Inhibition by 1@?-acetoxychavicol acetate of lipopolysaccharide- and interferon-γ-induced nitric oxide production through suppression of inducible nitric oxide synthase gene expression in RAW264 cells

Carcinogenesis

Volumn 19, Issue 6, 1998, Pages 1007-1012

  Ohata, Takeji ^a,d   Fukuda, Kazunori ^a   Murakami, Akira ^b   Ohigashi, Hajime ^c   Sugimura, Takashi ^a   Wakabayashi, Keiji ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b KINKI UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d ASTELLAS PHARMA INC   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID DERIVATIVE; ANTINEOPLASTIC AGENT; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL DAMAGE; CONTROLLED STUDY; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTICARCINOGENIC AGENTS; CELL LINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RNA, MESSENGER; TERPENES; TRANSCRIPTION FACTORS;

EID: 0031878392     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/19.6.1007     Document Type: Article

References (44)

1. Kondo,A., Ohigashi,H., Murakami,A., Suratwadee,J. and Koshimizu,K. (1993) 1′ -Acetoxychavicol acetate as a potent inhibitor of tumor promoter-induced Epstein-Barr virus activation from Languas galanga, a traditional Thai condiment. Biosci. Biotechnol. Biachem., 57, 1344-1345.
2. Murakami,A., Ohura,S., Nakamura,Y., Koshimizu,K. and Ohigashi,H (1996) 1′ -Acetoxychavicol acetate, a Superoxide anion generation inhibitor, potently inhibits tumor promotion by 12-O-tetradecanoylphorbol-13-acetate in ICR mouse skin. Oncology, 53, 386-391.
3. Ohnishi,M. et al. (1996) Chemopreventive effect of a xanthine oxidase inhibitor, 1′ -acetoxychavicol acetate, on rat oral carcinogenesis. Jpn. J. Cancer Res., 87, 349-356.
4. Tanaka,T. et al. (1997) A xanthine oxidase inhibitor 1'-acetoxychavicol acetate inhibits azoxymethane-induced colonie aberrant crypt foci in rats. Carcinogenesis, 18, 1113-1118.
5. Tanaka,T. et al. (1997) Chemoprevention of azoxymethane-induced rat colon carcinogenesis by a xanthine oxidase inhibitor, 1'-acetoxychavicol acetate. Jpn. J. Cancer Res., 88, 821-830.
6. Noro,T., Sekiya,T., Katoh (née Abe),M., Oda,Y., Miyase,T., Kuroyanagi,M., Ueno,A. and Fukushima,S. (1988) Inhibitors of xanthine oxidase from Alpinia galanga. Chem. Pharm. Bull., 36, 244-248.
7. Pence,C.B. and Reiners,J.J.,Jr (1987) Murine epidermal xanthine oxidase activity: correlation with degree of hyperplasia induced by tumor promoters. Cancer Res., 47, 6388-6392.
8. Wink,D.A. et al. (1991) DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. Science, 254, 1001-1003.
9. Liu,R.H., Jacob,J.R., Hotchkiss,J.H., Cote,P.J., Gerin,J.L. and Tennant,B.C. (1994) Woodchuck hepatitis virus surface antigen induces nitric oxide synthesis in hepatocytes: possible role in hepatocarcinogenesis. Carcinogenesis, 15, 2875-2877.
10. Ohshima,H. and Bartsch,H. (1994) Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis. Mutat. Res., 305, 253-264.
11. Haswell-Elkins,M.R., Satarug,S., Tsuda,M., Mairiang,E., Esumi,H., Sithithaworn,P., Mairiang,P., Saitoh,M., Yongvanit,P. and Elkins,D.B. (1994) Liver fluke infection and cholangiocarcinoma: model of endogenous nitric oxide and extragastric nitrosation in human carcinogenesis. Mutat. Res., 305, 241-252.
12. Nathan,C. (1992) Nitric oxide as a secretory product of mammalian cells. FASEB J., 6, 3051-3064.
13. Moncada,S., Palmer,R.M.J. and Higgs,E.A. (1991) Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev., 43, 109-142.
14. Wei,X.-q. et al. (1995) Altered immune response in mice lacking inducible nitric oxide synthase. Nature, 375. 408-411.
15. Farias-Eisner,R., Sherman,M.P., Aeberhard,E. and Chaudhuri,G. (1994) Nitric oxide is an important mediator for tumoricidal activity in vivo. Proc. Natl Acad. Sci. USA, 91, 9407-9411.
16. Stadler,J., Billiar.T.R., Curran,R.D., Stuehr,D.J., Ochoa,J.B. and Simmons, R.L. (1991) Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes. Am. J. Physiol., 260, C910-C916.
17. Kwon,N.S., Stuehr,D.J. and Nathan,C.F. (1991) Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide. J. Exp. Med., 174, 761-767.
18. Xia,Y. and Zweier,J.L. (1997) Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages. Proc. Natl Acad. Sci. USA, 94, 6954-6958.
