Protein kinase A-mediated inhibition of gamma interferon-induced tyrosine phosphorylation of Janus kinases and latent cytoplasmic transcription factors in human monocytes by Ehrlichia chaffeensis

Infection and Immunity

Volumn 66, Issue 6, 1998, Pages 2514-2520

  Lee, Eunjoo H ^a   Rikihisa, Yasuko ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DANSYLCADAVERINE; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; PERIODATE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE; PROTEINASE K; RECOMBINANT GAMMA INTERFERON; STAT1 PROTEIN; TRANSCRIPTION FACTOR; TYROSINE;

ARTICLE; CONTROLLED STUDY; EHRLICHIA CHAFFEENSIS; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 0031867451     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.6.2514-2520.1998     Document Type: Article

References (38)

1. Andersen, B. E., J. E. Dawson, D. C. Jones, and K. E. Wilson. 1991. Ehrlichia chaffeensis, a new species associated with human ehrlichiosis. J. Clin. Microbiol. 29:2838-2842.
2. Anderson, B. E., K. G. Sims, J. G. Olson, J. E. Childs, J. F. Piesman, C. M. Happ, G. O. Maupin, and B. J. B. Johnson. 1993. Amblyomma americanum: a potential vector of human ehrlichiosis. Am. J. Trop. Med. Hyg. 49:239-244.
3. Barnewall, R. E., and Y. Rikihisa. 1994. Abrogation of gamma interferoninduced inhibition of Ehrlichia chaffeensis infection in human monocytes with iron transferrin. Infect. Immun. 62:4804-4810.
4. Barnewall, R. E., Y. Rikihisa, and E. H. Lee. 1997. Ehrlichia chaffeensis inclusions are early endosomes which selectively accumulate transferrin receptor. Infect. Immun. 65:1455-1461.
5. Bhardwaj, N., T. W. Nash, and M. A. Horwitz. 1986. Interferon-γ-activated human monocytes inhibit the intracellular multiplication of Legionella pneumophila. J. Immunol. 137:2662-2669.
6. Briscoe, J., F. Kohlhuber, and M. Muller. 1996. JAKs and STATs branch out. Trends Cell Biol. 6:336-340.
7. Buchmeier, N. A., and R. D, Schreiber. 1985. Requirement of endogenous interferon-γ production for resolution of Listeria monocytogenes infection. Proc. Natl. Acad. Sci. USA 82:7404-7408.
8. Darnell, J. E., Jr., I. M. Kerr, and G. R. Stark. 1994. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 264:1415-1421.
9. David, M., H. E. Chen, S. Goelz, A. C. Larner, and B. G. Neel. 1995. Differential regulation of the alpha/beta interferon-stimulated Jak/Stat pathway by the SH2 domain-containing tyrosine phosphatase SHPTP1. Mol. Cell. Biol. 15:7050-7058.
10. David, M., E. Petricoin III, and A. C. Larner. 1996. Activation of protein kinase A inhibits interferon induction of the Jak/Stat pathway in U266 cells. J. Biol. Chem. 271:4585-4588.
11. Dawson, J. E., B. E. Anderson, D. B. Fishbein, J. L. Sanchez, C. S. Goldsmith, K. H. Wilson, and C. W. Duntley. 1991. Isolation and characterization of an Ehrlichia sp. from a patient diagnosed with human ehrlichiosis. J. Clin. Microbiol. 29:2741-2745.
12. Dumler, J. S., and J. S. Bakken. 1995. Ehrlichial diseases of humans: emerging tick-borne infections. Clin. Infect. Dis. 20:1102-1110.
13. Farrar, M. A., and R. D. Schreiber. 1993. The molecular cell biology of interferon-γ and its receptor. Annu. Rev. Immunol. 11:571-611.
14. Green, S. J., R. M. Crawford, J. T. Hockmeyer, M. S. Meltzer, and C. A. Nacy. 1990. Leishmania major amastigotes initiate the L-arginine-dependent killing mechanism in IFN-γ-stimulated macrophages by induction of tumor necrosis factor-α. J. Immunol. 145:4290-4297.
15. Ivashkiv, L. B., E. M. Schmitt, and A. Castro. 1996. Inhibition of transcription factor Stat1 activity in mononuclear cell cultures and T cells by the cyclic AMP signaling pathway. J. Immunol. 157:1415-1421.
16. Klingmuller, U., U. Lorenz, L. C. Cantley, B. G. Neel, and H. F. Lodish. 1995. Specific recruitment of SH-PTP1 to the erythropoietin receptor causes in-activation of JAK2 and termination of proliferative signals. Cell 80:729-738.
17. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685.
