Cloning and expression analyses of AtMRP4 a novel MRP-like gene from Arabidopsis thaliana

Molecular and General Genetics

Volumn 258, Issue 6, 1998, Pages 655-662

  Sanchez Fernandez R ^a   Ardiles Diaz W ^a   Van Montagu, M ^a   Inze D ^b   May, M J ^a,c  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c Bayer Cropscience Belgium   (Belgium)

Author keywords

Arabidopsis thaliana; Glutathione conjugate pump; Stress; Xenobiotic detoxification

Indexed keywords

CARRIER PROTEIN; GLUTATHIONE; HERBICIDE; XENOBIOTIC AGENT;

AMINO ACID SEQUENCE; ARABIDOPSIS; ARTICLE; CONTROLLED STUDY; CYTOSOL; DETOXIFICATION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE STRUCTURE; GLUTATHIONE METABOLISM; MOLECULAR CLONING; MULTIGENE FAMILY; NONHUMAN; PHYLOGENY; PHYTOCHEMISTRY; PLANT CELL; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STRESS;

AMINO ACID SEQUENCE; ANTIDOTES; ARABIDOPSIS; CADMIUM; CARRIER PROTEINS; CLONING, MOLECULAR; GENE EXPRESSION REGULATION, PLANT; GENES, PLANT; GLUTATHIONE; HERBICIDES; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; OXIDATIVE STRESS; PHYLOGENY; RNA, MESSENGER; RNA, PLANT; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID;

ARABIDOPSIS; ARABIDOPSIS THALIANA; EMBRYOPHYTA; EUKARYOTA;

EID: 0031872369     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380050779     Document Type: Article

References (39)

