A discussion of how terlipressin limits mortality in cases of bleeding oesophageal varices

European Journal of Gastroenterology and Hepatology

Volumn 10, Issue 7, 1998, Pages 549-552

  Lebrec, Didier ^a  

^a BEAUJON HOSPITAL   (France)

Author keywords

Bleeding oesophageal varices; Portal hypertension; Terlipressin

Indexed keywords

TERLIPRESSIN; VASOACTIVE AGENT;

ARTICLE; ENDOSCOPIC SCLEROTHERAPY; ESOPHAGUS VARICES BLEEDING; HEMODYNAMICS; HEMOSTASIS; HUMAN; KIDNEY FUNCTION; LIVER BLOOD FLOW; MORTALITY; PORTAL HYPERTENSION; PRIORITY JOURNAL; STOMACH BLOOD FLOW;

EID: 0031872364     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-199807000-00004     Document Type: Article

References (31)

1. Grace ND. Portal hypertension and variceal bleeding. Curr Opin Gastroenterol 1993; 9:441-449.
2. Sherlock S, Dooley J. Diseases of the liver and biliary system. Oxford: Blackwell Scientific; 1993.
3. Feu F, Ruiz del Arbol L, Bañares R, Planas R, Bosch J, Members of the Variceal Bleeding Study Group. Double-blind randomized controlled trial comparing terlipressin and somatostatin for acute variceal hemorrhage. Gastroenterology 1996; 111:1291-1299.
4. Walker S, Stiehl A, Raedsch R, Kommerell B. Terlipressin in bleeding esophageal varices. A placebo controlled double-blind study. Hepatology 1986; 6:112-115.
5. D'Amico G, Traina M, Vizzini G, Tiné F, Politi F, Montalbano L, et al. Terlipressin or vasopressin plus transdermal nitroglycerin in a treatment strategy for digestive bleeding in cirrhosis: a randomized clinical trial. J Hepatol 1994; 20:206-212.
6. Silvain C, Carpentier S, Sautereau D, Czernichow B, Metreau JM, Fort E, et at. Terlipressin plus transdermal nitroglycerin vs. octreotide in the control of acute bleeding from esophageal varices: a multicenter randomized trial. Hepatology 1993; 18:61-65.
7. Levacher S, Letoumelin P, Pateron D, Blaise M, Lapanndry C, Pourriat J-L. Early administration of terlipressin plus glyceryl trinitrate to control active upper gastrointestinal bleeding in cirrhotic patients. Lancet 1995; 346:865-868.
8. Bosch J, D'Amico G, Luca A, Garcia-Pagán JC, Feu F, Escorsell A. Drug therapy for variceal haemorrhage. In Bosch J, Groszmann RJ, editors. Portal hypertension, pathophysiology and treatment. Oxford: Blackwell Scientific; 1994. pp. 108-123.
9. Burroughs AK, Bosch J. Clinical manifestations and management of bleeding episodes in cirrhotics. In McIntyre N, Benhamou JP, Bircher J, Rizetto M, Rodés J (editors). Oxford textbook of clinical hepatology. Oxford: Oxford University Press; 1991. pp. 408-425
10. Feu F, D'Amico G, Bosch J. The acute bleeding episode: advances in drug therapy. In Arroyo V, Bosch J, Rodés J, editors. Treatments in hepatology. Barcelona: Masson; 1995. pp. 9-22.
11. Lebrec D. Hemodynamic effects of terlipressin (Glypressin) in patients with cirrhosis. In Lebrec D, Blei AT, editors. Vasopressin analogs and portal hypertension. Paris: John Libbey Eurotext; 1987. pp. 105-112.
12. Rector WG. Drug therapy for portal hypertension. Ann Intern Med 1986; 105:96-107.
13. Burroughs AK. Somatostatin and octreotide for variceal bleeding. J Hepatol 1991; 13:1-4.
14. Escorsell A, Feu F, García-Pagán JC, Luca A, Vandi JC, Casado M, et al. Hemodynamic effects of octreotide in cirrhotic patients with portal hypertension. A double-blind study. J Hepatol 1995; 23 (suppl 1):85.
