메뉴 건너뛰기




Volumn 18, Issue 8, 1998, Pages 597-607

An IgG3-IL-2 fusion protein recognizing a murine B cell lymphoma exhibits effective tumor imaging and antitumor activity

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; IMMUNOGLOBULIN G3; INTERLEUKIN 2;

EID: 0031870775     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1998.18.597     Document Type: Article
Times cited : (20)

References (74)
  • 1
    • 0018971129 scopus 로고
    • In vitro growth of murine T cells. V. The isolation and growth of lymphoid cells infiltrating syngeneic solid tumors
    • YRON, I., WOOD, T., JR., SPIESS, P.J., and ROSENBERG, S.A. (1980). In vitro growth of murine T cells. V. The isolation and growth of lymphoid cells infiltrating syngeneic solid tumors. J. Immunol. 125, 238-245.
    • (1980) J. Immunol. , vol.125 , pp. 238-245
    • Yron, I.1    Wood Jr., T.2    Spiess, P.J.3    Rosenberg, S.A.4
  • 2
    • 0019835981 scopus 로고
    • Lysis of fresh and cultured autologous tumor by human lymphocytes cultured in T-cell growth factor
    • LOTZE, M.T., GRIMM, E.A., MAZUMDER, A., STRAUSSER, J.L., and ROSENBERG, S.A. (1981). Lysis of fresh and cultured autologous tumor by human lymphocytes cultured in T-cell growth factor. Cancer Res. 41, 4420-4425.
    • (1981) Cancer Res. , vol.41 , pp. 4420-4425
    • Lotze, M.T.1    Grimm, E.A.2    Mazumder, A.3    Strausser, J.L.4    Rosenberg, S.A.5
  • 3
    • 0019951384 scopus 로고
    • Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes
    • GRIMM, E.A., MAZUMDER, A., ZHANG, H.Z., and ROSENBERG, S.A. (1982). Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes. J. Exp. Med. 155, 1823-1841.
    • (1982) J. Exp. Med. , vol.155 , pp. 1823-1841
    • Grimm, E.A.1    Mazumder, A.2    Zhang, H.Z.3    Rosenberg, S.A.4
  • 4
    • 0025091247 scopus 로고
    • Augmentation of antibody dependent cell mediated cytotoxicity following in vivo therapy with recombinant interleukin 2
    • HANK, J.A., ROBINSON, R.R., SURFUS, J., MUELLER, B.M., REISFELD, R.A., CHEUNG, N.K., and SONDEL, P.M. (1990). Augmentation of antibody dependent cell mediated cytotoxicity following in vivo therapy with recombinant interleukin 2. Cancer Res. 50, 5234-5239.
    • (1990) Cancer Res. , vol.50 , pp. 5234-5239
    • Hank, J.A.1    Robinson, R.R.2    Surfus, J.3    Mueller, B.M.4    Reisfeld, R.A.5    Cheung, N.K.6    Sondel, P.M.7
  • 5
    • 0023605471 scopus 로고
    • Systematic preclinical study on the therapeutic properties of recombinant human interleukin 2 for the treatment of metastatic disease
    • TALMADGE, J.E., PHILLIPS, H., SCHINDLER, J., TRIBBLE, H., and PENNINGTON, R. (1987). Systematic preclinical study on the therapeutic properties of recombinant human interleukin 2 for the treatment of metastatic disease. Cancer Res. 47, 5725-5732.
    • (1987) Cancer Res. , vol.47 , pp. 5725-5732
    • Talmadge, J.E.1    Phillips, H.2    Schindler, J.3    Tribble, H.4    Pennington, R.5
  • 6
    • 0027407531 scopus 로고
    • Interleukin-2 in cancer treatment: Disappointing or (still) promising? A review
    • MAAS, R.A., DULLENS, H.F., and DEN OTTER, W. (1993). Interleukin-2 in cancer treatment: disappointing or (still) promising? A review. Cancer Immunol. Immunother. 36, 141-148.
    • (1993) Cancer Immunol. Immunother. , vol.36 , pp. 141-148
    • Maas, R.A.1    Dullens, H.F.2    Den Otter, W.3
  • 7
    • 0024827393 scopus 로고
    • Immunohistochemical correlates of response to recombinant interleukin-2-based immunotherapy in humans
    • RUBIN, J.T., ELWOOD, L.J., ROSENBERG, S.A., and LOTZE, M.T. (1989). Immunohistochemical correlates of response to recombinant interleukin-2-based immunotherapy in humans. Cancer Res. 49, 7086-7092.
