-
1
-
-
0025679116
-
Role of endocytosis in the action of ether lipids on WEHI-3B, HL-60 and FCDP-mix A4 cells
-
Bazill GW, Dexter TM (1990) Role of endocytosis in the action of ether lipids on WEHI-3B, HL-60 and FCDP-mix A4 cells. Cancer Res 50: 7505-7512
-
(1990)
Cancer Res
, vol.50
, pp. 7505-7512
-
-
Bazill, G.W.1
Dexter, T.M.2
-
2
-
-
0002165941
-
Synthetic alkylphospholipid analogs: A new class of antitumor agents
-
Kuo JF (ed) CRC Press, Boca Raton
-
Berdel WE, Andreesen R, Munder PG (1985). Synthetic alkylphospholipid analogs: a new class of antitumor agents. In: Kuo JF (ed) Phospholipids and cellular regulation, vol 2. CRC Press, Boca Raton, pp 41-73
-
(1985)
Phospholipids and Cellular Regulation
, vol.2
, pp. 41-73
-
-
Berdel, W.E.1
Andreesen, R.2
Munder, P.G.3
-
3
-
-
0026690152
-
Alkyl-lysophospholipid purging for autologous bone marrow transplantation in acute leukemia in second or subsequent remission after extramedullary relapse
-
Berdel WE, Vogler WR, Olson AC (1992) Alkyl-lysophospholipid purging for autologous bone marrow transplantation in acute leukemia in second or subsequent remission after extramedullary relapse. Progr Clin Biol Res 377: 79-85
-
(1992)
Progr Clin Biol Res
, vol.377
, pp. 79-85
-
-
Berdel, W.E.1
Vogler, W.R.2
Olson, A.C.3
-
4
-
-
0027817270
-
Inhibition of the signalling enzyme phosphatidylinositol-3-kinase by antitumor ether lipid analogues
-
Berggren MI, Gallegos A, Dressier LA, Modest EJ, Powis G (1993) Inhibition of the signalling enzyme phosphatidylinositol-3-kinase by antitumor ether lipid analogues. Cancer Res 53:4297-4302
-
(1993)
Cancer Res
, vol.53
, pp. 4297-4302
-
-
Berggren, M.I.1
Gallegos, A.2
Dressier, L.A.3
Modest, E.J.4
Powis, G.5
-
5
-
-
0028189803
-
Protein kinase C in signal transduction and carcinogenesis
-
Blumberg PM, Acs G, Areces LB, Kazanaietz MG, Lewing NE, Szallasi Z (1994) Protein kinase C in signal transduction and carcinogenesis. Progress in Clinical and Biological Research 387: 3-19
-
(1994)
Progress in Clinical and Biological Research
, vol.387
, pp. 3-19
-
-
Blumberg, P.M.1
Acs, G.2
Areces, L.B.3
Kazanaietz, M.G.4
Lewing, N.E.5
Szallasi, Z.6
-
6
-
-
0028670129
-
Regulation of protein kinase C and its role in cancer biology
-
Blumberg PM, Acs G, Hannun YA (1994) Regulation of protein kinase C and its role in cancer biology. Cancer and Metastasis Rev 13: 411-431
-
(1994)
Cancer and Metastasis Rev
, vol.13
, pp. 411-431
-
-
Blumberg, P.M.1
Acs, G.2
Hannun, Y.A.3
-
7
-
-
0028987154
-
Lysophosphatidylcholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step
-
Boggs K, Rock C, Jackowski S (1995) Lysophosphatidylcholine and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step. J Biol Chem 270: 7757-7764
-
(1995)
J Biol Chem
, vol.270
, pp. 7757-7764
-
-
Boggs, K.1
Rock, C.2
Jackowski, S.3
-
8
-
-
0029019501
-
Lysophosphatidylcholine attenuates the cytotoxic effects of the antineoplastic phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine
-
Boggs K, Rock C, Jackowski S (1995) Lysophosphatidylcholine attenuates the cytotoxic effects of the antineoplastic phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine. J Biol Chem 270: 11612-11618
-
(1995)
J Biol Chem
, vol.270
, pp. 11612-11618
-
-
Boggs, K.1
Rock, C.2
Jackowski, S.3
-
9
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein using the principle of protein-dye binding
-
Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein using the principle of protein-dye binding. Anal Biochem 72: 248-254
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
