Serotonin, serotonergic receptors, selective serotonin reuptake inhibitors and sexual behaviour

International Clinical Psychopharmacology

Volumn 13, Issue SUPPL. 6, 1998, Pages

  Olivier, B ^a,b   Van Oorschot, R ^b   Waldinger, M D ^a,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b Solvay Pharmaceuticals Inc   (Netherlands)

^c LEYENBURG HOSPITAL   (Netherlands)

Author keywords

Fluvoxamine; Pharmacology; Selective serotonin uptake inhibitors; Serotonin; Serotonin receptors; Sexual function

Indexed keywords

CLOMIPRAMINE; FLUOXETINE; FLUVOXAMINE; PAROXETINE; RECEPTOR SUBTYPE; SEROTONIN RECEPTOR; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; ZIMELDINE;

ANIMAL EXPERIMENT; ARTICLE; AVOIDANCE BEHAVIOR; EJACULATION; HUMAN; MOUSE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; SEROTONINERGIC SYSTEM; SEXUAL BEHAVIOR; SEXUAL FUNCTION; TASTE AVERSION;

EID: 0031875943     PISSN: 02681315     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004850-199807006-00003     Document Type: Article

References (27)

1. Adell A, Artigas F (1991). Differential effects of clomipramine given locally or systemically on extracellular 5-hydroxytryptamine in raphe nuclei and frontal cortex. An in vivo brain microdialysis study. Naunyn Schmiedebergs Arch Pharmacol 343:237-244.
2. Ahlenius S, Larsson K, Svensson L, Hjorth S, Carlsson A, Lindberg P, et al. (1981). Effects of anew type of 5-HT receptor agonist on male rat sexual behavior. Pharmacol Biochem Behav 15:785-792.
3. Bell N, Artigas F (1992). Fluvoxamine increases preferentially extracellular 5-hydroxy-tryptamine in the raphe nuclei: an in vivo microdialysis study. Eur J Pharmacol 229:101-103.
4. Berendsen HHG, Broekkamp CLE (1990). Behavioural evidence for functional interactions between 5-HT receptor subtypes in rats and mice. Br J Pharmacol 101:667-673.
5. Berendsen HHG, Broekkamp CLE (1994). Comparison of stimulus properties of fluoxetine and 5-HT receptor agonists in a conditioned taste aversion procedure. Eur J Pharmacol 253:83-89.
6. 1D receptor messenger RNA and ligand binding sites in guinea-pig brain and trigeminal ganglion: clues for function. Neuroscience 82:469-484.
7. 3H]-paroxetine binding sites in rat brain. J Pharmacol Toxicol Methods 27:209-216.
8. 3H]-imipramine. J Pharmacol Exp Ther 242:364-371.
9. 1A receptor agonist 8-OH-DPAT. Psychopharmacology 112:121-128.
10. 7 receptors. In: Serotonin Receptors and their Ligands. Pharmacochemistry Library Volume 27 (Olivier B, van Wijngaarden I, Soudijn W, eds), Amsterdam: Elsevier Science B.V. pp. 311-323.
11. 4 receptor: use of a novel antagonist. Br J Pharmacol 108:618-624.
12. Haensel SM, Rowland DL, Kallan KTHK, Slob AK (1996). Clomipramine and sexual function in men with premature ejaculation and controls. J Urol 156:1310-1315.
13. Hoffman B (1993). Molecular biology of serotonin uptake sites. In: Serotonin - From Cell Biology to Pharmacology and Therapeutics (Vanhoutte PM, Saxena PR, Paoletti R, Brunello N, Jackson AS, eds), Dordrecht: Kluwer Academic, pp. 9-19.
14. 3H]-imipramine localization and relationship to serotonin transporter. J Pharmacol Exp Ther 252:410-418.
15. 1A receptor. Eur J Neurosci 214 (suppl. 2):121.
16. Mos J, Olivier B, Bloetjes K, Poth M (1990). Drug-induced facilitation of sexual behaviour in the male rat: behavioural and pharmacological aspects. In: Psychoneuro-Endocrinology of Growth and Development (Slob AK, Baum MJ, eds), Rotterdam: Medicom. pp. 221-232.
17. Mos J, Van Logten J, Bloetjes K, Olivier B (1991). The effects of idazoxan and 8-OH-DPAT on sexual behaviour and post-ejaculatory vocalizations in the rat. Neurosci Biobehav Rev 15:505-510.
18. Mos J, Mollet I, Tolboom JTBM, van Oorschot R, Waldinger MD, Olivier B (in press). Selective serotonin reuptake inhibitors (SSRIs) and sexual behaviour of the male rat: a comparative study. Eur Neuropsychopharmacol.
19. Olivier B, Mos J (1988). Effects of psychotropic drugs on sexual behaviour in male rats. In: Depression, Anxiety and Aggression - Preclinical and Clinical Interfaces (Swinkels JA, Blijleven W, eds), Houten: Medidact. pp. 121-133.
20. Olivier B, Bosch L, van Hest A, van der Heyden J, Mos J, van der Poel G, et al. (1993). Preclinical evidence on the psychotropic profile of fluvoxamine. Pharmacopsychiatry 26:2-9.
21. Palacios JM, Waeber C, Hoyer D, Mengod O (1990). Distribution of serotonin receptors. Ann N Y Acad Sci 600:36-52.
22. 1D receptor family. EMBO J 11:4779-4786.
23. Szele FG, Murphy DL, Garrick NA (1988). Effects of fenfluramine, m-chlorophenyl piperazine and other serotonin-related agonists and antagonists on penile erections in non-human primates. Life Sci 43:1297-1303.
24. Törk I (1990). Anatomy of the serotonergic system. Ann NY Acad Sci 600:9-35.
25. Waldinger MD, Hengeveld MW, Zwinderman AH (1994). Paroxetine treatment of premature ejaculation: a double-blind, randomised, placebo-controlled study. Am J Psychiatry 151:1377-1379.
26. Waldinger MD, Hengeveld MW, Zwinderman AH (1997). Ejaculation-retarding properties of paroxetine in patients with primary premature ejaculation: a double-blind, randomised, dose-response study. Br J Urology 79:592-595.
27. Waldinger MD, Hengeveld MW, Zwinderman AH, Olivier B (1998). Effects of SSRI antidepressants on ejaculation: a double-blind, randomised, placebo-controlled study with fluoxetine, fluvoxamine, paroxetine and sertraline. J Clin Psychopharmacol 18:274-281.