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Volumn 26, Issue 3, 1998, Pages 107-119

Treatment of chronic stable angina with carvedilol: A multiple-action neurohormonal antagonist. A review of controlled clinical trials

Author keywords

Alpha blockade; Beta blockade; Carvedilol; Chronic stable angina pectoris; Multiple action neurohormonal antagonist

Indexed keywords

ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CARVEDILOL; CATECHOLAMINE; DOXAZOSIN; ISOSORBIDE DINITRATE; NEUROHORMONE; NIFEDIPINE; NITRATE; OXYGEN RADICAL; PROPRANOLOL; SCAVENGER; VERAPAMIL;

EID: 0031878751     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/030006059802600301     Document Type: Review
Times cited : (3)

References (50)
  • 1
    • 84965298874 scopus 로고
    • Epidemiology of Ischaemic Heart Disease
    • (Weatherall DJ, Ledingham JGG, Worell DA, eds) Oxford: Oxford University Press
    • Mann JI, Marmot MG: Epidemiology of Ischaemic Heart Disease. In: Oxford Textbook of Medicine, 2nd Edn (Weatherall DJ, Ledingham JGG, Worell DA, eds) Oxford: Oxford University Press, 1986; pp13.143-13.154.
    • (1986) Oxford Textbook of Medicine, 2nd Edn
    • Mann, J.I.1    Marmot, M.G.2
  • 3
    • 3543119041 scopus 로고
    • Angina pectoris. Definition and description
    • Julian DG, ed. New York: Churchill Livingstone
    • Matthews MB, Julian DE: Angina pectoris. Definition and description. In: Angina Pectoris, 2nd Edn (Julian DG, ed). New York: Churchill Livingstone, 1985; p2.
    • (1985) Angina Pectoris, 2nd Edn , pp. 2
    • Matthews, M.B.1    Julian, D.E.2
  • 4
    • 0023879355 scopus 로고
    • Echocardiographically detected left ventricular hypertrophy: Prevalence and risk factors. The Framingham Heart Study
    • Levy D, Anderson KM, Savage DD, et al: Echocardiographically detected left ventricular hypertrophy: prevalence and risk factors. The Framingham Heart Study. Ann Intern Med 1988; 108: 7-13.
    • (1988) Ann Intern Med , vol.108 , pp. 7-13
    • Levy, D.1    Anderson, K.M.2    Savage, D.D.3
  • 5
    • 0022400244 scopus 로고
    • Pharmacology of the nitrates in angina pectoris
    • Frishman WH: Pharmacology of the nitrates in angina pectoris. Am J Cardiol 1985; 56: 81-131.
    • (1985) Am J Cardiol , vol.56 , pp. 81-131
    • Frishman, W.H.1
  • 6
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF, Zawadski JV: The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980; 288: 373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadski, J.V.2
  • 7
    • 0023198721 scopus 로고
    • Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
    • Palmer RMJ, Ferrige AG, Moncada S: Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 1987; 327: 524-526.
    • (1987) Nature , vol.327 , pp. 524-526
    • Palmer, R.M.J.1    Ferrige, A.G.2    Moncada, S.3
  • 8
    • 0028365339 scopus 로고
    • Phenomenon of nitrate tolerance
    • Mangione NJ, Glasser SP: Phenomenon of nitrate tolerance. Am Heart J 1994; 128: 137-146.
    • (1994) Am Heart J , vol.128 , pp. 137-146
    • Mangione, N.J.1    Glasser, S.P.2
  • 9
    • 0028899858 scopus 로고
    • The role of nitrates in coronary heart disease
    • Abrams J. The role of nitrates in coronary heart disease. Arch Intern Med 1995; 155: 357-364.
    • (1995) Arch Intern Med , vol.155 , pp. 357-364
    • Abrams, J.1
  • 10
    • 0023611484 scopus 로고
    • Calcium channel antagonists, Part 1: Fundamental properties: mechanisms, classification, sites of action
    • Opie LH: Calcium channel antagonists, Part 1: Fundamental properties: mechanisms, classification, sites of action. Cardiovasc Drugs Ther 1987; 1: 411-430.