11
-
-
0000503498
-
Ether lipids in experimental cancer chemotherapy
-
Hickman JA, Tritton TR (eds) Blackwell, Oxford
-
Daniel LW (1991) Ether lipids in experimental cancer chemotherapy. In: Hickman JA, Tritton TR (eds) Cancer chemotherapy. Blackwell, Oxford, p 2-57
-
(1991)
Cancer Chemotherapy
, pp. 2-57
-
-
Daniel, L.W.1
-
12
-
-
0023503110
-
Ether lipids inhibit the effects of phorbol diester tumor promoters
-
Daniel LW, Etkin LA, Morrison BT, Parker J, Morris-Natschke S, Surles JR, Piantadosi C (1987) Ether lipids inhibit the effects of phorbol diester tumor promoters. Lipids 22: 851-855
-
(1987)
Lipids
, vol.22
, pp. 851-855
-
-
Daniel, L.W.1
Etkin, L.A.2
Morrison, B.T.3
Parker, J.4
Morris-Natschke, S.5
Surles, J.R.6
Piantadosi, C.7
-
13
-
-
0023851865
-
Alkyl-linked diglycerides inhibit protein kinase C activation by diacylglycerols
-
Daniel LW, Small GW, Schmitt JD (1988) Alkyl-linked diglycerides inhibit protein kinase C activation by diacylglycerols. Biophys Biochem Res Commun 151: 291-297
-
(1988)
Biophys Biochem Res Commun
, vol.151
, pp. 291-297
-
-
Daniel, L.W.1
Small, G.W.2
Schmitt, J.D.3
-
16
-
-
0021719170
-
Purging murine leukemic marrow with alkyllysophospholipids
-
Glasser L, Somberg LB, Vogler WR (1984) Purging murine leukemic marrow with alkyllysophospholipids. Blood 64: 1288-1291
-
(1984)
Blood
, vol.64
, pp. 1288-1291
-
-
Glasser, L.1
Somberg, L.B.2
Vogler, W.R.3
-
17
-
-
0027313540
-
Inhibition of phospholipase D by agents that inhibit cell growth
-
Gratas C, Powis G (1993) Inhibition of phospholipase D by agents that inhibit cell growth. Anticancer Res 13: 1239-1244
-
(1993)
Anticancer Res
, vol.13
, pp. 1239-1244
-
-
Gratas, C.1
Powis, G.2
-
18
-
-
0020645583
-
2+-dependent protein phosphorylation system in various types of leukemia cells from human patients and in human leukemic cell lines HL-60 and K562, and its inhibition by alkyl-lysophospholipid
-
2+-dependent protein phosphorylation system in various types of leukemia cells from human patients and in human leukemic cell lines HL-60 and K562, and its inhibition by alkyl-lysophospholipid. Cancer Res 43: 2955-2961
-
(1983)
Cancer Res
, vol.43
, pp. 2955-2961
-
-
Helfman, D.M.1
Barnes, K.C.2
Kinkade, J.M.3
Vogler, W.R.4
Shoji, M.5
Kuo, J.F.6
-
19
-
-
0023521343
-
Phase I trial of the thioether phospholipid analogue BM 41.440 in cancer patients
-
Herrmann DBJ, Neumann HA, Berdel WE, Heim ME, Fromm M, Boerner D, Bicker U (1988) Phase I trial of the thioether phospholipid analogue BM 41.440 in cancer patients. Lipids 11: 962-966
-
(1988)
Lipids
, vol.11
, pp. 962-966
-
-
Herrmann, D.B.J.1
Neumann, H.A.2
Berdel, W.E.3
Heim, M.E.4
Fromm, M.5
Boerner, D.6
Bicker, U.7
-
20
-
-
0023025477
-
Cytotoxicity and metabolism of alkyl phospholipid analogs in neoplastic cells
-
Hoffman DR, Hoffman LH, Snyder F. (1986) Cytotoxicity and metabolism of alkyl phospholipid analogs in neoplastic cells. Cancer Res 46: 5803-5809
-
(1986)
Cancer Res
, vol.46
, pp. 5803-5809
-
-
Hoffman, D.R.1
Hoffman, L.H.2
Snyder, F.3
-
22
-
-
0029812269
-
Chemopurging of peripheral blood-derived progenitor cells by alkyl-lysophospholipid and its effect on haematopoietic rescue after high-dose therapy
-
Koenigsmann MP, Notter M, Knauf WU, Papadimitriou CA, Oberg D, Reufi B, Mucke C, Thiel E, Berdel WE (1996) Chemopurging of peripheral blood-derived progenitor cells by alkyl-lysophospholipid and its effect on haematopoietic rescue after high-dose therapy. Bone Marrow Transplant 18: 549-557
-
(1996)
Bone Marrow Transplant
, vol.18
, pp. 549-557
-
-
