메뉴 건너뛰기




Volumn 18, Issue 4 A, 1998, Pages 2623-2630

In vitro and in vivo antiproliferative activity of IPCAP, a new pyrazole nucleoside analog

Author keywords

Antitumor chemotherapy; Novel antiproliferative agents

Indexed keywords

CYTARABINE; DOXORUBICIN; FLUOROURACIL; GUANOSINE PHOSPHATE; INOSINE PHOSPHATE; MERCAPTOPURINE; METHOTREXATE; NUCLEOSIDE ANALOG; PACLITAXEL; PYRAZOLE; RIBAVIRIN; TIAZOFURIN; TIOGUANINE;

EID: 0031868541     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (8)

References (33)
  • 1
    • 0025643036 scopus 로고
    • The clinical relevance of multidrug resistance
    • Bellamy WT, Dalton WS, Dorr RT: The clinical relevance of multidrug resistance. Cancer Invest 8: 547-562, 1990.
    • (1990) Cancer Invest , vol.8 , pp. 547-562
    • Bellamy, W.T.1    Dalton, W.S.2    Dorr, R.T.3
  • 2
    • 0025292458 scopus 로고
    • A facile synthesis of certain 4- and 4,5-disubstituted 1-ß-D-ribofuranosylpyrazoles
    • Bhattacharya BK, Robins RK, Revankar GR: A facile synthesis of certain 4- and 4,5-disubstituted 1-ß-D-ribofuranosylpyrazoles. J Heterocyclic Chem 127: 795-783, 1990.
    • (1990) J Heterocyclic Chem , vol.127 , pp. 795-1783
    • Bhattacharya, B.K.1    Robins, R.K.2    Revankar, G.R.3
  • 3
    • 0021824479 scopus 로고
    • Biochemical and antitumor activity of tiazofurin and its selenium analog 2-ß-D-ribofuranosyl-4- selenazole-carboxamide
    • Boritzki TJ, Berry DA, Besserer JA, Dancook P, Fry DW, Leopold WR and Jackson RC: Biochemical and antitumor activity of tiazofurin and its selenium analog 2-ß-D-ribofuranosyl-4-selenazole-carboxamide. Biochem Pharmacol 34: 1109-1114, 1985.
    • (1985) Biochem Pharmacol , vol.34 , pp. 1109-1114
    • Boritzki, T.J.1    Berry, D.A.2    Besserer, J.A.3    Dancook, P.4    Fry, D.W.5    Leopold, W.R.6    Jackson, R.C.7
  • 5
    • 0019953349 scopus 로고
    • The conversion of 2-ß-D-ribofuranosyl-thiazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase inhibitory properties
    • Cooney DA, Jayaram HN, Gebeyehu G, Betts CR, Kelley JA, Marquez VE And Johns DG: The conversion of 2-ß-D-ribofuranosyl-thiazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase inhibitory properties. Biochem Pharmacol 31: 2133-2136, 1982.
    • (1982) Biochem Pharmacol , vol.31 , pp. 2133-2136
    • Cooney, D.A.1    Jayaram, H.N.2    Gebeyehu, G.3    Betts, C.R.4    Kelley, J.A.5    Marquez, V.E.6    Johns, D.G.7
  • 6
    • 0022445670 scopus 로고
    • Rapid colorimetric assay for cell growth and survival
    • Denizot F and Lang R: Rapid colorimetric assay for cell growth and survival. J Immunol Methods 89: 271-277, 1986.
    • (1986) J Immunol Methods , vol.89 , pp. 271-277
    • Denizot, F.1    Lang, R.2
  • 8
    • 0023792382 scopus 로고
    • Combined modalities of resistance in etoposide-resistant human KB cell lines
    • Ferguson PJ, Fisher MH, Stephenson J, Li D, Zhou B, Cheng Y: Combined modalities of resistance in etoposide-resistant human KB cell lines. Cancer Res 48: 5956-5964, 1988.
    • (1988) Cancer Res , vol.48 , pp. 5956-5964
    • Ferguson, P.J.1    Fisher, M.H.2    Stephenson, J.3    Li, D.4    Zhou, B.5    Cheng, Y.6
  • 9
    • 0026661080 scopus 로고
