Abnormality of alpha-adrenergic vascular response in patients with neurally mediated syncope

American Journal of Cardiology

Volumn 82, Issue 4, 1998, Pages 438-443

  Ono, Takuya ^a   Saitoh, Hirokazu ^a   Atarashi, Hirotsugu ^a   Hayakawa, Hirokazu ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; ISOPRENALINE; PHENTOLAMINE; PHENYLEPHRINE; PROPRANOLOL;

ADULT; AGED; ALPHA ADRENERGIC STIMULATION; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BLOOD VESSEL REACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HEAD TILTING; HEMODYNAMICS; HUMAN; MALE; NERVE BLOCK; PRIORITY JOURNAL; SYNCOPE; SYSTOLIC BLOOD PRESSURE;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ADRENERGIC BETA-ANTAGONISTS; ADULT; AGED; ANTI-ARRHYTHMIA AGENTS; ATROPINE; AUTONOMIC NERVOUS SYSTEM; ECHOCARDIOGRAPHY; FEMALE; HEMODYNAMIC PROCESSES; HUMANS; MALE; MIDDLE AGED; PHENTOLAMINE; PHENYLEPHRINE; PROPRANOLOL; SYNCOPE; TILT-TABLE TEST; VASCULAR RESISTANCE;

EID: 0031869077     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9149(98)00358-0     Document Type: Article

References (30)

