Prognostic implications of epidermal growth factor receptor immunoreactivity in squamous cell carcinoma of the oral mucosa

Journal of Pathology

Volumn 185, Issue 2, 1998, Pages 167-174

  Maiorano, Eugenio ^a   Favia, Gianfranco ^b   Maisonneuve, Patrick ^c   Viale, Giuseppe ^d  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

^c EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

Epidermal growth factor receptor; Immunohistochemistry; Neoplasm; Oral mucosa; Squamous cell carcinoma

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR;

ARTICLE; CANCER RECURRENCE; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE COURSE; DISEASE MARKER; FEMALE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MOUTH CARCINOMA; PRIORITY JOURNAL; PROGNOSIS; RECEPTOR DENSITY; RECEPTOR DOWN REGULATION; SQUAMOUS CELL CARCINOMA;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CELL MEMBRANE; DISEASE-FREE SURVIVAL; DOWN-REGULATION; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MIDDLE AGED; MOUTH MUCOSA; MOUTH NEOPLASMS; MULTIVARIATE ANALYSIS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SURVIVAL RATE;

EID: 0031866671     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9896(199806)185:2<167::AID-PATH70>3.0.CO;2-E     Document Type: Article

References (54)

1. Bartow SA. Oncogenes and surgical pathology. Semin Diagn Pathol 1987; 4: 194-199.
2. Willman CL, Fenoglio-Preiser CM. Oncogenes, suppressor genes and carcinogenesis. Hum Pathol 1987; 18: 895-902.
3. Olashaw NE, O'Keefe EJ, Pledger WJ. Platelet-derived growth factor modulates epidermal growth factor receptors by a mechanism distinct from that of phorbol esters. Proc Natl Acad Sci USA 1986; 83: 3834-3839.
4. Massague J. Transforming growth factor beta modulates the high affinity receptors for epidermal growth factor and transforming growth factor alpha. J Cell Biol 1985; 100: 1500-1514.
5. Hunter T, Ling N, Cooper JA. Protein kinase C with phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane. Nature 1984; 311: 480-483.
6. Sherrill JM, Kyte J. Activation of epidermal growth factor receptor by epidermal growth factor. Biochemistry 1996; 35: 5705-5718.
7. Ekstrand AJ, Liu L, He J, et al. Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor. Oncogene 1995; 10: 1455-1460.
8. Basu A, Murthy U, Rodeck U, Herlyn M, Mattes I, Das M. Presence of tumour-associated antigens in epidermal growth factor receptors from different human carcinomas. Cancer Res 1987; 47: 2531-2536.
9. Ozanne B, Richards CS, Hendler F, Burns D, Gusterson B. Over-expression of the EGF receptor is a hall mark of squamous cell carcinomas. J Pathol 1986; 149: 9-14.
10. Yamamoto T, Kamata N, Kawano H. High incidence of amplification of the epidermal growth factor receptor gene in human squamous carcinoma cell lines. Cancer Res 1986; 46: 414-416.
11. Game SM, Stone A, Scully C, Prime SS. Tumour progression in experimental oral carcinogenesis is associated with changes in EGF and TGF-beta receptor expression and altered responses to these growth factors. Carcinogenesis 1990; 11: 965-973.
12. Game SM, Stone A, Matthews JB, Scully C, Prime SS. Differentiation of malignant oral keratinocytes reflects changes in EGF and TGF-beta receptor expression but not growth factor dependence. Carcinogenesis 1991; 12: 409-416.
13. Foekens JA, Van Putten WLJ, Portengen H, et al. Prognostic value of pS2 protein and receptors for epidermal growth factor (EGF-R), insulin-like growth factor-1 (IGF-1-R) and somatostatin (SS-R) in patients with breast and ovarian cancer. J Steroid Biochem Mol Biol 1990; 37: 815-821.
14. Gullick WJ, Harsden JJ, Whittle N, Ward B, Bobrow L, Waterfield MD. Expression of EGF on human cervical ovarian and vulval carcinomas. Cancer Res 1986; 46: 285-292.
