimer's disease
-
Farlow MR, Gracon SI, Hershey LA, Lewis KW, Sadowsky CH, Dolan-Ureno J, for the Tacrine Study Group. A controlled trial of tacrine in Alzheimer's disease. JAMA 1992; 268:2523-2529.
-
(1992)
JAMA
, vol.268
, pp. 2523-2529
-
-
Farlow, M.R.1
Gracon, S.I.2
Hershey, L.A.3
Lewis, K.W.4
Ch, S.5
Dolan-Ureno, J.6
-
39
-
-
0025312142
-
Tetrahydroaminoacridine-lecithin combination treatment in patients with intermediate-stage Alzheimer's disease
-
Gauthier S, Bouchard R, Lamontagne A, et al. Tetrahydroaminoacridine-lecithin combination treatment in patients with intermediate-stage Alzheimer's disease. N Engl J Med 1990;322:1272-1276.
-
(1990)
N Engl J Med
, vol.322
, pp. 1272-1276
-
-
Gauthier, S.1
Bouchard, R.2
Lamontagne, A.3
-
40
-
-
0028270519
-
A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease
-
Knapp MJ, Knopman DS, Solomon PR, Pendlebury WW, Davis CS, Gracon SI, for the Tacrine Study Group. A 30-week randomized controlled trial of high-dose tacrine in patients with Alzheimer's disease. JAMA 1993;271:985-991.
-
(1993)
JAMA
, vol.271
, pp. 985-991
-
-
Knapp, M.J.1
Knopman, D.S.2
Solomon, P.R.3
Pendlebury, W.W.4
Davis, C.S.5
Gracon, S.I.6
-
41
-
-
0000557157
-
E2020: The pharmacology of a piperidine cholinesterase inhibitor
-
Becker R, Giacobini E, eds. Boston: Birkhauser
-
Rogers SL, Yaminishi Y, Yamatsu K. E2020: the pharmacology of a piperidine cholinesterase inhibitor. In: Becker R, Giacobini E, eds. Cholinergic basis for Alzheimer therapy. Boston: Birkhauser, 1991;314-320.
-
(1991)
Cholinergic Basis for Alzheimer Therapy
, pp. 314-320
-
-
Rogers, S.L.1
Yaminishi, Y.2
Yamatsu, K.3
-
42
-
-
0344173387
-
-
Donepezil package insert
-
Donepezil package insert.
-
-
-
-
43
-
-
0031883716
-
A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
-
Rogers SL, Farlow MR, Mohs R, Friedhoff LT, and the Donepezil Study Group. A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease. Neurology 1998;50:136-145.
-
(1998)
Neurology
, vol.50
, pp. 136-145
-
-
Rogers, S.L.1
Farlow, M.R.2
Mohs, R.3
Friedhoff, L.T.4
-
44
-
-
0029766994
-
Efficacy and safety results of the early phase studies with exelon (ENA-713) in Alzheimer's disease: An overview
-
Anand R, Gharabawi G, Enz A. Efficacy and safety results of the early phase studies with exelon (ENA-713) in Alzheimer's disease: an overview. J Drug Dev Clin Pract 1996;8: 109-116.
-
(1996)
J Drug Dev Clin Pract
, vol.8
, pp. 109-116
-
-
Anand, R.1
Gharabawi, G.2
Enz, A.3
-
45
-
-
0344605084
-
The efficacy and safety of ENA-713 in patients with mild to moderately severe Alzheimer's disease
-
April
-
Corey-Bloom J. The efficacy and safety of ENA-713 in patients with mild to moderately severe Alzheimer's disease [abstract]. J Am Geriatr Soc 1998;April.
-
(1998)
J Am Geriatr Soc
-
-
Corey-Bloom, J.1
-
46
-
-
0006661537
-
Metrifonate: Potential therapy for Alzheimer's disease
-
Morris J, Cyrus P, Orazem J, Mas J, Bieber F, Gulanski B. Metrifonate: potential therapy for Alzheimer's disease [abstract]. Neurology 1997;48:1730.
