Orally administered lactobacillus strains differentially affect the direction and efficacy of the immune response

Veterinary Quarterly

Volumn 20, Issue , 1998, Pages 81-83

  Maassen, C B M ^a   van Holten, J C A M ^a   Balk, F ^a   den Bak Glashouwer, M J Heijne ^a   Laman, J D ^a   Leer, R ^a   Boersma, W J A ^b   Claassen, E ^c  

^a TNO   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

LACTOBACILLUS VACCINE;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; CONFERENCE PAPER; CYTOKINE PRODUCTION; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; LACTOBACILLUS; NONHUMAN; RAT;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, ORAL; ANIMALS; ANTIBODY FORMATION; CYTOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; GAMMA-GLOBULINS; INTESTINE, SMALL; LACTOBACILLUS; MICE; MICE, INBRED BALB C; PICRATES; PROBIOTICS;

EID: 0031867239     PISSN: 01652176     EISSN: 18755941     Source Type: Journal    
DOI: 10.1080/01652176.1998.9694976     Document Type: Article

References (6)

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2. Boersma WJA, Zegers ND, Bogaerdt A van den, Leer RJ, Bergmans A, Pouwels PH, Posno M, and Claassen E. Development of safe oral vaccines based on Lactobacillus as a vector with adjuvant activity. Proc. ICHEM 2nd. Intematl. Congr. Biotech UK, Brighton: Industrial Immunology 1994: 43–6.
3. Gerritse K, Posno M, Schellekens MM, Boersma WJA, and Claassen E. Oral administration of TNP-Lactobacillus conjugates in mice: A model for evaluation of mucosal- and systemic immune responses and memory formation elicited by transformed lactobacilli. Res Microbiol 1990; 141: 955–62.
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6. Maassen CBM, Gerritse K, Leer RJ, Heemskerk D, Boersma WJA, and Claassen E. Lactobacillus as a vector for oral delivery of antigens; the role of intrinsic adjuvanticity in modulation of the immune response. Proc. 9th Int. Congress Mucosal Immunology, Sydney Australia. 1997 (in press).