Experimental destruction of substantia nigra initiated by Parkinson disease immunoglobulins

Archives of Neurology

Volumn 55, Issue 8, 1998, Pages 1075-1080

  Chen, Shengdi ^a,b   Le, Weidong D ^a   Xie, Wenjie J ^a   Alexianu, Maria E ^a   Engelhardt, Joseph I ^a,c   Siklós, Laszlo ^a,c   Appel, Stanley H ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c UNIVERSITY OF SZEGED   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

AGAROSE; CHOLINE ACETYLTRANSFERASE; FREE RADICAL; IMMUNOGLOBULIN G; PROTEIN A; TYROSINE 3 MONOOXYGENASE;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN MEMBRANE; BRAIN REGION; CELL DESTRUCTION; CELL INFILTRATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNE MEDIATED INJURY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MESENCEPHALON; MICROGLIA; NERVE CELL LESION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; SUBSTANTIA NIGRA;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMMUNOGLOBULIN G; PARKINSON DISEASE; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA; TIME FACTORS;

EID: 0031868110     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.55.8.1075     Document Type: Article

References (32)

1. Perry TL, Yong VW. Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients. Neurosci Lett. 1986;67:269-274.
2. Sofic E, Lange KW, Jellinger K, Riederer P. Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease. Neurosci Lett. 1992; 142:128-130.
3. Dexter DT, Carayon A, Javoy-Agid F, et al. Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia. Brain. 1991;114:1953-1975.
4. Mizuno Y, Ohta S, Tanaka M, et al. Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease. Biochem Biophys Res Commun. 1989;163: 1450-1455.
5. Schapira AH, Cooper JM, Dexter D, Clark JB, Jenner P, Marsden CD. Mitochondrial complex I deficiency in Parkinson's disease. J Neurochem. 1990;54: 823-827.
6. Dexter DT, Holley AE, Flitter WD, et al. Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: an HPLC and ESR study. Mov Disord. 1994;9: 92-97.
7. Jenner P, Schapira AH, Marsden CD. New insights into the cause of Parkinson's disease. Neurology. 1992;42:2241-2250.
8. Dexter DT, Sian J, Rose S, et al. Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease. Ann Neurol. 1994;35:38-44.
9. Langston JW, Ballard P, Tetrud JW, Irwin I. Chronic parkinsonism in humans due to a product of meperidine-analog synthesis. Science. 1983;219:979-980.
10. Singer TP, Castagnoli N Jr, Ramsay RR, Trevor AJ. Biochemical events in the development of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Neurochem. 1987;49:1-8.
11. McNaught KS, Thull U, Carrupt PA, et al. Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Biochem Pharmacol. 1995;50:1903-1911.
12. McGeer PL, Itagaki S, Akiyama H, McGeer EG. Rate of cell death in parkinsonism indicates active neuropathological process. Ann Neurol. 1988;24:574-576.
13. McRae-Degueurce A, Rosengren L, Haglid K, et al. Immunocytochemical investigations on the presence of neuron-specific antibodies in the CSF of Parkinson's disease cases. Neurochem Res. 1988;13:679-684.
14. Hao R, Norgren RB Jr, Lau YS, Pfeiffer RF. Cerebrospinal fluid of Parkinson's disease patients inhibits the growth and function of dopaminergic neurons in culture. Neurology. 1995;45:138-142.
15. Appel SH, Le WD, Tajti J, Haverkamp LJ, Engelhardt JI. Nigral damage and dopaminergic hypofunction in mesencephalon-immunized guinea pigs. Ann Neurol. 1992;32:494-501.
16. Le WD, Engelhardt J, Xie WJ, Schneider L, Smith RG, Appel SH. Experimental autoimmune nigral damage in guinea pigs. J Neuroimmunol. 1995;57:45-53.
17. Smith RG, Hamilton S, Hofmann F, et al. Serum antibodies to skeletal muscle-derived L-type calcium channels in patients with amyotrophic lateral sclerosis. N Engl J Med. 1992;327:1721-1728.
18. Paxinos G, Watson C. The Rat Brain in Stereotaxic Coordinates. 2nd ed. Orlando, Fla: Academic Press Inc; 1986.
19. Langston JW, Forno LS, Rebert CS, Irwin I. Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey. Brain Res. 1984;292:390-394.
20. Carman LS, Gage FH, Shults CW. Partial lesion of the substantia nigra: relation between extent of lesion and rotational behavior. Brain Res. 1991;553:275-283.
21. Pakkenberg B, Möller A, Gundersen HJG, Dam AM, Pakkenberg H. The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method. J Neurol Neurosurg Psychiatry. 1991;54:30-33.
22. Ma SY, Collan Y, Röyttä M, Rinne JO, Rinne UK. Cell counts in the substantia nigra: a comparison of single section counts and dissector counts in patients with Parkinson's disease and in controls. Neuropathol Appl Neurobiol. 1995;21:10-17.
23. Lawson LJ, Perry VH, Dri P, Gordon S. Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience. 1990;39:151-170.
24. Thery C, Chamak B, Mallat M. Cytotoxic effect of brain macrophages on developing neurons. Eur J Neurosci. 1991;3:1155-1164.
25. Toyka KV, Drachman DB, Pestronk A, Kao I. Myasthenia gravis: passive transfer from man to mouse. Science. 1975;190:397-399.
26. Wiedan-Pazos M, Goto JJ, Rabizadeh S, et al. Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis. Science. 1996;271:515-518.
27. Smith MA, Sayre LM, Monnier VM, Perry G. Radical ageing in Alzheimer's disease. Trends Neurosci. 1995;18:172-176.
28. Alexianu ME, Ho B-K, Mohammed AH, La Bella V, Smith RG, Appel SH. The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis. Ann Neurol. 1994;36:846-858.
29. 28K. Brain Res. 1990;526:303-307.
30. Nicotera P, Orrenius S. Calcium ions in necrotic and apoptotic cell death. In: Olanow CW, Jenner P, Youdin M, eds. Neurodegeneration and Neuroprotection in Parkinson's Disease. Orlando, Fla: Academic Press Inc; 1996:143-158.
31. Mogi M, Harada M, Riederer P, et al. Tumor necrosis factor-α (TNF-α) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients. Neurosci Lett. 1994;165:208-210.
32. Giulian D, Haverkamp LJ, Li J, et al. Senile plaques stimulate microglia to release a neurotoxin found in Alzheimer brains. Neurochem Int. 1995;27:119-137.