Helicobacter pylori y dispepsia no ulcerosa: Una asignatura pendiente

Revista Espanola de Enfermedades Digestivas

Volumn 90, Issue 6, 1998, Pages 441-453

  Gisbert, Javier P ^a,b   Boixeda, D ^a   Martin de Argila C ^a   Garcia Plaza A ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b NONE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; BISMUTH; ERYTHROMYCIN; METRONIDAZOLE; NITROFURANTOIN; OMEPRAZOLE; TETRACYCLINE;

ANTIBIOTIC THERAPY; DYSPEPSIA; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; HUMAN; REVIEW;

DYSPEPSIA; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS;

EID: 0031862221     PISSN: 11300108     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (210)

1. Talley NJ, Colins-Jones D, Koch M, et al. Functional dyspepsia: a classification with guidelines for diagnosis and management. Gastroenterol Int 1991;4:145-60.
2. Heading RC. Definitions of dyspepsia. Scand J Gastroenterol 1991;26(Suppl 182):1-6.
3. Dyspepsia Working Party. AGA Meeting. Chicago. Management of dyspepsia: report of a working party. Lancet 1988;1:576-9.
4. Cheli R, Perusso A, Giacosa A. Dyspepsia and chronic gastritis. Hepatogastroenterol 1983;30:21-3.
5. Siurala M, Isokoski M, Varis K, et al. Prevalence of gastritis in a rural population: biopsie study of subjects selected at radom. Scand J Gastroenterol 1968;3:211-23.
6. Tytgat GNJ, Noach LA, Rauws EAJ. Is gastroduodenitis a cause of chronic dyspepsia? Scand J Gastroenterol 1991;Suppl 182:33-9.
7. Kreuning J, Bosman FT, Kuiper I, Van der Wal AM, Lindeman J. Gastric and duodenal mucosa in "healthy" individuals: an endoscopic and histopathological study of 50 volunteers. J Clin Pathol 1978;31:69-77.
8. Ihamäki T, Saukkonen M, Diurala M. Long-term observation of subjects with normal mucosa and with superficial gastritis: results of 23-27 years' follow-up examinations. Scand J Gastroenterol 1978;13:771-5.
9. Villako, K, Tamm A, Savisaar E, et al. Prevalence of antral and rundic gastritis in a randomly selected group of an Estonian rural population. Scand J Gastroenterol 1976;11:817-22.
10. Villako K, Ihamäki T, Tamm A, et al. Upper abdominal complains and gastritis. Ann Clin Res 1984;16:192-5.
11. Siurala M, Sipponen P, Kekki M. Chronic gastritis: dynamic and clinical aspects. Scand J Gastroenterol 1985;20(Suppl 109):69-76.
12. Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1984;1:1311-5.
13. Schubert TT, Schuer AB, Ma CK. Symtoms, gastritis, and Helicobacter pylori in patients referred for endoscopy. Gastrointest Endosc 1992;38:357-60.
14. Gisbert JP, Boixeda D, Álvarez Baleriola I, et al. Evolución de las lesiones histológicas de la mucosa gástrica tras la erradicación de Helicobacter pylori en pacientes con úlcera duodenal. Estudio inicial y a los 6 meses. Rev Esp Enferm Dig 1995;87:281-7.
15. Marshall BJ, McGehie DB, Rogers PA, et al. Pyloric campylobacter infection and gastroduodenal disease. Med J Aust 1985;142:439-42.
16. Cadranel S, Goossens H, De Boeck M, et al. Campylobacter pyloridis in children. Lancet 1986;1:735.
17. Rokkas T, Pursey C, Uzoechina E, et al. Campylobacter pylori and non-ulcer dyspepsia. Am J Gastroenterol 1987;82:1149-52.
18. Andersen LP, Elsborg L, Justesen T. Campylobacter pylori in peptic ulcer disease. III. Symptoms and paraclinical and epidemiologic findings. Scand J Gastroenterol 1988;23:347-50.
