Tumor necrosis factor-alpha production enhancing activity of substituted 3'-methylthalidomide: Influence of substituents at the phthaloyl moiety on the activity and stereoselectivity

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 7, 1998, Pages 1165-1168

  Miyachi, Hiroyuki ^a   Koiso, Yukiko ^a   Shirai, Ryuichi ^a   Niwayama, Satomi ^b   Liu, Jun O ^b   Hashimoto, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

12 O tetradecanoyl phorbol 13 acetate; 3' methylthalidomide; Human leukemia cell line; Tumor necrosis factor

Indexed keywords

3' METHYLTHALIDOMIDE; 5 AMINO 3' METHYLTHALIDOMIDE; CYTOKINE; PHORBOL 13 ACETATE 12 MYRISTATE; THALIDOMIDE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL SPECIFICITY; CELL TYPE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IMMUNOREGULATION; LEUKEMIA CELL; STEREOCHEMISTRY;

EID: 0031873804     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.1165     Document Type: Article

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