-
(1997)
Neurology
, vol.48
, pp. 1730
-
-
Morris, J.1
Cyrus, P.2
Orazem, J.3
Mas, J.4
Bieber, F.5
Gulanski, B.6
-
47
-
-
0025272542
-
Effects of metrifonate, a long-acting cholinesterase inhibitor, in Alzheimer disease: Report of an open trial
-
Becker RE, Colliver J, Elble R, et al. Effects of metrifonate, a long-acting cholinesterase inhibitor, in Alzheimer disease: report of an open trial. Drug Dev Res 1990;19:425-434.
-
(1990)
Drug Dev Res
, vol.19
, pp. 425-434
-
-
Becker, R.E.1
Colliver, J.2
Elble, R.3
-
48
-
-
0031896251
-
Metrifonate: Overview of safety and efficacy
-
Cummings J. Metrifonate: overview of safety and efficacy. Pharmacotherapy 1998;18:43-46.
-
(1998)
Pharmacotherapy
, vol.18
, pp. 43-46
-
-
Cummings, J.1
-
49
-
-
0029792078
-
Double blind placebo control study of metrifonate, an acetylcholinesterase inhibitor of Alzheimer's disease
-
Becker RE, Colliver JA, Markwell SJ, et al. Double blind placebo control study of metrifonate, an acetylcholinesterase inhibitor of Alzheimer's disease. Alzheimers Dis Assoc Disord 1996;10:124-131.
-
(1996)
Alzheimers Dis Assoc Disord
, vol.10
, pp. 124-131
-
-
Becker, R.E.1
Colliver, J.A.2
Markwell, S.J.3
-
50
-
-
0028197477
-
Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines
-
Lahiri DK, Lewis S, Farlow MR. Tacrine alters the secretion of the beta-amyloid precursor protein in cell lines. J Neurosci Res 1994;37:1-11.
-
(1994)
J Neurosci Res
, vol.37
, pp. 1-11
-
-
Lahiri, D.K.1
Lewis, S.2
Farlow, M.R.3
-
51
-
-
0030035653
-
Long-term tacrine (Cognex) treatment: Effects on nursing home placement and mortality
-
Knopman D, Schneider L, Davis K, et al. Long-term tacrine (Cognex) treatment: effects on nursing home placement and mortality. Neurology 1996;47:166-177.
-
(1996)
Neurology
, vol.47
, pp. 166-177
-
-
Knopman, D.1
Schneider, L.2
Davis, K.3
-
52
-
-
0028924664
-
Rapid communication: Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease
-
Flynn DD, Ferrari-DiLeo G, Mash DC, Levey AI. Rapid communication: differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease. J Neurochem 1995;64:1888-1891.
-
(1995)
J Neurochem
, vol.64
, pp. 1888-1891
-
-
Flynn, D.D.1
Ferrari-DiLeo, G.2
Mash, D.C.3
Levey, A.I.4
-
53
-
-
0025644484
-
Cholinergic receptors in human brain: Effects of aging and Alzheimer's disease
-
Giacobini E. Cholinergic receptors in human brain: effects of aging and Alzheimer's disease. J Neurochem Res 1990;27: 548-560.
-
(1990)
J Neurochem Res
, vol.27
, pp. 548-560
-
-
Giacobini, E.1
-
54
-
-
0025943814
-
Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies
-
Levey AI, Kitt CA, Simonds WF, Price DL, Brann MR. Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies. J Neurosci 1991;11:3218-3225.
-
(1991)
J Neurosci
, vol.11
, pp. 3218-3225
-
-
Levey, A.I.1
Kitt, C.A.2
Simonds, W.F.3
Price, D.L.4
Brann, M.R.5
-
55
-
-
0026476297
-
Release of Alzheimer's amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
-
Nitsch RM, Slack BE, Wurtman RJ, Growdon JH. Release of Alzheimer's amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science 1992; 258:304-307.
-
(1992)
Science
, vol.258
, pp. 304-307
-
-
Nitsch, R.M.1
Slack, B.E.2
Wurtman, R.J.3
Growdon, J.H.4
-
56
-
-
0029166330
-
The muscarinic M1 agonist xanomeline increases soluble amyloid precursor protein release from Chinese hamster ovary-m1 cells
-
DeLapp NW, Eckols K, Bymaster FP, Mitch CH, Shannon HE, Ward JS. The muscarinic M1 agonist xanomeline increases soluble amyloid precursor protein release from Chinese hamster ovary-m1 cells. Life Sci 1995;57:1183-1190.