19. Rathbone BJ, Wyatt J, Heatley RV Symptomatology in Campylobacter pylori positive and negative non-ulcer dyspepsia. Gut 1988;29:A1473.
20. Thomas J, Eastham EJ, Elliot TSJ, et al. Campylobacter pylori gastritis in children - A common cause of symptoms? Gut 1988;29:A707.
21. Börsch G, Schmidt G, Wegener M, et al. Campylobacter pylori: prospective analysis of clinical and histological factors associated with colonization of the upper gastrointestinal tract. Eur J Clin Invest 1988;18:133-8.
22. Rauws EAJ, Langenberg W, Houthoff HJ, Zanene HC, Tytgat GNJ. Campylobacter pylori -associated chronic active antral gastritis. A prospective study of its prevalence and the effects of antibacterial and antiulcer treatment. Gastroenterology 1988;4:33-40.
23. Lambert JR, Dunn K, Borromeo M. Campylogacter pylori - A role in non-ulcer dyspepsia? Scand J Gastroenterol 1989;Suppl 160:7-13.
24. Deltenre M, Nyst JF, Jonas C, et al. Données cliniques endoscopyques et histologiques chez 1100 patients dont 574 colonisés par Campylobacter pylori. Gastroenterol Clin Biol 1989;13:89-95.
25. Loffeld RJLF, Potters HVPJ, Arends JW, et al. Campylobacter associated gastritis in patients with non-ulcer dyspepsia. J Clin Pathol 1988;41:85-8.
26. Pettross CW, Appleman MD, Cohen H, Valenzuela JE, Chandrasoma P, Laine LA. Prevalence of Campylobacter pylori and association with antral mucosal histology in subjects with and without upper gastrointestinal symptoms. Dig Dis Sci 1988:649-53.
27. Inouye H, Yamamoto I, Taida N. Campylobacter pylori in Japan: bacteriological features and prevalence in healthy subjects and patients with gastroduodenal disorders. Gastroenterol Jpn 1989;24:494-504.
28. George A, Dooley CP, Dehesa M, et al. Evidence against a role for Campylobacter pylori in the pathogenesis of non-ulcer dyspepsia. Gastroenterology 1989;96:170.
29. Sobala GM, Dixon MF, Axon ATR. Symptomatology of Helicobacter pylori-associated dyspepsia. Eur J Gastroenterol Hepatol 1990;2:445-9.
30. Strauss RM, Wang TC, Kelsey PB. Association of Helicobacter pylori infection with dyspeptic symptoms in patients undergoing gastroduodenoscopy. Am J Med 1990;89:464-9.
31. Vaira K, Holton J, Osborn J. Endoscopy in dyspeptic patient: is gastric mucosal biopsy useful? Am J Gastroenterol 1990;85:701-4.
32. Collins JSA, Knill-Jones RP, Sloan JM, et al. A comparison of symptoms between non-ulcer dyspepsia patients positive and negative for Helicobacter pylori. Ulster Med J 1991;60:21-7.
33. O'Riordan TG, Tobin A, O'Morain C. Helicobacter pylori infection in elderly dyspeptic patients. Age Ageing 1991;20:189-92.
34. Tucci A, Corinaldesi R, Stanghellini V, et al. Helicobacter pylori infection and gastric function in patients with chronic idiopathic dyspepsia. Gastroenterology 1992;103:768-74.
35. Bernersen B, Johnsen R, Bostad L, Straume B, Sommer AI, Burhol PG. Is Helicobacter pylori the cause of dyspepsia? Br Med J 1992;304:1276-9.
36. Rohrbach MA, Ferguson DA Jr, Farum JB, Thomas E. Chronic gastritis associated with infection due to Helicobacter pylori in Southern Appalachian veterans with dyspepsia. South Med J 1993;86:1354-9.
37. Archimandritis A, Bistsikas J, Tjivras M, et al. Helicobacter pylori infection in Greece in healthy people and in patients with peptic ulcer with dyspepsia without ulcer. J Clin Gastroenterol 1993;16:257-8.