15. Hendler FJ, Ozanne BW. Human squamous cell lung cancers express increased epidermal growth factor receptors. J Clin Invest 1984; 74: 647-651.
16. Ishikawa J, Maeda S, Umezu K, Sugiyama T, Kamidono S. Amplification and overexpression of the EGF receptor gene in human renal-cell carcinoma. Int J Cancer 1990; 45: 1018-1021.
17. Korc M. Potential role of the epidermal growth factor receptor in human pancreatic cancer. Int J Pancreatol 1990; 7: 71-81.
18. Gusterson B, Cowley G, McIlhlinney J, Ozanne B, Fisher C, Reeves B. Evidence for increased EGF receptors in human sarcomas. Int J Cancer 1985; 36: 689-693.
19. Nurnberg P, Zischler H, Fuhrmann E, et al. Coamplification of simple repetitive DNA fingerprint fragments and the EGF receptor gene in human gliomas. Genes Chrom Cancer 1991; 3: 79-88.
20. Perosio MP, Brooks JJ. Expression of growth factors and growth factor receptors in soft tissue tumours. Implication for the autocrine hypothesis. Lab Invest 1989; 60: 245-253.
21. Roholl PJM, Weima SM, Prinsen L, De Weger RA, Den Otter W, Van Unnik JAM. Expression of growth factors and their receptors on human sarcomas. Immunohistochemical detection of platelet-derived growth factor, EGF and their receptors. Cancer J 1991; 4: 83-88.
22. Easty DM, Easty GC, Carter RL, Monoghan P, Butler LJ. Ten human carcinoma cell lines derived from squamous carcinomas of the head and neck. Br J Cancer 1981; 43: 772-785.
23. Field JK, Spandidos DA. Expression of oncogenes in human tumours with special reference to the head and neck region. J Oral Pathol 1987; 16: 97-107.
24. Furuta Y, Takasu T, Asai T, et al. Clinical significance of the epidermal growth factor receptor gene in squamous cell carcinomas of the nasal cavities and paranasal sinuses. Cancer 1992; 69: 358-362.
25. Kearsley JH, Leonard JH, Walsh MD, Wnght GR. A comparison of epidermal growth factor receptor (EGFR) and c-erbB-2 oncogene expression in head and neck squamous cell carcinomas. Pathology 1992; 23: 189-194.
26. Sakai H, Kawano K, Okamura K, Hashimoto N. Immunohistochemical localisation of c-myc oncogene product and EGF receptor in oral squamous cell carcinoma. J Oral Pathol Med 1990; 19: 1-4.
27. Partridge M, Gullick WJ, Langdon JD, Sherrif M. Expression of epidermal growth factor receptor on oral squamous cell carcinoma. Br J Oral Maxillofac Surg 1988; 26: 381-389.
28. Shirasuna K, Hayashido Y, Sugiyama M, Yoshioka H, Matsuya T. Immunohistochemical localisation of EGF and EGF receptor in human oral mucosa and its malignancy. Virchows Arch A [Pathol Anat] 1991; 418: 349-353.
29. Van Noorden S. Tissue preparation and immunostaining for light microscopy. In: Polak JM, Van Noorden S, eds. Immunocytochemistry. Modern Methods and Applications. Bristol: Wright, 1986; 26-53.
30. Cox DR. Regression models and life-tables (with discussion). J R Stat Soc. Ser B 1972; 34: 187-220.
31. Marubini E, Valecchi MG. Analysing Survival Data from Clinical Trials and Observations Studies. Chichester: John Wiley, 1995.
32. Kalbfleish JD, Prentice RL. The Statistical Analysis of Failure Time Data. New York: John Wiley, 1980.
33. Snedecor GW, Cochran WG. Statistical Methods. 8th edn. Ames: Iowa State University Press, 1989.
34. Scully C. Oncogenes, tumour suppressor genes and viruses in oral squamous carcinoma. J Oral Pathol Med 1993; 22: 337-347.
35. Brandt B, Vogt U, Schlotter CM, et al. Prognostic relevance of aberrations in the erbB oncogenes from breast, ovarian, oral and lung cancers: double-differential polymerase chain reaction (ddPCR) for clinical diagnosis. Gene 1995; 159: 35-42.
36. Haugen DR, Akslen LA, Varhaug JE, Lillehaug JR. Expression of c-erb-B3 and c-erb-B4 proteins in papillary thyroid carcinomas. Cancer Res 1996; 56: 1184-1188.