Koenigsmann, M.P.1
Notter, M.2
Knauf, W.U.3
Papadimitriou, C.A.4
Oberg, D.5
Reufi, B.6
Mucke, C.7
Thiel, E.8
Berdel, W.E.9
-
23
-
-
0026678066
-
Hexadecylphosphocholine and octadecyl-methyl-glycero-3-phosphocholine: A comparison of activity, serum binding and tissue distribution
-
Kötting J, Marschner NW, Neumuhller W, Unger C, Eibl H (1992) Hexadecylphosphocholine and octadecyl-methyl-glycero-3-phosphocholine: a comparison of activity, serum binding and tissue distribution. Progr Exp Tumor Res 31:131-142
-
(1992)
Progr Exp Tumor Res
, vol.31
, pp. 131-142
-
-
Kötting, J.1
Marschner, N.W.2
Neumuhller, W.3
Unger, C.4
Eibl, H.5
-
24
-
-
0025233636
-
Synthesis and biological evaluation of novel quaternary ammonium derivatives of alkylglycerols as potent inhibitors of protein kinase C
-
Marasco CJ, Piantadosi C, Meyer KE, Morris-Natschke S, Ishaq K, Small GW, Daniel LW (1990) Synthesis and biological evaluation of novel quaternary ammonium derivatives of alkylglycerols as potent inhibitors of protein kinase C. J Med Chem 33: 985-992
-
(1990)
J Med Chem
, vol.33
, pp. 985-992
-
-
Marasco, C.J.1
Piantadosi, C.2
Meyer, K.E.3
Morris-Natschke, S.4
Ishaq, K.5
Small, G.W.6
Daniel, L.W.7
-
25
-
-
0029555305
-
Phase I trial of ilmofosine as a 24 hour infusion weekly
-
Mehren M von, Giantonio BJ, McAleer C, Schilder R, McPhillips J, O'Dwyer PJ (1995) Phase I trial of ilmofosine as a 24 hour infusion weekly. Invest New Drugs 13: 205-210
-
(1995)
Invest New Drugs
, vol.13
, pp. 205-210
-
-
Von Mehren, M.1
Giantonio, B.J.2
McAleer, C.3
Schilder, R.4
McPhillips, J.5
O'Dwyer, P.J.6
-
26
-
-
1842290345
-
3 (Edelfosine): Molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-XL
-
3 (Edelfosine): molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-XL. Cancer Res 57: 1320-1328
-
(1997)
Cancer Res
, vol.57
, pp. 1320-1328
-
-
Molinedo, F.1
Fernandes-Luna, J.L.2
Gajatc, C.3
Martin-Martin, B.4
Benito, A.5
Martinez-Dalmau, R.6
Modolell, M.7
-
27
-
-
0023654425
-
Evidence of protein kinase C involvement in phorbol diester-stimulated arachidonic acid release and prostaglandin synthesis
-
Parker J, Daniel LW, Waite M (1987) Evidence of protein kinase C involvement in phorbol diester-stimulated arachidonic acid release and prostaglandin synthesis. J Biol Chem 262: 5385-5393
-
(1987)
J Biol Chem
, vol.262
, pp. 5385-5393
-
-
Parker, J.1
Daniel, L.W.2
Waite, M.3
-
28
-
-
0028069064
-
Signalling pathways as targets for anticancer drug design
-
Powis, G (1994) Signalling pathways as targets for anticancer drug design. Pharmacol Ther 62: 57-95
-
(1994)
Pharmacol Ther
, vol.62
, pp. 57-95
-
-
Powis, G.1
-
29
-
-
0028017791
-
Signalling targets for the development of cancer drugs
-
Powis G, Workman P (1994) Signalling targets for the development of cancer drugs. Anticancer Drug Des 9: 263-277
-
(1994)
Anticancer Drug des
, vol.9
, pp. 263-277
-
-
Powis, G.1
Workman, P.2
-
30
-
-
0028984592
-
Advances in ether phospholipids treatment of cancer
-
Principe P, Braquet P (1995) Advances in ether phospholipids treatment of cancer. Crit Rev Oncol 18: 155-178
-
(1995)
Crit Rev Oncol
, vol.18
, pp. 155-178
-
-
Principe, P.1
Braquet, P.2
-
31
-
-
0026516946
-
Inhibition of protein kinase C by ether-linked lipids is not correlated with their antineoplastic activity on WEH1-3B and R6X-B15 cells
-
Salari H, Dryden P, Davenport R, Howard S, Jones K, Bittman R (1992) Inhibition of protein kinase C by ether-linked lipids is not correlated with their antineoplastic activity on WEH1-3B and R6X-B15 cells. Biochim Biophys Acta 1134: 81-88.
