Isolation and structural characterization of five oligosaccharide α1-phosphates and one sulfated glycopeptide from hemofiltrate

Biological Chemistry

Volumn 379, Issue 6, 1998, Pages 737-741

  Iwanowitsch, Andreas ^a   Friebolin, Horst ^a   Carganico, Reinhard ^a   Errenst, Martin ^a   Weißhaar, Gerhard ^a   Brunner, Helmut ^b,c   Mann, Helmut ^b  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c Priv Doz Dr Dr Lembke u Partner   (Germany)

Author keywords

Hemofiltrate; NMR spectroscopy; Oligosaccharides; Phosphates; Sulfates; Uremia

Indexed keywords

GLYCOPEPTIDE; OLIGOSACCHARIDE; PHOSPHATE;

ARTICLE; BLOOD ANALYSIS; CARBOHYDRATE ANALYSIS; CASE REPORT; CHEMICAL STRUCTURE; GEL PERMEATION CHROMATOGRAPHY; HEMOFILTRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ION EXCHANGE CHROMATOGRAPHY; KIDNEY FAILURE; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSE OSMOSIS;

FEMALE; GLYCOPEPTIDES; HUMANS; KIDNEY FAILURE, CHRONIC; MAGNETIC RESONANCE SPECTROSCOPY; OLIGOSACCHARIDES; PHOSPHATES; UREMIA;

EID: 0031867623     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Bergström, J., and Fürst, P. (1983). Uraemic toxins. In: Replacement of Renal Function by Dialysis, 2nd ed. W. Drukker, F.M. Parsons and J.F. Maher, eds. (Boston, USA: Martinus Nijhoff Publishers), pp. 354-390.
2. Brunner, H., and Mann, H. (1982). "Mittelmoleküle" als Urämietoxine. In: Klinische Nephrologie, Vol. I. H. Losse and E. Renner, eds. (Stuttgart, New York: Thieme Verlag), pp. 489-500.
3. Brunner, H., and Mann, H. (1985). What remains of the "middle molecule" hypothesis today? Contr. Nephrol. 44, 14-39.
4. Brunner, H., Weißhaar, G., Friebolin, H., Mann, H., Baumann, W., Sieberth, H.-G. (1989). Isolation and identification of sialylcompounds from hemofiltrate. Chromatographia 28, 59-64.
5. Capon, C., Leroy, Y., Wieruszeski, J.-M., Ricart, G., Strecker, G., Montreuil, J., and Fournet, B. (1989). Structures of O-glycosidically linked oligosaccharides isolated from human meconium glycoproteins. Eur. J. Biochem. 182, 139-152.
6. Carganico, R. (1992). Isolierung und Strukturaufklärung von sauren Oligosacchariden aus dem Hämofiltrat. Universität Heidelberg, Dissertation.
7. Derappe, C., Bauvy, C., Lemonnier, M., Lhermitte, M., Platzer, N., Egge, H., Peter-Kalinic, J., van Halbeek, H., Kamerling, J.P., and Vliegenthart, J.F.G. (1986). Determination of the structure of a fucose-containing trisaccharide monophosphate isolated from human pregnancy urine. Carbohydr. Res. 150, 273-284.
8. Dorland, L., Schut, B.L., Vliegenthart, J.F.G., Strecker, G., Fournet, B., Spik, G., and Montreuil, J. (1977). Structural studies on 2-acetamido-1-N-(4-L-aspartyl)-2-deoxy-β-D-glucopyranosylamine and 2-acetamido-6-O-(-L-fucopyranosyl)-1-N-(4-L-aspartyl)-2-deoxy-β-D- glucopyranosylamine by 360-MHz proton-magnetic-resonance spectroscopy. Eur. J. Biochem. 73, 93-97.
9. Dua, V.K., and Bush, C.A. (1983). Identification and fractionation of human milk oligosaccharides by proton-nuclear magnetic resonance spectroscopy and reverse-phase high-performance liquid chromatography. Anal. Biochem. 133, 1-8.
10. Errenst, M. (1990). Isolierung von sauren Kohlenhydraten aus Hämofiltrat und ihre Identifizierung durch Kernresonanzspektroskopie. Universität Heidelberg, Dissertation.
11. Hindsgaul, V., Hindsgaul, O., and Baenziger, J.U. (1987). Synthesis of oligosaccharide structures unique to pituitary glycoprotein hormones. Can. J. Chem. 65, 1645.
12. Iwanowitsch, A. (1992). Isolierung und Charakterisierung saurer Oligosaccharide aus dem Hämofiltrat. Universität Heidelberg, Diplomarbeit.
13. Parkkinen, J., and Finne, J. (1987). Isolation of sialyl oligosaccharides and sialyl oligosaccharide phosphates from bovine colostrum and human urine. Methods in Enzymology 138, 289-300.
14. 1H-NMR spectroscopy. Eur. J. Biochem. 182, 457-476.
15. Quellhorst, E. (1982). Hämodiafiltration, Ultrafiltration, sequentielle Ultrafiltration/Dialyse, Hämofiltration. In: Klinische Nephrologie. H. Losse and E. Renner, eds. (Stuttgart, New York: Thieme Verlag), pp. 559-565.
16. Sarre, H., Gessler, U., and Seybold, D. (1988). Nierenkrankheiten, Physiologie, Pathophysiologie. (Stuttgart, New York: Thieme Verlag), pp. 206-245.
17. Strecker, G., Wieruszeski, J.-M., Michalski, J.-C., and Montreuil, J. (1990). Isolation and characterisation of three fucosyloligosaccharide-1-phosphates from normal human urine. Glycoconjugate J. 7, 235-245.
18. 1H-NMR spectroscopy. Eur. J. Biochem. 127, 7-20.
19. Vanholder, R., Schoots, A., and Ringoir, S. (1989). Uremic toxicity. In: Replacement of Renal Function by Dialysis, 3rd ed. J.F. Maher, ed. (Dordrecht, The Netherlands: Kluwer Academic Publishers), pp. 4-19.
20. Weißhaar, G., Baumann, W., Friebolin, H., Brunner, H., Mann, H., Sieberth, H.-G., and Opferkuch, H.-J. (1987a). Isolierung und NMR-spektroskopische Charakterisierung sialinsäurehaltiger Verbindungen aus dem Hämofiltrat chronisch urämischer Patienten. Biol. Chem. Hoppe-Seyler 368, 647-658.
21. Weißhaar, G., Baumann, W., Friebolin, H., Brunner, H., Mann, H., Sieberth, H.-G., and Opferkuch, H.-J. (1987b). Sialinsäurehaltige Verbindungen im Hämofiltrat von Patienten mit chronischer Niereninsuffizienz, II. Isolierung und Strukturaufklärung von Sialoglycopeptiden. Biol. Chem. Hoppe-Seyler 368, 1545-1558.