    • (1989) Cancer Res. , vol.49 , pp. 7086-7092
    • Rubin, J.T.1    Elwood, L.J.2    Rosenberg, S.A.3    Lotze, M.T.4
  • 8
    • 0027522021 scopus 로고
    • Interteukin-2. A review of its pharmacological properties and therapeutic use in patients with cancer
    • WHITTINGTON, R., and FAULDS, D. (1993). Interteukin-2. A review of its pharmacological properties and therapeutic use in patients with cancer. Drugs 46, 446-514.
    • (1993) Drugs , vol.46 , pp. 446-514
    • Whittington, R.1    Faulds, D.2
  • 10
    • 0022387502 scopus 로고
    • In vivo administration of purified human interleukin 2. II. Half-life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2
    • LOTZE, M.T., MATORY, Y.L., ETTINGHAUSEN, S.E., RAYNER, A.A., SHARROW, S.O., SEIPP, C.A., CUSTER, M.C., and ROSENBERG, S.A. (1985). In vivo administration of purified human interleukin 2. II. Half-life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2. J. Immunol. 135, 2865-2875.
    • (1985) J. Immunol. , vol.135 , pp. 2865-2875
    • Lotze, M.T.1    Matory, Y.L.2    Ettinghausen, S.E.3    Rayner, A.A.4    Sharrow, S.O.5    Seipp, C.A.6    Custer, M.C.7    Rosenberg, S.A.8
  • 11
    • 0026065329 scopus 로고
    • Interleukin-2 toxicity
    • SIEGEL, J.P., and PURI, R.K. (1991). Interleukin-2 toxicity, J. Clin. Oncol. 9, 694-704.
    • (1991) J. Clin. Oncol. , vol.9 , pp. 694-704
    • Siegel, J.P.1    Puri, R.K.2
  • 12
    • 0027344034 scopus 로고
    • Pathogenesis of toxicity with human-derived interleukin-2 in experimental animals
    • HARADA, Y., and YAHARA, I. (1993). Pathogenesis of toxicity with human-derived interleukin-2 in experimental animals. Int. Rev. Exp. Pathol. 34,(Pt. A), 37-55.
    • (1993) Int. Rev. Exp. Pathol. , vol.34 , Issue.PT. A , pp. 37-55
    • Harada, Y.1    Yahara, I.2
  • 14
    • 0020586786 scopus 로고
    • The fate of interleukin-2 after in vivo administration
    • DONOHUE, J.H., and ROSENBERG, S.A. (1983). The fate of interleukin-2 after in vivo administration. J. Immunol. 130, 2203-2208.
    • (1983) J. Immunol. , vol.130 , pp. 2203-2208
    • Donohue, J.H.1    Rosenberg, S.A.2
  • 15
    • 0021217020 scopus 로고
    • Tumour regression after intralesional injection of interleukin 2 (IL-2) in bladder cancer. Preliminary report
    • PIZZA, G., SEVERINI, G., MENNITI, D., DE VINCI, C., and CORRADO, F. (1984). Tumour regression after intralesional injection of interleukin 2 (IL-2) in bladder cancer. Preliminary report. Int. J. Cancer 34, 359-367.
    • (1984) Int. J. Cancer , vol.34 , pp. 359-367
    • Pizza, G.1    Severini, G.2    Menniti, D.3    De Vinci, C.4    Corrado, F.5
  • 16
    • 0023073438 scopus 로고
    • Local administration of interleukin-2 activates lymphocytes from tumor bearing mice to recruit host immunoreactivity and inhibit tumor growth
    • FORNI, G., MUSSO, T., SANTONI, A., and GIOVARELLI, M. (1987). Local administration of interleukin-2 activates lymphocytes from tumor bearing mice to recruit host immunoreactivity and inhibit tumor growth. Prog. Clin. Biol. Res. 244, 105-114.
    • (1987) Prog. Clin. Biol. Res. , vol.244 , pp. 105-114
    • Forni, G.1    Musso, T.2    Santoni, A.3    Giovarelli, M.4
  • 17
    • 0024206262 scopus 로고
    • Treatment of recurrent squamous cell carcinoma of the head and neck with low doses of interleukin-2 injected perilymphatically
    • CORTESINA, G., DE STEFANI, A., GIOVARELLI, M., BARIOGLIO, M.G., CAVALLO, G.P., JEMMA, C., and FORNI, G. (1988). Treatment of recurrent squamous cell carcinoma of the head and neck with low doses of interleukin-2 injected perilymphatically. Cancer 62, 2482-2485.
    • (1988) Cancer , vol.62 , pp. 2482-2485
    • Cortesina, G.1    De Stefani, A.2    Giovarelli, M.3    Barioglio, M.G.4    Cavallo, G.P.5    Jemma, C.6    Forni, G.7
  • 19
    • 0024832082 scopus 로고
    • Immunotherapy of mice with a large burden of disseminated lymphoma with low-dose interleukin 2
    • MAAS, R.A., DULLENS, H.F., DE JONG, W.H., and DEN OTTER, W. (1989). Immunotherapy of mice with a large burden of disseminated lymphoma with low-dose interleukin 2. Cancer Res. 49, 7037-7040.