38. Trespi E, Broglin F, Villani L, et al. Distinct profiles of gastritis in dyspepsia subgroups. Their different clinical responses to gastritis healing after Helicobacter pylori eradication. Scand J Gastroenterol 1994;29:884-8.
39. Agréus L, Engstrand L, Svärdsudd K, Nyrén O, Tibblin G. Helicobacter pylori seropositivity among Swedish adults with and without abdominal symptoms. A population-based epidemiologic study. Scand J Gastroenterol 1995;30:752-7.
40. Elta GH, Scheiman JM, Barnett JL, et al. Long-term follow-up of Helicobacter pylori treatment in non-ulcer dyspepsia patients. Am J Gastroenterol 1995;90:1089-93.
41. Holtmann G, Goebell H, Hüber J, Talley NJ. Helicobacter pylori and sensory dysfunction in patients with functional dyspepsia and healthy conrols. Gastroenterology 1995;108:A615.
42. Schlemper RL, Van der Werf DJ, Vanderbrouche JP, Biemond I, Lamers CBHW. Non-ulcer dyspepsia in a Dutch working population and Helicobacter pylori. Ulcer history as an explanation of an apparent association. Arch Inter Med 1995;155:82-7.
43. Bardhan PK, Islam M, Mahalanabis D, Gyr K. A study of Helicobacter pylori in Bangladesh subjects with non-ulcer dyspepsia. Gut 1994;35(Suppl 5):S20.
44. Fock KM, Chong W, Khin MM, Ng HC, Viayakumari S, Ho B. Prevalence of Helicobacter pylori in functional dyspspesia in Singapore as determined by histology and western blot. Gut 1994;35(Suppl 5):S23.
45. Lee HR, Han KS, Yoo BC, Park SM. Prevalence of Helicobacter pylori infection in patients with peptic ulcer diseases and nonulcer dyspepsia. Korean J Intern Med 1993;8:73-7.
46. Wilhelmsen I, Tangen Haug T, Sipponen P, Berstad A. Helicobacter pylori in functional dyspepsia and normal controls. Scand J Gastroenterol 1994;29:522-7.
47. Andersson SI, Hovelius B, Molstad S, Wadstrom T. Dyspepsia in general practice: psychological findings in relation to Helicobacter pylori serum antibodies. J Psychosom Res 1994;38:241-7.
48. Boixeda D, Gisbert JP, Martín de Argila C, Cantón R, Bermejo F, García Plaza A. ?Existe alguna relación entre la sintomatología digestiva y la infección por Helicobacter pylori? Rev Esp Enferm Dig 1995;87:8-14.
49. Gutiérrez D, Sierra F, Gómez MC, Camargo H. Campylobacter pylori in chrome environmental gastritis and duodenal ulcer patients. Gastroenterology 1988;94:A163.
50. Collins JSA, Hamilton PW, Watt PCH, Sloan JM, Love AHG. Superficial gastritis and Campylobacter pylori in dyspeptic patients - A quantitative study using computer-linked image analysis. J Pathol 1989;150:303-10.
51. Wilberg S, Pieramico O, Malfertheimer P. Role of antral inflammation on orocecal transit time on patients witn non-ulcer dyspepsia. Klin Wochenschr 1989;67(Suppl 18):72.
52. Lambert JR. The role of Helicobacter pylori in non-ulcer dyspepsia: a debate-for. In: Dooley CP, Cohen H (Eds). Helicobacter pylori infection. Gastroenterol Clin North Am. Philadelphia: WB Saunders; 1993. p. 141-51.
53. Armstrong D. Helicobacter pylori infection and dyspepsia. Scand J Gastroenterol 1996;31(Suppl 215):38-47.
54. Buckely M, O'Morain C. Prevalence of Helicobacter pylori in nonulcer dyspepsia. Aliment Pharmacol Ther 1995;9 (Suppl 2):53-8.
55. Wyatt JI, Rathbone BJ, Heatley RV, et al. Campylobacter pylori and history of dyspepsia in blood donors. Gut 1988;29:A706.