18. Lee, E. H., and Y. Rikihisa. 1996. Absence of tumor necrosis factor alpha, interleukin-6 (IL-6), and granulocyte-macrophage colony-stimulating factor expression but presence of IL-1β, IL-8, and IL-10 expression in human monocytes exposed to viable or killed Ehrlichia chaffeensis. Infect. Immun. 64:4211-4219.
19. Lee, E. H., and Y. Rikihisa. 1997. Anti-Ehrlichia chaffeensis antibody induces potent proinflammatory cytokinc mRNA expression in human monocytes exposed to E. chaffeensis through sustained reduction of IκB-α and activation of NF-κB. Infect. Immun. 65:2898-2903.
20. 1 cells by Ehrlichia risticii infection in response to gamma Interferon. Vet. Immunol. Immunopathol. 32:225-241.
21. Messick, J. B., and Y. Rikihisa. 1993. Characterization of Ehrlichia risticii binding, internalization, and proliferation in host cells by flow cytometry. Infect. Immun. 61:3803-3810.
22. 1 cells by anti-E. risticii serum, immunoglobulin G1 or Fab fragment. Infect. Immun. 62:3156-3161.
23. Nandan, D., and N. E. Reiner. 1995. Attenuation of gamma interferon-induced tyrosine phosphorylation in mononuclear phagocytes infected with Leishmania donovani: selective inhibition of signaling through Janus kinases and Stat 1. Infect. Immun. 63:4495-4500.
24. Park, J., and Y. Rikihisa. 1992. L-Arginine-dependent killing of intracellular Ehrlichia risticii by macrophages treated with gamma Interferon. Infect. Immun. 60:3504-3508.
25. Ohashi, N., N. Zhi, Y. Zhang, and Y. Rikihisa. 1998. Immunodominant major outer membrane proteins of Ehrlichia chaffeensis are encoded by a polymorphic multigene family. Infect. Immun. 66:132-139.
26. Reithmann, C., P. Gierschik, and K. H. Jakobs. 1990. Stimulation and inhibition of adenylyl cyclase. Symp. Soc. Exp. Bioi. 44:207-224.
27. Rikihisa, Y. 1991. The tribe Ehrlichieae and ehrlichial diseases. Clin. Microbiol. Rev. 4:286-308.
28. Rikihisa, Y., G. C. Johnson, Y. Wang, S. M. Reed, R. Fertel, H. J. Cooke. 1992. Loss of absorptive capacity for sodium and chloride in the colon causes diarrhoea in Potomac horse fever. Res. Vet. Sci. 52:353-362.
29. Rothermel, J. D., and L. H. P. Botelho. 1988. A mechanistic and kinetic analysis of the interactions of the diastereoisomers of adenosine 3′,5′-(cyclic)phosphorothioate with purified cyclic AMP-dependent protein kinase. Biochem. J. 251:757-762.
30. Shuai, K., C. Schindler, V. R. Prezioso, and J. E. Darnell, Jr. 1992. Activation of transcription by IFN-γ: tyrosine phosphorylation of a 91-kD DNA binding protein. Science 258:1808-1812.
31. Suzuki, Y., M. A. Orellana, R. D. Schreiber, and J. S. Remington. 1988. Interferon-γ: the major mediator of resistance against Toxoplasma gondii. Science 240:516-518.
32. Tsuchiya, S., M. Yamake, Y. Yamaguchi, Y. Kobayashi, T. Konno, and K. Tada. 1980. Establishment and characterization of human monocytic leukemia ceil line (THP-1). Int. J. Cancer 26:171-176.
33. Tsuchiya, S., Y. Kobayashi, Y. Goto, H. Okumura, S. Nakae, T. Konno, and K. Tada. 1992. Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester. Cancer Res. 42:1530-1536.
34. 2 production in murine peritoneal macrophages infected with Ehrlichia risticii. Infect. Immun. 61:4333-4337.
35. Woodward, M. P., W. W. Young, Jr., and R. A. Bloodgood. 1985. Detection of monoclonal antibodies specific for carbohydrate epitopes using periodate oxidation. J. Immunol. Methods 78:143-153.
36. Yetter, A., S. Uddin, J. J. Krolewski, H. Jiao, T. Yi, and L. C. Platanias. 1995. Association of the interferon-dependent tyrosine kinase Tyk-2 with the hematopoietic cell phosphatase. J. Biol. Chem. 270:18179-18182.
37. Yi, T., A. L.-F. Mui, G. Krystal, and J. N. Ihle. 1993. Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor β chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis. Mol. Cell. Biol. 13:7577-7586.
38. Yokozaki, H., G. Tortora, S. Pepe, E. Maronde, H.-G. Genieser, B. Jastorff, and Y. S. Cho-Chung. 1992. Unhydrolyzable analogues of adenosine 3′:5′-monophosphate demonstrating growth inhibition and differentiation in human cancer cells. Cancer Res. 52:2504-2508.