19. Beckman,J.S., Beckman,T.W., Chen,J., Marshall,P.A. and Freeman,B.A. (1990) Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and Superoxide. Proc. Natl Acad. Sci. USA, 87, 1620-1624.
20. Denicola,A., Rubbo,H., Rodriguez,D. and Radi,R. (1993) Peroxynitrite-mediated cytotoxicity to Trypanosoma cruzi. Arch. Biochem. Biophys., 304, 279-286.
21. Miller,M.J.S. et al. (1995) Role of inducible nitric oxide synthase expression and peroxynitrite formation in Guinea pig ileitis. Gastroenterology, 109, 1475-1483.
22. Yermilov,V., Rubio,J., Becchi,M., Friesen,M.D., Pignatelli,B. and Oshima,H. (1995) Formation of 8-nitroguanine by the reaction of guanine with peroxynitrite in vitro. Carcinogenesis, 16, 2045-2050.
23. Mitsui,S., Kobayashi,S., Nagahori,H. and Ogiso,A. (1976) Constituents from seeds of Alpinia galanga Wild, and their anti-ulcer activities. Chem. Pharm. Bull., 24, 2377-2382.
24. 15N]nitrate in biological fluids. Anal. Biochem., 126, 131-138.
25. Schreck,R. and Baeuerle,P.A. (1994) Assessing oxygen radicals as mediators in activation of inducible cukaryotic transcription factor NF-κB. Methods Enzymol., 234, 151-163.
26. Bradford,M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem., 72, 248-254.
27. Ohata,T., Fukuda,K., Takahushi,M., Sugimura,T. and Wakabayashi,K. (1997) Suppression of nitric oxide production in lipopolysaccharide-stimulated macrophage cells by ω3 polyunsaturated fatty acids. Jpn. J. Cancer Res., 88, 234-237.
28. Brouet,I. and Oshima,H. (1995) Curcumin, an anti-tumour promoter and anti-inflammatory agent, inhibits induction of nitric oxide synthase in activated macrophages. Biochem. Biophys. Res. Commun., 206, 533-540.
29. Dong,Z., Qi,X., Xie,K. and Fidler,I.J. (1993) Protein tyrosine kinase inhibitors decrease induction of nitric oxide synthase activity in lipopolysaccharide-responsive and lipopolysaccharide-nonresponsive murine macrophages. J. Immunol., 151, 2717-2724.
30. Xie,Q.-w., Whisnant,R. and Nathan,C. (1993) Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon γ and bacterial lipopolysaccharide. J. Exp. Med., 177, 1779-1784.
31. Xie,Q.-w., Kashiwabara,Y. and Nathan,C. (1994) Role of transcription factor NF-κB/Rel in induction of nitric oxide synthase. J. Biol. Chem., 269, 4705-4708.
32. Gao,J., Morrison,D.C., Parmely,T.J., Russell,S.W. and Murphy,W.J. (1997) An interferon-γ-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-γ and lipopolysaccharide. J. Biol. Chem., 272, 1226-1230.
33. Kamijo,R. et al. (1994) Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science, 263, 1612-1615.
34. Goldring,C.E.P, Reveneau,S., Algarté.M. and Jeannin,J.-F. (1996) In vivo footprinting of the mouse inducible nitric oxide synthase gene: inducible protein occupation of numerous sites including Oct and NF-IL6. Nucleic Acids Res., 24, 1682-1687.
35. Melillo,G.M., Musso,T. Sica,A., Taylor,L.S., Cox,G.W. and Varesio,L. (1995) A hypoxia-responsive element mediates a novel pathway of activation of the inducible nitric oxide synthase promoter. J. Exp. Med., 182, 1683-1693.
36. Epstein,F.H. (1997) Nuclear factor-κB - a pivotal transcription factor in chronic inflammatory diseases. New Engl. J. Med., 336, 1066-1071.
37. Siebenlist,U., Franzoso,G. and Brown,K. (1994) Structure, regulation and function of NF-κB. Annu. Rev. Cell Biol., 10, 405-455.
38. Henkel,T., Machleidt,T., Alkalay,I., Krönke,M., Ben-Neriah,Y. and Baeuerle,P.A. (1993) Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB. Nature, 365, 182-185.
39. Brown,K., Gerstberger,S., Carlson,L., Franzoso,G. and Siebenlist,U. (1995) Control of IκB-α proteolysis by site-specific, signal-induced phosphorylation. Science, 267, 1485-1488.
40. Chen,F., Kuhn,D.C., Gaydos,L.J. and Demers,L.M. (1996) Induction of nitric oxide and nitric oxide synthase mRNA by silica and lipopolysaccharide in PMA-primed THP-1 cells. APMIS, 104, 176-182.
41. Angel,P. and Karin,M. (1991) The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta, 1072, 129-157.
42. Karin,M. (1995) The regulation of AP-1 activity by mitogen-activated protein kinases. J. Biol. Chem., 270, 16483-16486.
43. Schindler,C and Darnell,J.E.,Jr (1995) Transcriptional responses to polypeptide ligands: the JAK-Stat pathway. Annu. Rev. Biochem., 64, 621-651.
44. Sun,Y. and Oberley,L.W. (1996) Redox regulation of transcriptional activators. Free Radical Biol. Med., 21, 335-348.