Cell type-specific changes of the membrane properties of peripherally- axotomized dorsal root ganglion neurons in a rat model of neuropathic pain

Neuroscience

Volumn 86, Issue 1, 1998, Pages 301-309

  Kim, Y I ^a   Na, H S ^a   Kim, S H ^a   Han, H C ^a   Yoon, Y W ^a   Sung, B ^a   Nam, H J ^a   Shin, S L ^a   Hong, S K ^a  

^a Korea University College of Medicine   (South Korea)

Author keywords

Action potential; Allodynia; DRG; Hyperalgesia; Neuropathic pain

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE; CELL MEMBRANE DEPOLARIZATION; CELL ULTRASTRUCTURE; MALE; NERVE CELL EXCITABILITY; NERVE FIBER TRANSECTION; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SPINAL GANGLION;

ACTION POTENTIALS; ANIMALS; AXOTOMY; CELL MEMBRANE; DISEASE MODELS, ANIMAL; ELECTRIC STIMULATION; GANGLIA, SPINAL; MALE; NEURAL CONDUCTION; NEURALGIA; NEURONS; NEURONS, AFFERENT; RATS; RATS, SPRAGUE-DAWLEY; SPINAL NERVES;

EID: 0031865637     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00022-0     Document Type: Article

References (31)