    • (1989) Cancer Res. , vol.49 , pp. 7037-7040
    • Maas, R.A.1    Dullens, H.F.2    De Jong, W.H.3    Den Otter, W.4
  • 23
    • 0028917158 scopus 로고
    • Elicitation of a systemic and protective anti-melanoma immune response by an IL-2 based vaccine. Assessment of critical cellular and molecular parameters
    • ZATLOUKAL, K., SCHNEEBERGER, A., BERGER, M., SCHMIDT, W., KOSZIK, F., KUTIL, R., COTTEN, M., WAGNER, E., BUSCHLE, M., MAASS, G., et al. (1995). Elicitation of a systemic and protective anti-melanoma immune response by an IL-2 based vaccine. Assessment of critical cellular and molecular parameters. J. Immunol. 154, 3406-3419.
    • (1995) J. Immunol. , vol.154 , pp. 3406-3419
    • Zatloukal, K.1    Schneeberger, A.2    Berger, M.3    Schmidt, W.4    Koszik, F.5    Kutil, R.6    Cotten, M.7    Wagner, E.8    Buschle, M.9    Maass, G.10
  • 24
    • 0029076718 scopus 로고
    • Priming of tumor-specific T cells in the draining lymph nodes after immunization with interleukin 2-secreting tumor cells: Three consecutive stages may be required for successful tumor vaccination
    • MAASS, G., SCHMIDT, W., BERGER, M., SCHILCHER, F., KOSZIK, F., SCHNEEBERGER, A., STINGL, G., BIRNSTIEL, M.L., and SCHWEIGHOFFER, T. (1995). Priming of tumor-specific T cells in the draining lymph nodes after immunization with interleukin 2-secreting tumor cells: three consecutive stages may be required for successful tumor vaccination. Proc. Natl. Acad. Sci. USA 92, 5540-5544.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5540-5544
    • Maass, G.1    Schmidt, W.2    Berger, M.3    Schilcher, F.4    Koszik, F.5    Schneeberger, A.6    Stingl, G.7    Birnstiel, M.L.8    Schweighoffer, T.9
  • 25
    • 0028809178 scopus 로고
    • Gene transfer as cancer therapy
    • DRANOFF, G., and MULLIGAN, R.C. (1995). Gene transfer as cancer therapy. Adv. Immunol. 58, 417-454.
    • (1995) Adv. Immunol. , vol.58 , pp. 417-454
    • Dranoff, G.1    Mulligan, R.C.2
  • 27
    • 0027598183 scopus 로고
    • Biological activity and in vivo clearance of antitumor antibody/cytokine fusion proteins
    • GILLIES, S.D., YOUNG, D., LO, K.M., and ROBERTS, S. (1993). Biological activity and in vivo clearance of antitumor antibody/cytokine fusion proteins. Bioconjug. Chem. 4, 230-235.
    • (1993) Bioconjug. Chem. , vol.4 , pp. 230-235
    • Gillies, S.D.1    Young, D.2    Lo, K.M.3    Roberts, S.4
  • 29
    • 0023269207 scopus 로고
    • Treatment of a murine B cell lymphoma with monoclonal antibodies and IL 2
    • BERINSTEIN, N., and LEVY, R. (1987). Treatment of a murine B cell lymphoma with monoclonal antibodies and IL 2. J. Immunol. 139, 971-976.
    • (1987) J. Immunol. , vol.139 , pp. 971-976
    • Berinstein, N.1    Levy, R.2
  • 30
    • 0023894032 scopus 로고
    • Specific enhancement of the therapeutic effect of anti-idiotype antibodies on a murine B cell lymphoma by IL-2
    • BERINSTEIN, N., STARNES, C.O., and LEVY, R. (1988). Specific enhancement of the therapeutic effect of anti-idiotype antibodies on a murine B cell lymphoma by IL-2. J. Immunol. 140, 2839-2845.
    • (1988) J. Immunol. , vol.140 , pp. 2839-2845
    • Berinstein, N.1    Starnes, C.O.2    Levy, R.3
  • 31
    • 0025733498 scopus 로고
    • Enhanced tumor uptake of macromolecules induced by a novel vasoactive interleukin 2 immunoconjugate
    • LEBERTHON, B., KHAWLI, L.A., ALAUDDIN, M., MILLER, G.K., CHARAK, B.S., MAZUMDER, A., and EPSTEIN, A.L. (1991). Enhanced tumor uptake of macromolecules induced by a novel vasoactive interleukin 2 immunoconjugate. Cancer Res. 51, 2694-2698.