    • Synthesis and antiviral evaluation of N-carboxamidine-substituted analogues of 1-ß-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine hydrochloride
    • Gabrielsen B, Phelan MJ, See C, Huggins JW, Kefauver DF, Monath TP, Ussey MA: Synthesis and antiviral evaluation of N-carboxamidine-substituted analogues of 1-ß-D-ribofuranosyl-1,2,4-triazole-3-carboxamidine hydrochloride. J Med Chem 35: 3231-38, 1992.
    • (1992) J Med Chem , vol.35 , pp. 3231-3238
    • Gabrielsen, B.1    Phelan, M.J.2    See, C.3    Huggins, J.W.4    Kefauver, D.F.5    Monath, T.P.6    Ussey, M.A.7
  • 10
    • 0020567631 scopus 로고
    • Synthesis of tiazole-4-carboxamide adenine dinucleotide. a powerfull inhibitor of IMP dehydrogenase
    • Gebeyehu G, Marquez VE, Kelley JA, Cooney DA, Jayaram HN and Johns DG: Synthesis of tiazole-4-carboxamide adenine dinucleotide. A powerfull inhibitor of IMP dehydrogenase. J Med Chem 26: 922-925, 1983.
    • (1983) J Med Chem , vol.26 , pp. 922-925
    • Gebeyehu, G.1    Marquez, V.E.2    Kelley, J.A.3    Cooney, D.A.4    Jayaram, H.N.5    Johns, D.G.6
  • 11
    • 0025773889 scopus 로고
    • Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the anti-human immunodeficiency virus nucleotides 2'-3'-dideoxyadenosine and 2'-3'-dideoxyinosine
    • Hartman NR, Ahluwalia GS, Cooney DA, Mitsuya H, Kageyama S, Fridland A, Broder S, Johns DG: Inhibitors of IMP dehydrogenase stimulate the phosphorylation of the anti-human immunodeficiency virus nucleotides 2'-3'-dideoxyadenosine and 2'-3'-dideoxyinosine. Molecular Pharmacol 40: 118-124, 1991.
    • (1991) Molecular Pharmacol , vol.40 , pp. 118-124
    • Hartman, N.R.1    Ahluwalia, G.S.2    Cooney, D.A.3    Mitsuya, H.4    Kageyama, S.5    Fridland, A.6    Broder, S.7    Johns, D.G.8
  • 12
    • 0020550770 scopus 로고
    • Conversion of 2-ß-D-ribofuranosyl-selenazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase inhibitory properties
    • Jayaram HN, Ahluwalia GS, Dion RL, Gebeyehu G, Marquez VE, Kelley JA, Robins RK: Conversion of 2-ß-D-ribofuranosyl-selenazole-4-carboxamide to an analogue of NAD with potent IMP dehydrogenase inhibitory properties. Biochem Pharmacol 32: 2633-2636, 1983.
    • (1983) Biochem Pharmacol , vol.32 , pp. 2633-2636
    • Jayaram, H.N.1    Ahluwalia, G.S.2    Dion, R.L.3    Gebeyehu, G.4    Marquez, V.E.5    Kelley, J.A.6    Robins, R.K.7
  • 13
    • 15444343528 scopus 로고    scopus 로고
    • Pyrazole-related derivatives endowed with antitumor and antiviral activities, proced-ures for their preparation, pharmaceutical formulations containing them and intermediates of this process. Patent Appln N PCT/EP96/02485, 1996
    • La Colla P, Manfredini S, Simoni D, Baraldi PG, Pani A: Pyrazole-related derivatives endowed with antitumor and antiviral activities, proced-ures for their preparation, pharmaceutical formulations containing them and intermediates of this process. Patent Appln N PCT/EP96/02485, 1996.
    • La Colla, P.1    Manfredini, S.2    Simoni, D.3    Baraldi, P.G.4    Pani, A.5
  • 14
    • 0026550162 scopus 로고
    • On the modulation of of 6-mercaptopurine by methotrexate in murine WEI-3b leukemia cells in vitro
