메뉴 건너뛰기




Volumn 5, Issue 4, 1998, Pages 911-914

A methylenetetrahydrofolate reductase polymorphism is associated with expression of p16 in human lung cancer

Author keywords

DNA methylation; DNA stability; Lung cancer; Methylenetetrahydrofolate reductase; p16; Polymophism

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); PROTEIN P16;

EID: 0031866088     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: 10.3892/or.5.4.911     Document Type: Article
Times cited : (9)

References (22)
  • 1
    • 0022842769 scopus 로고
    • Role of vitamin B12 and folate deficiencies in carcinogenesis
    • Eto I and Krumdieck CL: Role of vitamin B12 and folate deficiencies in carcinogenesis. Adv Exp Med Biol 206: 313-330, 1986.
    • (1986) Adv Exp Med Biol , vol.206 , pp. 313-330
    • Eto, I.1    Krumdieck, C.L.2
  • 2
    • 0028489042 scopus 로고
    • International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: A critical factor in the maintenance of genetic stability
    • Kunz BA, Kohalmi SE, Kunkel TA, Mathews CK, McIntosh EM and Reidy JA: International Commission for Protection Against Environmental Mutagens and Carcinogens. Deoxyribonucleoside triphosphate levels: a critical factor in the maintenance of genetic stability. Mutat Res 318: 1-64, 1994.
    • (1994) Mutat Res , vol.318 , pp. 1-64
    • Kunz, B.A.1    Kohalmi, S.E.2    Kunkel, T.A.3    Mathews, C.K.4    McIntosh, E.M.5    Reidy, J.A.6
  • 3
    • 0026533906 scopus 로고
    • The pathogenesis of homocysteinemia: Interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine
    • Selhub J and Miller JW: The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine. Am J Clin Nutr 55: 131-138, 1992.
    • (1992) Am J Clin Nutr , vol.55 , pp. 131-138
    • Selhub, J.1    Miller, J.W.2
  • 4
    • 0028487161 scopus 로고
    • Human methylenetetrahydrofolate reductase: Isolation of cDNA, mapping and mutation identification
    • published erratum appears in Nat Genet 7: 551, 1994
    • Goyette P, Sumner JS, Milos R, et al: Human methylenetetrahydrofolate reductase: isolation of cDNA, mapping and mutation identification (published erratum appears in Nat Genet 7: 551, 1994). Nat Genet 7: 195-200, 1994.
    • (1994) Nat Genet , vol.7 , pp. 195-200
    • Goyette, P.1    Sumner, J.S.2    Milos, R.3
  • 5
    • 0029049553 scopus 로고
    • A candidate genetic risk factor for vascular disease: A common mutation in methylenetetrahydrofolate reductase
    • Frosst P, Blom HJ, Milos R, et al: A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase (letter). Nat Genet 10: 111-113, 1995.
    • (1995) Nat Genet , vol.10 , pp. 111-113
    • Frosst, P.1    Blom, H.J.2    Milos, R.3
  • 6
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • Feinberg AP and Vogelstein B: Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301: 89-92, 1983.
    • (1983) Nature , vol.301 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 7
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ and Beach D: A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4 (see comments). Nature 366: 704-707, 1993.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 8
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L, et al: 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers (see comments). Nat Med 1: 686-692, 1995.
    • (1995) Nat Med , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3
  • 9
    • 0028971961 scopus 로고
    • Multiple mechanisms of p16INK4A inactivation in non-small cell lung cancer cell lines
    • Shapiro GI, Park JE, Edwards CD, et al: Multiple mechanisms of p16INK4A inactivation in non-small cell lung cancer cell lines. Cancer Res 55: 6200-6209, 1995.
    • (1995) Cancer Res , vol.55 , pp. 6200-6209
    • Shapiro, G.I.1    Park, J.E.2    Edwards, C.D.3
  • 10
    • 0028971496 scopus 로고
    • Immunohistochemical analysis of the p16INK4 cyclin-dependent kinase inhibitor in malignant mesothelioma
    • Kratzke RA, Otterson GA, Lincoln CE, et al: Immunohistochemical analysis of the p16INK4 cyclin-dependent kinase inhibitor in malignant mesothelioma. J Natl Cancer Inst 87: 1870-1875, 1995.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1870-1875