56. Skglund ML, Whalen JW. Correlation of Campylobacter and upper gastrointestinal symptoms. Gastroenterology 1988;94:A430.
57. Holtman G, Goebell H, Holtmann M, Gschossmann J, Hüber J, Talley NJ. Helicobacter pylori and functional dyspepsia: increased serum antibodies an independent risk factor. Gastroenterology 1995;108:A116.
58. El-Omar E, Baneriee S, Wirz A, McColl KEL. Helicobacter pylori infection and dyspepsia within the general population. Gut 1995;37(Suppl 1):A11.
59. Siurala M, Sipponen P, Kekki M. Campylobacter pylori in a sample of Finnish population: relations to morphology and functions of the gastric mucosa. Gut 1988;29:909-12.
60. Czinn SJ, Bertram TA, Murray PD, Yang P. Relationship between gastric inflammatory response and symptoms in patients infected with Helicobacter pylori, Scand J Gastroenterol 1991;26(Suppl 181):33-8.
61. De Luca VA. No acid, no polyps. No "active", no dyspepsia: a proposal. J Clin Gastroenterol 1989;18:127-31.
62. Toukan AU, Kamal MF, Amr SS, et al. Gastroduodenal inflammation in patients witn non-ulcer dyspepsia: a controlled endoscopic and morphometric study. Dig Dis Sci 1985;30:313-6.
63. Talley NJ. The role of Helicobacter pylori in non-ulcer dyspepsia: a debate-against. In: Dooley CP, Cohen H (Eds). Helicobacter pylori infection. Gastroenterol Clin North Am. Philadelphia: WB Saunders; 1993. p. 153-67.
64. Johnsen R, Bernersen B, Straume B, et al. Prevalence of endoscopic and histological findings in subjects with and without dyspepsia. Br Med J 1991;302:749-52.
65. Jonsson KA, Gotthard R, Bodemar G, et al. The clinical relevance of endoscopic and histologic inflammation of gastroduodenal mucosa in dyspepsia of unknown origin. Scand J Gastroenterol 1989;24:385-95.
66. Holtmann G, Goebell H, Holtmann M, Talley NJ. Dyspepsia in healthy blood donors: pattern of symptoms and association with Helicobacter pylori. Dig Dis Sci 1994;39:1090-8.
67. Greenberg RE, Bank S. The prevalence of Helicobacter pylori in nonulcer dyspepsia. Importance of stratification according to age. Arch Intern Med 1990;150:2053-5.
68. Al-Moagel MA, Evans DG, Abdulghani ME, et al. Prevalence of Helicobacter pylori (formerly Campylobacter) infection in Saudi Arabia, and comparison of those with and without upper gastrointestinal symptoms. Am J Gastroenterol 1990;85:944-8.
69. Graham DY, Malaty HM, Evans EG, Evans DJ Jr, Klein PD, Adam E. Epidemiology of Helicobacter pylori in an asymptomatic population in the United States: effect of age, race, and socioeconomic status. Gastroenterology 1991;100:1495-501.
70. Jones DM, Eldridge J, Fox AJ, et al. Antibody to the gastric Campylobacter-like organism ("Campylobacter pyloridis"). Clinical correlations and distribution in the normal population. J Med Microbiol 1986;22:57-62.
71. Graham DY, Malaty HM, Go MF. Are there susceptible hosts to Helicobacter pylori infection? Scand J Gastroenterol 1994;29(Suppl 205):6-10.
72. Ching CK, Wong BCY, Kwok E, Ong L, Covacc IA, Lam S. Prevalence of CagA-bearing Helicobacter pylori strains detected by the anti-CagA assay in patients with peptic ulcer disease and controls. Am J Gastroenterol 1996;91:949-53.
73. Drossman DA, Thompson WG, Talley NJ, Punch-Jensen P, Janssens J, Whitehead WE. Identification of sub-groups of functional gastrointestinal disorders. Gastroenterol Int 1990;3:159-72.
