Acid-catalysed hydrolysis and benzodiazepine-like properties of 5-(dialkylamino)- and 5-(alkylthio)-substituted 8-chloro-6-phenyl-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepines in mice

Journal of Pharmacy and Pharmacology

Volumn 50, Issue 7, 1998, Pages 723-728

  Caccia, Silvio ^a   Grossi, Giancarlo ^b   Fracasso, Claudia ^a   Nacca, Angelo ^a   Cagnotto, Alfredo ^a   Mennini, Tiziana ^a   Ghia, Marco ^b   Roma, Giorgio ^b  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; BENZODIAZEPINE RECEPTOR; RL 218; RL 236; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG STABILITY; DRUG STRUCTURE; DRUG TRANSFORMATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PH; RECEPTOR AFFINITY; STOMACH JUICE;

EID: 0031872371     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1998.tb07132.x     Document Type: Article

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