-
(1992)
Biochim Biophys Acta
, vol.1134
, pp. 81-88
-
-
Salari, H.1
Dryden, P.2
Davenport, R.3
Howard, S.4
Jones, K.5
Bittman, R.6
-
32
-
-
0023507175
-
Cytotoxic effects of ether lipids and derivatives in human nonneoplastic hone marrow cells and leukemic cells in vitro
-
Schick HD, Berdel WE, Fromm M, Fink U, Jehn U, Ulm K, Reichert A, Eibl H, Unger C, Rastetter J (1987) Cytotoxic effects of ether lipids and derivatives in human nonneoplastic hone marrow cells and leukemic cells in vitro. Lipids 22:904-910
-
(1987)
Lipids
, vol.22
, pp. 904-910
-
-
Schick, H.D.1
Berdel, W.E.2
Fromm, M.3
Fink, U.4
Jehn, U.5
Ulm, K.6
Reichert, A.7
Eibl, H.8
Unger, C.9
Rastetter, J.10
-
34
-
-
0023511572
-
Increased membrane permeability for an untitumoral alkyl lysophospholipid in sensitive tumor cells
-
Storch J, Munder PG (1987) Increased membrane permeability for an untitumoral alkyl lysophospholipid in sensitive tumor cells. Lipids 22: 813-819
-
(1987)
Lipids
, vol.22
, pp. 813-819
-
-
Storch, J.1
Munder, P.G.2
-
35
-
-
0029980868
-
Relationship between arachidonale-phospholipid signalling and apoptosis
-
Surette ME, Winklerv JD, Fonteh AN, Chilton FH (1996) Relationship between arachidonale-phospholipid signalling and apoptosis. Biochemistry 35: 9187-9196
-
(1996)
Biochemistry
, vol.35
, pp. 9187-9196
-
-
Surette, M.E.1
Winklerv, J.D.2
Fonteh, A.N.3
Chilton, F.H.4
-
36
-
-
0019425068
-
The effects of alkyllysophospholipids on leukemic cell lines. I. Differential action on two human leukemic cell lines, HL-60 and K562
-
Tidwell T, Guzman G, Vogler WR (1981) The effects of alkyllysophospholipids on leukemic cell lines. I. Differential action on two human leukemic cell lines, HL-60 and K562. Blood 57: 794-797
-
(1981)
Blood
, vol.57
, pp. 794-797
-
-
Tidwell, T.1
Guzman, G.2
Vogler, W.R.3
-
37
-
-
0026941672
-
Protein kinase C beta gene expression is associated with susceptibility of human promyelocytic leukemia cells to phorbol ester-induced differentiation
-
Tonetti DA, Horio M, Collart FR, Huberman E (1992) Protein kinase C beta gene expression is associated with susceptibility of human promyelocytic leukemia cells to phorbol ester-induced differentiation. Cell Growth Differ 3: 739-745
-
(1992)
Cell Growth Differ
, vol.3
, pp. 739-745
-
-
Tonetti, D.A.1
Horio, M.2
Collart, F.R.3
Huberman, E.4
-
38
-
-
0028168429
-
Protein kinase C-beta is required for macrophage differentiation of human HL-60 leukemia cells
-
Tonetti DA, Henning-Chubb C, Yamanishi DT, Huberman E (1994) Protein kinase C-beta is required for macrophage differentiation of human HL-60 leukemia cells. J Biol Chem 269: 23230-23235
-
(1994)
J Biol Chem
, vol.269
, pp. 23230-23235
-
-
Tonetti, D.A.1
Henning-Chubb, C.2
