Fibrinolytic action on fresh human clots of whole body extracts and two semipurified fractions from Lonomia achelous caterpillar

Brazilian Journal of Medical and Biological Research

Volumn 31, Issue 6, 1998, Pages 779-784

  Coll Sangrona, E ^a   Arocha Pinango C L ^a  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

Author keywords

Clot lysis; Fibrinolysis; Lonomia achelous caterpillars; Plasmin

Indexed keywords

ALPHA 2 ANTIPLASMIN; ALPHA 2 MACROGLOBULIN; FIBRIN; FIBRINOGEN DEGRADATION PRODUCT; IMIDAZOLE; PLASMIN; PROTEINASE INHIBITOR; TRYPSIN; VENOM;

ARTICLE; BLEEDING TENDENCY; BLOOD CLOT; BLOOD CLOT LYSIS; EXTRACT; FIBRINOLYSIS; HUMAN; LARVA; LEPIDOPTERA;

EID: 0031866931     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X1998000600009     Document Type: Article

References (22)

1. Arocha-Pin̄ango CL (1967). Fibrinolisis producida por contacto con orugas Comunicación preliminar. Acta Científica Venezolana, 18: 136-139.
2. Arocha-Pin̄ango CL & Layrisse M (1969). Fibrinolysis produced by contact with a caterpillar. Lancet 19: 810-812.
3. Arocha-Pin̄ango CL, Bosch NB de, Nouel A, Torres A, Perales J, Alonso M, Rodriguez S, Carvajal Z, Ojeda A, Tasayco ML & Chitty W (1988). Fibrinolytic and procoagulant agents from a Saturniidae moth caterpillar. In: Pirkle H & Markland FDS (Editors), Hemostasis and Animal Venoms. Marcel Decker Inc., New York, 223-240
4. Arocha-Pin̄ango CL, Bosch NB, Torres A, Goldstain C, Nouel A, Argüello A, Carvajal Z, Guerrero B, Ojeda A, Rodriguez A & Rodríguez S (1992). Six new cases of a caterpillar induced bleeding syndrome. Thrombosis and Haemostasis, 67: 402-407.
5. Arocha-Piñango CL, Marsh NA & Robinson D (1973). A fibrinolytic agent from a Saturniidae caterpillar. Partial purification and characterization. Thrombosis et Diathesis Haemorrhagica, 29: 135-142.
6. Arocha-Pin̄ango CL, Perales J & Carvajal Z (1981). Studies on the degradation of fibrinogen by proteolytic enzymes from the larvae of Lonomia achelous (Cramer). Thrombosis and Haemostasis, 45: 233-236.
7. Lowry OH, Rosebrough NJ, Farr AL & Randall RS (1951). Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry, 193: 265-275.
8. Astrup T & Müllertz S (1952). Fibrin plate method for estimating fibrinolytic activity. Archives of Biochemistry and Biophysics, 40: 346-451
9. Marsh NA & Arocha-Pin̄ango CL (1972). Evaluation of the fibrin plate method for estimating plasminogen activators. Thrombosis et Diathesis Haemorrhagica, 28: 75-88.
10. Arocha-Pin̄ango CL & Pepper DS (1981). Studies of a fibrinolytic enzyme from the larvae of Lonomia achelous (Cramer) using chromogenic peptide substrates. Thrombosis and Haemostasis, 46: 710-713.
11. Sabovic M, Lijnen HR, Keber D & Collen D (1989). Effect of retraction on the lysis of human clots with fibrin specific and non specific plasminogen activator. Thrombosis and Haemostasis, 62: 1083-1987.
12. Van Assendelft OW, Holtz AH & Lewis SM (1984). Recommended Method for the Determination of the Haemoglobin Content of Blood. I.C.S.H. Publications, World Health Organization, 1.4.1.
13. Spiegel MR (1978). Estadistica Teoria y Problemas. McGraw-Hill, New York.
14. Gurewich V & Pannell R (1986). A comparative study of the efficacy and specificity of tissue plasminogen activator and pro-urokinase; demonstration of synergism and of different thresholds of non-selectivity. Thrombosis Research, 44: 217-228.
15. Matsuo O, Rijken DC & Collen D (1981). Comparison of the relative fibrinogenolytic, fibrinolytic and thrombolytic properties of tissue plasminogen and urokinase in vitro. Thrombosis and Haemostasis, 43: 225-229.
16. Matsuo O, Rijken DC & Collen D (1981). Thrombolysis by human tissue plasminogen activator and urokinase in rabbits with experimental pulmonary embolus. Nature, 291: 590-591.
17. Pannell R & Gurewich V (1986). Pro-urokinase: A study of stability in plasma of a mechanism for its selective fibrinolytic effect. Blood, 67: 1215-1223.
18. Takada A, Takada Y & Urano T (1994). The physiological aspects of fibrinolysis. Thrombosis Research, 76: 1-3.
19. Aznar J, Estelles A & Gilabert J (1994). Fibrinolytic Inhibitors. Cellular, Biological and Clinical Aspects. Editorial Garsi S.A., Madrid, Spain.
20. Binder BR (1995). Physiology and pathophysiology of the fibrinolytic system. Fibrinolysis, 9 (Suppl 1): 3-8.
21. Bachman F (1995). Fibrinolytic agents. Fibrinolysis, 9 (Suppl 1): 9-15.
22. Van Meijer M & Pannekoek HL (1995). Structure of plasminogen activator inhibitor 1 (PAI-1) and its function in fibrinolysis: an update. Fibrinolysis, 9: 263-276