74. Talley NJ, Weavere AL, Tesmer DL, Zinsmeister AR. Lack of discriminant value of dyspepsia subgroups in patients with referred for upper endoscopy. Gastroenterology 1993;105:1378-86.
75. Mansi C, Savarino V, Mela GS, Piccioto A, Raffaella M, Celle G. Are clinical patterns of dyspepsia a valid guideline for appropriate use of endoscopy? A report on 2253 dyspeptic patients. Am J Gastroenterol 1993;88:1011-5.
76. Hovelius B, Andersson SI, Hagander B, et al. Dyspepsia in general practice: history and symptoms in relation to Helicobacter pylori serum antibodies. Scand J Gastroenterol 1994;29:506-10.
77. Chua A, Kennedy NP, Hamilton D, et al. Dysmotility-type non-ulcer dyspepsia is negatively associated with Campylobacter-like organisms (GCLO). Gut 1988;29:A1437.
78. Kemmer TP, Domínguez-Muñoz JE, Klingel H, Zemmler T, Kuhn K, Malfertheiner P. The association between non-ulcer dyspepsia and Helicobacter pylori infection. Eur J Gastroenterol 1994;6:571-7.
79. Jeena CP, Simjee AE, Pettengell KE, et al. Comparison of symptoms in Campylobacter pylori positive and negative patients presenting with dyspepsia for upper gastrointestinal endoscopy. S Afr Med J 1988;73:A659.
80. Guerre J, Berthe Y, Chaussade S, et al. Has Campylobacter pylori gastritis a specific clinical symptomatology? Klin Wochenschr 1989;67(Suppl 18):A25-6.
81. Goh KL, Parasakthi N, Peh SC, et al. Helicobacter pylori infection and non-ulcer dyspepsia: the effect of treatment with colloidal bismuth subcitrate. Scand J Gastroenterol 1991;26:1123-31.
82. Mearin F, De Ribot X, Balboa A, et al. Does Helicobacter pylori infection increase gastric sensitivity in functional dyspepsia? Gut 1995;37:47-51.
83. Waldron B, Cullen PT, Kumar R, et al. Evidence for hypomotility in non-ulcer dyspepsia: a prospective multifactorial study. Gut 1991;32:246-51.
84. Farum PG, Wetterhus S, Moe B. Impact of Helicobacter pylori infection on symptoms and effect of ranitidine in patients with functional dyspepsia. Gut 1995;37(Suppl 1):A45.
85. Landini MP, Varoli O, Tucci A, et al. Antibodies to Campylobacter pylori in patients with idiopathic dyspepsia. Microbiologica 1989;12:181-8.
86. Barnes RJ, Uff JS, Dent JC, et al. Long term follow up of patients with gastritis associated with Helicobacter pylori infection. Br J Gen Pract 1991;41:286-8.
87. Caballero-Plasencia AM, Muros Navarro MC, Martín-Ruiz JL, et al. Dyspepsia symptoms and gastric emptying of solids in patients with functional dyspepsia. Role of Helicobacter pylori infection. Scand J Gastroenterol 1995;30:745-51.
88. Carballo F, Martínez C, Aldeguer M, et al. Infección por Helicobacter pylori en Guadalajara: prevalencia y factores asociados. Rev Esp Enferm Dig 1995;87(Suppl 1):7.
89. Katelaris PH, Tippett GHK, Norbu P, Lowe DG, Brennan R, Farthing MJG. Dyspepsia, Helicobacter pylori and peptic ulcer in a randomly selected population in India. Gut 1992;33:1462-6.
90. Veldhuyzen van Zanten SJO, Sherman PM. Indications for treatment of Helicobacter pylori infection: a systematic overview. Can Med Assoc J 1994;150:189-98.
91. Parsonnet J, Blaser MJ, Pérez-Pérez GI, et al. Symptoms and risk factors of Helicobacter pylori infection in a cohort of epidemiologist. Gastroenterology 1992;102:41-5.
92. 13C-urea breath test in the detection of Helicobacter pylori and in monitoring the effect of tripotassium dicitrate bismuthate in non-ulcer dyspepsia. Gut 1990;31:1237-41.