    • (1991) Cancer Res. , vol.51 , pp. 2694-2698
    • Leberthon, B.1    Khawli, L.A.2    Alauddin, M.3    Miller, G.K.4    Charak, B.S.5    Mazumder, A.6    Epstein, A.L.7
  • 32
    • 0029854530 scopus 로고    scopus 로고
    • A chimeric Lym-1/interleukin 2 fusion protein for increasing tumor vascular permeability and enhancing antibody uptake
    • HU, P., HORNICK, J.L., GLASKY, M.S., YUN, A., MILKIE, M.N., KHAWLI, L.A., ANDERSON, P.M., and EPSTEIN, A.L. (1996). A chimeric Lym-1/interleukin 2 fusion protein for increasing tumor vascular permeability and enhancing antibody uptake. Cancer Res. 56, 4998-5004.
    • (1996) Cancer Res. , vol.56 , pp. 4998-5004
    • Hu, P.1    Hornick, J.L.2    Glasky, M.S.3    Yun, A.4    Milkie, M.N.5    Khawli, L.A.6    Anderson, P.M.7    Epstein, A.L.8
  • 33
    • 0028157381 scopus 로고
    • Treatment of neuroblastoma patients with antiganglioside GD2 antibody plus interleukin-2 induces antibody-dependent cellular cytotoxicity against neuroblastoma detected in vitro
    • HANK, J.A., SURFUS, J., GAN, J., CHEW, T.L., HONG, R., TANS, K., REISFELD, R., SEEGER, R.C., REYNOLDS, C.P., BAUER, M., et al. (1994). Treatment of neuroblastoma patients with antiganglioside GD2 antibody plus interleukin-2 induces antibody-dependent cellular cytotoxicity against neuroblastoma detected in vitro. J. Immunother. 15, 29-37.
    • (1994) J. Immunother. , vol.15 , pp. 29-37
    • Hank, J.A.1    Surfus, J.2    Gan, J.3    Chew, T.L.4    Hong, R.5    Tans, K.6    Reisfeld, R.7    Seeger, R.C.8    Reynolds, C.P.9    Bauer, M.10
  • 34
    • 0025877853 scopus 로고
    • Genetic construction and characterization of a fusion protein consisting of a chimeric F(ab′) with specificity for carcinomas and human IL-2
    • FELL, H.P., GAYLE, M.A., GROSMAIRE, L., and LEDBETTER, J.A. (1991). Genetic construction and characterization of a fusion protein consisting of a chimeric F(ab′) with specificity for carcinomas and human IL-2. J. Immunol. 146, 2446-2452.
    • (1991) J. Immunol. , vol.146 , pp. 2446-2452
    • Fell, H.P.1    Gayle, M.A.2    Grosmaire, L.3    Ledbetter, J.A.4
  • 35
    • 0026572996 scopus 로고
    • Antibody-targeted interleukin 2 stimulates T-cell killing of autologous tumor cells
    • GILLIES, S.D., REILLY, E.B., LO, K.M., and REISFELD, R.A. (1992). Antibody-targeted interleukin 2 stimulates T-cell killing of autologous tumor cells. Proc. Natl. Acad. Sci. USA 89, 1428-1432.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1428-1432
    • Gillies, S.D.1    Reilly, E.B.2    Lo, K.M.3    Reisfeld, R.A.4
  • 36
  • 37
    • 0028822038 scopus 로고
    • Construction, expression and characterisation of a single chain anti-tumour antibody (scFv)-IL-2 fusion protein
    • BOLETI, E., DEONARAIN, M.P., SPOONER, R.A., SMITH, A.J., EPENETOS, A.A., and GEORGE, A.J. (1995). Construction, expression and characterisation of a single chain anti-tumour antibody (scFv)-IL-2 fusion protein. Ann. Oncol. 6, 945-947.
    • (1995) Ann. Oncol. , vol.6 , pp. 945-947
    • Boleti, E.1    Deonarain, M.P.2    Spooner, R.A.3    Smith, A.J.4    Epenetos, A.A.5    George, A.J.6
  • 38
    • 0028856239 scopus 로고
    • Baculovirus expression of a functional single-chain immunoglobulin and its IL-2 fusion protein
    • BEI, R., SCHLOM, J., and KASHMIRI, S.V. (1995). Baculovirus expression of a functional single-chain immunoglobulin and its IL-2 fusion protein. J. Immunol. Methods 186, 245-255.
    • (1995) J. Immunol. Methods , vol.186 , pp. 245-255
    • Bei, R.1    Schlom, J.2    Kashmiri, S.V.3
  • 39
    • 0029346898 scopus 로고
    • An IgG3-IL-2 fusion protein activates complement, binds Fc gamma RI, generates LAK activity and shows enhanced binding to the high affinity IL-2R
    • HARVILL, E.T., and MORRISON, S.L. (1995). An IgG3-IL-2 fusion protein activates complement, binds Fc gamma RI, generates LAK activity and shows enhanced binding to the high affinity IL-2R. Immunotechnology 1, 95-105.