Yamanishi, D.T.3
Huberman, E.4
-
39
-
-
0024238610
-
Hexadecylphosphocholine (D18506) in the topical treatment of skin metastases: A phase-1 trial
-
Unger C, Eibl H, Breiser A, Heyden HW von, Engel J, Hilgard P, Sindermann H, Peukert M, Nagel GA (1988) Hexadecylphosphocholine (D18506) in the topical treatment of skin metastases: a phase-1 trial. Onkologie 11: 295-296
-
(1988)
Onkologie
, vol.11
, pp. 295-296
-
-
Unger, C.1
Eibl, H.2
Breiser, A.3
Von Heyden, H.W.4
Engel, J.5
Hilgard, P.6
Sindermann, H.7
Peukert, M.8
Nagel, G.A.9
-
40
-
-
0031018831
-
Ether lipids are effective cytotoxic drugs against multidrug-rcsistant acute leukemia cells and can act by the induction of apoptosis
-
Verdonck LF, Heugten HG (1997) Ether lipids are effective cytotoxic drugs against multidrug-rcsistant acute leukemia cells and can act by the induction of apoptosis. Leuk Res 21: 37-43
-
(1997)
Leuk Res
, vol.21
, pp. 37-43
-
-
Verdonck, L.F.1
Heugten, H.G.2
-
41
-
-
0023503111
-
Experimental studies on the role of alkyl lysophospholipids in autologous bone marrow transplantation
-
Vogler WR, Olson AC, Okamoto S, Somberg LB, Glasser L (1987) Experimental studies on the role of alkyl lysophospholipids in autologous bone marrow transplantation. Lipids 22: 919-924
-
(1987)
Lipids
, vol.22
, pp. 919-924
-
-
Vogler, W.R.1
Olson, A.C.2
Okamoto, S.3
Somberg, L.B.4
Glasser, L.5
-
42
-
-
0030612643
-
Protein kinase C β11 activation by 1-β-D-arabinofuranosylcytosine is antagonistic to stimulation of apoptosis and Bcl-2α down-regulation
-
Whitman SP, Civoli F, Daniel LW (1997) Protein kinase C β11 activation by 1-β-D-arabinofuranosylcytosine is antagonistic to stimulation of apoptosis and Bcl-2α down-regulation. J Biol Chem 272: 23481-23484
-
(1997)
J Biol Chem
, vol.272
, pp. 23481-23484
-
-
Whitman, S.P.1
Civoli, F.2
Daniel, L.W.3
-
43
-
-
0030426905
-
Inhibitors of coenzyme A-independent transacylase induce apoptosis in human HL-60 cells
-
Winkler JD, Eris T, Sung CM, Chabot-Fletcher M, Mayer RJ, Surette ME, Chilton FH (1996) Inhibitors of coenzyme A-independent transacylase induce apoptosis in human HL-60 cells. J Pharmacol Exp Ther 279: 956-966
-
(1996)
J Pharmacol Exp Ther
, vol.279
, pp. 956-966
-
-
Winkler, J.D.1
Eris, T.2
Sung, C.M.3
Chabot-Fletcher, M.4
Mayer, R.J.5
Surette, M.E.6
Chilton, F.H.7
-
44
-
-
0030839309
-
1-O-octadecyl-2-O-methylglycerophosphocholine inhibits protein kinase C dependent phosphorylation of endogenous proteins in MCF-7 cells
-
Zhou X, Arthur G (1997) 1-O-octadecyl-2-O-methylglycerophosphocholine inhibits protein kinase C dependent phosphorylation of endogenous proteins in MCF-7 cells. Biochem J 324: 897-902
-
(1997)
Biochem J
, vol.324
, pp. 897-902
-
-
Zhou, X.1
Arthur, G.2
|