Involvement of IL-10 in induction of autoimmune hemolytic anemia in anti-erythrocyte Ig transgenic mice

International Immunology

Volumn 10, Issue 8, 1998, Pages 1039-1047

  Nisitani, Sazuku ^a,c   Sakiyama, Toshio ^b,c   Honjo, Tasuku ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Kagoshima City Hospital   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Autoimmunity; B lymphocytes; Cytokines; T lymphocytes; Transgenic knockout

Indexed keywords

ERYTHROCYTE ANTIBODY; INTERLEUKIN 10; INTERLEUKIN 5; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE HEMOLYTIC ANEMIA; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TRANSGENIC MOUSE;

ANEMIA, HEMOLYTIC, AUTOIMMUNE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD5; AUTOANTIBODIES; B-LYMPHOCYTES; CELL COUNT; CLONAL DELETION; DNA-BINDING PROTEINS; ERYTHROCYTES; FLOW CYTOMETRY; HEMATOCRIT; INTERLEUKIN-10; INTERLEUKIN-5; INTESTINAL MUCOSA; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PERITONEUM; T-LYMPHOCYTES; THYMUS GLAND;

EID: 0031879765     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/10.8.1039     Document Type: Article

References (48)

1. Solvason, N., Lehuen, A. and Kerney, J. F. 1991. An embryonic source of Ly1 but not conventional B cells. Int. Immunol. 3:543.
2. Godin, I. E., Garcia-Porrero, J. A., Coutinho, A., Dieterlen-Lievre, J. A. and Marcos, M. A. R. 1993. Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors. Nature 364:67.
3. Marcos, M. A. R., Huetz, F., Pereira, P., Andreu, J.L., Martinez-A., C. and Coutinho, A. 1989. Further evidence for coelomic-associated B lymphocytes. Eur. J Immunol. 19:2031.
4. Hayakawa, K., Hardy, R. R., Herzenberg, L. A. and Herzenberg. L. A. 1985. Progenitors for Ly-1 B cells are distinct from progenitors for other B cells. J. Exp. Med. 161:1554.
5. Hayakawa, K., Hardy, R. R. and Herzenberg, L. A. 1986. Peritoneal Ly-1 B cells, genetic control, autoantibody production, increased lambda light chain expression. Eur. J. Immunol. 16:450.
6. Khan, W. N., Alt, F. W., Gerstein, R. M., Malynn, B. A., Larsson, I., Rathbun, G., Davidson, L., Müller, S., Kantor, A. B., Herzenberg, L. A., Rosen, F. S. and Sidras, P. 1996. Defective B cell development and function in Btk-deficient mice. Immunity 3:283.
7. Kerner, J. D., Appleby, M. W., Mohr, R. N., Chien, S., Rawlings, D., Maliszewski, C. R., Witte, O. N and Permutter, R. M. 1996. Impaired expansion of mouse B cell progenitors lacking Btk. Immunity 3:301.
8. + B cells in viable motheaten and normal mice. Science 232:1423.
9. + B cells. J. Immunol. 144:4218.
10. Ishida, H., Hastings, R., Kearney, J. and Howard, M. 1992. Continuous anti-interleukin 10 antibody administration depletes mice of Ly-1 B cells but not conventional B cells. J. Exp. Med. 175:1213.
11. + (CD5) B cells that recognize phosphatidyl choline. Relationship to cells that secrete hemolytic antibody specific for autologous erythrocytes. J. Exp. Med. 168:687.
12. H gene family encodes anti-bromelinized mouse red blood cell autoantibodies. Eur. J. Immunol. 18:1521.
13. Pennell, C. A., Mercolino, T. J., Grdina, T. A., Arnold, L. W., Haughton, G. and Clarke, S. H. 1989. Biased immunoglobulin variable region gene expression by Ly-1 B cells due to clonal selection. Eur. J. Immunol. 19:1289.
14. Herzenberg, L. A., Stall, A. M., Lalor, P. A. Sidman, C., Moore, W. A., Parks, D. R. and Herzenberg, L. A. 1986. The LY-1 B lineage. Immunol. Rev. 93:81.
15. Kroese, F. G. M., Butcher, E. C., Stall, A. M., Lalor, P. A., Adams, S. and Herzenberg, L. A. 1989. Many of the IgA producing plasma cells in the murine gut are derived from self-replenishing precursors in the peritoneal cavity. Int. Immunol. 1:75.
16. + B cells upon transfer of peritoneal cells into allotype-congenic, newborn mice. Eur. J. Immunol. 17:521.
17. + and conventional B lymphocytes. Eur. J. Immunol. 19:1117.
18. Kroese, F. G. M., Ammerlaan, W. A. M. and Kantor, A. B. 1993. Evidence that intestinal IgA plasma cells in μ, κ transgenic mice are derived from B-1 (Ly-1 B) cells. Int. Immunol. 5:1317.
19. Pecquet, S. S., Ehrat, C. and Ernst, P. B. 1992. Enhancement of mucosal antibody responses to Salmonella typhimurium and the microbial hapten phosphorylcholine in mice with X-linked immunodeficiency by precursors from the peritoneal cavity. Infect. Immunol. 60:503.
20. Hayakawa, K., Hardy, R. R., Parks, D. R. and Herzenberg, L. A. 1983. The 'Ly-1 B' cell subpopulation in normal, immunodefective, and autoimmune mice. J. Exp. Med. 157:202.
21. + B cells. Science 236:81.