-
(1995)
Life Sci
, vol.57
, pp. 1183-1190
-
-
DeLapp, N.W.1
Eckols, K.2
Bymaster, F.P.3
Mitch, C.H.4
Shannon, H.E.5
Ward, J.S.6
-
57
-
-
0030902127
-
Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease
-
Bodick NC, Offen WW, Levey AI, et al. Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease. Arch Neurol 1997;54:465-473.
-
(1997)
Arch Neurol
, vol.54
, pp. 465-473
-
-
Bodick, N.C.1
Offen, W.W.2
Levey, A.I.3
-
58
-
-
0025790342
-
Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease
-
Smith CD, Carney JM, Starke-Reed PE, et al. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. Proc Natl Acad Sci USA 1991;88: 10540-10543.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 10540-10543
-
-
Smith, C.D.1
Carney, J.M.2
Starke-Reed, P.E.3
-
59
-
-
0029982815
-
Oxidative damage in Alzheimer's
-
Smith MA, Perry G, Richey PL, et al. Oxidative damage in Alzheimer's. Nature 1996;382:120-121.
-
(1996)
Nature
, vol.382
, pp. 120-121
-
-
Smith, M.A.1
Perry, G.2
Richey, P.L.3
-
60
-
-
0030967165
-
A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease
-
Sano M, Ernesto C, Thomas RG, et al; for the members of Alzheimer's Disease Cooperative Study. A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's disease. N Engl J Med 1997;336:1216-1222.
-
(1997)
N Engl J Med
, vol.336
, pp. 1216-1222
-
-
Sano, M.1
Ernesto, C.2
Thomas, R.G.3
-
61
-
-
0028819489
-
Estradiol enhances brain glucose uptake in ovariectomized rats
-
Bishop J, Simplins JW. Estradiol enhances brain glucose uptake in ovariectomized rats. Brain Res Cull 1995;36:315-320.
-
(1995)
Brain Res Cull
, vol.36
, pp. 315-320
-
-
Bishop, J.1
Simplins, J.W.2
-
62
-
-
0026722831
-
Role of estrogens in peripheral and cerebral glucose utilization
-
Bishop J, Simpkins JW. Role of estrogens in peripheral and cerebral glucose utilization. Rev Neurosci 1992;3:121-137.
-
(1992)
Rev Neurosci
, vol.3
, pp. 121-137
-
-
Bishop, J.1
Simpkins, J.W.2
-
63
-
-
0026047799
-
Estrogen-enhanced neurite growth: Evidence for a selective induction of tau and stable microtubules
-
Ferreira A, Caceres A. Estrogen-enhanced neurite growth: evidence for a selective induction of tau and stable microtubules. J Neurosci 1991;11:392-400.
-
(1991)
J Neurosci
, vol.11
, pp. 392-400
-
-
Ferreira, A.1
Caceres, A.2
-
64
-
-
0026714746
-
Time lapse study of neurite growth in hypothalamic dissociated neurons in culture: Sex differences and estrogen effects
-
Diaz H, Lorenzo A, Carrer HF, Caceres A. Time lapse study of neurite growth in hypothalamic dissociated neurons in culture: sex differences and estrogen effects. J Neurosci Res 1992;33:266-281.
-
(1992)
J Neurosci Res
, vol.33
, pp. 266-281
-
-
Diaz, H.1
Lorenzo, A.2
Carrer, H.F.3
Caceres, A.4
-
65
-
-
0028596087
-
Sex hormone modulation of neural development in vitro
-
Lustig RH. Sex hormone modulation of neural development in vitro. Horm Behav 1994;28:383-395.
-
(1994)
Horm Behav
, vol.28
, pp. 383-395
-
-
Lustig, R.H.1
-
67
-
-
0021861330
-
Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats
-
Luine V. Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats. Exp Neurol 1985;89:484-490.
-
(1985)
Exp Neurol
, vol.89
, pp. 484-490
-
-
Luine, V.1
-
68
-
-
0023935799
-
Effects of estradiol and dexamethasone on choline acetyltransferase activity in various rat brain regions
-
Kaufman H, Vadasz C, Lajtha A. Effects of estradiol and dexamethasone on choline acetyltransferase activity in various rat brain regions. Brain Res 1988;453:389-392.
