Tumor necrosis factor-α mediated activation of signal transduction cascades and transcription factors in 3T3-L1 adipocytes

Advances in Enzyme Regulation

Volumn 38, Issue 1, 1998, Pages 333-347

  Jain, Renu G ^a   Meredith, Michael J ^b   Pekala, Phillip H ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C-JUN AMINO-TERMINAL KINASE; CERAMIDE; DNA BINDING PROTEIN; GLUTATHIONE; PROTEIN KINASE (CALCIUM,CALMODULIN); TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ADIPOCYTE; ANIMAL; ANIMAL CELL; CELL STRAIN 3T3; CONFERENCE PAPER; DIABETES MELLITUS; ENZYME ACTIVATION; GENETICS; METABOLISM; MOUSE; NONHUMAN; OBESITY; OXIDATIVE STRESS; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

3T3 CELLS; ADIPOCYTES; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CERAMIDES; DNA-BINDING PROTEINS; GLUTATHIONE; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; PHOSPHORYLATION; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0031874033     PISSN: 00652571     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0065-2571(97)00007-1     Document Type: Conference Paper

References (49)

1. J. VILCEK and T. L. LEE, Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions, J. Biol. Chem. 266, 7313-7316 (1991).
2. K. J. TRACEY and A. CERAMI, Tumor necrosis factor, other cytokines and disease, Annu. Rev. Cell Biol. 9, 317-343 (1993).
3. W. FIERS, Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level, FEBS Lett. 285, 199-212 (1991).
4. J. M. STEPHENS and P. H. PEKALA, Transcriptional repression of the GLUT4 and C/EBP genes in 3T3-L1 adipocytes by tumor necrosis factor-α, J. Biol. Chem. 266, 21839-21845 (1991).
5. J. M. STEPHENS and P. H. PEKALA, Transcriptional repression of the C/EBP-α and GLUT4 genes in 3T3-L1 adipocytes by tumor necrosis factor-α. Regulation is coordinate and independent of protein synthesis, J. Biol. Chem. 267, 13580-13584 (1992).
6. J. M. STEPHENS, J. LEE and P. F. PILCH, Tumor necrosis factor-α-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction, J. Biol. Chem. 272, 971-976 (1997).
7. G. S. HOTAMISLIGIL, N. S. SHARGILL and B. M. SPIEGELMAN, Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance, Science 259, 87-91 (1993).
8. G. S. HOTAMISLIGIL, P. ARNER, J. F. CARO, R. L. ATKINSON and B. M. SPIEGELMAN, Increased adipose tissue expression of tumor necrosis factor-α in human obesity and insulin resistance, J. Clin. Invest. 95, 2409-2415 (1995).
9. G. S. HOTAMISLIGIL, P. PERALDI, A. BUDAVARI, R. ELLIS, M. F. WHITE and B. SPIEGELMAN, IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α- and obesity-induced insulin resistance, Science 271, 665-668 (1996).
10. C. A. SMITH, T. FARRAH and R. G. GOODWIN, The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death, Cell 76, 959-962 (1994).
11. P. VANDENABEELE, W. DECLERCQ, R. BAYAERT and W. FIERS, Two tumour necrosis factor receptors: structure and function, Trends in Cell Biol. 5, (1995) 392-399.
12. L. A. TARTAGLIA, T. M. AYRES, G. H. WONG and D. V. GOEDDEL, A novel domain within the 55 kd TNF receptor signals cell death, Cell 74, 845-853 (1993).
13. L. A. TARTAGLIA, M. ROTHE, Y. F. HU and D. V. GOEDDEL, Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor, Cell 73, 213-216 (1993).
14. G. H. WONG, L. A. TARTAGLIA, M. S. LEE and D. V. GOEDDEL, Antiviral activity of tumor necrosis factor is signaled through the 55-kDa type I TNF receptor, J. Immunol. 9, 3350-3353 (1992).
15. L. A. TARTAGLIA, D. PENNICA and D. V. GOEDDEL, Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor, J. Biol. Chem. 268, 18542-18548 (1993).
16. S. ZHANG, J. HAN, M. A. SELLS, J. CHERNOFF, U. G. KNAUS, R. J. ULEVITCH and G. M. BOKOCH, Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1, J. Biol. Chem. 270, 23934-23936 (1995).
17. P. VANDENABEELE, W. DECLERCQ, D. VERCAMMEN, D. C. VAN, J. GROOTEN, H. LOETSCHER, M. BROCKHAUS, W. LESSLAUER and W. FIERS, Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma, J. Exp. Med. 176, 1015-1024 (1992).
18. E. FEINSTEIN, A. KIMCHI, D. WALLACH, M. BOLDIN and E. VARFOLOMEEV, The death domain: a module shared by proteins with diverse cellular functions, Trends Biochem. Sci. 20, 342-344 (1995).
19. H. HSU, H. B. SHU, M. G. PAN and D. V. GOEDDEL, TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways, Cell 84, 299-308 (1996).
20. B. Z. STANGER, P. LEDER, T. LEE, E. KIM and B. SEED, RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death, Cell 81, 513-523 (1995).
21. M. P. BOLDIN, E. E. VARFOLOMEEV, Z. PANCER, I. L. METT, J. H. CAMONIS and D. WALLACH, A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain, J. Biol. Chem. 270, 7795-7798 (1995).