1. Kenny RA, Ingram A, Bayliss J, Sutton R. Head-up tilt: a useful test for investigating unexplained syncope. Lancet 1986;1:1352-1354.
2. Abboud FM. Ventricular syncope Is the heart a sensory organ? N Engl J Med 1989;320:390-392.
3. Thames MD, Donald DE, Shepherd JT. Behavior of cardiac receptors with nonmyelinated vagal afferents during spontaneous respiration in cats. Circ Res 1977;41:694-701.
4. Lieshout JJ, Wieling W, Karemaker JM, Eckberg DL. The vasovagal response. Clin Sci 1991;81:575-586.
5. Chen MY, Goldenberg IF, Milstein S, Buetikofer J, Almquist A, Lesser J, Benditt DG. Cardiac electrophysiologic and hemodynamic correlates of neurally mediated syncope. Am J Cardiol 1989;63:66-72.
6. Thoren P. Role of cardiac vagal C-fibers in cardiovascular control. Rev Physiol Biochem Pharmacol 1979;86:1-94.
7. Abi-Samra F, Maloney JD, Fouad-Tarazi FM, Castle LW. The usefulness of head-up tilt testing and hemodynamic investigations in the workup of syncope of unknown origin. PACE 1988;11:1202-1214.
8. Thomson HL, Lele SS, Atherton JJ, Wright KN, Stafford W, Frenneaux MP. Abnormal forearm vascular responses during dynamic leg exercise in patients with vasovagal syncope. Circulation 1995;92:2204-2209.
9. Thomson HL, Wright K, Frenneaux M. Baroreflex sensitivity in patients with vasovagal syncope. Circulation 1997;95:395-400.
10. Sneddon JF, Counihan PJ, Bashir Y, Haywood GA, Ward DE, Camm AJ. Assessment of autonomic function in patients with neurally mediated syncope: augmented cardiopulmonary baroreceptor responses to graded orthostatic stress. J Am Coll Cardiol 1993;21:1193-1198
11. Almquist A, Goldenberg IF, Milstein S, Chen MY, Chen X, Hansen R, Gornick CC, Benditt DG. Provocation of bradycardia and hypotension by isoproterenol and upright posture in patients with unexplained syncope. N Engl J Med 1989;320:346-351.
12. Mark AL. The Bezold-Jarisch reflex revisited: clinical implications of inhibitory reflexes originating in the heart. J Am Coll Cardiol 1983;1:90-102.
13. Sgarbossa EB, Pinski SL, Jaeger FJ, Trohman RG, Maloney JD. Incidence and predictors of syncope in paced patients with sick sinus syndrome. PACE 1992:15:2055-2060.
14. Fitzpatrick AP, Banner N, Cheng A, Yacoub M, Sutton R. Vasovagal reaction may occur after orthotopic heart transplantation. J Am Coll Cardiol 1993;21:1132-1137.
15. Ono T, Nomura A, Someya T, Matsumoto S, Miyauchi Y, Osaka M, Sasabe N, Saitoh H, Ino T, Atarashi H, Katoh T, Hayakawa H. Alpha-adrenergic vascular response in the patients with cardiac arrhythmia (abstr). Circulation 1994;90: (suppl I):I-55.
16. Sutton R, Peterson M, Brignole M, Raviele A, Menozzi C, Giani P. Proposed classification for tilt induced vasovagal syncope. Eur J Cardiac Pacing Electrophysiol 1992;3:180-183.
17. Jose AD. Effect of combined sympathetic and parasympathetic blockade on heart rate and cardiac function in man. Am J Cardiol 1966;18:476-478.
18. Sneddon JF, Counihan PJ, Bashir Y, Haywood GA, Ward DE, Camm AJ. Impaired immediate vasoconstrictor responses in patients with recurrent neurally mediated syncope. Am J Cardiol 1993;71:72-76.
19. Morillo CA, Leitch JW, Yee R, Klein GJ. A placebo-controlled trial of intravenous and oral disopyramide for prevention of neurally mediated syncope induced by head-up tilt. J Am Coll Cardiol 1993;22:1843-1848.
20. Cox MM, Perlman BA, Mayor MR, Silberstein TA, Levin E, Pringle L, Castellanos A, Myerburg RJ. Acute and long-term beta-adrenergic blockade for patients with neurocardiogenic syncope. J Am Coll Cardiol 1995;26:1293-1298.
21. Leor J, Rotstein Z, Vered Z, Kaplinsky E, Truman S, Eldar M. Absence of tachycardia during tilt test predicts failure of β-blocker therapy in patients with neurocardiogenic syncope. Am Heart J 1994;127:1539-1543.
22. Sra J, Maglio C, Biehl M, Dhala A, Blanck Z, Deshpande S, Jazayeri MR, Akhtar M. Efficacy of midodrine hydrochloride in neurocardiogenic syncope refractory to standard therapy. J Cardiovasc Electrophysiol 1997;8:42-46.
23. Zachariah PK, Bloedow DC, Moyer TP, Sheps SG, Schirger A, Fealey RD. Pharmacodynamics of midodrine, an antihypotensive agent. Clin Pharmacol Ther 1986;39:586-591.
24. Koyama S, Matsubara T, Aizawa Y, Ohshima M, Yamaguchi T, Yamazaki Y, Igarashi Y, Tamura Y, Yamazoe M, Izumi T, Shibata A, Tanaka Y, Watanabe K. A case of vasovagal syncope with convulsions-the effects of midodrine hydrochloride. Jpn Circ J 1992;56:950-954.
25. Raviele A, Gasparini G, DiPede F, Bonso A, Piccole E. Usefulness of head-up tilt test in evaluating patients with syncope of unknown origin and negative electrophysiologic study. Am J Cardiol 1990;65:1322-1327.
26. Herndon CW, Sagawa K. Combined effects of aortic and right atrial pressures on aortic flow. Am J Physiol 1969;217:65-72.
27. Zener J, Harrison DC. Circulatory actions of phentolamine before and after autonomic blockade. Cardiovasc Res 1973;7:748-754.
28. Saitoh H, Nomura A, Osaka M, Sasabe N, Atarashi H, Hayakawa H. Developmental changes of alphal-adrenergic chronotropic action on human sinus node. Am J Cardiol 1995;76:89-91.
29. Grubb BP, Wolfe D, Temesy-Armos P, Hahn H, Elliott L. Reproducibility of head upright tilt table test results in patients with syncope. PACE 1992;15:1477-1481.
30. Sheldon R, Splawinski J, Killam S. Reproducibility of isoproterenol tilt-table tests in patients with syncope. Am J Cardiol 1992;69:1300-1305.