-
(1988)
Brain Res
, vol.453
, pp. 389-392
-
-
Kaufman, H.1
Vadasz, C.2
Lajtha, A.3
-
69
-
-
0028913357
-
Hormonal status affects the reactivity of the cerebral vasculature
-
Belfort MA, Saade GR, Snabes M, et al. Hormonal status affects the reactivity of the cerebral vasculature. Am J Obstet Gynecol 1995;172:1273-1278.
-
(1995)
Am J Obstet Gynecol
, vol.172
, pp. 1273-1278
-
-
Belfort, M.A.1
Saade, G.R.2
Snabes, M.3
-
70
-
-
84937358210
-
Estrogen increases cerebral and cerebellar blood flows in postmenopausal women
-
Ohkura T, Teshima Y, Isse K, et al. Estrogen increases cerebral and cerebellar blood flows in postmenopausal women. Menopause 1995;2:13-18.
-
(1995)
Menopause
, vol.2
, pp. 13-18
-
-
Ohkura, T.1
Teshima, Y.2
Isse, K.3
-
71
-
-
0026341955
-
Effects of estrogen replacement therapy on cerebral perfusion and cognition among postmenopausal women
-
Funk JL, Mortel KF, Meyer JS. Effects of estrogen replacement therapy on cerebral perfusion and cognition among postmenopausal women. Dementia 1991;2:268-272.
-
(1991)
Dementia
, vol.2
, pp. 268-272
-
-
Funk, J.L.1
Mortel, K.F.2
Meyer, J.S.3
-
72
-
-
0028342424
-
Estrogen regulates metabolism of Alzheimer amyloid beta-precursor protein
-
Jaffe AB, Toran-Allerand CD, Greengard P, Gandy SE. Estrogen regulates metabolism of Alzheimer amyloid beta-precursor protein. J Biol Chem 1994;269:13065-13068.
-
(1994)
J Biol Chem
, vol.269
, pp. 13065-13068
-
-
Jaffe, A.B.1
Toran-Allerand, C.D.2
Greengard, P.3
Gandy, S.E.4
-
73
-
-
0029844969
-
Estrogen replacement therapy and risk of Alzheimer disease
-
Paganini-Hill A, Henderson VW. Estrogen replacement therapy and risk of Alzheimer disease. Arch Intern Med 1996; 156:2213-2217.
-
(1996)
Arch Intern Med
, vol.156
, pp. 2213-2217
-
-
Paganini-Hill, A.1
Henderson, V.W.2
-
74
-
-
0000910292
-
A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease in the Baltimore longitudinal study of aging
-
Morrison A, Resnick S, Corrada M, Zonderman A, Kawas C. A prospective study of estrogen replacement therapy and the risk of developing Alzheimer's disease in the Baltimore longitudinal study of aging [abstract]. Neurology 1996;46(suppl 2):A435-436.
-
(1996)
Neurology
, vol.46
, Issue.2 SUPPL.
-
-
Morrison, A.1
Resnick, S.2
Corrada, M.3
Zonderman, A.4
Kawas, C.5
-
75
-
-
0030591669
-
Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease
-
Tang M-X, Jacobs D, Stern Y, et al. Effect of oestrogen during menopause on risk and age at onset of Alzheimer's disease. Lancet 1996;348:429-432.
-
(1996)
Lancet
, vol.348
, pp. 429-432
-
-
Tang, M.-X.1
Jacobs, D.2
Stern, Y.3
-
76
-
-
0029091851
-
Lack of postmenopausal estrogen replacement therapy and the risk of dementia
-
Mortel KF, Meyer JS. Lack of postmenopausal estrogen replacement therapy and the risk of dementia. J Neuropsychiatry Clin Neurosci 1995;7:334-337.
-
(1995)
J Neuropsychiatry Clin Neurosci
, vol.7
, pp. 334-337
-
-
Mortel, K.F.1
Meyer, J.S.2
-
77
-
-
0000220959
-
Immunological and endocrine conditions in an Alzheimer's disease case-control study
-
Lerner A, Cole R, Debanne S, et al. Immunological and endocrine conditions in an Alzheimer's disease case-control study [abstract]. Neuroepidemiology 1995;14:307.
-
(1995)
Neuroepidemiology
, vol.14
, pp. 307
-
-
Lerner, A.1
Cole, R.2
Debanne, S.3
-
78
-
-
0002266183
-
The role of estrogen deficiency in the aging central nervous system
-
Lobo RA, ed. New York: Raven Press
-
Birge SJ. The role of estrogen deficiency in the aging central nervous system. In: Lobo RA, ed. Treatment of postmenopausal women: basic and clinical aspects. New York: Raven Press, 1994:153-157.
