Expression of epidermal growth factor receptor family proteins (EGFR, c-erbB-2 and c-erbB-3) in gastric cancer and chronic gastritis

Anticancer Research

Volumn 18, Issue 4 A, 1998, Pages 2727-2732

  Slesak, B ^a   Harlozinska, A ^a   Porebska, I ^a   Bojarowski, T ^a   Lapinska, J ^a   Rzeszutko, M ^a   Wojnar, A ^b  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b Oncological Center   (Poland)

Author keywords

c erbB 2; c erbB 3 expression; Chronic gastritis; EGFR; Gastric cancer; Intestinal metaplasia

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR;

ARTICLE; CHRONIC GASTRITIS; CLINICAL ARTICLE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; ONCOGENE C ERB; PRIORITY JOURNAL; STOMACH CANCER;

ADENOCARCINOMA; ANTIBODIES, MONOCLONAL; BIOPSY; CARCINOMA; GASTRECTOMY; GASTRIC MUCOSA; GASTRITIS; HUMANS; IMMUNOHISTOCHEMISTRY; METAPLASIA; PROTO-ONCOGENE PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECEPTOR, ERBB-3; STOMACH NEOPLASMS;

EID: 0031865433     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Cantley LC, Auger KR, Carpenter C, Duckworth B, Graziani A, Kapeller R and Soltoff S: Oncogenes and signal transduction. Cell 64: 281-302, 1991.
2. Stemmermann G, Heffelfinger SC, Noffsinger A, Hui YZ, Miller MA and Fenoglio-Preiser CM. The molecular biology of esophageal and gastric cancer and their precursors: Oncogenes, tumor suppressor genes, and growth factors. Hum Pathol 25: 968-981, 1994.
3. Tahara E: Growth factors and oncogenes in human gastrointestinal carcinomas. J Cancer Res Clin Oncol 116: 121-131, 1990.
4. Ullrich A and Schlessinger J: Signal transduction by receptors with tyrosine kinase activity. Cell 61: 203-212, 1990.
5. Barnard JA, Beauchamp RD, Russell WE, Dubois RN and Coffey RJ: Epidermal growth factor-related peptides and their relevance to gastrointestinal pathophysiology. Gastroenterology 108: 564-580, 1995.
6. Gullick WJ: The c-erbB-3/HER 3 receptor in human cancer. Cancer Surv 27: 339-349, 1996.
7. Brand-Rauf PW, Pincus MR and Carney WP: The c-erbB-2 protein in oncogenesis: Molecular structure to molecular epidemiology. Crit Rev Oncogenesis 5: 313-329, 1994.
8. Harlozinska A, Bar JK, Wenderski R and Bebenek M: Relationship between c-erbB-2 oncoprotein, epidermal growth factor receptor, and estrogen receptor expression in patients with ductal breast carcinoma. Association with tumor phenotypes. In Vivo 10: 217-222, 1996.
9. Harlozinska A, Bar JK, Sobanska E and Goluda M: EGFR and c-erbB-2 oncoproteins in tissue and tumor effusion cells of histopathologically different ovarian neoplasms. Tumor Biol, 1998 in press.
10. Modjtahedi H and Dean Ch: The receptor for EGF and its ligands: Expression, prognostic value and target for therapy in cancer (Review). Int J Oncol 4: 277-296, 1994.
11. Rajkumar T, Stamp GWH, Pandha HS, Waxman J and Gullick WJ: Expression of the type I tyrosine kinase growth factor receptors: EGF receptor, c-erbB-2 and c-erbB-3 in bladder cancer. J Pathol 179: 381-385, 1966.
12. Haugen DRF, Akslen LA, Varhaug JE and Lillehaug JR: Expression of c-erbB-3 and c-erbB-4 proteins in papillary thyroid carcinomas. Cancer Res 56: 1184-1188, 1996.
13. Rajkumar T, Stamp GWH, Hughes CM and Gullick WJ: c-erbB-3 protein expression in ovarian cancer. J Clin Pathol Mol Pathol 49: M199-M202, 1966.
14. Jain S, Filipe I, Gullick WJ, Linehan J and Morris RW: c-erbB-2 protooncogene expression and its relationship to surrival in gastric carcinoma: an immunohistochemical study on archival material. Int J Cancer 48: 668-671, 1991.
