Toluene alters brainstem enkephalinergic system in rats

Industrial Health

Volumn 36, Issue 3, 1998, Pages 247-251

  Gandarias, J M D ^a   Echevarria, E ^a   Serrano, R ^a   Silio, M ^a   Casis, L ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Enkephalin; Rat brain; Toluene

Indexed keywords

LEUCINE ENKEPHALIN; TOLUENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CONTROLLED STUDY; MALE; NEUROTOXICITY; NONHUMAN; OCCUPATIONAL EXPOSURE; RAT; RESPIRATION CONTROL; RESPIRATION DEPRESSION;

ANIMALIA;

EID: 0031879368     PISSN: 00198366     EISSN: None     Source Type: Journal    
DOI: 10.2486/indhealth.36.247     Document Type: Article

References (34)

1. Low LK, Meeks JR, McKerer CR (1988) Health effects of the alkylbenzenes. I. Toluene. Toxicol Ind Health 4 (1), 49-75.
2. Streicher HZ, Gabow PA, Moss AM, Kono D, Kaeny WD (1981) Syndromes of toluene sniffing in adults. Ann Int Med 94, 758-62.
3. Devathasan G, Low D, Teoh PC, Wan SH, Wong PK (1984) Complications of Chronic glue (toluene) abuse in adolescents. Aust N Z J Med 14 (1), 39-43.
4. Donald JM, Hooper J, Hopenhayn-Rich L (1991) Reproductive and developmental toxicity of toluene: a review. Environ Health Perspect 94, 237-44.
5. Tan WP, Seow E (1997) Case reports on acute toluene poisoning during parquet flooring. Ann Acad Med Singapore 26(1), 138-40.
6. Bakinson MA, Jones RD (1985) Gassings due to methylene chloride, xylene, toluene and styrene reported to Her Majesty's Factory Inspectorate 1961-80. Brit J Ind Med 42 (3), 184-90.
7. Baelum J, Andersen IB, Lundqvist GR, Molhave L, Pedersen OF, Vaeth M, Wyon DP (1985) Response of solvent-exposed printers and unexposed controls to six-hour toluene exposure. Scand J Work Environ Health 11 (4), 271-80.
8. Glaser J, Dessauer M, Proksch E (1985) Akute Polyneuropathie durch Inhalation von Losemittelgemischen in handelsublichen Lackentfernern und Verdunnern. Dtsch Med Wochenschr 110 (36), 1374-7.
9. Welch L, Kirshner H, Heath A, Gilliland R, Broyles S (1991) Chronic neuropsychological and neurological impairment following acute exposure to a solvent mixture of toluene and methyl ethyl ketone (MEK). J Toxicol Clin Toxicol 29 (4), 435-45.
10. Flanagan RJ, Ruprah M, Meredith TJ, Ramsey JD (1990) An introduction to the clinical toxicology of volatile substances. Drug Saf 5 (5), 359-83.
11. Gospe SMJr, Calaban MJ (1988) Central nervous system distribution of inhaled toluene. Fund Appl Toxicol 11, 540-5.
12. Bradley PB, Lucy AP (1983) Cholinoceptive properties of respiratory neurons in the rat medulla. Neuropharmacology 22, 853-8.
13. Blanchi AL, Denavit-Saubié M, Champagnat J (1995) Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters. Physiol Rev 75(1), 1-45.
14. Denavit-Saubié M, Champagnat J, Ziegelgänsberger W (1978) Effects of opiates and methionone-enkephalin on pontine and bulbar respiratory neurones of the cat. Brain Res 155, 55-67.
15. Rondouin G, Boudinot E; Champagnat J, Denavit-Saubié M (1981) Effects of sulfonated leu-enkephalin applied iontophoretically to cat respiratory neurones. Neuropharmacology 20, 963-7.
16. Kuznetsov VI, Godukhin OV (1985) Mechanism of methionine-enkephalin modulation of glutamatergic transmission in the rat striatum. Neurosci Lett 57, 143-6.
17. Howard BR, Tabatabai M (1975) Localization of the medullary respiratory neurons in rats by microelectrode recording. J Appl Physiol 39, 812-7.