22. Plater-Zyberk, C., Maini, R. N., Lam, K., Kennedy, T. D. and Janossy, G. 1985. A rheumatoid arthritis B cell subset expresses a phenotype similar to that in chronic lymphocytic leukemia. Arthritis Rheum. 28:971.
23. Hayakawa, K., Hardy, R. R., Honda, M., Herzenberg, L. A., Steinberg, A. D. and Herzenberg, L. A. 1984. Ly-1 B cells: functionally distinct lymphocytes that secrete IgM autoantibodies. Proc. Natl Acad. Sci. USA 81:2494.
24. H11 family. J. Immunol. 142:3643.
25. + B-cell subset. Science 236:77.
26. Okamoto, M., Murakami, M., Shimizu, A., Ozaki, S., Tsubata, T., Kumagai, S. and Honjo, T. 1992. A transgenic model of autoimmune hemolytic anemia. J. Exp. Med. 175:71.
27. Murakami, M., Tsubata, T., Okamoto, M., Shimizu, A., Kumagai, S., Imura, H. and Honjo, T. 1992. Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice. Nature 357:77.
28. Murakami, M., Tsubata, T., Shinkura, R., Nisitani, S., Okamoto, M., Yoshioka, H., Usui, T., Miyawaki, S. and Honjo, T. 1994. Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse. J. Exp. Med. 180:111.
29. Murakami, M., Nakajima, K., Yamazaki, K., Muraguchi, T., Serikawa, T. and Honjo, T. 1997. Effect of breeding environments on generation and activation of autoreactive B-1 cells in anti-red blood cell autoantibody transgenic mice. J. Exp. Med. 185:791.
30. Nisitani, S., Tsubata, T., Murakami, M. and Honjo, T. 1995. Administration of interleukin-5 or -10 activates peritoneal B-1 cells and induces autoimmune hemolytic anemia in anti-erythrocyte autoantibody-transgenic mice. Eur. J. Immunol. 25:3047
31. Shinkai, Y., Rathbun, G., Lam, K.-P., Oltz, E. M., Stewart, V., Mendelsohn, M., Charron, J., Datta, M., Young, F., Stall, A. M. and Alt, F. W. 1992. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J recombination. Cell 68:855.
32. Ishida, Y., Nishi, M., Taguchi, O., Inaba, K., Hattori, M., Minato, N., Kawaichi, M. and Honjo, T. 1989. Expansion of natural killer cells but not T cells in human IL-2/IL-2 receptor (Tac) transgenic mice. J. Exp. Med. 170:1103.
33. Nisitani, S., Tsubata, T., Murakami, M and Honjo, T. 1993. The bcl-2 gene product inhibits clonal deletion of self-reactive B lymphocytes in the periphery but not in the bone marrow. J. Exp. Med. 178:1247.
34. + cells, but affect their long-term life span. Immunity 5:217.
35. Parry, S. L., Hasbold, J., Holman, M. and Klaus, G. G. 1994. Hypercross-linking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40. J. Immunol. 152:2821.
36. Nomura, T., Han, H., Howard, M. C., Yagita, H., Yakura, H., Honjo, T. and Tsubata, T. 1996. Antigen receptor-mediated B cell death is blocked by signaling via CD72 or treatment with dextran sulfate and is defective in autoimmunity-prone mice. Int. Immunol. 8:867.
37. + T cells provide B cell help. J. Exp. Med. 175:695.
38. Xu-Amano, J., Kiyono, H., Jackson, R. J., Staats, H. F., Fujihashi, K., Barrows, P. D., Elson, C. O., Pillai, S. and McGhee, J. R. 1993. Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues. J. Exp. Med. 178:1309.
39. 1 mice. J. Exp. Med. 179:305.
40. Fiorentino, D. F., Zlotnik, A., Mosmann, T. R., Howard, M. and O'Garra, A. 1991. IL-10 inhibits cytokines production by activated macrophages. J. Immunol. 147:3815.
41. Barsig, J., Küsters, S., Vogt, K., Volk, H.-D., Tiegs, G. and Wendel, A. 1995. Lipopolysaccharide-induced interleukin-10 in mice: role of endogenous tumor necrosis factor-α. Eur. J. Immunol. 25:2888.
42. Wanidworanun, C. and Strober, W. 1993. Predominant role of tumor necrosis factor-α in human monocyte IL-10 synthesis. J. Immunol. 151:6853.
43. Platzer, C., Meisei, C., Vogt, K., Platzer, M. and Volk, H.-D. 1995. Up-regulation of monocytic IL-10 by tumor necrosis factor-α and cAMP elevating drugs. Int. Immunol. 7:517.
44. O'Garra, A., Chang, R., Go, N., Hastings, R., Haughton, G. and Howard, M. 1992. Ly-1 B (B-1) cells are the main source of B cell-derived interleukin 10. Eur. J. Immunol. 22:711.
45. Rousset, F., Garcia, E., Defrance, T., Péronne, C., Vezzio, N., Hsu, D.-H., Kastelein, R., Moore, K. W. and Banchereau, J. 1992. Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. Proc. Natl Acad. Sci. USA 89:1890.
46. Fluckiger, A.-C., Garrone, P., Durand, I., Galizzi, J-P. and Banchereau, J. 1993. Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemia B lymphocytes. J. Exp. Med. 178:1473.
47. Wetzel, G. D. 1989. Interluekin 5 regulation of peritoneal Ly-1 B lymphocyte proliferation, differentiation and autoantibody secretion. Eur. J. Immunol. 19:1701.
48. Ozaki, S., Nagasawa, R., Sato, H. and Shirai, T. 1984. Hybridoma autoantibodies to erythrocytes from NZB mice and the induction of hemolytic anemia. Immunol. Lett. 8:115.