    • Kratzke, R.A.1    Otterson, G.A.2    Lincoln, C.E.3
  • 11
    • 0029510987 scopus 로고
    • Dual wavelength imaging microdensitometry for immunocytochemical assays in microscopy
    • Bacus JW, Hernicz RS and Bacus JV: Dual wavelength imaging microdensitometry for immunocytochemical assays in microscopy. SPIE 2622: 704-711, 1986.
    • (1986) SPIE , vol.2622 , pp. 704-711
    • Bacus, J.W.1    Hernicz, R.S.2    Bacus, J.V.3
  • 12
    • 0026795472 scopus 로고
    • Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats
    • Cravo ML, Mason JB, Dayal Y, et al: Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats. Cancer Res 52: 5002-5006, 1992.
    • (1992) Cancer Res , vol.52 , pp. 5002-5006
    • Cravo, M.L.1    Mason, J.B.2    Dayal, Y.3
  • 13
    • 0025097846 scopus 로고
    • A population-based case-control study of colorectal cancer in Majorca. I. Dietary factors
    • Benito E, Obrador A, Stiggelbout A, et al: A population-based case-control study of colorectal cancer in Majorca. I. Dietary factors. Int J Cancer 45: 69-76, 1990.
    • (1990) Int J Cancer , vol.45 , pp. 69-76
    • Benito, E.1    Obrador, A.2    Stiggelbout, A.3
  • 15
    • 0030027668 scopus 로고    scopus 로고
    • Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations
    • Jacques PF, Boston AG, Williams RR, et al: Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 93: 7-9, 1996.
    • (1996) Circulation , vol.93 , pp. 7-9
    • Jacques, P.F.1    Boston, A.G.2    Williams, R.R.3
  • 16
    • 0030615085 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer
    • Ma J, Stampfer MJ, Giovannucci E, et al: Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer. Cancer Res 57: 1098-1102, 1997.
    • (1997) Cancer Res , vol.57 , pp. 1098-1102
    • Ma, J.1    Stampfer, M.J.2    Giovannucci, E.3
  • 17
    • 0029919133 scopus 로고    scopus 로고
    • Intragenic mutations of the p16(INK4), p15(INK4B) and p18 genes in primary non-small-cell lung cancers
    • Rusin MR, Okamoto A, Chorazy M, et al: Intragenic mutations of the p16(INK4), p15(INK4B) and p18 genes in primary non-small-cell lung cancers. Int J Cancer 65: 734-739, 1996.
    • (1996) Int J Cancer , vol.65 , pp. 734-739
    • Rusin, M.R.1    Okamoto, A.2    Chorazy, M.3
  • 18
    • 0031057097 scopus 로고    scopus 로고
    • Identification of three distinct tumor suppressor loci on the short arm of chromosome 9 in small cell lung cancer
    • Kim SK, Ro JY, Kemp BL, et al: Identification of three distinct tumor suppressor loci on the short arm of chromosome 9 in small cell lung cancer. Cancer Res 57: 400-403, 1997.
    • (1997) Cancer Res , vol.57 , pp. 400-403
    • Kim, S.K.1    Ro, J.Y.2    Kemp, B.L.3
  • 20
    • 0028829571 scopus 로고
    • Mechanism of inactivation of CDKN2 and MTS2 in non-small cell lung cancer and association with advanced stage
    • Nakagawa K, Conrad NK, Williams JP, Johnson BE and Kelley MJ: Mechanism of inactivation of CDKN2 and MTS2 in non-small cell lung cancer and association with advanced stage. Oncogene 11: 1843-1851, 1995.
    • (1995) Oncogene , vol.11 , pp. 1843-1851
    • Nakagawa, K.1    Conrad, N.K.2    Williams, J.P.3    Johnson, B.E.4    Kelley, M.J.5
  • 21
    • 0028059330 scopus 로고
    • Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
    • published erratum appears in Nat Genet 8: 410, 1994
    • Caldas C, Hahn SA, da Costa LT, et al: Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma (published erratum appears in Nat Genet 8: 410, 1994). Nat Genet 8: 27-32, 1994.
    • (1994) Nat Genet , vol.8 , pp. 27-32
    • Caldas, C.1    Hahn, S.A.2    Da Costa, L.T.3
  • 22
    • 0030765323 scopus 로고    scopus 로고
    • Prognostic value of the immunohistochemical detection of p16INK4 expression in nonsmall cell lung carcinoma
    • Taga S, Osaki T, Ohgami A, et al: Prognostic value of the immunohistochemical detection of p16INK4 expression in nonsmall cell lung carcinoma. Cancer 80: 389-395, 1997.
    • (1997) Cancer , vol.80 , pp. 389-395
    • Taga, S.1    Osaki, T.2    Ohgami, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.