The effects of diabetes mellitus on the material properties of human metatarsal bones

Journal of Foot and Ankle Surgery

Volumn 37, Issue 3, 1998, Pages 195-198

  Fleischli, John G ^a   Laughlin, Terese J ^a   Lavery, Lawrence A ^b   Shah, Bhavesh ^c   Lanctot, Dan ^b   Agrawal, C Mauli ^b   Athanasiou, Kyriakos ^b  

^a Hlth Science Center at San Antonio ^*  (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c Dr W M Scholl Coll Podiatric M

Author keywords

Bone; Diabetes mellitus; Elastic modulus; Fracture; Material properties of bone; Metatarsal

Indexed keywords

ADULT; AGED; ARTICLE; BONE STRENGTH; BONE STRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; FOOT AMPUTATION; HISTOLOGY; HUMAN; HUMAN TISSUE; METATARSAL BONE; MOBILIZATION; OUTCOMES RESEARCH;

EID: 0031866805     PISSN: 10672516     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1067-2516(98)80110-5     Document Type: Article

References (31)

1. Cowie, C. C., Eberhardt, M. S., eds Diabetes 1996: Vital Statistics, p. 102. American Diabetes Association, Alexandria, VA, 1996.
2. Levin, M. E., Boisseau, V. C., Avioli, L. V., Effects of diabetes mellitus on bone mass in juvenile and adult-onset diabetes. N. Engl. J. Med. 294:241-245, 1976.
3. Matsumoto, M., Goriya, Y., Sekimoto, H. Osteopenic changes in high sugar diet-induced diabetic rabbits (HSDD-R). Diabetes Res. 18:115-122, 1991.
4. Santiago, J., et al. Decreased cortical thickness and osteopenia in children with diabetes mellitus. J. Clin. Endocrinol. Metab. 45:845-848, 1977.
5. Goodman, W. H., Hori, M. T. Diminished bone formation in experimental diabetes: Relationship to osteoid maturation and mineralization. Diabetes 33:825-831, 1984.
6. Locatto, M. E., et al. Growth and development of bone mass in untreated alloxan diabetic rats. Effects of collagen glycosylation and parathyroid activity on the bone turnover. Bone Mineral. 23:129-144, 1993.
7. McNair, P., Madsbad, S. Bone mineral loss in insulin-treated diabetes mellitus: Studies on pathogenesis. Acta Endocrinolo. 90:463-472, 1979.
8. Levy, J., et al., Abnormal cell calcium concentrations in cultured bone cells obtained from femurs of obese and noninsulin-dependent diabetic rats. Calc. Tiss. Inter. 44:131-137, 1989.
9. Heinze, E., Vetter, U. Skeletal growth of fetuses form Streptozocin diabetic rat mothers: In vivo and in vitro studies. Diabetologia 30:100-103, 1987.
10. Dixit, P. K., Elkstrom, R. A. Decreased breaking strength of diabetic rat bone and its improvement by insulin treatment. Calcif. Tissue Int. 32:195-199, 1980.
11. Macey, L. R., et al., Defects of early fracture-healing in experimental diabetes. J. Bone Joint Surg. 71-A:722-733, 1989.
12. Dixit, P. K., Elkstrom, R. A. Retardation of bone fracture healing in experimental diabetes. Indian J. Med. Res. 85:426-435, 1987.
13. Wray, J. B., Stunkle, E. The effects of experimental diabetes upon the breaking strength of the healing fracture in the rat. J. Surg. Res. 5:479-481, 1965.
14. Herbsman, H., et al. Retardation of fracture healing in experimental diabetes. J. Surg. Res. 8:424-431, 1968.
15. Burstein, A. H., Reilly, D. T., Martens, M. Aging of bone tissue: Mechanical properties. J. Bone Joint Surg. 58-A:82-86, 1976.
16. Courtney, A. C., et al. Age-related reductions in the strength of the femur tested in a fall-loading configuration. J. Bone Joint Surg. 77-A.387-395, 1995.
17. Courtney, A. C., et al. Effects of age, density, and geometry on the bending strength of human metetarsals. Foot Ankle Int. 18:216-221, 1997.
18. Topping, R. E., Bolander, M E., Balian, G., Type X collagen in fracture callus and the effects of experimental diabetes. CORR 308:220-228, 1994.
19. Anacker, S. L., Di Fabio, R. P. Influence of sensory inputs on standing balance in community-dwelling elders with recent history of falling. Phys. Ther. 72:26-32, 1992.
20. Lassila, V., Virtanen, P. Impact of Streptozotocin-induced diabetes on rat Wood and alveolar bone affected by occlusal stress. Scand. J. Dent. Res. 97:216-221, 1989.
21. Verhaeghe, J., et al., Bone and mineral metabolism in BB rats with long-term diabetes: Decreased bone turnover and osteoporosis. Diabetes 39:447-482, 1990.
22. Ziv, I., et al. Physiochemical properties of the aging and diabetic sand rat intervertebral disc. J. Orthop. Res. 10:202-210, 1992.
23. Black, C. T., et al. Protein glycosylation and collagen metabolism in normal and diabetic rats. J. Surg. Res. 47:200-202, 1989.
24. Chang, K., et al. Increased collagen cross-linkages in experimental diabetes. Diabetes 29:778-781, 1980.
25. Schneir, M., Ramamurthy, N., Golub, L. Skin collagen metabolism in the streptozotocin-induced diabetic rat: Enhanced catabolism of collagen formed both before and during the diabetic state. Diabetes 31:426-431, 1982.
26. Spanheimer, R. G. Direct inhibition of collagen production in vitro by diabetic rat serum. Diabetes 37:371-376, 1988.
27. Spanheimer, R. G., Umpierrez, G. E., Stumpf, V. Decreased collagen production in diabetic rats. Diabetes 37:371-376, 1988.
28. Spanheimer, R. G. Collagen production in bone and cartilage after short-term exposure to streptozotocin. Matrix 9:172-174, 1989.
29. Umpierrez, G. E., et al Nutritional and hormonal regulation of articular collagen production in diabetic animals. Diabetes 38:758-763, 1989.
30. Weiss, R. E., Gorn, A. H., Nimmi, M. E. Abnormalities in the biosynthesis of cartilage and bone proteoglycans in experimental diabetics. Metabolism 31:848-854, 1981.
31. Monnier, V. M., Kohn, R., Cerami, A. Accelerated age-related browning of human collagen in diabetes mellitus. Proc. Natl. Acad. Sci. USA 81:583-587, 1984.