High frequency of CagA + Helicobacter pylori infection in high-grade gastric MALT B-cell lymphomas

Journal of Pathology

Volumn 185, Issue 4, 1998, Pages 409-412

  Peng, Huaizheng ^a   Ranaldi, Renzo ^b   Diss, Tim C ^a   Isaacson, Peter G ^a   Bearzi, Italo ^b   Pan, Langxing ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b Ospedale Regionale Torrette   (Italy)

Author keywords

CagA; H. pylori; MALT lymphoma; PCR

Indexed keywords

ARTICLE; B CELL LYMPHOMA; BACTERIAL INFECTION; CARCINOGENESIS; CONTROLLED STUDY; GASTRITIS; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; INCIDENCE; ITALY; MALIGNANT TRANSFORMATION; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STOMACH BIOPSY; STOMACH LYMPHOMA;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CHRONIC DISEASE; GASTRITIS; GENES, BACTERIAL; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; LYMPHOMA, HIGH-GRADE; LYMPHOMA, MUCOSA-ASSOCIATED LYMPHOID TISSUE; POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS;

EID: 0031869537     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199808)185:4<409::AID-PATH121>3.0.CO;2-T     Document Type: Article

References (34)

1. Wotherspoon AC, Ortiz Hidalgo C, Falzon MR, Isaacson PG. Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma [see Comments]. Lancet 1991; 338: 1175-1176.
2. Isaacson PG, Spencer J. Gastric lymphoma and Helicobacter pylori. Important Adv Oncol 1996; 2: 111-121.
3. Hussell T, Isaacson PG, Crabtree JE, Spencer J. The response of cells from low-grade B-cell gastric lymphomas of mucosa-associated lymphoid tissue to Helicobacter pylori. Lancet 1993; 342: 571-574.
4. Hussell T, Isaacson PG, Crabtree JE, Spencer J. Helicobactr pylori-specific tumour-infiltrating T-cells provide contact-dependent help for the growth of malignant B-cells in low-grade gastric lymphoma of mucosa-associated lymphoid tissue. J Pathol 1996; 178: 122-127.
5. Crabtree JE, Spencer J. Immunologic aspects of Helicobacter pylori infection and malignant transformation of B cells. Semin Gastrointest Dis 1996; 7: 30-40.
6. Figura N. Progress in defining the inflammatory cascade. Eur J Gastroenterol Hepatol 1995; 7: 296-302.
7. Stark RM, Greenman J, Millar MR. Physiology and biochemistry of Helicobacter pylori. Br J Biomed Sci 1995; 52: 282-290.
8. Covacci A, Censini S, Bugnoli M, et al. Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer. Proc Natl Acad Sci USA 1993; 90: 5791-5795.
9. Kuipers EJ, Perez Perez GI, Meuwissen SG, Blaser MJ. Helicobacter pylori and atrophic gastritis: importance of the cagA status [see Comments]. J Natl Cancer Inst 1995; 87: 1777-1780.
10. Kuipers EJ, Thijs JC, Festen HP. The prevalence of Helicobacter pylori in peptic ulcer disease. Aliment Pharmacol Ther 1995; 9 (Suppl. 2): 59-69.
11. Kuipers EJ. Helicobacter pylori and the risk and management of associated diseases: gastritis, ulcer disease, atrophic gastritis and gastric cancer. Aliment Pharmacol Ther 1997; 11 (Suppl. 1): 71-88.
12. Blaser MJ, Perez Perez GI, Kleanthous H, et al. Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach. Cancer Res 1995; 55: 2111-2115.
13. Crabtree JE, Farmery SM. Heltcobacter-pylori and gastric-mucosal cytokines - evidence that CagA-positive strains are more virulent. Lab Invest 1995; 73: 742-745.
14. Censini S, Lange C, Xiang Z, et al. Cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors. Proc Natl Acad Sci USA 1996; 93: 14 648-14 653.
15. Crabtree JE, Xiang Z, Lindley IJ, Tompkins DS, Rappuoli R, Covacci A. Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori. J Clin Pathol 1995; 48: 967-969.
16. Crabtree JE, Covacci A, Farmery SM, et al. Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype. J Clin Pathol 1995; 48: 41-45.
17. Crabtree JE, Farmery SM, Lindley IJ, Figura N, Peichl P, Tompkins DS. CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell lines. J Clin Pathol 1994; 47: 945-950.
18. Cerutti PA, Trump BF. Inflammation and oxidative stress in carcinogenesis. Cancer Cells 1991; 3: 1-7.
19. Eck M, Schmausser B, Haas R, Greiner A, Czub S, Muller Hermelink HK. MALT-type lymphoma of the stomach is associated with Helicobacter pylori strains expressing the CagA protein. Gastroenterology 1997; 112: 1482-1486.
20. de Jong D, van der Hulst RW, Pals G, et al. Gastric non-Hodgkin lymphomas of mucosa-associated lymphoid tissue are not associated with more aggressive Helicobacter pylori strains as identified by CagA [see Comments]. Am J Clin Pathol 1996; 106: 670-675.
21. Isaacson PG. Recent developments in our understanding of gastric lymphomas. Am J Surg Pathol 1996; 20 (Suppl. 1): S1-S7.
22. Isaacson PG, Spencer J. The biology of low grade MALT lymphoma. J Clin Pathol 1995; 48: 395-397.
23. Diss TC, Peng HZ, Wotherspoon AC, Isaacson PG, Pan L. Detection of monoclonality in low-grade B-cell lymphomas using the polymerase chain reaction is dependent on primer selection and lymphoma type. J Pathol 1993; 169: 291-295.
24. Wotherspoon AC, Doglioni C, Diss TC, et al. Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet 1993; 342: 575-577.
25. Atherton JC, Cao P, Peek RM Jr, Tummuru MK, Blaser MJ, Cover TL. Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Associ• ation of specific vacA types with cytotoxin production and peptic ulceration. J Biol Chem 1995; 270: 17 771-17 777.
26. Peek RM Jr, Miller GG, Tham KT, et al. Detection of Helicobacter pylori gene expression in human gastric mucosa. J Clin Microbiol 1995; 33: 28-32.
27. Isaacson PG. Recent advances in the biology of lymphomas. Eur J Cancer 1991; 27: 795-802.
28. Isaacson PG. Extranodal lymphomas: the MALT concept. Verh Dtsch Ges Pathol 1992; 76: 14-23.
29. Isaacson PG, Wright DH. Extranodal lymphoma. In: Anthony PP, Macsween RNM, eds. Recent Advances in Histopathology. Edinburgh: Churchill Livingstone, 1987; 159-184.
30. Genta RM, Hamner HW, Graham DY. Gastric lymphoid follicles in Helicobacter pylori infection: frequency, distribution, and response to triple therapy. Hum Pathol 1993; 24: 577-583.
31. Blaser MJ. Helicobacter pylori phenotypes associated with peptic ulceration. Scand J Gastroenterol Suppl 1994; 205: 1-5.
32. Cheng KC, Diaz MO. Genomic instability and cancer: cause and effect. Cancer Cells 1991; 3: 188-192.
33. Du MQ, Peng HZ, Singh N, Isaacson PG, Pan LX. The accumulation of p53 abnormality is associated with progression of mucosa-associated lymphoid tissue lymphoma. Blood 1995: 86: 4587-4593.
34. Peng HZ, Chen G, Du MQ, Singh N, Isaacson PG, Pan LX. Replication error (RER) and p53 gene mutation in lymphomas of mucosa-associated lymphoid tissue (MALT). Am J Pathol 1996; 148: 643-648.