1. Alscher RG (1989) Biosynthesis and antioxidant functions of glutathione in plants. Physiol Plant 77:457-464
2. Bakos E, Hegedüs T, Holló Z, Welker E, Tusnády GE, Zaman GJR, Flens MJ, Váradi A, Sarkadi B (1996) Membrane topology and glycosylation of the human multidrug resistance-associated protein. J Biol Chem 271:12322-12326
3. Cole SPC, Bhardwaj G, Gerlach JH, Mackie JE, Grant CE, Almquist KC, Stewart AJ, Kurz EU, Duncan AMV, Deeley RG (1992) Overexpression of a transporter gene in a multi-drug-resistant human lung cancer cell line. Science 258:1650-1654
4. Di Laurenzio L, Wysocka-Diller J, Malamy JE, Pysh L, Helariutta Y, Freshour G, Hahn MG, Feldmann KA, Benfey PN (1996) The SCARECROW gene regulates an asymmetric cell division that is essential for generating the radial organization of the Arabidopsis root. Cell 86:423-433
5. Gaillard C, Dufaud A, Tommasini R, Kreuz K, Amrhein N, Martinoia E (1994) A herbicide antidote (safener) induces the activity of both the herbicide detoxifying enzyme and of a vacuolar transporter for the detoxified herbicide. FEBS Lett 352:219-221
6. Glab N, Labidi B, Qin L-X, Trehin C, Bergounioux C, Meijer L (1994) Olomoucine, an inhibitor of the cdc2 cdk2 kinases activity, blocks plant cells at the G1 to S and G2 to M cell cycle transitions. FEBS Lett 353:207-211
7. Hebsgaard SM, Korning PG, Tolstrup N, Engelbrecht J, Rouzé P (1996) Splice site prediction in Arabidopsis thaliana pre-mRNA combining local and global sequence information. Nucleic Acids Res 24:3439-3452
8. Heim DR, Larrinua IM (1989) Primary site of action of amitrole in Arabidopsis thaliana involves inhibition of root elongation but not of histidine or pigment biosynthesis. Plant Physiol 91:1226-1231
9. Higgins CF (1992) ABC transporters: from microorganisms to man. Ann Rev Cell Biol 8:67-113
10. Hipfner DR, Almquist KC, Leslie HM, Gerlach JH, Grant CE, Deeley RG, Cole SP (1997) Membrane topology of the multidrug resistance protein (MRP). J Biol Chem 272:23623-23630
11. Irzyk GP, Fuerst EP (1993) Purification and characterisation of a glutathione S-transferase from benoxacor-treated maize (Zea mays). Plant Physiol 102:803-810
12. Ishikawa T, Estebauer H, Sies H (1986) Role of cardiac glutathione transferase and of the glutathione S-conjugate export system in biotransformation of 4-hydroxynonenal in the heart. J Biol Chem 261:1576-1581
13. Ishikawa T, Wright CD, Ishizuka H (1994) GS-X pump is functionally overexpressed in cis-diamminedichloroplatinum (II)-resistant human leukemia HL-60 cells and down-regulated by cell differentiation. J Biol Chem 269:29085-29093
14. Ishikawa T, Bao JJ, Yamane Y, Akimaru K, Frindrich K, Wright CD, Kuo MT (1996) Coordinated induction of MRP/GS-X pump and γ-glutamylcysteine synthetase by heavy metals in human leukemia cells. J Biol Chem 271:14981-14988
15. Kondo T, Yoshida K, Urata Y, Goto S, Gasa S, Taniguchi N (1993) γ-glutamylcysteine synthetase and active transport of gluthatione S-conjugates arc responsive to heat shock in K562 erythroid cells. J Biol Chem 268:20366-20372
16. Kool M, Dehaas M, Scheffer GL, Scheper RJ, Vaneijk NJT, Juijn JA, Baas F, Borst P (1997) Analysis of expression of cMOAT (MRP2), MRP3, and MRP5, homologues of the human multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res 57:3537-3547
17. Lenehan PF, Gutiérrez PL, Wagner JL, Milak N, Fisher GR, Ross DD (1995) Resistance to oxidants associated with elevated catalase activity in HL-60 leukemia cells that overexpress multidrug-resistance protein does not contribute to the resistance to daunorubicin manifested by these cells. Cancer Chemother Pharmacol 35:377-386
18. Li Z-S, Zhao Y, Rea PA (1995) Magnesium adenosine 5′-triphosphate-energized transport of glutathione S-conjugates by plant vacuolar membrane vesicles. Plant Physiol 107:1257-1268
19. Li Z-S, Szczypka MS, Lu Y-P, Thiele DJ, Rea PA (1996) The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. J Biol Chem 271:6509-6517
20. Li Z-S, Drozdowicz Y, Lu Y-P, Alfenito M, Walbot V, Rea PA (1997) Substrate range, kinetics and energetics of vacuolar glutathione-conjugate transport. Plant Physiol 114 (supplement):198
21. 4 and chemotherapeutic agents in membrane vesicles. J Biol Chem 271:9675-9682
22. Loe DW, Almquist CK, Cole SPC, Deeley RG (1996b) ATP-dependent 17β-estradiol 17-(β-D-glucuronide) transport by multidrug resistance protein (MRP). J Biol Chem 271:9683-9689
23. Lu Y-P, Li Z-S, Rea PA (1997) AtMRP1 gene of Arabidopsis encodes a glutathione S-conjugate pump: isolation and functional definition of a plant ATP-binding cassette transporter gene. Proc Natl Acad Sci USA 94:8243-8247
24. Lu Y-P, Li Z-S, Drozdowicz Y, Hortensteiner S, Martinoia E, Rea PA (1998) AtMRP2, an Arabidopsis ATP-binding cassette transporter able to transport glutathione S-conjugates and chlorophyll catabolites. Plant Cell 10:267-282
25. Marrs KA, Alfenito MA, Lloyd AM, Walbot V (1995) A glutathione S-transterase involved in vacuolar transfer encoded by the maize gene Bronze-2. Nature 375:397-400
26. Martinoia E, Grill E, Tommasini R, Kreuz K, Amrhein N (1993) ATP-dependent glutathione S-conjugate 'export' pump in the vacuolar membrane of plants. Nature 364:247-249
27. May MJ, Leaver C (1992) Oxidative stimulation of glutathione synthesis in Arabidopsis thaliana suspension cultures. Plant Physiol 103:621-627
28. Mayer R, Kartenbeck J, Buchler M, Jedlitschky G, Leier I (1995) Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes. J Cell Biol 131:137-150
29. Minet M, Dufour ME, Lacroute F (1992) Complementation of Saccharomyces cerevisiae auxotrophic mutants by Arabidopsis thaliana cDNAs. Plant J 2:417-422
30. Moffat GJ, McLaren AW, Wolf CR (1996) Sp1-mediated transcriptional activation of the human Pi class glutathione S-transferase promoter. J Biol Chem 271:1054-1060
31. Moradas-Ferreira P, Costa V, Piper P, Mager W (1996) The molecular defences against reactive oxygen species in yeast. Mol Microbiol 19:651-658
32. Ouellette M, Fase-Fowler F, Borst P (1990) The amplified H circle of methotrexate-resistant Leishmania tarentolae contains a novel P-glycoprotein gene. EMBO J 9:1027-1033
33. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual (2nd edn). Cold Spring Harbor Laboratory Press, New York
34. Schena M, Davis RW (1992) HD-Zip proteins: members of an Arabidopsis homeodomain protein superfamily. Proc Natl Acad Sci USA 89:3894-3898
35. Szczypka MS, Wemmie JA, Moye-Rowley WS, Thiele DJ (1994) A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CETR) and multidrug resistance-associated protein. J Biol Chem 269:22853-22857
36. Tommasini R, Evers R, Vogt E, Mornett C, Zaman GJR, Schinkel H, Borst P, Martinoia E (1996) The human multidrug resistance-associated protein functionally complements the yeast cadmium resistance factor 1. Proc Natl Acad Sci USA 93:6743-6748
37. Tommasini R, Vogt E, Schmid J, Fromentau M, Amrhein N, Martinoia E (1997) Differential expression of genes encoding for ABC transporters alter treatment of Arabidopsis with xenobiotics. FEBS Lett 411:206-210
38. Wiegand RC, Shah DM, Mozer TJ, Harding EI, Díaz-Collier J, Saunders C, Jaworski EG, Tiemeier DC (1986) Messenger RNA encoding a glutathione-S-transferase responsible for herbicide tolerance in maize is induced in response to safener treatment. Plant Mol Biol 7:235-243
39. Zhu Q, Center MS (1996) Evidence that SP1 modulates transcriptional activity of the multidrug resistance-associated protein gene. DNA Cell Biol 15:105-111