    • (1987) Cardiovasc Drugs Ther , vol.1 , pp. 411-430
    • Opie, L.H.1
  • 11
    • 0002199391 scopus 로고    scopus 로고
    • Drugs used for the treatment of myocardial ischaemia
    • (Hardman JG, Gilman AG, Limbird LE, eds). New York: McGraw-Hill
    • Robertson RM, Robertson D: Drugs used for the treatment of myocardial ischaemia. In: The Pharmacological Basis of Therapeutics, 9th Edn (Hardman JG, Gilman AG, Limbird LE, eds). New York: McGraw-Hill, 1996; pp759-779.
    • (1996) The Pharmacological Basis of Therapeutics, 9th Edn , pp. 759-779
    • Robertson, R.M.1    Robertson, D.2
  • 12
    • 0020673669 scopus 로고
    • Recent advanes in knowledge about beta-adrenergic receptors: Application to clinical cardiology
    • Watanabe AM: Recent advanes in knowledge about beta-adrenergic receptors: application to clinical cardiology. J Am Coll Cardiol 1993; 1: 82-89.
    • (1993) J Am Coll Cardiol , vol.1 , pp. 82-89
    • Watanabe, A.M.1
  • 13
    • 0016380525 scopus 로고
    • Beta-adrenergic receptor blocking agents in angina pectoris
    • Prichard BNC: Beta-adrenergic receptor blocking agents in angina pectoris. Drugs 1974; 7: 55-84
    • (1974) Drugs , vol.7 , pp. 55-84
    • Prichard, B.N.C.1
  • 14
    • 0021036873 scopus 로고
    • Basics for cardiovascular therapy with beta-blocking agents
    • Opie LH: Basics for cardiovascular therapy with beta-blocking agents. Am J Cardiol 1983; 52: 2D-9D.
    • (1983) Am J Cardiol , vol.52
    • Opie, L.H.1
  • 15
    • 0021229979 scopus 로고
    • Effect of propranolol on myocardial infarct size in a randomised blinded multicenter trial
    • Roberts R, Croft C, Gold HK, et al: Effect of propranolol on myocardial infarct size in a randomised blinded multicenter trial. New Engl J Med 1984; 311: 218-250.
    • (1984) New Engl J Med , vol.311 , pp. 218-250
    • Roberts, R.1    Croft, C.2    Gold, H.K.3
  • 16
    • 0022350075 scopus 로고
    • Six-year follow-up of the Norwegian Multicenter Study on Timolol after Acute Myocardial Infarction
    • Pedersen TR and the Norwegian Multicenter Study on Timolol after Acute Myocardial Infarction: Six-year follow-up of the Norwegian Multicenter Study on Timolol after Acute Myocardial Infarction. New Engl J Med 1985; 313: 1055-1056.
    • (1985) New Engl J Med , vol.313 , pp. 1055-1056
    • Pedersen, T.R.1
  • 17
    • 0019520254 scopus 로고
    • Effect on mortality of metoprolol after acute myocardial infarction
    • Hjalmarson A, Herlitz J, Malek I, et al: Effect on mortality of metoprolol after acute myocardial infarction. Lancet 1981; 2: 823-827.
    • (1981) Lancet , vol.2 , pp. 823-827
    • Hjalmarson, A.1    Herlitz, J.2    Malek, I.3
  • 18
    • 0021909115 scopus 로고
    • Beta blockade during and after myocardial infarction: An overview of the randomised trials
    • Yusuf S, Peto R, Lewis J, et al: Beta blockade during and after myocardial infarction: an overview of the randomised trials. Prog Cardiovasc Dis 1985; 27: 335-371.
    • (1985) Prog Cardiovasc Dis , vol.27 , pp. 335-371
    • Yusuf, S.1    Peto, R.2    Lewis, J.3
  • 19
    • 0025942936 scopus 로고
    • Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension)
    • Dahlöf B, Lindholm LH, Hansson L, et al: Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension). Lancet 1991; 338: 1281-1285.
