Synthesis of a new homologous series of p-chlorophenyl alcohol amides, their anticonvulsant activity and their testing as potential GABA(B) receptor antagonists

Arzneimittel-Forschung/Drug Research

Volumn 48, Issue 8, 1998, Pages 797-801

  Meza Toledo, Sergio E ^a   Juárez Carvajal, Enedina ^a   Carvajal Sandoval, Guillermo ^a  

^a INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

Anticonvulsants; Antiepileptics; Chlorophenyl alcohol amides; GABA(B) receptor antagonists; Neuropharmacology; Synthesis

Indexed keywords

2 HYDROXY 2 (4' CHLOROPHENYL)BUTYRAMIDE; 3 HYDROXY 3 (4' CHLOROPHENYL)PENTANAMIDE; 3 HYDROXY 3 PHENYLPENTANAMIDE; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; 4 HYDROXY 4 (4' CHLOROPHENYL)HEXANAMIDE; ANTICONVULSIVE AGENT; BACLOFEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SEIZURE; STRUCTURE ACTIVITY RELATION;

AMIDES; ANIMALS; ANTICONVULSANTS; BACLOFEN; CONVULSANTS; INJECTIONS, INTRAPERITONEAL; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; PENTYLENETETRAZOLE; RECEPTORS, GABA-B; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031873255     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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