-
(1994)
Treatment of Postmenopausal Women: Basic and Clinical Aspects
, pp. 153-157
-
-
Birge, S.J.1
-
79
-
-
0028086440
-
Estrogen replacement therapy in older women: Comparison between Alzheimer's disease cases and nondemented control subjects
-
Henderson VW, Paganini-Hill A, Emanuel CK, Dunn ME, Buckwalter JG. Estrogen replacement therapy in older women: comparison between Alzheimer's disease cases and nondemented control subjects. Arch Neurol 1994;51:896-900.
-
(1994)
Arch Neurol
, vol.51
, pp. 896-900
-
-
Henderson, V.W.1
Paganini-Hill, A.2
Emanuel, C.K.3
Dunn, M.E.4
Buckwalter, J.G.5
-
80
-
-
0022525677
-
Observations in a preliminary open trial of estradiol therapy for senile dementia (Alzheimer's type)
-
Fillet H, Weinreb H, Cholst I, et al. Observations in a preliminary open trial of estradiol therapy for senile dementia (Alzheimer's type). Psychoneuroendocrinology 1986;11:337-334.
-
(1986)
Psychoneuroendocrinology
, vol.11
, pp. 337-1334
-
-
Fillet, H.1
Weinreb, H.2
Cholst, I.3
-
81
-
-
20244371008
-
In vivo effects by estrone sulfate on the central nervous system-senile dementia (Alzheimer's type)
-
Honjo H, Ogino Y, Naitoh K, et al. In vivo effects by estrone sulfate on the central nervous system-senile dementia (Alzheimer's type). J Steroid Biochem Mol Biol 1989;34:521-525.
-
(1989)
J Steroid Biochem Mol Biol
, vol.34
, pp. 521-525
-
-
Honjo, H.1
Ogino, Y.2
Naitoh, K.3
-
82
-
-
0030942683
-
The role of estrogen in the treatment of Alzheimer's disease
-
Birge SJ. The role of estrogen in the treatment of Alzheimer's disease. Neurology 1997;48(suppl 7):S36-41.
-
(1997)
Neurology
, vol.48
, Issue.7 SUPPL.
-
-
Birge, S.J.1
-
83
-
-
0029886801
-
Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease
-
Schneider LS, Farlow MR, Henderson VW, Pogoda JM. Effects of estrogen replacement therapy on response to tacrine in patients with Alzheimer's disease. Neurology 1996;46: 1580-1584.
-
(1996)
Neurology
, vol.46
, pp. 1580-1584
-
-
Schneider, L.S.1
Farlow, M.R.2
Henderson, V.W.3
Pogoda, J.M.4
-
84
-
-
0025763298
-
Interleukin-6 and alpha-2-macroglobulin indicate an acute phase response in Alzheimer's disease cortices
-
Bauer J, Strauss S, Schreiter-Gasser U. Interleukin-6 and alpha-2-macroglobulin indicate an acute phase response in Alzheimer's disease cortices. FEBS Lett 1991;285:111-114.
-
(1991)
FEBS Lett
, vol.285
, pp. 111-114
-
-
Bauer, J.1
Strauss, S.2
Schreiter-Gasser, U.3
-
85
-
-
0026783493
-
Distribution pattern and functional state of complement proteins and α1-antichymotrypsin in cerebral β/A4 deposits in Alzheimer's disease
-
Eikelenboom P, Hack CE, Kamphorst W, Rozemuller JM. Distribution pattern and functional state of complement proteins and α1-antichymotrypsin in cerebral β/A4 deposits in Alzheimer's disease. Res Immunol 1992;143:617-620.
-
(1992)
Res Immunol
, vol.143
, pp. 617-620
-
-
Eikelenboom, P.1
Hack, C.E.2
Kamphorst, W.3
Rozemuller, J.M.4
-
86
-
-
0021262101
-
Immuno-electron-microscopic localization of complements in amyloid fibrils of senile plaques
-
Berl
-
Ishii T, Haga S. Immuno-electron-microscopic localization of complements in amyloid fibrils of senile plaques. Acta Neuropathol (Berl) 1984;63:296-300.