    • (1995) Immunotechnology , vol.1 , pp. 95-105
    • Harvill, E.T.1    Morrison, S.L.2
  • 40
    • 0030267660 scopus 로고    scopus 로고
    • In vivo properties of an IgG3-IL-2 fusion protein. a general strategy for immune potentiation
    • HARVILL, E.T., FLEMING, J.M., and MORRISON, S.L. (1996). In vivo properties of an IgG3-IL-2 fusion protein. A general strategy for immune potentiation. J. Immunol. 157, 3165-3170.
    • (1996) J. Immunol. , vol.157 , pp. 3165-3170
    • Harvill, E.T.1    Fleming, J.M.2    Morrison, S.L.3
  • 41
    • 0030221520 scopus 로고    scopus 로고
    • An IgG3-IL-2 fusion protein has higher affinity than hiIL-2 for the IL-2R alpha subunit: Real time measurement of ligand binding
    • HARVILL, E.T., and MORRISON, S.L. (1996). An IgG3-IL-2 fusion protein has higher affinity than hiIL-2 for the IL-2R alpha subunit: real time measurement of ligand binding. Mol. Immunol. 33, 1007-1014.
    • (1996) Mol. Immunol. , vol.33 , pp. 1007-1014
    • Harvill, E.T.1    Morrison, S.L.2
  • 42
    • 0028060152 scopus 로고
    • A recombinant antibody-interleukin 2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice
    • SABZEVARI, H., GILLIES, S.D., MUELLER, B.M., PANCOOK, J.D., and REISFELD, R.A. (1994). A recombinant antibody-interleukin 2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice. Proc. Natl. Acad. Sci. USA 91, 9626-9630.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 9626-9630
    • Sabzevari, H.1    Gillies, S.D.2    Mueller, B.M.3    Pancook, J.D.4    Reisfeld, R.A.5
  • 43
    • 0030007139 scopus 로고    scopus 로고
    • Eradication of established hepatic human neuroblastoma metastases in mice with severe combined immunodeficiency by antibody-targeted interleukin-2
    • PANCOOK, J.D., BECKER, J.C., GILLIES, S.D., and REISFELD, R.A. (1996). Eradication of established hepatic human neuroblastoma metastases in mice with severe combined immunodeficiency by antibody-targeted interleukin-2. Cancer Immunol. Immunother. 42, 88-92.
    • (1996) Cancer Immunol. Immunother. , vol.42 , pp. 88-92
    • Pancook, J.D.1    Becker, J.C.2    Gillies, S.D.3    Reisfeld, R.A.4
  • 44
    • 0030453784 scopus 로고    scopus 로고
    • Long-lived and transferable tumor immunity in mice after targeted interleukin-2 therapy
    • BECKER, J.C., VARKI, N., GILLIES, S.D., FURUKAWA, K., and REISFELD, R.A. (1996). Long-lived and transferable tumor immunity in mice after targeted interleukin-2 therapy. J. Clin. Invest. 98, 2801-2804.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2801-2804
    • Becker, J.C.1    Varki, N.2    Gillies, S.D.3    Furukawa, K.4    Reisfeld, R.A.5
  • 45
    • 0029836763 scopus 로고    scopus 로고
    • An antibody-interleukin 2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response
    • BECKER, J.C., VARKI, N., GILLIES, S.D., FURUKAWA, K., and REISFELD, R.A. (1996). An antibody-interleukin 2 fusion protein overcomes tumor heterogeneity by induction of a cellular immune response. Proc. Natl. Acad. Sci. USA 93, 7826-7831.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7826-7831
    • Becker, J.C.1    Varki, N.2    Gillies, S.D.3    Furukawa, K.4    Reisfeld, R.A.5
  • 46
    • 0029890827 scopus 로고    scopus 로고
    • T cell-mediated eradication of murine metastatic melanoma induced by targeted interleukin 2 therapy
    • BECKER, J.C., PANCOOK, J.D., GILLIES, S.D., FURUKAWA, K., and REISFELD, R.A. (1996). T cell-mediated eradication of murine metastatic melanoma induced by targeted interleukin 2 therapy. J. Exp. Med. 183, 2361-2366.
