Chloroquine in Africa: Critical assessment and recommendations for monitoring and evaluating chloroquine therapy efficacy in sub-Saharan Africa

Tropical Medicine and International Health

Volumn 3, Issue 7, 1998, Pages 543-552

  Bloland, P B ^a,e   Kazembe, P N ^b   Oloo, A J ^c   Himonga, B ^d   Barat, L M ^a   Ruebush, T K ^a  

^a CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^b MINISTRY OF HEALTH   (Malawi)

^c KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^d MINISTRY OF HEALTH   (Zambia)

^e NATL CENTER FOR INFECTIOUS DISEASES   (United States)

Author keywords

Africa; Chloroquine; Drug policy; Drug resistance; Malaria; Treatment

Indexed keywords

ANTIMALARIAL AGENT; CHLOROQUINE; FANSIDAR;

CHLOROQUINE; DISEASE CONTROL; DRUG PRESCRIBING; MALARIA;

AFRICA; ARTICLE; CHILD; DEVELOPING COUNTRY; DRUG EFFICACY; DRUG MONITORING; FEMALE; HEALTH CARE POLICY; HUMAN; INFECTION CONTROL; MAJOR CLINICAL STUDY; MALARIA; MALARIA CONTROL; MALE; MEDICAL DECISION MAKING; ORAL DRUG ADMINISTRATION; PLASMODIUM FALCIPARUM; TREATMENT FAILURE; TREATMENT OUTCOME;

ANTIMALARIALS; CHILD, PRESCHOOL; CHLOROQUINE; DRUG COMBINATIONS; DRUG MONITORING; DRUG RESISTANCE; FEMALE; HUMANS; INFANT; KENYA; MALARIA, FALCIPARUM; MALAWI; MALE; PARASITEMIA; PYRIMETHAMINE; SULFADOXINE; TIME FACTORS; TREATMENT FAILURE; ZAMBIA;

AFRICA, (SUB-SAHARA);

EID: 0031876170     PISSN: 13602276     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3156.1998.00270.x     Document Type: Article

References (19)

1. Barat L, Himonga B, Nkunika S et al. (1998) A systematic approach to the development of a rational malaria treatment policy in Zambia. Tropical Medicine and International Health 3, 535-542.
2. Bloland PB, Lackritz EM, Kazembe PN et al. (1993) Beyond chloroquine: implications of drug resistance for evaluating malaria therapy efficacy and treatment policy in Africa. Journal of Infectious Diseases 167, 932-937.
3. Brinkmann U & Brinkmann A (1991) Malaria and health in Africa: the present situation and epidemiological trends. Tropical Medicine and Parasitology 42, 204-213.
4. Khoromana CO, Campbell CC, Wirima JJ & Heymann DL (1986) In vivo efficacy of chloroquine treatment for Plasmodium falciparum in Malawian children under five years of age. American Journal of Tropical Medicine and Hygiene 35, 465-471.
5. Mount DL, Nahlen BL, Patchen LC & Churchill FC (1989) Adaptations of the Saker-Solomons test: simple, reliable colorimetric field assays for chloroquine and its metabolites in urine. Bulletin of the World Health Organization 67, 295-300.
6. Ohrt C, Mirabelli-Primdahl L, Karnasuta C, Chantakulkij S & Kain K (1997) Distinguishing Plasmodium falciparum treatment failures from reinfections by restriction fragment length polymorphism and polymerase chain reaction genotyping. American Journal of Tropical Medicine and Hygiene 57, 430-437.
7. Paluku KM, Breman JG, Moore M et al. (1988) Response of children with Plasmodium falciparum to chloroquine and development of a national malaria treatment policy in Zaire. Transactions of the Royal Society of Tropical Medicine and Hygiene 82, 353-357.
8. Rothman KJ (1986) Modern Epidemotology, Little, Brown and Company, Boston/Toronto.
9. SAS Institute Inc. (1989) SAS/STAT User's Guide, Version 6, SAS Institute, Inc., Cary, NC.
10. Schapira A, Almeida Franco LT, Averkiev L et al. (1988) The Plasmodium falciparum chloroquine in vivo test: extended follow-up is more important than parasite counting. Transactions of the Royal Society of Tropical Medicine and Hygiene 82, 39-43.
11. Sehapira A, Beales PF & Holloran ME (1993) Malaria: Living with drug resistance. Parasitology Today 9, 168-174.
12. Sudre P, Breman JG, McFarland D & Koplan JP (1992) Treatment of chloroquine-resistant malaria in African children: a cost-effectiveness analysis. International Journal of Epidemiology 21, 146-154.
13. Warsame M, Wernsdorfer WH, Ericsson Ö & Björkman A (1990) Isolated malaria outbreak in Somalia: role of chloroquine-resistant Plasmodium falciparum demonstrated in Balead epidemic, Journal of Tropical Medicine and Hygiene 93, 284-289.
14. Wernsdorfer WH (1994) Epidemiology of drug resistance in malaria. Acta Tropica 56, 143-156.
15. World Health Organization (1986) Chemotherapy of malaria, 2nd edn. (ed. LJ Bruce-Chwatt), World Health Organization, Geneva.
16. World Health Organization (1993) A global strategy for malaria control. World Health Organization, Geneva.
17. World Health Organization (1994) Antimalarial drug policies: Data requirements, treatment of uncomplicated malaria and management of malaria in pregnancy. Report of an Informal Consultation, Geneva, 1994. WHO/MAL/94.1070, World Health Organization, Geneva.
18. World Health Organization (1996) World malaria situation in 1993, part L Weekly Epidemiological Record 71, 17-22.
19. Zucker JR, Lackritz EM, Ruebush TK et al. (1996) Childhood mortality during and after hospitalization in western Kenya - effect of malaria treatment regimens. American Journal of Tropical Medicine and Hygtene 55, 655-660.