15. Panés J, Piqué JM, Bordas JM, Llach J, Bosch J, Terés J, et al. Reduction of gastric hyperemia by glypressin and vasopressin administration in cirrhotic patients with portal hypertensive gastropathy. Hepatology 1994; 19:55-60.
16. Panés J, Piqué JM, Bordas JM, Casadevall M, Terés J, Bosch J, et al. Effect of bolus injection and continuous infusion of somatostatin on gastric perfusion in cirrhotic patients with portal-hypertensive gastropathy. Hepatology 1994; 20:336-341.
17. Garcia-Tsao G, Groszmann PJ, Fisher RL, Conn HO, Atterbury CE, Glickmann M. Portal pressure, presence of gastroesophageal varices and vanceal bleeding. Hepatology 1985; 5:419-429.
18. Blei AT, Groszmann RJ, Gusberg R, Conn HO. Comparison of vasopressin and triglycyl-lysine vasopressin on splanchnic and systemic hemodynamics in dogs. Dig Dis Sci 1980; 25:688-694.
19. Freeman JG, Barton JR, Record CO. Haemodynamic responses to glypressin. Gut 1985; 26:A562.
20. Rabol A, Juhl E, Schmidt A, Winkler K. The effect of vasopressin and triglycyl lysine vasopressin (Glypressin) on the splanchnic circulation in cirrhotic patients with portal hypertension. Digestion 1976; 14:285-289.
21. Freeman JG, Barton JR, Record CO. Haemodynamic responses to 1.25 and 2 mg of terlipressin intravenously in man. Aliment Pharmacol Ther 1988; 2:361-367.
22. Lebrec D, Moreau R, Cailmail S, Sogni P, Oberti F, Hadengue A. Effects of terlipressin on hemodynamics and oxygen content in conscious portal vein stenosed and cirrhotic rats receiving propranolol. J Hepatol 1993; 17:102-107.
23. Hansen EF, Becker U, Strandberg L, Hojgardt L, Madsen J, Henriksen JH, et al. Effects of intravenous glypressin on hepatic haemodynamics in anaesthetized pigs. J Hepatol 1994; 26 (suppl 1):98.
24. Moreau R, Lee SS, Hadengue A, Ozier Y, Sicot C, Lebrec D. Relationship between oxygen transport and oxygen uptake in patients with cirrhosis: effects of vasoactive drugs. Hepatology 1989; 9:427-432.
25. Vachiery F, Moreau R, Gadano A, Yang S, Sogni P, Hadengue A, et al. Hemodynamic and metabolic effects of terlipressin in patients with cirrhosis receiving a nonselective β-blocker. Dig Dis Sci 1996; 41:1722-1726.
26. Calès P, Desmorat H, Vinel JP, Caucanas JP, Ravaud A, Gerin P, et al. Incidence of large esophageal varices in patients with cirrhosis: application to prophylaxis of first bleeding. Gut 1990; 31:1298-1302.
27. North Italian Endoscopic Club for the Study and Treatment of Esophageal Varices. Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. N Engl J Med 1988; 319:983-989.
28. Lenz K, Hörtnagl H, Druml W, Reither H, Schmid D, Schneeweiss B, et al. Ornipressin in the treatment of functional renal failure in decompensated liver cirrhosis. Gastroenterology 1991; 101:1060-1067.
29. Ganne-Carrié N, Hadengue A, Mathurin P, Durand F, Erlinger S, Benhamou J-P. Hepatorenal syndrome: long-term treatment with terlipressin as a bridge to liver transplantation. Dig Dis Sci 1996; 41:1054-1056.
30. Ginès A, Salmerón JM, Ginès P, Jiménez J, Salo J, Piera C, et al. Effects of somatostatin on renal function in cirrhosis. Gastroenterology 1992; 103:1868-1874.
31. + retention in portal hypertensive rats. Gastroenterology 1993; 104:575-579.