    • (1996) J. Exp. Med. , vol.183 , pp. 2361-2366
    • Becker, J.C.1    Pancook, J.D.2    Gillies, S.D.3    Furukawa, K.4    Reisfeld, R.A.5
  • 47
    • 0029866441 scopus 로고    scopus 로고
    • Eradication of human hepatic and pulmonary melanoma metastases in SCID mice by antibody-interleukin 2 fusion proteins
    • BECKER, J.C., PANCOOK, J.D., GILLIES, S.D., MENDELSOHN, J., and REISFELD, R.A. (1996). Eradication of human hepatic and pulmonary melanoma metastases in SCID mice by antibody-interleukin 2 fusion proteins. Proc. Natl. Acad. Sci. USA 93, 2702-2707.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2702-2707
    • Becker, J.C.1    Pancook, J.D.2    Gillies, S.D.3    Mendelsohn, J.4    Reisfeld, R.A.5
  • 48
    • 0022398764 scopus 로고
    • Monoclonal anti-idiotype antibodies against the murine B cell lymphoma 38C13: Characterization and use as probes for the biology of the tumor in vivo and in vitro
    • MALONEY, D.G., KAMINSKI, M.S., BUROWSKI, D., HAIMOVICH, I., and LEVY, R. (1985). Monoclonal anti-idiotype antibodies against the murine B cell lymphoma 38C13: characterization and use as probes for the biology of the tumor in vivo and in vitro. Hybridoma 4, 191-209.
    • (1985) Hybridoma , vol.4 , pp. 191-209
    • Maloney, D.G.1    Kaminski, M.S.2    Burowski, D.3    Haimovich, I.4    Levy, R.5
  • 49
    • 0022619734 scopus 로고
    • Importance of antibody isotype in monoclonal anti-idiotype therapy of a murine B cell lymphoma. A study of hybridoma class switch variants
    • KAMINSKI, M.S., KITAMURA, K., MALONEY, D.G., CAMPBELL, M.J., and LEVY, R. (1986). Importance of antibody isotype in monoclonal anti-idiotype therapy of a murine B cell lymphoma. A study of hybridoma class switch variants. J. Immunol. 136, 1123-1130.
    • (1986) J. Immunol. , vol.136 , pp. 1123-1130
    • Kaminski, M.S.1    Kitamura, K.2    Maloney, D.G.3    Campbell, M.J.4    Levy, R.5
  • 50
    • 0017649604 scopus 로고    scopus 로고
    • An IgM-producing tumor with biochemical characteristics of a small B lymphocyte
    • BERGMAN, Y., HAIMOVICH, J., and MELCHERS, F. (1997). An IgM-producing tumor with biochemical characteristics of a small B lymphocyte. Eur. J. Immunol. 7, 574-579.
    • (1997) Eur. J. Immunol. , vol.7 , pp. 574-579
    • Bergman, Y.1    Haimovich, J.2    Melchers, F.3
  • 51
    • 0017684604 scopus 로고
    • Characterization of a carcinogen-induced murine B lymphocyte cell line of C3H/eB origin
    • BERGMAN, Y., and HAIMOVICH, J. (1977). Characterization of a carcinogen-induced murine B lymphocyte cell line of C3H/eB origin. Eur. J. Immunol. 7, 413-417.
    • (1977) Eur. J. Immunol. , vol.7 , pp. 413-417
    • Bergman, Y.1    Haimovich, J.2
  • 52
    • 0020507372 scopus 로고
    • Immunotherapy of a murine B cell tumor with antibodies and F(ab')2 fragments against idiotypic determinants of its cell surface IgM
    • PEREK, Y., HURWITZ, E., BUROWSKI, D., and HAIMOVICH, J. (1983). Immunotherapy of a murine B cell tumor with antibodies and F(ab')2 fragments against idiotypic determinants of its cell surface IgM. J. Immunol. 131, 1600-1603.
    • (1983) J. Immunol. , vol.131 , pp. 1600-1603
    • Perek, Y.1    Hurwitz, E.2    Burowski, D.3    Haimovich, J.4
  • 53
    • 0024842885 scopus 로고
    • Production and properties of chimeric antibody molecules
    • SHIN, S.U., and MORRISON, S.L. (1989). Production and properties of chimeric antibody molecules. Methods Enzymol. 178, 459-476.
    • (1989) Methods Enzymol. , vol.178 , pp. 459-476
    • Shin, S.U.1    Morrison, S.L.2
  • 54
    • 0022446735 scopus 로고
    • Limitations of radiolabeled monoclonal antibodies for localization of human neoplasms
    • EPENETOS, A.A., SNOOK, D., DURBIN, H., JOHNSON, P.M., and TAYLOR, P.J. (1986). Limitations of radiolabeled monoclonal antibodies for localization of human neoplasms. Cancer Res. 46, 3183-3191.
    • (1986) Cancer Res. , vol.46 , pp. 3183-3191
    • Epenetos, A.A.1    Snook, D.2    Durbin, H.3    Johnson, P.M.4    Taylor, P.J.5
  • 55
    • 0025014962 scopus 로고
    • Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors
    • JAIN, R.K. (1990). Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors. Cancer Res. 50, S814-S819.