18. Honma T (1983) Changes in acetylcholine metabolism in rat brain after a short-term exposure to toluene and n-hexane. Toxicol Lett 16, 17-22.
19. Fuxe K, Andersson K, Nilsen OG, Toftgard R, Eneroth P, Gustafsson JA (1982) Toluene and telencephalic dopamine: selective reduction of amine turnover in discrete dopamine nerve terminal systems of the anterior caudate nucleus by low concentrations of toluene. Toxicol Lett 112, 115-23.
20. Fuxe K, Martire M, Von Euler G, Agnati LF, Hansson T, Andersson J, Gustafsson A, Harfstrand A (1987) Effects of subacute treatment with toluene on cerebrocortical alpha and beta adrenergic receptors in the rat. Evidence for an increased number and a reduced affinity of beta adrenergic receptors. Acta Physiol Scand 130, 307-11.
21. Honma T, Sudo A, Miyagawa M, Sato H, Hasegawa H (1983) Significant changes in the amount of neurotransmitter and related substances in rat brain induced by subacute exposure to low levels of toluene and xylene. Ind Health 21, 143-51.
22. Gros C, Giros B, Schwartz JC (1985) Identification of aminopeptidase M as an enkephalin-inactivating enzyme in rat cerebral membranes. Biochemistry 24, 2179-85.
23. Johnson GD, Hersch LB (1990) Studies on the subsite specifity of the rat brain puromycin-sensitive aminopeptidase. Arch Biochem Biophys 276, 305-9.
24. Gandarias JMde, Echevarría E, Irazusta J, Casis E, Casis L (1993) Lys- and Leu-aminopeptidase activity after acute toluene exposure in the rat brain. Toxicol Ind Health 9 (3), 1-7.
25. Gandarias JMde, Echevarría E, Serrano R, Irazusta J, Casis L (1994) Effect of subacute toluene administration on the enkephalinergic neuromodulatory system in rats and protective action of ganglioside treatments. Toxicol Ind Health 10 (3), 155-61.
26. Pappolla M, Penton R, Weiss HS, Miller CHJr, Sahenk Z, Autilio-Gambetti L, Gambetti P (1987) Carbon disulfide axonopathy. Another experimental model characterized by acceleration of neurofilament transport and distinct changes of axonal size. Brain Res 424, 272-80.
27. Björklund A, Hökfelt T (1985) Handbook of chemical neuroanatomy. Volume 2. GABA and neuropeptides in the central nervous system. Amsterdam: Elsevier Science Publishers.
28. Huang J, Asaeda N, Takeuchi Y, Shibata E, Hisanaga N, Ono Y, Kato K (1992) Dose dependent effects of chronic exposure to toluene on neuronal and glial cell marker proteins in the central nervous system of rats. Brit J Ind Med 49, 282-6.
29. Von Euler G, Fuxe K, Hansson T, Gustafsson JA (1989) Effects of toluene treatment in vivo and in vitro on the binding characteristics of 3H-Neurotensin in rat striatal membranes. Toxicology 49, 149-54.
30. Von Euler G, Fuxe K, Hansson T, Benfenati F, Agnati LF, Gustafsson JA (1987) Effects of subacute toluene exposure on protein phosphorylation levels in rat frontoparietal and striatal membranes. Acta Physiol Scand 131, 113-8.
31. Grunstein MM, Grunstein JS (1982) Maturational effect of enkephalin on respiratory control in newborn rabbits. J Appl Physiol 53, 1063-70.
32. Pasternal GW, Zhong-Zhang A, Tecott L (1980) Developmental differences between high and low affinity opiate binding studies: their relationship to analgesia and respiratory depression. Life Sci 27, 1185-90.
33. Santiago TV, Teodoro V, Edelman NH (1985) Opioids and breathing. J Appl Physiol 59, 1675-85.
34. 2-met-enkephalinamide, and met-enkephalin injected into the lateral ventricule and the pontomedullary subarachnoid space. Brain Res 199, 197-206.