-
(1984)
Acta Neuropathol
, vol.63
, pp. 296-300
-
-
Ishii, T.1
Haga, S.2
-
87
-
-
0026757992
-
Complement proteins and complement inhibitors in Alzheimer's disease
-
McGeer PL, McGeer EG. Complement proteins and complement inhibitors in Alzheimer's disease. Res Immunol 1992; 143:621-624.
-
(1992)
Res Immunol
, vol.143
, pp. 621-624
-
-
McGeer, P.L.1
McGeer, E.G.2
-
88
-
-
0026783495
-
Activated microglia and cerebral amyloid deposits in Alzheimer's disease
-
Rozenmuller JM, van der Valk P, Eikelenboom P. Activated microglia and cerebral amyloid deposits in Alzheimer's disease. Res Immunol 1992;143:646-649.
-
(1992)
Res Immunol
, vol.143
, pp. 646-649
-
-
Rozenmuller, J.M.1
Van Der Valk, P.2
Eikelenboom, P.3
-
89
-
-
0026470167
-
MHC class II-positive microglia in human brain: Association with Alzheimer's lesions
-
Perlmutter LS, Scott SA, Barron E, Chui HC. MHC class II-positive microglia in human brain: association with Alzheimer's lesions. J Neurosci Res 1992;33:549-558.
-
(1992)
J Neurosci Res
, vol.33
, pp. 549-558
-
-
Perlmutter, L.S.1
Scott, S.A.2
Barron, E.3
Chui, H.C.4
-
90
-
-
0029811901
-
Arthritis and antiinflammatory agents as possible protective factors for Alzheimer's disease: A review of 17 epidemiologic studies
-
McGeer PL, Schulzer M, McGeer EG. Arthritis and antiinflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies. Neurology 1996;47:425-432.
-
(1996)
Neurology
, vol.47
, pp. 425-432
-
-
McGeer, P.L.1
Schulzer, M.2
McGeer, E.G.3
-
92
-
-
0027268393
-
Clinical trial of indomethacin in Alzheimer's disease
-
Rogers J, Kirby LC, Hempelman SR, et al. Clinical trial of indomethacin in Alzheimer's disease. Neurology 1993;43: 1609-1611.
-
(1993)
Neurology
, vol.43
, pp. 1609-1611
-
-
Rogers, J.1
Kirby, L.C.2
Hempelman, S.R.3
-
93
-
-
0029817788
-
A pilot study of prednisone in Alzheimer's disease
-
Aisen PS, Marin D, Altsteil L, et al. A pilot study of prednisone in Alzheimer's disease. Dementia 1996;7:201-206.
-
(1996)
Dementia
, vol.7
, pp. 201-206
-
-
Aisen, P.S.1
Marin, D.2
Altsteil, L.3
-
94
-
-
0028044609
-
Towards a better aspirin
-
Vane J. Towards a better aspirin. Nature 1994;367:215-216.
-
(1994)
Nature
, vol.367
, pp. 215-216
-
-
Vane, J.1
-
95
-
-
0026735231
-
CDNa cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase
-
O'Banion MK, Winn VD, Young DA. CDNA cloning and functional activity of a glucocorticoid-regulated inflammatory cyclooxygenase, Proc Natl Acad Sci USA 1992;89:4888-4892.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 4888-4892
-
-
O'Banion, M.K.1
Winn, V.D.2
Young, D.A.3
-
96
-
-
0028846219
-
Induction by lipopolysaccaride of cyclooxygenase-2 mRNA in rat brain: Its possible role in the febrile response
-
Cao C, Matsumura K, Yamagata K, Watanabe Y. Induction by lipopolysaccaride of cyclooxygenase-2 mRNA in rat brain: its possible role in the febrile response. Brain Res 1995;697: 187-196.
-
(1995)
Brain Res
, vol.697
, pp. 187-196
-
-
Cao, C.1
Matsumura, K.2
Yamagata, K.3
Watanabe, Y.4
-
97
-
-
0030998896
-
The search for disease-modifying treatment for Alzheimer's disease
-
Aisen PS, Davis KL. The search for disease-modifying treatment for Alzheimer's disease. Neurology 1997;48(suppl 6): S35-41.
-
(1997)
Neurology
, vol.48
, Issue.6 SUPPL.