    • (1990) Cancer Res. , vol.50
    • Jain, R.K.1
  • 56
    • 0001033891 scopus 로고
    • Factors for improving monoclonal-antibody targeting
    • MURRAY, J.L. (1992). Factors for improving monoclonal-antibody targeting. Diagn. Oncol. 2, 234-241.
    • (1992) Diagn. Oncol. , vol.2 , pp. 234-241
    • Murray, J.L.1
  • 57
    • 0027400274 scopus 로고
    • Monoclonal antibodies in cancer detection and therapy
    • GOLDENBERG, D.M. (1993). Monoclonal antibodies in cancer detection and therapy. Am. J. Med. 94, 297-312.
    • (1993) Am. J. Med. , vol.94 , pp. 297-312
    • Goldenberg, D.M.1
  • 58
    • 0027464742 scopus 로고
    • Uses and limitations of monoclonal antibodies (MoAbs) in the treatment of malignant disease: A review
    • KEMSHEAD, J.T., and HOPKINS, K. (1993). Uses and limitations of monoclonal antibodies (MoAbs) in the treatment of malignant disease: a review. J. R. Soc. Med. 86, 219-224.
    • (1993) J. R. Soc. Med. , vol.86 , pp. 219-224
    • Kemshead, J.T.1    Hopkins, K.2
  • 59
    • 0025362254 scopus 로고
    • Radiolabelled monoclonal antibodies in tumour diagnosis and therapy
    • KOSMAS, C., KALOFONOS, H.P., and EPENETOS, A.A. (1990). Radiolabelled monoclonal antibodies in tumour diagnosis and therapy. Dev. Biol. Stand. 71, 93-102.
    • (1990) Dev. Biol. Stand. , vol.71 , pp. 93-102
    • Kosmas, C.1    Kalofonos, H.P.2    Epenetos, A.A.3
  • 61
    • 0023232810 scopus 로고
    • Pharmacokinetics and antibodies
    • GOODWIN, D.A. (1987). Pharmacokinetics and antibodies. J. Nucl. Med. 28, 1358-1362.
    • (1987) J. Nucl. Med. , vol.28 , pp. 1358-1362
    • Goodwin, D.A.1
  • 62
    • 0023521040 scopus 로고
    • Radioimmunotherapy of cancer: Clinical studies and limiting factors
    • DYKES, P.W., BRADWELL, A.R., CHAPMAN, C.E., and VAUGHAN, A.T. (1987). Radioimmunotherapy of cancer: clinical studies and limiting factors. Cancer Treat. Rev. 14, 87-106.
    • (1987) Cancer Treat. Rev. , vol.14 , pp. 87-106
    • Dykes, P.W.1    Bradwell, A.R.2    Chapman, C.E.3    Vaughan, A.T.4
  • 63
    • 0023912404 scopus 로고
    • Targeting of cancer with radiolabeled antibodies. Prospects for imaging and therapy
    • GOLDENBERG, D.M. (1988). Targeting of cancer with radiolabeled antibodies. Prospects for imaging and therapy. Arch. Pathol. Lab. Med. 112, 580-587.
    • (1988) Arch. Pathol. Lab. Med. , vol.112 , pp. 580-587
    • Goldenberg, D.M.1
  • 64
    • 0029112529 scopus 로고
    • Reevaluation of the superiority of polyethylene glycol-modified interleukin-2 over regular recombinant interleukin-2
    • BERNSEN, M.R., DULLENS, H.F., DEN OTTER, W., and HEINTZ, P.M. (1995). Reevaluation of the superiority of polyethylene glycol-modified interleukin-2 over regular recombinant interleukin-2. J. Interferon Cytokine Res. 15, 641-645.
    • (1995) J. Interferon Cytokine Res. , vol.15 , pp. 641-645
    • Bernsen, M.R.1    Dullens, H.F.2    Den Otter, W.3    Heintz, P.M.4
  • 65
    • 0026748230 scopus 로고
    • Polyethylene-glycol-modified interleukin-2 is superior to interleukin-2 in locoregional immunotherapy of established guinea-pig tumors
    • MATTIJSSEN, V., BALEMANS, L.T.M., STEERENBERG, P.A., and DEMULDER, P.H.M. (1992). Polyethylene-glycol-modified interleukin-2 is superior to interleukin-2 in locoregional immunotherapy of established guinea-pig tumors. Int. J. Cancer 51, 812-817.