93. Tamm A, Villako K, Dyspeptic complains, diet, gastric mucosa and Helicobacter pylori among an Estonian urban population. Scand J Gastroenterol 1991;26(Suppl 186): 100-4.
94. Fich A, Carel RS, Keret D, Goldin E. Seroprevalence of Helicobacter pylori in the Israel population. Eur J Gastroenterol Hepatol 1993;5:339-41.
95. Talley NJ, Piper DW. The association between non-ulcer dyspepsia and other gastrointestinal disorders. Scand J Gastroenterol 1985;20:896-900.
96. Talley NJ. Spectrum of chronic dyspepsia in the presence of the irritable bowel syndrome. Scand J Gastroenterol 1991;26(Suppl 132):7-10.
97. Fink SM, Barwick KW, Deluca V, et al. The association of histologic gastritis with gastroesophageal reflux and delayed gastric emptying. J Clin Gastroenterol 1984;6:301-9.
98. Ihamäki T, Varis K, Siurala M. Morphological, functional and immunological state of the gastric mucosa in gastric carcinoma families: comparison with a computer-matched family sample. Scand J Gastroenterol 1979;14:801-12.
99. Malagelada JR, Stanghellini V. Manometric evaluation of functional upper gut symptoms. Gastroenterology 1985;88:1223-31.
100. Testoni PA, Bagnolo F, Masci E, Colombo D, Tittobello A. Different interdigestive antroduodenal motility patterns in chronic antral gastritis with and without Helicobacter pylori infection. Dig Dis Sci 1993;38:2255-61.
101. Magnall YF, Houghton LA, Johnson AG, Read NW. Abnormal distribution of a fatty test meal within the stomach of patients with non-ulcer dyspepsia. Eur J Gastroenterol Hepatol 1994;6:323-7.
102. Troncon LEA, Bennett RJM, Ahluwalia NK, Thompson DG. Abnormal intragastric distribution of food during gastric emptying in functional dyspepsia patients. Gut 1994;35:327-32.
103. Minocha A, Mokshagundam S, Gallo SH, Rahal PS. Alterations in upper gastrointestinal motility in Helicobacter pylori-positive nonulcer dyspepsia. Am J Gastroenterol 1994;89:1797-1800.
104. Chang CS, Chen GH, Kao CH, Wang SJ, Peng SN, Huang CK. The effect of Helicobacter pylori infection on gastric emptying of digestible and indigestible solids in patients with nonulcer dyspepsia. Am J Gastroenterol 1996;91:474-7.
105. Scott AM, Kellow JE, Shuter B, et al. Intragastric distribution and gastric emptying of solids and liquids in functional dyspepsia. Lack of influence of symptoms subgroups and Helicobacter pylori-associated gastritis. Dig Dis Sci 1993;38:2247-54.
106. Pieramico O, Ditschuneit H, Malfertheiner P. Gastrointestinal motitlity in patients with non-ulcer dyspepsia: a role for Helicobacter pylori infection? Am J Gastroenterol 1993;88:364-8.
107. Qvist N, Rasmussen L, Axelsson CK. Helicobacter pylori-associated gastritis and dyspepsia. The influence on migrating motor complexes. Scand J Gastroenterol 1994;29:133-7.
108. Barnett JL, Behler EM, Happelman HD, Elta GH. Campylobacter pylori is not associated with gastroparesis. Dig Dis Sci 1989;34:1677-80.
109. Marzio L, Falcucci M, Ciccaglione AF, et al. Relationship between gastric and gallbladder emptying and refilling in normal subjects and patients with Helicobacter pylori-positive and negative idiopathic dyspepsia and correlation with symptoms. Dis Dis Sci 1996;41:26-31.
110. Wegener M, Börsch G, Schajjstein J, et al. Are dyspeptic symptoms in patients with Campylobacter pylori-associated type B gastritis linked to delayed gastric emptying? Am J Gastroenterol 1988;83:737-40.
