Shifting the equilibrium mixture of gramicidin double helices toward a single conformation with multivalent cationic salts

Biophysical Journal

Volumn 75, Issue 2, 1998, Pages 635-640

  Doyle, Declan A ^a,b   Wallace, B A ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRAMICIDIN;

ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; IONIC STRENGTH; LIPID BILAYER; PROTEIN CONFORMATION; SPECTROSCOPY; STRUCTURE ANALYSIS;

EID: 0031874222     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(98)77553-8     Document Type: Article

References (13)

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4. Chen, Y., and B. A. Wallace. 1997. The effects of calcium ions on double helical forms of gramicidin. Eur. Biophys. J. 65:65-74.
5. Doyle, D. A., and B. A. Wallace. 1997. The crystal structure of a gramicidin/potassium thiocyanate complex. J. Mol. Biol. 266:963-977.
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7. 5.6) structure of gramicidin A: alternative patterns of helical association and deformation. Proc. Natl. Acad. Sci. USA. 88:5345-5349.
8. Sarges, R., and B. Witkop. 1965. Gramicidin A. V. The structure of valine- and isoleucine-gramicidin A. J. Am. Chem. Soc. 87:2011-2020.
9. Savitzky, A., and M. J. E. Golay. 1964. Smoothing and differentiation of data by simplified least squares procedures. Anal. Chem. 36:1627-1639.
10. Veatch, W. R., E. T. Fossel, and E. R. Blout. 1974. The conformation of gramicidin A. Biochemistry. 13:5249-5256.
11. Wallace, B. A. 1983. Gramicidin adopts distinctly different conformations in organic solvents and in membranes. Biopolymers. 22:397-402.
12. Wallace, B. A., and K. Ravikumar. 1988. The gramicidin pore: crystal structure of a cesium complex. Science. 241:182-187.
13. 13C-enriched gramicidin in phosphatidyl-choline vesicles. J. Mol. Biol. 143:1-19.