    • Liliemark J, Pettersson B and Peterson C: On the modulation of of 6-mercaptopurine by methotrexate in murine WEI-3b leukemia cells in vitro. Leukemia Res 16: 275-280, 1992.
    • (1992) Leukemia Res , vol.16 , pp. 275-280
    • Liliemark, J.1    Pettersson, B.2    Peterson, C.3
  • 15
    • 0021368687 scopus 로고
    • Modulation of IMP dehydrogenase activity and guanylate metabolism by tiazofurin (2-ß-D-ribofuranosyl-thiazole-4-carboxamide)
    • Lui MS, Faderan MA, Liepnieks JJ, Natsumeda Y, Olah E, Jayaram HN: Modulation of IMP dehydrogenase activity and guanylate metabolism by tiazofurin (2-ß-D-ribofuranosyl-thiazole-4-carboxamide). J Biol Chem 259: 5078-82, 1984.
    • (1984) J Biol Chem , vol.259 , pp. 5078-5082
    • Lui, M.S.1    Faderan, M.A.2    Liepnieks, J.J.3    Natsumeda, Y.4    Olah, E.5    Jayaram, H.N.6
  • 16
    • 0026546505 scopus 로고
    • Pyrazole- related nucleosides. Synthesis and antiviral / antitumor activity of some substituted pyrazole and pyrazolo(4,3-d)-1,2,3-triazin-4-one nucleosides
    • Manfredini S, Bazzanini R, Baraldi PG, Guarneri M, Simoni D, Marongiu ME, Pani A, Tramontano E, La Colla P: Pyrazole-related nucleosides. Synthesis and antiviral / antitumor activity of some substituted pyrazole and pyrazolo(4,3-d)-1,2,3-triazin-4-one nucleosides. J Med Chem 35: 917-924, 1992.
    • (1992) J Med Chem , vol.35 , pp. 917-924
    • Manfredini, S.1    Bazzanini, R.2    Baraldi, P.G.3    Guarneri, M.4    Simoni, D.5    Marongiu, M.E.6    Pani, A.7    Tramontano, E.8    La Colla, P.9
  • 18
    • 0028334595 scopus 로고
    • Cross-resistance to cisplatin in cells resistant to photofrin-mediated photodinamic therapy
    • Moorhead RA, Armstrong SG, Wilson BC, Singh G: Cross-resistance to cisplatin in cells resistant to photofrin-mediated photodinamic therapy. Cancer Res 54: 2556-2559, 1994.
    • (1994) Cancer Res , vol.54 , pp. 2556-2559
    • Moorhead, R.A.1    Armstrong, S.G.2    Wilson, B.C.3    Singh, G.4
  • 19
    • 0023913956 scopus 로고
    • Synergistic cytotoxic effect of tiazofurin and ribavirin in hepatoma cells
    • Natsumeda Y, Yamada Y, Yamaji Y, Weber G: Synergistic cytotoxic effect of tiazofurin and ribavirin in hepatoma cells. Biochem Biophys Res Commun 153: 321-327, 1988.
    • (1988) Biochem Biophys Res Commun , vol.153 , pp. 321-327
    • Natsumeda, Y.1    Yamada, Y.2    Yamaji, Y.3    Weber, G.4
  • 20
    • 0025828251 scopus 로고
    • Multidrug resistance (mdr) genes in human cancer
    • Nooter K, Herweijer H: Multidrug resistance (mdr) genes in human cancer. Br J Cancer 63: 663-669, 1991 .
    • (1991) Br J Cancer , vol.63 , pp. 663-669
    • Nooter, K.1    Herweijer, H.2
  • 21
    • 15444339681 scopus 로고
    • A pyrazole-related nucleoside with potent and selective antitumor activity, in vitro
    • Personal communication, Toronto, Canada
    • Pani A, Manfredini S, Pinna E, Scintu F, Pisano L, Lichino D, La Colla P: A pyrazole-related nucleoside with potent and selective antitumor activity, in vitro. Personal communication, AACR Meeting, Toronto, Canada, 1995.
    • (1995) AACR Meeting
    • Pani, A.1    Manfredini, S.2    Pinna, E.3    Scintu, F.4    Pisano, L.5    Lichino, D.6    La Colla, P.7