    • (1991) Lancet , vol.338 , pp. 1281-1285
    • Dahlöf, B.1    Lindholm, L.H.2    Hansson, L.3
  • 20
    • 0000217817 scopus 로고    scopus 로고
    • Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists
    • (Hardman JG, Gilman AG, Limbird LE, eds). New York: McGraw-Hill
    • Hoffman BB, Lefkowitz RJ: Catecholamines, sympathomimetic drugs, and adrenergic receptor antagonists. In: The Pharmacological Basis of Therapeutics, 9th Edn (Hardman JG, Gilman AG, Limbird LE, eds). New York: McGraw-Hill, 1996; pp199-248.
    • (1996) The Pharmacological Basis of Therapeutics, 9th Edn , pp. 199-248
    • Hoffman, B.B.1    Lefkowitz, R.J.2
  • 21
    • 0023035701 scopus 로고
    • Antianginal efficacy of carvedilol, a beta-blocking drug with vasodilating activity
    • Rodrigues EA, Lahiri A, Hughes LO, et al: Antianginal efficacy of carvedilol, a beta-blocking drug with vasodilating activity. Am J Cardiol 1986; 58: 916-921.
    • (1986) Am J Cardiol , vol.58 , pp. 916-921
    • Rodrigues, E.A.1    Lahiri, A.2    Hughes, L.O.3
  • 22
    • 0024437823 scopus 로고
    • Effects of carvedilol in patients with left ventricular function due to ischaemic heart disease
    • Lahiri A, Rodrigues EA, DasGupta P, et al: Effects of carvedilol in patients with left ventricular function due to ischaemic heart disease. Zeitschr Kardiol 1989; 78(Suppl): 21-27.
    • (1989) Zeitschr Kardiol , vol.78 , Issue.SUPPL. , pp. 21-27
    • Lahiri, A.1    Rodrigues, E.A.2    DasGupta, P.3
  • 23
    • 0023180344 scopus 로고
    • Effects of a new vasodilating beta-blocking drug, carvedilol, on left ventricular function in stable angina pectoris
    • Lahiri A, Rodrigues EA, Al-Khawaja I, Raftery EB: Effects of a new vasodilating beta-blocking drug, carvedilol, on left ventricular function in stable angina pectoris. Am J Cardiol 1987; 59: 769-774.
    • (1987) Am J Cardiol , vol.59 , pp. 769-774
    • Lahiri, A.1    Rodrigues, E.A.2    Al-Khawaja, I.3    Raftery, E.B.4
  • 24
    • 0024146851 scopus 로고
    • Effects of carvedilol on left ventricular function in essential hypertension and ischaemic heart disease
    • Lahiri A, Rodrigues EA, Heber ME, et al: Effects of carvedilol on left ventricular function in essential hypertension and ischaemic heart disease. Drugs 1988; 36(Suppl 6): 141-143.
    • (1988) Drugs , vol.36 , Issue.6 SUPPL. , pp. 141-143
    • Lahiri, A.1    Rodrigues, E.A.2    Heber, M.E.3
  • 25
    • 0027167633 scopus 로고
    • Plasma norepinephrine, plasma renin activity and congestive heart failure. Relations to survival and the effects of therapy in V-HeFT II follow-up
    • Francis GS, Cohn JN, Johnson G, et al: Plasma norepinephrine, plasma renin activity and congestive heart failure. Relations to survival and the effects of therapy in V-HeFT II follow-up. Circulation 1993; 83(Suppl VI): VI40-VI48.
    • (1993) Circulation , vol.83 , Issue.6 SUPPL.
    • Francis, G.S.1    Cohn, J.N.2    Johnson, G.3
  • 26
    • 0030835669 scopus 로고    scopus 로고
    • Beneficial effects of intravenous and oral carvedilol treatment in acute myocardial infarction. A placebo-controlled randomized trial
    • Basu S, Senior R, Raval U, et al: Beneficial effects of intravenous and oral carvedilol treatment in acute myocardial infarction. A placebo-controlled randomized trial. Circulation 1997; 96: 183-191.
