Growth modulating effects of chlorinated oleic acid in cell cultures

Pharmacology and Toxicology

Volumn 83, Issue 1, 1998, Pages 29-35

  Høstmark, Arne T ^a   Lystad, Einar ^a   Jebens, Einar ^b   Skramstad, Jan ^a   Frøyen, Paul ^c  

^a UNIVERSITY OF OSLO   (Norway)

^b NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH   (Norway)

^c NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORINATED FATTY ACID; CHLORINE; FATTY ACID; OLEIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BREAST MILK; CELL; CELL CULTURE; CELL GROWTH; CONTROLLED STUDY; DIETARY INTAKE; ENDOTHELIUM CELL; FETUS (ANATOMY); FOOD COMPOSITION; FOOD SAFETY; GROWTH INHIBITION; HUMAN; HUMAN CELL; KIDNEY EPITHELIUM; MOTHER; PLACENTA; PRIORITY JOURNAL; TOXICITY TESTING;

EID: 0031866611     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0773.1998.tb01438.x     Document Type: Article

References (19)

1. Adam, M., A. Rodriguez, C. Turbide, J. Larrick, E. Meighen & R. M. Johnstone: In vitro acylation of the transferrin receptor. J. Biol. Chem. 1984, 24, 15460-15463.
2. Bize, I. B., L. W. Oberley & H. R. Morris: Superoxide dismutase and superoxide radical in Morris hepatomas. Cancer Res. 1980, 40, 3686-3692.
3. 3-Lipid peroxides injure CaCo-2 cells: Relationship to the development of reduced glutathione antioxidant systems. Gastroenterology 1994, 107, 80-86.
4. Cunningham, H. M.: Toxicology of compounds resulting from the use of chlorine in food processing. In: Water chlorination: Environmental impact and health effects. Vol. 3. Eds.: R. L. Jolley, W. A. Brungs, R. B. Cummings & V.A. Jacobs. Ann Arbor Science Publishers Inc. Michigan, ISBN 0-250-40342-0, 1980. pp. 995-1005.
5. Ewald, G. & P. Sundin: ATP leakage from EDL cells after exposure to stearic, monochlorostearic, dichlorostearic, and oleic acids. Pharmacology & Toxicology 1993, 73, 159-162.
6. 14C from ingested, radiolabelled dichlorostearic, stearic and oleic acids in body and in lipids of perch Perca fluviatilis. Aquatic Toxicology 1996, 36, 129-139.
7. Göttlicher, M., E. Widmark, Q. Li & J.-Å. Gustafsson: Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor. Proc. Natl. Acad. Sci. USA 1992, 89, 4653-4657.
8. Halliwell, B.: Albumin - an important extracellular antioxidant ? Biochem. Pharmacol. 1988, 37, 569-572.
9. Høstmark, A. T. & E. Lystad: Growth inhibition of human hepatoma cells (HepG2) by polyunsaturated fatty acids. Protection by albumin and vitamin E. Acta physiol. scand. 1992, 144, 83-88.
10. Labarca, C. & K. Paigen: A simple, rapid, and sensitive DNA assay procedure. Anal. Biochem. 1980, 102, 344-352.
11. Mollerup, S. & A. Haugen: Differential effect of polyunsaturated fatty acids on cell proliferation during human epithelial in vitro carcinogenesis: involvement of epidermal growth factor receptor tyrosine kinase. Brit. J. Cancer 1996, 74, 613-618.
12. Mu, H., C. Wesen, T. Novak, P. Sundin, J. Skramstad & G. Odham: Enrichment of chlorinated fatty acids in fish lipids prior to analysis by capillary gas chromatography with electrolytic conductivity detection and mass spectrometry. J. Chromatography A 1996, 731, 225-236.
13. Mu, H., C. Wesen & P. Sundin: Halogenated fatty acids. I. Formation and occurrence in lipids. Trends Anal. Chem. 1997, 16, 226-274 .
14. Oberley, L. W. & G. R. Buettner: Role of superoxide dismutase in cancer. A review. Cancer Res. 1979, 39, 1141-1149.
15. Solanki, V., R. S. Rana & T. J. Slaga: Diminution of mouse epidermal superoxide dismutase and catalase activities by tumor promoters. Carcinogenesis 1981, 2, 1141-1146.
16. Trigatti, L. & G. E. Gerber: A direct role for serum albumin in the cellular uptake of long-chain fatty acids. Biochem. J 1995, 308, 155-159.
17. Wesen, C., H. Mu, A. L. Kvernheim & P. Larsson: Identification of chlorinated fatty acids in fish lipids by partitioning studies and by gas chromatography with Hall electrolytic conductivity detection. J. Chromatography A 1992, 625, 257-269.
18. Wesen, C., H. Mu, P. Sundin, P. Frøyen, J. Skramstad & G. Odham: Gas chromatographic-mass spectrometric identification of chlorinated octadecanoic acids in eel lipids. J. Mass Spectrometry 1995a, 30, 959-968.
19. Wesen, C., P. Sundin, A. L. Kvernheim, H. Mu & G. Odham: Chlorinated fatty acids-the major organochlorine compounds in fish. Scand. J. Nutr. 1995b, 39, 170-174.