Protein complex formation between Msx1 and Lhx2 homeoproteins is incompatible with DNA binding activity

Differentiation

Volumn 63, Issue 3, 1998, Pages 151-157

  Bendall, Andrew J ^a,b   Rincón Limas, Diego E ^c   Botas, Juan ^c   Abate Shen, Cory ^a,b  

^a RUTGERS UNIVERSITY   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN;

ARTICLE; CELL PROLIFERATION; COMPLEX FORMATION; EMBRYO; EMBRYO DEVELOPMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REPRESSOR GENE;

EID: 0031878584     PISSN: 03014681     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-0436.1998.6330151.x     Document Type: Article

References (37)

1. Agulnick AD, Taira M, Breen JJ, Tanaka T, Dawid IB, Westphal H (1996) Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins. Nature 384:270-272
2. Albrecht U, Eichele G, Helms JA, Lu H-C (1997) Visualization of gene expression patterns by in situ hybridization. In: Daston GP (ed) Molecular and Cellular Methods in Developmental Toxicology, CRC Press, Boca Raton, pp 23-48
3. Brown JM, Wedden SE, Millburn GH, Robson LG, Hill RE, Davidson DR, Tickle C (1993) Experimental analysis of the control of expression of the homeobox gene Msx-1 in the developing limb and face. Development 119:41-48
4. Catron KM, Iler N, Abate C (1993) Nucleotides flanking a conserved TAAT core dictate the DNA binding specificity of three murine homeodomain proteins. Mol Cell Biol 13:2354-2365
5. Catron KM, Wang H, Hu G, Shen MM, Abate-Shen C (1996) Comparison of Msx1 and Msx2 suggests a molecular basis for functional redundancy. Mech Dev 55:185-199
6. Catron KM, Zhang H, Marshall SC, Inostroza JA, Wilson JM, Abate C (1995) Transcriptional repression by Msx-1 does not require homeodomain DNA-binding sites. Mol Cell Biol 15:861-871
7. Chan-Thomas PS, Thompson RP, Robert B, Yacoub MH, Barton PJR (1993) Expression of homeobox genes Msx-1 (Hox-7) and Msx-2 (Hox-8) during cardiac development in the chick. Dev Dyn 197:203-216
8. Cleary MA, Stern S, Tanaka M, Herr W (1993) Differential positive control by Oct-1 and Oct-2: activation of a transcriptionally silent motif through Oct-1 and VP16 corecruitment. Genes Dev 7:72-83
9. Davidson D (1995) The function and evolution of Msx genes: pointers and paradoxes. Trends Genet 11:405-411
10. Dawid IB, Toyama R, Taira M (1995) LIM domain proteins. Crit Rev Acad Sci (Paris) 318:295-306
11. Feuerstein R, Wang X, Song D, Cooke NE, Liebhaber SA (1994) The LIM/double zinc-finger motif functions as a protein dimerization domain. Proc Natl Acad Sci (USA) 91:10655-10659
12. Freyd G, Kim SK, Horvitz HR (1990) Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-11. Nature 344:876-879
13. Iler N, Rowitch DH, Echelard Y, McMahon AP, Abate-Shen C (1995) A single homeodomain binding site restricts spatial expression of Wnt-1 in the developing brain. Dev Dyn 53:87-96
14. Johnson AD (1992) A combinatorial regulatory circuit in yeast. In: Yamamoto K, McKnight S (eds) Transcriptional Regulation. Cold Spring Harbor Press, New York, pp 975-1006
15. Johnson RL, Tabin CJ (1997) Molecular models for vertebrate limb development. Cell 90:979-990
16. Jowett AK, Vainio S, Ferguson MW, Sharpe PT, Thesleff I (1993) Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth. Development 117:461-470
17. Karlsson O, Thor S, Norberg T, Ohlsson H, Edlund T (1990) Insulin gene enhancer binding protein Isl-1 is a member of a novel class of proteins containing both a homeo- and a Cys-His domain. Nature 344:879-882
18. Kessel M, Gruss P (1990) Murine developmental control genes. Science 249:374-379
19. Krumlauf R (1994) Hox genes in vertebrate development. Cell 78:191-201
20. Lai J-S, Herr W (1992) Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. Proc Natl Acad Sci (USA) 89:6958-6962
21. Mann RS, Chan S-K (1996) Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins. Trends Genet 12:258-262
22. Roberson MS, Schoderbek WE, Tremml G, Maurer RA (1994) Activation of the glycoprotein hormone α-subunit promoter by a LIM-homeodomain transcription factor. Mol Cell Biol 14:2985-2993
23. Sánchez-García I, Rabbitts TH (1994) The LIM domain: a new structural motif found in zinc-finger-like proteins. Trends Genet 10:315-318
24. Satokata I, Maas R (1994) Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development. Nature Genet 6:348-355
25. Schmeichel KL, Beckerle MC (1994) The LIM domain is a modular protein-binding interface. Cell 79:211-219
26. Simon HG, Nelson C, Goff D, Laufer E, Morgan BA, Tabin C (1995) Differential expression of myogenic regulatory genes and msx1 during dedifferentiation and redifferentiation of regenerating amphibian limbs. Dev Dyn 202:1-12
27. Song K, Wang Y, Sassoon D (1992) Expression of Hox-7.1 in myoblasts inhibits terminal differentiation and induces cell transformation. Nature 360:477-481
28. Stein S, Fritsch R, Lemaire L, Kessel M (1996) Checklist: vertebrate homeobox genes. Mech Dev 55:91-108
29. Taira M, Evrard J-L, Steinmetz A, Dawid IB (1995) Classification of LIM proteins. Trends Genet 11:431-432
30. Wang Y, Sassoon D (1995) Ectoderm-mesenchyme and mesenchyme-mesenchyme interactions regulate Msx-1 expression and cellular differentiation in the murine limb bud. Dev Biol 168:374-382
31. Way JC, Chalfie M (1988) mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegans. Cell 54:5-16
32. Woloshin P, Song K, Degnin C, Killary AM, Goldhamer DJ, Sassoon D, Thayer MJ (1995) MSX1 inhibits MyoD expression in fibroblast x 10T1/2 cell hybrids. Cell 82:611-620
33. Wu L, Wu H, Sangiorgi F, Wu N, Bell JR, Lyons GE, Maxson R (1997) Miz1, a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA. Mech Dev 65:3-17
34. Xue D, Tu Y, Chalfie M (1993) Cooperative interactions between the Caenorhabditis elegans homeoproteins UNC-86 and MEC-3. Science 261:1324-1328
35. Zappavigna V, Sartori D, Mavilio F (1994) Specificity of HOX protein function depends on DNA-protein and protein-protein interactions, both mediated by the homeodomain. Genes Dev 8:732-744
36. Zhang H, Catron KM, Abate-Shen C (1996) A role for the Msx-1 homeodomain in transcriptional regulation: residues in the N-terminal arm mediate TATA binding protein interaction and transcriptional repression. Proc Natl Acad Sci (USA) 93:1764-1769
37. Zhang H, Hu G, Wang H, Sciavolino P, Iler N, Shen MM, Abate-Shen C (1997) Heterodimerization of Msx and Dlx homeoproteins results in functional antagonism. Mol Cell Biol 17:2920-2932