  • 23
    • 0030155862 scopus 로고    scopus 로고
    • Prevention and treatment of hepatitis C
    • Poupon R, Sefarty L: Prevention and treatment of hepatitis C. Bull Acad Natl Med 180: 1279-1289, 1996.
    • (1996) Bull Acad Natl Med , vol.180 , pp. 1279-1289
    • Poupon, R.1    Sefarty, L.2
  • 25
    • 0022575008 scopus 로고
    • Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL-60 leukemia cells produced by inhibitors of inosine 5'-phosphate dehydrogenase
    • A
    • Sokoloski J: A, Blair OC, Sartorelli AC: Alterations in glycoprotein synthesis and guanosine triphosphate levels associated with the differentiation of HL-60 leukemia cells produced by inhibitors of inosine 5'-phosphate dehydrogenase. Cancer Res 46: 2314-2319, 1986.
    • (1986) Cancer Res , vol.46 , pp. 2314-2319
    • Sokoloski, J.A.1    Blair, O.C.2    Sartorelli, A.C.3
  • 26
    • 0020663388 scopus 로고
    • Synthesis and antitumor activity of 2- ß-D-ribofuranosyl-selenazole-4-carboxamide and related derivatives
    • Srivastava PC, Robins RK: Synthesis and antitumor activity of 2-ß-D-ribofuranosyl-selenazole-4-carboxamide and related derivatives. J Med Chem 26: 445-451, 1983.
    • (1983) J Med Chem , vol.26 , pp. 445-451
    • Srivastava, P.C.1    Robins, R.K.2
  • 28
    • 0025189358 scopus 로고
    • Evaluation of synergism or antagonism for the combined actionofantiviralagents
    • 30
    • Suhnel J: Evaluation of synergism or antagonism for the combined actionofantiviralagents. Antiviral Res. 13: 23-40, 1990. 30
    • (1990) Antiviral Res. , vol.13 , pp. 23-40
    • Suhnel, J.1
  • 29
    • 0025340992 scopus 로고
    • Tiazofurin. Biological effects and clinical uses
    • Tricot G, Jayaram HN, Weber G: Tiazofurin. Biological effects and clinical uses. Int J Cell Cloning 8: 161-170, 1990.
    • (1990) Int J Cell Cloning , vol.8 , pp. 161-170
    • Tricot, G.1    Jayaram, H.N.2    Weber, G.3
  • 31
    • 0020955571 scopus 로고
    • Biochemical strategy of cancer cells and the design of chemotherapy. GHA Clowes Memorial Lecture
    • Weber G: Biochemical strategy of cancer cells and the design of chemotherapy. GHA Clowes Memorial Lecture. Cancer Res 43: 3466-3492, 1983.
    • (1983) Cancer Res , vol.43 , pp. 3466-3492
    • Weber, G.1
  • 32
    • 0026346104 scopus 로고
    • IMP dehydrogenase and GTP as targets in human leukemia treatment
    • Harkness RA, editor New York: Plenum Press
    • Weber G: IMP dehydrogenase and GTP as targets in human leukemia treatment. In: Harkness RA, editor. Purine and pyrimidine metabolism in man. VII. Part B. New York: Plenum Press, pp 287-292, 1991.
    • (1991) Purine and Pyrimidine Metabolism in Man , vol.7 , Issue.PART B , pp. 287-292
    • Weber, G.1
  • 33
    • 0028323354 scopus 로고
    • Role of differentiation induction in action of purine antimetabolites
    • Weber G, Hata Y, And Prajda N: Role of differentiation induction in action of purine antimetabolites. Pharmacy World and Sci 16: 77-83, 1994.
    • (1994) Pharmacy World and Sci , vol.16 , pp. 77-83
    • Weber, G.1    Hata, Y.2    Prajda, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.