22. A. M. CINNAIYAN, 'ROURKEK. O, M. TEWARI and V. M. DIXIT, FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis, Cell 81, 505-512 (1995).
23. H. HSU, J. HUANG, H. B. SHU, V. BAICHWAL and D. V. GOEDDEL, TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex, Immunity 4, 387-396 (1996).
24. S. NAGATA, Apoptosis by death factor, Cell 88, 355-365 (1997).
25. A. R. SCHIEVELLA, J. H. CHEN, J. R. GRAHAM and L. LIN, MADD, A novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase, J. Biol. Chem. 272, 12069-12075 (1997).
26. S. ADAM-KLAGES, D. ADAM, K. WEIGMANN, S. STRUVE, W. KOLONUS, J. SCHNEIDER-MEWRGENER and M. KRONKE, FAN, a novel WD-repeat protein couples the p55 TNF-receptor to a neutral sphingomyelinase, Cell 86, 937-947 (1996).
27. S. MATHIAS, K. A. DRESSLER and R. N. KOLESNICK, Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor α, Proc. Natl. Acad. Sci. U.S.A. 88, 10009-10013 (1991).
28. C. K. JOSEPH, H. S. BYUN, R. BITTMAN and R. N. KOLESNICK, Substrate recognition by ceramide-activated protein kinase. Evidence that kinase activity is proline-directed, J. Biol. Chem. 268, 20002-20006 (1993).
29. B. YAO, Y. ZHANG, S. DELIKAT, S. MATHIAS, S. BASU and R. KOLESNICK, Nature 378, 307-310 (1995).
30. A. G. UREN and D. L. VAUX, TRAF proteins and meprins share a conserved domain, Trends Biochem. Sci. 21, 244-245 (1996).
31. M. ROTHE, V. SARMA, V. M. DIXIT and D. V. GOEDDEL, TRAF2-mediated activation of NF-κB by TNF receptor 2 and CD40, Science 269, 1424-1427 (1995).
32. Z. CAO, R. M. UMEK and S. L. MCKNIGHT, Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells, Genes Dev. 5, 1538-1552 (1991).
33. M. TAKEUCHI, M. ROTHE and D. V. GOEDDEL, Anatomy of TRAF2. Distinct domains for nuclear factor-κB activation and association with tumor necrosis factor signaling proteins, J. Biol. Chem. 271, 19935-19942 (1996).
34. M. ROTHE, S. C. WONG, W. J. HENZEL and D. V. GOEDDEL, A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor, Cell 78, 681-692 (1994).
35. H. B. SHU, M. TAKEUCHI and D. V. GOEDDEL, The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex, Proc. Natl. Acad. Sci. U.S.A. 93, 13973-13978 (1996).
36. K. M. MCGOWAN, S. D. LONG and P. H. PEKALA, Glucose transporter gene expression: regulation of transcription and mRNA stability, Pharmac. Ther. 66, 465-505 (1995).
37. P. PEKALA, R. JAIN, A. PRUETT, S. LONG, L. SOMMERVILLE and M. MEREDITH, A ceramide activated signal transduction pathway controls GLUT4 gene expression in 3T3-L1 adipocytes. Keystone Symposium on the Adipose Cell, Park City, UT. p. 8 (1997).
38. S. D. LONG and P. H. PEKALA, Lipid mediators of insulin resistance: ceramide signalling down-regulates GLUT4 gene transcription in 3T3-L1 adipocytes, Biochem. J. 319, 179-184 (1996).
39. M. C. FARRIS and D. J. REED, Measurement of glutathione and glutathione disulfide efflux from isolated rat hepatocytes, pp. 349-355 in Isolation, Characterization and Use of Hepatocytes, (R. A. HARRIS and N. W. CORNELL, eds.). Elsevier/North Holland Biomedical Press, Amsterdam, The Netherlands (1983).
40. A. F. S. A. HABEEB, Reaction of protein sulfhydral groups with Ellman's reagent, Merthods Enzymol. 25, 457-464 (1972).
41. J. M. KYRIAKIS, P. BANERJEE, E. NIKOLAKAKI, T. DAI, E. A. RUBIE, M. F. AHMAD, J. AVRUCH and J. R. WOODGETT, The stress-activated protein kinase subfamily of c-Jun kinases, Nature 369, 156-160 (1994).
42. J. N. IHLE, Janus kinases in cytokine signalling, Phil. Trans. R. Soc. London 351, 159-166 (1996).
43. J. E. DARNELL, I. M. KERR and G. R. STARK, Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins, Science 264, 1415-1421 (1994).
44. C. SCHINDLER and J. E. DARNELL, Transcriptional responses to polypeptide ligands: the JAK-STAT pathway, Annu. Rev. Biochem. 64, 621-651 (1995).
45. J. M. STEPHENS, R. F. MORRISON and P. F. PILCH, The expression and regulation of STATs during 3T3-L1 adipocyte differentiation, J. Biol. Chem. 271, 10441-10444 (1996).
46. N. ISRAEL, M. A. GOUGEROT-POCIDALO, F. AILLET and J. L. VIRELIZIER, Redox status of cells influences constitutive or induced NF-κB translocation and HIV long terminal repeat activity in human T and monocytic cell lines, J. Immunol. 149, 3386-3397 (1992).
47. E. BEUTLER, Nutritional and metabolic aspects of glutathione, Ann. Rev. Nutr. 9, 287-305 (1989).
48. M. L. FREEMAN and M. J. MEREDITH, Modulation of diamide toxicity in thermotolerant cells by inhibition of protein synthesis, Cancer Res. 49, 4493-4498 (1989).
49. M. VERHEIJ, R. BOSE, X. H. LIN, B. YAO, W. D. JARVIS, S. GRANT, M. J. BIRRER, E. SZABO, L. I. ZON, J. M. KYRIAKIS, A. HAIMOVITZ-FRIEDMAN, Z. FUKS and R. N. KOLESNICK, Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis, Nature 380, 75-79 (1996).