Effects of hypoxaemia on foetal heart rate, variability and cardiac rhythm

Clinical and Experimental Pharmacology and Physiology

Volumn 25, Issue 7-8, 1998, Pages 577-584

  Yu, Ze Yan ^a   Lumbers, Eugenie R ^a   Gibson, Karen J ^a   Stevens, Andrew D ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Foetus; Heart rate variability; Hypoxaemia

Indexed keywords

ATROPINE; CATECHOLAMINE DERIVATIVE; PROPRANOLOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRADYCARDIA; CONTROLLED STUDY; FEMALE; FETUS; FETUS HEART RATE; HEART OUTPUT; HEART RATE VARIABILITY; HYPOXEMIA; MEAN ARTERIAL PRESSURE; NONHUMAN; POWER SPECTRUM; SHEEP; SYMPATHETIC TONE; VAGUS NERVE STIMULATION;

EID: 0031876662     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.1998.tb02255.x     Document Type: Article

References (27)

1. Segar JL, Merrill DC, Smith BA, Robillard JE. Role of sympathetic activity in the generation of heart rate and arterial pressure variability in fetal sheep. Pediatr. Res. 1994; 35: 250-4.
2. Walker AM, Cannata JP, Dowling MH, Ritchie BC, Maloney JE. Age-dependent pattern of autonomic heart rate control during hypoxia in fetal and newborn lambs. Biol. Neonate 1979; 35: 198-208.
3. Wood CE. Baroreflex and chemoreflex control of fetal hormone secretion. Reprod. Fertil. Dev. 1995; 7: 479-89.
4. Gunn TR, Johnston BM, Iwamoto HS, Fraser M, Nicholls MG, Gluckman PD. Haemodynamic and catecholamine responses to hypothermia in the fetal sheep in utero. J. Dev. Physiol. 1985; 7: 241-9.
5. Jones CT, Ritchie JWK. The effect of adrenergic blockade on fetal response to hypoxia. J. Dev. Physiol. 1983; 5: 211-22.
6. Malliani A, Pagani M, Lombardi F, Cerutti S. Cardiovascular neural regulation explored in the frequency domain. Circulation 1991; 84: 482-92.
7. Lumbers ER, Stevens AD. Changes in fetal renal function in response to infusions of a hyperosmotic solution of mannitol to the ewe. J. Physiol. 1983; 343: 439-46.
8. Ismay MJ, Lumbers ER, Stevens AD. The action of angiotensin II on the baroreflex response of the conscious ewe and the conscious foetus. J. Physiol. 1979; 288: 467-79.
9. Zar JH. Biostatistical Analysis, 2nd edn. Prentice-Hall, Englewood Cliffs, New Jersey. 1984; 162-205.
10. Akselrod S, Gordon D, Ubel FA, Shannon DC, Barger AC, Cohen RJ. Power spectral analysis of heart rate fluctuations: A quantitative probe of beat-to-beat cardiovascular control. Science 1981; 213: 220-2.
11. Gibson KJ, Lumbers ER. The roles of arginine vasopressin in fetal sodium balance and as a mediator of the effects of fetal 'stress'. J. Dev. Physiol. 1993; 19: 125-36.
12. Daffonchio A, Franzelli C, Radaelli A. et al. Sympathectomy and cardiovascular spectral components in conscious normotensive rats. Hypertension 1995; 25: 1287-93.
13. Pariti G, Castiglioni P, Di Rienzo M, Omboni S, Pedotti A, Mancia G. Sequential spectral analysis of 24-hour blood pressure and PI in humans. Hypertension 1990; 16: 414-21.
14. Vapaavouri EK, Shinebourne EA, Williams RL, Heymann MA, Rudolph AM. Development of cardiovascular responses to autonomic blockade in intact fetal and neonatal lambs. Biol. Neonate 1973; 22: 177-88.
15. Siimes ASI, Välimäki ITA, Antila KJ et al. Regulation of heart rate variation by the autonomic nervous system in neonatal lambs. Pediatr. Res. 1990; 27: 383-91.
16. Walker AM, Cannata JP, Dowling MH, Ritchie BC, Maloney JE. Sympathetic and parasympathetic control of heart rate in unanaesthetized fetal and newborn lambs. Biol. Neonate 1978; 33: 135-43.
17. Giussani DA, Spencer JAD, Moore PJ, Bennet L, Hanson MA. Afferent and efferent components of the cardiovascular reflex responses to acute hypoxia in term fetal sheep. J. Physiol. 1993; 461: 431-49.
18. Sameshima H, Koos BJ. Effects of moderate hypoxia on fetal electrocortical activity, eye movements, and breathing activity in sheep. J. Dev. Physiol. 1986; 8: 411-19.
19. McMullen JR. The effects of hypoxia, noradrenaline infusion and sympathetic nerve stimulation on fetal renal function. BSc (Hons) thesis, University of NSW, NSW, Australia. 1995.
20. Dalton KJ, Dawes GS, Patrick JE. Diurnal, respiratory, and other rhythms of fetal heart rate in lambs. Am. J. Obstet. Gynecol. 1977; 127: 414-24.
21. Parer JT. The effects of acute maternal hypoxia on fetal oxygenation and the umbilical circulation in the sheep. Eur. J. Obstet. Gynecol. Reprod. Biol. 1980; 10: 125-36.
22. Thaler I, Timor-Tritsch IE, Blumenfeld Z. Effect of acute hypoxia on human fetal heart rate. Acta Obstet. Gynecol. Scand. 1985; 64: 47-50.
23. Blanco CE, Dawes GS, Hanson MA, McCooke HB. The response to hypoxia of arterial chemoreceptors in fetal sheep and newborn lambs. J. Physiol. 1984; 351: 25-37.
24. Smith JH, Anand KJS, Cotes PM et al. Antenatal fetal heart rate variation in relation to the respiratory and metabolic status of the compromised human foetus. Br. J. Obstet. Gynaecol. 1988; 95: 980-9.
25. Martin CR. Regulation of the fetal heart rate and genesis of FHR patterns. Semin. Perinatol. 1978; 2: 131-46.
26. Lindecrantz K, Cerutti S, Civardi S et al. Power spectrum analysis of the fetal heart rate during noradrenaline infusion and acute hypoxaemia in the chronic fetal lamb preparation. Int. J. Biomed. Comput. 1993; 33: 199-207.
27. Stevens AD, Lumbers ER. Effects of reduced uterine blood flow on fetal cardiovascular, renal, and lung function. Am. J. Physiol. 1990; 259: R1004-11.