Intraparticle diffusion alters the dynamic response of immobilized cell/enzyme columns

Bioprocess Engineering

Volumn 18, Issue 6, 1998, Pages 419-426

  Papathanasiou, T D ^a   Bijeljic, B ^b  

^a University of South Carolina   (United States)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOREACTOR; ENZYME IMMOBILIZATION; FERMENTATION; IMMOBILIZED CELL; PRIORITY JOURNAL; TECHNOLOGY;

EID: 0031864648     PISSN: 0178515X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004490050465     Document Type: Article

References (20)

1. Papathanasiou, T.D.; Kalogerakis, N.; Behie L.A.; Gaucher, G.M.; Thibault, J.: Modelling the dynamic behaviour of immobilized cell/enzyme bioreactors: The tanks-in series model. In: Ho, C.S and Oldshue, J.(Eds): Biotechnology processes: Scale-up and Mixing pp. 238-248. New York: 1987
2. Papathanasiou, T.D.; Kalogerakis, N.; Behie, L.A.: Dynamic modelling of mass transfer phenomena with chemical reaction in immobilized-enzyme bioreactors. Chem. Eng. Sci. 43 (1988) 1489-1498
3. Cheryan, M.; Mehaia, M.: Membrane bioreactors. In: McGregor, W.C. (Ed.): Membrane Separations in Biotechnology, pp. 255-301. New York: Marcel Dekker, Inc. 1986
4. Bailey, J.E.; Ollis, D.F.: Biochemical Engineering Fundamentals. New York: McGraw-Hill, Inc. 2nd edition 1986
5. Ishimura, P.; Suga, K.: New bioreactor for fibrous support and hydrolysis of penicillin G. J. Chem. Eng. Jap. 28 (1995) 443-448
6. Gilson, C.D; Thomas, A: Ethanol production by alginate immobilised yeast in a fluidized bed reactor. J. Chem. Tech. Biotechnol. 62 (1995) 38-45
7. Dueck, C.L.; Neufeld, R.J.; Chang, T.M.S.: Hydrodynamics and urea hydrolysis in a microcapsulated urease, fluidized bed reactor. Can. J. Chem. Eng. 64 (1986) 540-546
8. Godia, F.; Casas, C.; Sola, C.: A survey of continuous ethanol fermentation systems using immobilized cells. Proc. Biochem. 22 (1987) 43-48
9. Mazid, M.A.: Biocatalysis and Immobilized Enzyme/Cell Bioreactors. Biotechnol. 11 (1993) 690-695
10. Levenspiel, O.: Chemical Reaction Engineering. New York: John Wiley & Sons, Inc. 2nd edition 1972
11. Sherwood, T.K.; Pigford, R.L.; Wilke C.R.: Mass Transfer. New York: McGrawHill, Inc. 3rd edition 1975
12. Nelson, P.A.; Galloway, T.R.: Particle-to fluid heat and mass transfer in dense systems of fine particles. Chem. Eng. Sci. 30 (1975) 1-6
13. De Backer, L.; Baron G.: Residence time distribution in a packed bed bioreactor containing porous glass particles: influence of the presence of immobilized cells. J. Chem. Tech. Biotechnol. 59 (1995) 297-302
14. Tanaka, H.; Matsumura, M.; Veliky, I.A.: Diffusion characteristics of substrates in Ca-alginate beads. Biotechnol. Bioeng. 26 (1984) 53-58
15. Berk, D.; Behie, L.A.; Jones, A.; Lesser, B.H.; Gaucher, G.M.: The production of the antibiotic patulin in a three phase fluidized bed reactor I. Effect of medium composition. Can. J. Chem. Eng. 62 (1984) 112-119
16. Crank J.: The Mathematics of Diffusion London: Oxford university press, 3rd edition 1983
17. Carslaw, H.S.; Jaeger J.C.: Conduction of heat in solids. London: Oxford University Press, 2nd edition 1959
18. Gear, C.W.: Numerical Initial Value Problems in Oridinary Differential Equations. London: Prentice Hall 1971
19. Chung, S.F.; Wen C.Y.: Longitudinal dispersion of liquid flowing through fixed and fluidized beds. AIChE Journal 14 (1968) 857-866
20. Cramers, H.; Alberd, G.: Frequency response analysis of continuous flow systems. Chem. Eng. Sci. 2 (1953) 173