Altered myocardial vasodilatation in patients with hypertriglyceridemia in anatomically normal coronary arteries

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 18, Issue 2, 1998, Pages 294-299

  Yokoyama, Ikuo ^a   Ohtake, Tohru ^a   Momomura, Shin Ichi ^a   Yonekura, Katsunori ^a   Kobayakawa, Naoshi ^a   Aoyagi, Teruhiko ^a   Sugiura, Seiryo ^a   Sasaki, Yasuhito ^a   Omata, Masao ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Atherosclerosis; Hyperlipidemia; Hypertriglyceridemia; Myocardial vasodilatation PET

Indexed keywords

CHOLESTEROL; DIPYRIDAMOLE; TRIACYLGLYCEROL;

ADULT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DILATATION; FEMALE; HEART MUSCLE BLOOD FLOW; HUMAN; HYPERLIPIDEMIA; HYPERTRIGLYCERIDEMIA; MALE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0031862372     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.18.2.294     Document Type: Article

References (20)

1. Gould KL, Lipscomb K. Effects of coronary stenoses on coronary flow reserve and resistance. Am J Cardiol. 1974;34:48-54.
2. Yokoyama I, Ohtake T, Murakami T, Momomura S, Nishikawa J, Sasaki Y, Omata M. Reduced coronary flow reserve in familial hypercholesterolemia. J Nucl Med. 1996;37:1937-1942.
3. Dayanikli F, Grambow D, Muzil O, Mosca L, Rubenfire M, Schwaiger M. Early detection of abnormal coronary flow reserve in asymptomatic men at high risk for coronary artery disease using positron emission tomography. Circulation. 1994;90:808-817.
4. Pitkaenen OP, Raitakari OT, Niinikoshi H, Nuutila P, lida H, Voipio-Pulkki LS, Haerkoenen R, Wegelius U, Roennemaa T, Viikari J, Kunuuti J. Coronary flow reserve is impaired in young men with familial hypercholesterolemia. J Am Coll Cardiol. 1996;28:1705-1711.
5. Yokoyama I, Ohtake T, Momomura S, Nishikawa J, Sasaki Y, Omata M. Myocardial insulin resistance related to coronary atherosclerosis in patients with insulin resistance syndrome. J Nucl Med. 1996;36:38P. Abstract.
6. Camici PG, Chiriatti G, Lorenzoni R, Bellina RC, Gistri R, Italiani G. Coronary vasodilation is impaired in both hypertrophied and nonhypertrophied myocardium of patients with hypertrophic cardiomyopathy: a study with nitrogen-13 ammonia and positron emission tomography. J Am Coll Cardiol. 1991;17:879-886.
7. Inoue T, Sasaki Y, Morooka S, Hayashi T, Takayanagi K, Yamanaka T, Kakoki H, Takabatake Y. Coronary flow reserve in patients with dilated cardiomyopathy. Am Heart J. 1993;125:93-98.
8. Nitenberg A, Valensi P, Sachs R, Dalim M, Aptecar E, Attali JR. Impairment of coronary vascular reserve and Ach-induced coronary vasodilation in diabetic patients with angiographically normal coronary arteries and normal ventricular systolic function. Diabetes. 1993;32:1017-1023.
9. Nahser PJ Jr, Brown RE, Oskarsson H, Winnifold MD, Rossen JD. Maximal coronary flow reserve and metabolic coronary vasodilation in patients with diabetes mellitus. Circulation. 1995;91:635-640.
10. Yokoyama I, Ohtake T, Momomura S, Yonekura K, Nishikawa J, Sasaki Y, Omata M. Reduced myocardial flow reserve in patients with noninsulin dependent diabetes. J Am Coll Cardiol. 1997;30:1472-1477.
11. Uren NG, Crake T, Leffery DC, Silva R, Gavies GJ, Maseri A. Reduced coronary vasodilator function in infarcted and normal myocardium after myocardial infarction. N Engl J Med. 1994;331:222-227.
12. Yokoyama I, Ohtake T, Momomura S, Nishikawa J, Sasaki Y, Omata M. Reduced coronary flow reserve in hypercholesterolemic patients without overt coronary stenosis. Circulation. 1996;94:3232-3238.
13. 13N] Ammonia myocardial imaging at rest and with exercise in normal volunteers. Circulation. 1989;80:1328-1337.
14. 13N]ammonia and reoriented dynamic positron emission tomography. Circulation. 1992;86:1004-1017.
15. Mintz GS, Painter JA, Pichard AD, Kent KM, Satler LF, Popma JJ, Chuang YC, Bucher TA, Sokolowicz LE, Leon MB. Atherosclerosis in angiographically normal coronary artery reference segments: an intravascular ultrasound study with clinical correlations. J Am Coll Cardiol. 1995;25: 1479-1485.
16. Cohen RA, Zitnay KM, Haudenshild CC, Cunningham LD. Loss of selective endothelial cell vasoactive functions caused by hypercholesterolemia in pig coronary arteries. Circ Res. 1988;63:903-910.
17. Osbornc JA, Siegman MJ, Sedar AW, Mooers SU, Lefer AM. Lack of endothelium-dependent relaxation in coronary resistance arteries of cholesterol-fed rabbits. Am J Physiol. 1989;256:C591-C597.
18. Drexler H, Zeiher AM, Meinzer K, Just H. Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolemic patients by L-arginine. Lancet. 1991;338:1546-1549.
19. Zeiher AM, Drexler H, Wollschheger H, Just H. Modulation of coronary vasomotor tone in humans: progressive endothelial dysfunction with different early stages of coronary atherosclerosis. Circulation. 1991;83:391-401.
20. Drexler H, Zeiher AM. Endothelial function in human coronary arteries in vivo. Focus on hypercholesterolemia. Hypertension. 1991;18(suppl II):II-90-11-99.