15. Ohguri T, Sato Y, Koizumi W, Saigenji K and Kameya T: An immunohistochemical study of c-erbB-2 protein in gastric carcinomas and lymph-node metastases: is the c-erbB-2 protein really a prognostic indicator? Int J Cancer 53: 75-79, 1993.
16. Sasano H, Date F, Imatani A, Asaki S and Nagura H: Double immunostaining for c-erbB-2 and p53 in human stomach cancer cells. Hum Pathol 24: 584-589, 1993.
17. Sugiyama K, Yonemura Y and Miyazaki I: Immunohistochemical study of epidermal growth factor and epidermal growth factor receptor in gastric carcinoma. Cancer 63: 1557-1561, 1989.
18. Correa P: Human gastric carcinogenesis: A multistep and multifactorial process-first American Cancer Society Award Lecture on cancer epidemiology and prevention. Cancer Res 52: 6735-6740, 1992.
19. Kolodziejczyk P, Yao T, Oya M, Nakamura S, Utsunomiya T, Ishikawa T and Tsuneyoshi M: Long term follow-up study of patients with gastric adenomas with malignant transformation. An immunohistochemical and histochemical analysis. Cancer 74: 2896-2907, 1994.
20. Lemoine NR, Jain S, Silvestre F, Lopes C, Hughes CM, McLelland E, Gullick WJ and Filipe MI: Amplifications and overexpression of the EGF receptor and c-erbB-2 protooncogenes in human stomach cancer. Brit J Cancer 64: 79-83, 1991.
21. Wright PA and Williams GT: Molecular biology and gastric carcinoma. Gut 34: 145-147, 1993.
22. Choi J-H, Oh JY, Ryu SK, Kim SJ, Lee NY, Kim YS, Yi SY, Shim KS and Han WS: Detection of epidermal growth factor receptor in the serum of gastric carcinoma patients, Cancer 79: 1879-1883, 1997.
23. c-ebB-2. Oncology 52: 385-391, 1995.
24. Lee EY, Cibull ML, Strodel WE and Haley JV: Expression of HER-2/neu oncoprotein and epidermal growth factor receptor and prognosis in gastric carcinoma. Arch Pathol Lab Med 118: 235-239, 1994.
25. Lee HR, Kim J-H, Uhm HD, Ahn JB, Rha SY, Cho JY, Lee JI, Lee KH, Chung HCh, Roh JK, Min JS, Lee KS, Shin DH, Kim BS, Kim BS, Hong SW and Choi J-H: Overexpression of c-erbB-2 protein in gastric cancer by immunohistochemical stain. Oncology 53: 192-197, 1996.
26. Mizutani T, Onda M, Tokunaga A, Yamanaka N and Sugisaki Y: Relationship of c-erbB-2 protein expression and gene amplification to invasion and metastasis in human gastric cancer. Cancer 72: 2083-2088, 1993.
27. Tsugawa K, Fushida S and Yonemura Y: Amplification of the c-erbB-2 gene in gastric carcinoma: Correlation with survival. Oncology 50: 418-425, 1993.
28. Uchino S, Tsuda H, Maruyama K, Kinoshita T, Sasako M:, Saito T, Kobayashi M and Hirohashi S: Overexpression of c-erbB-2 protein in gastric cancer. Its correlation with long term survival of patients. Cancer 72: 3179-3184, 1993.
29. Rajkumar T, Goden CSR, Lemoine NR and Gullick WJ: Expression of the c-erhB-3 protein in gastrointestinal tract tumours determined by monoclonal antibody RTJ1. J Pathol 170: 271-278, 1993.
30. Chiu KY, Loke SL and Ho FCS: Immunohistochemical demonstration of c-erbB-2 oncoprotein in gastric adenocarcinoma: Comparison of cryostat and paraffin wax sections and effect of fixation. J Clin Pathol 47: 117-121, 1994.
31. Tannapfel A., Kuhn R, Kessler H and Wittekind Ch: Expression of c-erbB-2 oncogene product in different tumours and its standardised evaluation. Anal Cell Pathol 10: 149-160, 1996.
32. Lin J-T, Wu M-S, Shun Ch-T, Lee W-J, Sheu J-Ch and Wang T-H: Occurence of microsatellite instability in gastric carcinoma is associated with enhanced expression of c-erbB-2 oncoprotein. Cancer Res 55: 1428-1430, 1995.
33. Sanidas EE, Filipe MI, Linehan J, Lemoine NR, Gullick WJ, Rajkumar T and Levison DA: Expression of the c-erbB-3 gene product in gastric cancer. Int J Cancer 54: 935-940, 1993.