-
-
Aisen, P.S.1
Davis, K.L.2
-
98
-
-
0027450308
-
Inotropic glutamate receptor subtypes activate c-fos transcription by distinct calcium-requiring intracellular signaling pathways
-
Lerea LS, Macnamara JO. Inotropic glutamate receptor subtypes activate c-fos transcription by distinct calcium-requiring intracellular signaling pathways. Neuron 1993;10:31-41.
-
(1993)
Neuron
, vol.10
, pp. 31-41
-
-
Lerea, L.S.1
Macnamara, J.O.2
-
99
-
-
0027978247
-
New opportunities in AD research: Role of immunoinflammatory responses and glia
-
Frederickson RCA, Brunden KR. New opportunities in AD research: role of immunoinflammatory responses and glia. Alzheimers Dis Assoc Disord 1994;8:159-165.
-
(1994)
Alzheimers Dis Assoc Disord
, vol.8
, pp. 159-165
-
-
Frederickson, R.C.A.1
Brunden, K.R.2
-
100
-
-
0029087595
-
Predicting response to cholinergic inhibitors in Alzheimer's disease
-
Schneider LS, Farlow MR. Predicting response to cholinergic inhibitors in Alzheimer's disease. CNS Drugs 1995;4:114-124.
-
(1995)
CNS Drugs
, vol.4
, pp. 114-124
-
-
Schneider, L.S.1
Farlow, M.R.2
-
101
-
-
0344173381
-
A 25-week, double-blind, placebo-controlled, trial of eptastigmine in patients with diagnosis of probable Alzheimer's disease
-
Canal N, Imbimbo BP, Lucchelli PE, for the Eptastigmine Study Group. A 25-week, double-blind, placebo-controlled, trial of eptastigmine in patients with diagnosis of probable Alzheimer's disease. Eur J Neurol 1996;3(suppl 5):238.
-
(1996)
Eur J Neurol
, vol.3
, Issue.5 SUPPL.
, pp. 238
-
-
Canal, N.1
Imbimbo, B.P.2
Lucchelli, P.E.3
-
102
-
-
0345467146
-
The effects of tacrine in patients with mild versus moderate stage Alzheimer's disease
-
Farlow MR, Brashear A, Hui S, et al. The effects of tacrine in patients with mild versus moderate stage Alzheimer's disease. Neurobiol Aging 1994;15(suppl 4):331.
-
(1994)
Neurobiol Aging
, vol.15
, Issue.4 SUPPL.
, pp. 331
-
-
Farlow, M.R.1
Brashear, A.2
Hui, S.3
-
103
-
-
0005872618
-
Severity of Alzheimer's disease and response to cholinergic therapy
-
Schneider LS, Farlow MR. Severity of Alzheimer's disease and response to cholinergic therapy. Eur J Neurol 1996; 3(suppl 5):238.
-
(1996)
Eur J Neurol
, vol.3
, Issue.5 SUPPL.
, pp. 238
-
-
Schneider, L.S.1
Farlow, M.R.2
-
104
-
-
0028085285
-
Lewy bodies and response to tacrine in Alzheimer's disease
-
Levy R, Eagger S, Griffiths M, et al. Lewy bodies and response to tacrine in Alzheimer's disease [letter]. Lancet 1994;343:176.
-
(1994)
Lancet
, vol.343
, pp. 176
-
-
Levy, R.1
Eagger, S.2
Griffiths, M.3
-
106
-
-
0007691164
-
Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer's disease
-
Poirier J, Delisle M-C, Quirion R, et al. Apolipoprotein E4 allele as a predictor of cholinergic deficits and treatment outcome in Alzheimer's disease. Proc Natl Acad Sci USA 1995;92:12260-12264.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 12260-12264
-
-
Poirier, J.1
Delisle, M.-C.2
Quirion, R.3
-
107
-
-
0343207754
-
Apolipoprotein e genotype predicts response to tacrine in Alzheimer's disease
-
Farlow MR, Lahiri D, Hui S, Davignon J. Apolipoprotein E genotype predicts response to tacrine in Alzheimer's disease [abstract]. Neurology 1996;46(suppl 2):A217.
-
(1996)
Neurology
, vol.46
, Issue.2 SUPPL.
-
-
Farlow, M.R.1
Lahiri, D.2
Hui, S.3
Davignon, J.4
|