    • (1992) Int. J. Cancer , vol.51 , pp. 812-817
    • Mattijssen, V.1    Balemans, L.T.M.2    Steerenberg, P.A.3    Demulder, P.H.M.4
  • 66
    • 0024388928 scopus 로고
    • Schedule dependency of the antitumor activity and toxicity of polyethylene glycol-modified interleukin 2 in murine tumor models
    • ZIMMERMAN, R.J., AUKERMAN, S.L., KATRE, N.V., WINKELHAKE, J.L., and YOUNG, J.D. (1989). Schedule dependency of the antitumor activity and toxicity of polyethylene glycol-modified interleukin 2 in murine tumor models. Cancer Res. 49, 6521-6528.
    • (1989) Cancer Res. , vol.49 , pp. 6521-6528
    • Zimmerman, R.J.1    Aukerman, S.L.2    Katre, N.V.3    Winkelhake, J.L.4    Young, J.D.5
  • 67
    • 0001365675 scopus 로고
    • Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model
    • KATRE, N.V., KNAUF, M.J., and LAIRD, W.J. (1987). Chemical modification of recombinant interleukin 2 by polyethylene glycol increases its potency in the murine Meth A sarcoma model. Proc. Natl. Acad. Sci. USA 84, 1487-1491.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 1487-1491
    • Katre, N.V.1    Knauf, M.J.2    Laird, W.J.3
  • 68
    • 0025315922 scopus 로고
    • Lymphokine gene therapy for cancer
    • RUSSELL, S.J. (1990). Lymphokine gene therapy for cancer [see Comments]. Immunol. Today 11, 196-200.
    • (1990) Immunol. Today , vol.11 , pp. 196-200
    • Russell, S.J.1
  • 69
    • 0025000864 scopus 로고
    • Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity
    • GANSBACHER, B., ZIER, K., DANIELS, B., CRONIN, K., BANNERJI, R., and GILBOA, E. (1990). Interleukin 2 gene transfer into tumor cells abrogates tumorigenicity and induces protective immunity. J. Exp. Med. 172, 1217-1224.
    • (1990) J. Exp. Med. , vol.172 , pp. 1217-1224
    • Gansbacher, B.1    Zier, K.2    Daniels, B.3    Cronin, K.4    Bannerji, R.5    Gilboa, E.6
  • 71
    • 0027056895 scopus 로고
    • Alterations is signal transduction molecules in T lymphocytes from tumor-bearing mice
    • MIZOGUCHI, H., O'SHEA, J.J., LONGO, D.L., LOEFFLER, C.M., McVICAR, D.W., and OCHOA, A.C. (1992). Alterations is signal transduction molecules in T lymphocytes from tumor-bearing mice [see Comments]. Science 258, 1795-1798.
    • (1992) Science , vol.258 , pp. 1795-1798
    • Mizoguchi, H.1    O'Shea, J.J.2    Longo, D.L.3    Loeffler, C.M.4    McVicar, D.W.5    Ochoa, A.C.6
  • 72
    • 0030159358 scopus 로고    scopus 로고
    • Strain differences in the cytotoxic activity and TNF production of murine macrophages stimulated by lentinan
    • KERÉKGYART, C., VIRAG, L., TANK, L., CHIHARA, G., and FACHET, J. (1996). Strain differences in the cytotoxic activity and TNF production of murine macrophages stimulated by lentinan. Int. J. Immunopharmacol. 128, 347-353.
    • (1996) Int. J. Immunopharmacol. , vol.128 , pp. 347-353
    • Kerékgyart, C.1    Virag, L.2    Tank, L.3    Chihara, G.4    Fachet, J.5
  • 73
    • 0027486829 scopus 로고
    • Production of cytokines by mouse peritoneal cells treated with Topa Torf Preparation (TTP): Dependence on age and strain of mice
    • BOACH-OLSZEWSKA, Z., ZACZYNSKA, E., BRONIAREK, E., and INGLOT, A.D. (1993). Production of cytokines by mouse peritoneal cells treated with Topa Torf Preparation (TTP): dependence on age and strain of mice. Arch. Immunol. Ther. Exp. (Warsz.) 41, 81-85.
    • (1993) Arch. Immunol. Ther. Exp. (Warsz.) , vol.41 , pp. 81-85
    • Boach-Olszewska, Z.1    Zaczynska, E.2    Broniarek, E.3    Inglot, A.D.4
  • 74
    • 0027674905 scopus 로고
    • Evidence for genetic basis of seasonal differences in antibody formation between two mouse strains
    • RATAJCZAK, H.V., THOMAS, P.T., SOTHERN, R.B., VOLLMUTH, T., and HECK, J.D. (1993). Evidence for genetic basis of seasonal differences in antibody formation between two mouse strains. Chronobiol. Int. 10, 383-394.
    • (1993) Chronobiol. Int. , vol.10 , pp. 383-394
    • Ratajczak, H.V.1    Thomas, P.T.2    Sothern, R.B.3    Vollmuth, T.4    Heck, J.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.