    • (1997) Circulation , vol.96 , pp. 183-191
    • Basu, S.1    Senior, R.2    Raval, U.3
  • 28
    • 0029998396 scopus 로고    scopus 로고
    • Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: The carvedilol-metoprol study
    • Jacob S, Rett K, Wickmayr M, et al: Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: the carvedilol-metoprol study. J Hypertens 1996; 14: 489-494.
    • (1996) J Hypertens , vol.14 , pp. 489-494
    • Jacob, S.1    Rett, K.2    Wickmayr, M.3
  • 29
    • 0028557459 scopus 로고
    • Adrenoreceptors, endothelial function, and lipid profile: Effects of atenolol, doxazosin, and carvedilol
    • González Maqueda I: Adrenoreceptors, endothelial function, and lipid profile: effects of atenolol, doxazosin, and carvedilol. Coron Artery Dis 1994; 5: 909-918.
    • (1994) Coron Artery Dis , vol.5 , pp. 909-918
    • González Maqueda, I.1
  • 30
    • 0027255323 scopus 로고
    • A double-blind comparison of the effects of carvedilol and captopril on serum lipid concentrations in patients with mild to moderate essential hypertension and dyslipidaemia
    • Hauf-Zachariou U, Widmann L, Zülsdorf B, et al: A double-blind comparison of the effects of carvedilol and captopril on serum lipid concentrations in patients with mild to moderate essential hypertension and dyslipidaemia. Eur J Clin Pharmacol 1993; 45: 95-100.
    • (1993) Eur J Clin Pharmacol , vol.45 , pp. 95-100
    • Hauf-Zachariou, U.1    Widmann, L.2    Zülsdorf, B.3
  • 31
    • 0023609542 scopus 로고
    • Acute hemodynamic effects of the vasodilating and β-blocking agent carvedilol in comparison to propranolol
    • Wendt T, van der Does R, Schräder R, et al: Acute hemodynamic effects of the vasodilating and β-blocking agent carvedilol in comparison to propranolol. J Cardiovasc Pharmacol 1987; 10(Suppl 11): 147-150.
    • (1987) J Cardiovasc Pharmacol , vol.10 , Issue.11 SUPPL. , pp. 147-150
    • Wendt, T.1    Van Der Does, R.2    Schräder, R.3
  • 32
    • 0027529916 scopus 로고
    • Carvedilol inhibits vascular smooth muscle cell proliferation
    • Sung C-P, Arleth AJ, Ohlstein EH: Carvedilol inhibits vascular smooth muscle cell proliferation. J Cardiovasc Pharmacol 1993; 21: 221-227.
    • (1993) J Cardiovasc Pharmacol , vol.21 , pp. 221-227
    • Sung, C.-P.1    Arleth, A.J.2    Ohlstein, E.H.3
  • 33
    • 0002881583 scopus 로고
    • Carvedilol, a new vasodilator and beta-adrenoreceptor antagonist, inhibits oxygen-radical-mediated lipid peroxidation in swine ventricular membranes
    • Yue T-L, Liu T, Feverstein G: Carvedilol, a new vasodilator and beta-adrenoreceptor antagonist, inhibits oxygen-radical-mediated lipid peroxidation in swine ventricular membranes. Pharmacol Commun 1992; 1: 27-35.
    • (1992) Pharmacol Commun , vol.1 , pp. 27-35
    • Yue, T.-L.1    Liu, T.2    Feverstein, G.3
  • 34
    • 0025309602 scopus 로고
    • Free radicals and other involvement during long-term myocardial ischaemia and reperfusion
    • Downey JM: Free radicals and other involvement during long-term myocardial ischaemia and reperfusion. Ann Rev Physiol 1990; 52: 487-504.