37. Bacus SS, Yarden Y, Oren M, et al. Neu differentiation factor (heregulin) activates a p53-dependent pathway in cancer cells. Oncogene 1996; 12: 2535-2547.
38. Alimandi M, Romano A, Curia MC, et al. Cooperative signalling of Erb B3 and Erb B2 in neoplastic transformation and human mammary carcinomas. Oncogene 1995; 10: 1813-1821.
39. Beckmann MW, Niederacher D, Massenkeil G, et al. Expression analysis of epidermal growth factor receptor and HER-2/neu: no advantage of prediction of recurrence or survival in breast cancer patients. Oncology 1996; 53: 441-447.
40. Kristensen GB, Holm R, Abeler VM, Trope CG. Evaluation of the prognostic significance of cathepsin D, epidermal growth factor receptor and c-erb-B2 in early cervical squamous cell carcinoma. An immunohistochemical study. Cancer 1996; 78: 433-440.
41. Kim JW, Kim YT, Kim DK, Song CH, Lee JW. Expression of epidermal growth factor receptor in carcinoma of the cervix. Gynecol Oncol 1996; 60: 283-287.
42. Fontanini G, Vignati S, Bigini D, et al. Epidermal growth factor receptor (EGFR) expression in non-small cell lung carcinomas correlates with metastatic involvement of hilar and mediastinal lymph nodes in the squamous subtype. Eur J Cancer 1995; 31A: 178-183.
43. Archer SG, Eliopoulos A, Spandidos D, et al. Expression of ras, p21, p53 and c-erb-2 in advanced breast cancer and response to first line hormonal therapy. Br J Cancer 1995; 72: 1259-1266.
44. Seshadri R, McLeay WR, Horsfall DJ, McCaul K. Prospective study of the prognostic significance of epidermal growth factor receptor in primary breast cancer. Int J Cancer 1996; 69: 23-27.
45. Diedrich U, Lucius J, Baron E, Behnke J, Pabst B, Zoll B. Distribution of epidermal growth factor receptor gene amplification in brain tumours and correlation to prognosis. J Neurol 1995; 242: 683-688.
46. Kusukawa J, Harada H, Shima I, Sasaguri Y, Kameyama T, Morimatsu M. The significance of epidermal growth factor receptor and matrix metalloproteinase-3 in squamous cell carcinoma of the oral cavity. Eur J Cancer B Oral Oncol 1996; 32B: 217-221.
47. Christensen ME, Engbaek F, Therkildsen MH, Bretlau P, Nexo E. A sensitive enzyme-linked immunosorbent assay used for quantitation of epidermal growth factor receptor protein in head and neck carcinomas: evaluation, interpretations and limitations. Br J Cancer 1995; 72: 1487-1493.
48. Bergler W, Petroianu G, Juncker C, Hormann K. Correlation of transforming growth factor alpha and epidermal growth factor receptor in oropharyngeal carcinomas. Acta Otolaryngol Stockholm 1996; 116: 486-489.
49. Wen QH, Miwa T, Yoshizaki T, Nagayama I, Furukawa M, Nishijima H. Prognostic value of EGFR and TGF-alpha in early laryngeal cancer treated with radiotherapy. Laryngoscope 1996; 106: 884-888.
50. Nanney LB, Ellis DL, Levine J, King LE. Epidermal growth factor receptors in idiopathic and virally induced skin disease. Am J Pathol 1992; 140: 915-925.
51. Chapman WB, Lorinez AT, Willet GD, Wright WC, Kurman RJ. Epidermal growth factor receptor expression and the presence of human papillomavirus in cervical squamous intraepithelial lesions. Int J Gynecol Pathol 1993; 11: 221-226.
52. Yamada T, Takagi M, Shioda S. Evaluation of epidermal growth factor receptor in squamous cell carcinoma of the oral cavity. Oral Med Oral Surg Oral Pathol 1992; 73: 67-70.
53. Ramael M, Segers K, Buysse C, et al Immunohistochemical distribution patterns of epidermal growth factor receptor in malignant mesothelioma and non-neoplastic mesothelium. Virchows Arch A [Pathol Anat] 1991; 419: 171-175.
54. Maiorano E, Favia GF, Bufo P. Epidermal growth factor receptor expression in squamous papillomas of the oral mucosa. J Biol Res 1993; 3: 195-202.