Co-culture of synovial fibroblasts and differentiated U937 cells is sufficient for high interleukin-6 but not interleukin-1β or tumour necrosis factor-α release

British Journal of Rheumatology

Volumn 37, Issue 2, 1998, Pages 148-156

  Chen, V ^a   Croft, D ^a   Purkis, P ^b   Kramer, I M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ROYAL LONDON HOSPITAL   (United Kingdom)

Author keywords

Co culture; Cytokines; Fibroblast like synoviocyte; Interleukin 6; U937

Indexed keywords

CD11B ANTIGEN; CD14 ANTIGEN; COLLAGENASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; PHORBOL ESTER; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CELL INFILTRATION; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; INFLAMMATION; MONOCYTE; PRIORITY JOURNAL; SYNOVIAL FLUID; SYNOVIOCYTE; SYNOVIUM;

ANTIGENS, DIFFERENTIATION; ARTHRITIS, RHEUMATOID; CELL COUNT; CELL DIFFERENTIATION; COCULTURE TECHNIQUES; DNA PRIMERS; FIBROBLASTS; FLOW CYTOMETRY; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; MONOCYTES; RNA, MESSENGER; SKIN; SYNOVIAL FLUID; SYNOVIAL MEMBRANE; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031878898     PISSN: 02637103     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Feldmann M, Brennan FM, Chantry D, Haworth C, Turner M, Abney E et al. Cytokine production in the rheumatoid joint: implications for treatment. Ann Rheum Dis 1990;49:480-6.
2. Arend WP, Dayer JM. Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis Rheum 1990;33:305-15.
3. Arend WP, Dayer JM. Inhibition of the production and effects of interleukin-1 and tumour necrosis factor α in rheumatoid arthritis. Arthritis Rheum 1995;38:151-60.
4. Schnyder J, Payne T, Dinarello CA. Human monocyte or recombinant interleukin 1's are specific for the secretion of metalloproteinase from chondrocytes. J Immunol 1987;138:496-503.
5. Shinmei M, Masuad K, Kikuchi T, Shimomura Y. Interleukin 1, tumour necrosis factor, and interleukin 6 as mediators of cartilage destruction. Semin Arthritis Rheum 1989;18(suppl. 1):27-32.
6. MacNaul KL, Chartrain N, Lark M, Tocci J, Hutchinson NI. Discoordinate expression of stromelysin, collagenase and tissue inhibitor of metalloproteinases-1 in rheumatoid human synovial fibroblasts. J Biol Chem 1990; 265:17238-45.
7. Unemori EN, Hibbs MS, Amento EP. Constitutive expression of a 92-kDa gelatinase (Type V collagenase) by rheumatoid synovial fibroblasts and its induction in normal human fibroblasts by inflammatory cytokines. J Clin Invest 1991;88:1656-62.
8. Saklatvala J. Tumour necrosis factor α stimulates resorption and inhibits synthesis of proteoglycan in cartilage. Nature 1986;322:547-9.
9. Nietfeld JJ, Wilbrink B, Helle M, van Roy JL, den Otter W, Swaak AJ et al. Interleukin-1 induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human articular cartilage. Arthritis Rheum 1990;33:1695-701.
10. Burdin N, Van Kooten C, Galibert L, Abrams JS, Wij denes J, Banchereau J et al. Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes. J Immunol 1995;154:2533-44.
11. Brown PB, Nardella FA, Mannik M. Human complement activation by self-association IgG rheumatoid factors. Arthritis Rheum 1982;25:1101-7.
12. Guerne PA, Zuraw BL, Vaughan JH, Carson DA, Lotz M. Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis. J Clin Invest 1989;83:585-92.
13. Rosenbaum JT, Cugnini R, Tara DC, Hefeneider S, Ansel JC. Production and modulation of IL-6 synthesis by synoviocytes derived from patients with arthritic disease. Ann Rheum Dis 1992;51:198-202.
14. Zvaifler NJ, Boyle D, Firestein GS. Early synovitis -synoviocytes and mononuclear cells. Semin Arthritis Rheum 1994;23:11-6.
15. Zvaifler NJ. Macrophages and the synovial lining. Scand J Rheumatol 1995;24:67-75.
16. Burmester GR, Dimitriu-Bona A, Waters SJ, Winchester RJ. Identification of three major synovial lining cell populations by monoclonal antibodies directed to Ia antigens and antigens associated with monocytes/macro-phages and fibroblasts. Scand J Immunol 1983;17:69-82.
17. Hogg N, Palmer PG, Revell PA. Mononuclear phagocytes of normal and rheumatoid synovial membrane identified by monoclonal antibodies. Immunology 1985;56:673-81.
18. Wilkinson LS, Edwards JCW, Poston RN, Haskard DO. Expression of vascular cell adhesion molecule-1 in normal and inflamed synovium. Lab Invest 1993;68:82-8.
19. Sundstrom C, Nilsson K. Establishment and characterization of a human histiocytic lymphoma cell line (U937). Int J Cancer 1976;17:565-72.
20. Harris P, Ralph P. Human leukemic models of myelomonocytic development: a review of the HL-60 and U937 cell lines. J Leukocyte Biol 1985;37:407-22.
21. Taimi M, Defacque H, Commes T, Favero J, Caron E, Marti J et al. Effect of retinoic acid and vitamin D on the expression of IL-1β, TNF-α and IL-6 in the human monocytic cell line U937. Immunology 1993;79:229-35.
22. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Anal Biochem 1987;162:156-9.
23. Navarro S, Debili N, Bernaudin JF, Vainchenker W, Doly J. Regulation of the expression of IL-6 in human monocytes. J Immunol 1989;142:4339-45.
24. Chomarat P, Rissoan MC, Pin JJ, Banchereau J, Miossec P. Contribution of IL-1, CD14, and CD13 in the increased IL-6 production induced by in vitro monocyte-synoviocyte interactions. J Immunol 1995; 155:3645-52.