    • (1990) Ann Rev Physiol , vol.52 , pp. 487-504
    • Downey, J.M.1
  • 35
    • 0026779879 scopus 로고
    • Carvedilol, a new vasodilator and beta-adrenoreceptor antagonist, is an anti-oxidant and free radical scavenger
    • Yue T-L, Cheng H-Y, Lysko PG, et al: Carvedilol, a new vasodilator and beta-adrenoreceptor antagonist, is an anti-oxidant and free radical scavenger. J Pharmacol Exp Ther 1992; 263: 92-98.
    • (1992) J Pharmacol Exp Ther , vol.263 , pp. 92-98
    • Yue, T.-L.1    Cheng, H.-Y.2    Lysko, P.G.3
  • 36
    • 0029960787 scopus 로고    scopus 로고
    • Protective effects of carvedilol, a vasodilating β-adrenoceptor blocker, against in vivo low density lipoprotein oxidation in essential hypertension
    • Maggi E, Marchesi E, Covini D, et al: Protective effects of carvedilol, a vasodilating β-adrenoceptor blocker, against in vivo low density lipoprotein oxidation in essential hypertension. J Cardiovasc Pharmacol 1996; 27: 532-538.
    • (1996) J Cardiovasc Pharmacol , vol.27 , pp. 532-538
    • Maggi, E.1    Marchesi, E.2    Covini, D.3
  • 37
    • 0025719978 scopus 로고
    • Comparison of the effects of carvedilol, propranolol and verapamil on in vitro platelet function in healthy volunteers
    • Gasser JA, Betterridge DJ: Comparison of the effects of carvedilol, propranolol and verapamil on in vitro platelet function in healthy volunteers. J Cardiovasc Pharmacol 1991; 18(Suppl 4): 29-34.
    • (1991) J Cardiovasc Pharmacol , vol.18 , Issue.4 SUPPL. , pp. 29-34
    • Gasser, J.A.1    Betterridge, D.J.2
  • 38
    • 0021892838 scopus 로고
    • Efficacy of carvedilol (BM14,190), a new beta-blocking drug with vasodilating properties, in exercise-induced ischemia
    • Kaski JC, Rodriguez-Plaza L, Brown J, Maseri A: Efficacy of carvedilol (BM14,190), a new beta-blocking drug with vasodilating properties, in exercise-induced ischemia. Am J Cardiol 1985; 56: 35-40.
    • (1985) Am J Cardiol , vol.56 , pp. 35-40
    • Kaski, J.C.1    Rodriguez-Plaza, L.2    Brown, J.3    Maseri, A.4
  • 39
    • 0026582544 scopus 로고
    • Long-term efficacy and safety of carvedilol, a new β-blocking agent with vasodilating properties, in patients with chronic ischaemic heart disease
    • DasGupta P, Jain D, Lahiri A, Raftery EB: Long-term efficacy and safety of carvedilol, a new β-blocking agent with vasodilating properties, in patients with chronic ischaemic heart disease. Drug Invest 1992; 4: 263-272.
    • (1992) Drug Invest , vol.4 , pp. 263-272
    • DasGupta, P.1    Jain, D.2    Lahiri, A.3    Raftery, E.B.4
  • 40
    • 0023611757 scopus 로고
    • Anti-anginal efficacy of carvedilol, a new β-blocker with vasodilating action
    • Jamal SM, Freedman SB, Thomson A, et al: Anti-anginal efficacy of carvedilol, a new β-blocker with vasodilating action. J Cardiovasc Pharmacol 1987; 10(Suppl): 141-146.
    • (1987) J Cardiovasc Pharmacol , vol.10 , Issue.SUPPL. , pp. 141-146
    • Jamal, S.M.1    Freedman, S.B.2    Thomson, A.3
  • 41
    • 0025173108 scopus 로고
    • Evaluation of a new vasodilating β-blocking agent, carvedilol, in exertional angina using Holter monitoring
    • Kishida H, Saito T, Fukuma N, et al: Evaluation of a new vasodilating β-blocking agent, carvedilol, in exertional angina using Holter monitoring. Jpn Heart J 1990; 31: 449-460.