1. 2+ channels in axotomized rat sensory neurons. J. Neurosci. 17, 1633-1641.
2. Bennett G. J. and Xie Y. K. (1988) A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man. Pain 33, 87-107.
3. Bonica J. J. (1990) Causalgia and other reflex sympathetic dystrophies. In The Management of Pain (ed. Bonica J. J.), Vol. 2, pp. 220-243. Lea and Fibiger, Philadelphia.
4. Boyd I. A. and Kalu K. U. (1979) Scaling factor relating conduction velocity and diameter for myelinated afferent nerve fibres in the cat hind limb. J. Physiol., Lond. 289, 277-297.
5. Chung K., Kim H. J., Na H. S., Park M. J. and Chung J. M. (1993) Abnormalities of sympathetic innervation in the area of an injured peripheral nerve in a rat model of neuropathic pain. Neurosci. Lett. 162, 85-88.
6. Czéh G., Kudo N. and Kuno M. (1977) Membrane properties and conduction velocity in sensory neurones following central or peripheral axotomy. J. Physiol., Lond. 270, 165-180.
7. Gallego R., Ivorra I. and Morales A. (1987) Effects of central or peripheral axotomy on membrane properties of sensory neurones in the petrosal ganglion of the cat. J. Physiol., Lond. 391, 39-56.
8. Gurtu S. and Smith P. A. (1988) Electrophysiological characteristics of hamster dorsal root ganglion cells and their response to axotomy. J. Neurophysiol. 59, 408-423.
9. Haas H. L., Schaerer B. and Vosmansky M. (1979) A simple perfusion chamber for the study of nervous tissue slices in vitro. J. Neurosci. Meth. 1, 323-325.
10. Harper A. A. and Lawson S. N. (1985) Electrical properties of rat dorsal root ganglion neurones with different peripheral nerve conduction velocities. J. Physiol., Lond. 359, 47-63.
11. Hong S. K., Kim Y. I., Na H. S., Shin S. L., Lee M. G., Nahm S. H. and Han H. C. (1996) Peripherally axotomized DRG cells exhibit altered intrinsic membrane properties in a rat model of neuropathic pain. Soc. Neurosci. Abstr. 22, 866.
12. Jassar B. S., Pennefather P. S. and Smith P. A. (1993) Changes in sodium and calcium channel activity following axotomy of B-cells in bullfrog sympathetic ganglion. J. Physiol., Lond. 472, 203-231.
13. Kajander K. C. and Bennett G. J. (1992) Onset of a painful peripheral neuropathy in rat: a partial and differential deafferentation and spontaneous discharge in Αβ and Αδ primary afferent neurons. J. Neurophysiol. 68, 734-744.
14. Kelly M. E., Gordon T., Shapiro J. and Smith P. A. (1986) Axotomy affects calcium-sensitive potassium conductance in sympathetic neurones. Neurosci. Lett. 67, 163-168.
15. Kim Y. I., Na H. S., Han J. S. and Hong S. K. (1995) Critical role of the capsaicin-sensitive nerve fibers in the development of the causalgic symptoms produced by transecting some but not all of the nerves innervating the rat tail. J. Neurosci. 15, 4133-4139.
16. Kim Y. I, Na H. S., Yoon Y. W., Nahm S. H., Ko K. H. and Hong S. K. (1995) Mechanical allodynia is more strongly manifested in older rats in an experimental model of peripheral neuropathy. Neurosci. Lett. 199, 158-160.
17. Kim H. J., Na H. S., Nam H. J., Park K. A., Hong S. K. and Kang B. S. (1996) Sprouting of sympathetic nerve fibers into the dorsal root ganglion following peripheral nerve injury depends on the injury site. Neurosci. Lett. 212, 191-194.
18. Kostyuk P. G., Veselovsky N. S. and Tsyndrenko A. Y. (1981) Ionic currents in the somatic membrane of rat dorsal root ganglion neurones. I. Sodium currents. Neuroscience 6, 2423-2430.
19. Lee K. H., Chung K., Chung J. M. and Coggeshall R. E. (1986) Correlation of cell body size, axon size, and signal conduction velocity for individually labelled dorsal root ganglion cells in the cat. J. comp. Neurol. 243, 335-346.
20. McLachlan E. M., Jänig W., Devor M. and Michaelis M. (1993) Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia. Nature 363, 543-546.
21. Na H. S., Han J. S., Ko K. H. and Hong S. K. (1994) A behavioral model for peripheral neuropathy produced in rat's tail by inferior caudal trunk injury. Neurosci. Lett. 177, 50-52.
22. Na H. S., Kim Y. I., Ko K. H. and Hong S. K. (1995) The role of signals from dorsal root ganglion in neuropathic pains induced by nerve injury. Soc. Neurosci. Abstr. 21, 896.
23. Petersen M., Zhang J., Zhang J.-M. and LaMotte R. H. (1996) Abnormal spontaneous activity and responses to noradrenaline in dissociated dorsal root ganglion cells after chronic nerve constriction. Pain 67, 391-397.
24. + currents in cutaneous afferent dorsal root ganglion neurons following axotomy. Neurobiol. Dis. 2, 87-96.
25. Sheen K. and Chung J. M. (1993) Signs of neuropathic pain depend on signals from injured nerve fibers in a rat model. Brain Res. 610, 62-68.
26. Study R. E. and Krai M. G. (1996) Spontaneous action potential activity in isolated dorsal root ganglion neurons from rats with a painful neuropathy. Pain 65, 235-242.
27. Villière V. and McLachlan E. M. (1996) Electrophysiological properties of neurons in intact rat dorsal root ganglia classified by conduction velocity and action potential duration. J. Neurophysiol. 76, 1924-1941.
28. Wall P. D. and Devor M. (1983) Sensory afferent impulses originate from dorsal root ganglia as well as from the periphery in normal and nerve injured rats. Pain 17, 321-339.
29. Waxman S. G., Kocsis J. D. and Black J. A. (1994) Type III sodium channel mRNA is expressed in embryonic but not adult spinal sensory neurons, and is re-expressed following axotomy. J. Neurophysiol. 72, 466-470.
30. Xie Y., Zhang J., Petersen M. and LaMotte R. H. (1995) Functional changes in dorsal root ganglion cells after chronic nerve constriction in the rat. J. Neurophysiol. 73, 1811-1820.
31. Yoon Y. W., Na H. S. and Chung J. M. (1996) Contributions of injured and intact afferents to neuropathic pain in an experimental rat model. Pain 64, 27-36.