    • (1990) Jpn Heart J , vol.31 , pp. 449-460
    • Kishida, H.1    Saito, T.2    Fukuma, N.3
  • 42
    • 26844434820 scopus 로고
    • Effects of combined beta-blockage and calcium antagonists on myocardial ischaemia and ventricular function in stable angina
    • Rodrigues EA, Hains ABD, Lahiri A, et al: Effects of combined beta-blockage and calcium antagonists on myocardial ischaemia and ventricular function in stable angina. Clin Sci 1988; 75: 4P.
    • (1988) Clin Sci , vol.75
    • Rodrigues, E.A.1    Hains, A.B.D.2    Lahiri, A.3
  • 43
    • 0023922883 scopus 로고
    • Comparison of bevantalol and atenolol in chronic stable angina
    • Rodrigues EA, Lawrence JD, Dasgupta P, et al: Comparison of bevantalol and atenolol in chronic stable angina. Am J Cardiol 1988; 61: 1204-1209.
    • (1988) Am J Cardiol , vol.61 , pp. 1204-1209
    • Rodrigues, E.A.1    Lawrence, J.D.2    Dasgupta, P.3
  • 45
    • 0031010353 scopus 로고    scopus 로고
    • Carvedilol versus verapamil in chronic stable angina: A multicentre trial
    • Hauf-Zachariou U, Blackwood RA, Gunawardena KA, et al: Carvedilol versus verapamil in chronic stable angina: a multicentre trial. Eur J Clin Pharmacol 1997; 52: 95-100.
    • (1997) Eur J Clin Pharmacol , vol.52 , pp. 95-100
    • Hauf-Zachariou, U.1    Blackwood, R.A.2    Gunawardena, K.A.3
  • 46
    • 0026019668 scopus 로고
    • Treatment of chronic stable angina with carvedilol in comparison with nifedipine s.r
    • van der Does R, Eberhardt R, Derr I, et al: Treatment of chronic stable angina with carvedilol in comparison with nifedipine s.r. Eur Heart J 1991; 12: 60-64.
    • (1991) Eur Heart J , vol.12 , pp. 60-64
    • Van Der Does, R.1    Eberhardt, R.2    Derr, I.3
  • 47
    • 0026653288 scopus 로고
    • Efficacy and safety of carvedilol in comparison with nifedipine sustained-release in chronic stable angina
    • van der Does R, Eberhardt R, Derr I, Ehmer B: Efficacy and safety of carvedilol in comparison with nifedipine sustained-release in chronic stable angina. J Cardiovasc Pharmacol 1992; 19(Suppl): 122-127.
    • (1992) J Cardiovasc Pharmacol , vol.19 , Issue.SUPPL. , pp. 122-127
    • Van Der Does, R.1    Eberhardt, R.2    Derr, I.3    Ehmer, B.4
  • 48
    • 0026751595 scopus 로고
    • A comparison of carvedilol with a combination of propranolol and isosorbide dinitrate in the chronic treatment of stable angina
    • Nahrendorf W, Rading A, Steinig G, et al: A comparison of carvedilol with a combination of propranolol and isosorbide dinitrate in the chronic treatment of stable angina. J Cardiovasc Pharmacol 1992; 19(Suppl 1): 114-116.
    • (1992) J Cardiovasc Pharmacol , vol.19 , Issue.1 SUPPL. , pp. 114-116
    • Nahrendorf, W.1    Rading, A.2    Steinig, G.3
  • 50
    • 0031468224 scopus 로고    scopus 로고
    • Carvedilol in comparison and in combination with isosorbide dinitrate sustained in patients with chronic stable effort-induced angina pectoris
    • Hauf-Zachariou U, Pfarr E, van der Does R: Carvedilol in comparison and in combination with isosorbide dinitrate sustained in patients with chronic stable effort-induced angina pectoris. Clin Drug Invest 1997; 14: 465-473.
    • (1997) Clin Drug Invest , vol.14 , pp. 465-473
    • Hauf-Zachariou, U.1    Pfarr, E.2    Van Der Does, R.3


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