111. Caldwell SH, Valenzuela G, Marshall BJ, et al. Helicobacter pylori infection and gastric emptying of solids in humans. J Gastrointest Mot 1992;4:113-7.
112. Perri F, Ghoos YVOF, Maes BD, et al. Gastric emptying and Helicobacter pylori infection in duodenal ulcer disease. Dig Dis Sci 1996;41:462-8.
113. Monés Xil J, Sáinz Sáenz-Torre S, Carrio Gasset I, Berna Roqueta L, Sancho Poch FJ, Vilardell Viñas F. Dispepsia funcional, vaciado gástrico de sólides e infección por Helicobacter pylori. Rev Esp Enferm Dig 1994;85:325-30.
114. Murakami K, Fukioka T, Shiota K, et al. Influence of Helicobacter pylori infection and the effects of its eradication on gastric emptying in non-ulcerative dyspepsia. Eur J Gastroenterol Hepatol 1995;7:993-7.
115. Testoni PA, Bagnolo F, Colombo E, Bonassi U, Tosi T. The correlation in dyspeptic patients of Helicobacter pylori infection with changes in interdigestive gastroduodenal motility patterns but not in gastric emptying. Helicobacter 1996;1:229-37.
116. Pieramico O, Baczako K, Malfertheiner P. Gastroduodenal motility in relation to inflammatory and fibrotic changes of antral mucosa. Ital J Gastroenterol 1991;23(Suppl 2):9-12
117. Holtmann G, Talley N, Goebell H, Association between H. pylori, duodenal mechanosensory thresholds, and small intestinal motility in chronic unexplained dysplasia. Dig Dis Sci 1996;41:1285-91.
118. Su YC, Jan CM, Wang WM, et al. Does Helicobacter pylori infection play a role in the pathogenesis of non-ulcer dyspepsia? A study emptying time. Kao Hsiung I Hsueh Ko Hsueh Tsa Chih 1995;11:8-14.
119. Peitz U, Blaudszun S, Tillenburg B, et al. Delayed gastric emptying unchanged after cure of H. pylori infection in functional dyspepsia. Gut 1996;39(Suppl 2):A23.
120. Gisbert JP, Boixeda D, Vila T, De Rafael L, Álvarez Baleriola I, Martín de Argila C. Decrease of basal and stimulated gastrin levels: a useful non-invasive method for checking Helicobacter pylori eradication after therapy. Gastroenterol Int 1995;8:8-16.
121. Gisbert JP, Boixeda D, Vila T, et al. Verification of decreased basal and stimulated serum pepsinogen I levels is a useful non-invasive method for determining the success of eradication therapy on Helicobacter pylori. Scand J Gastroenterol 1996;31:103-110.
122. Oderda G, Vaira D, Holton J, et al. Amoxycillin plus tinidazole for Campylobacter pylori gastritis in children: assessment by serum IgG antibody, pepsinogen I, and gastrin levels. Lancet 1989;1:690-2.
123. Oderda G, Vaira D, Dell'Olio D, et al. Serum pepsinogen I and gastrin concentrations in children positive for Helicobacter pylori. J Clin Pathol 1990;43:762-5.
124. Biasco G, Paganelli GM, Vaira D, et al. Serum pepsinogen I and II concentrations and IgG antibody to Helicobacter pylori in dyspeptic patients. J Clin Pathol 1993;46:826-8.
125. Hunter FM, Correa P, Fontham E, Ruiz B, Sobhan M, Samloff IM. Serum pepsinogens as markers of response to therapy for Helicobacter pylori gastritis. Dig Dis Sci 1993;38:2081-6.
126. El-Omar E, Penman I, Ardill JES, McColl KEL. A substantial proportion of non-ulcer dyspepsia patients have the same abnormality of acid secretion as duodenal ulcer patients. Gut 1995;36:534-8.
127. Gisbert JP, Boixeda D, Vila T, et al. Infección por Helicobacter pylori y concentraciones basales de gastrina sérica en pacientes ulcerosos duodenales y con endoscopia normal. Med Clin (Barc) 1996;106:325-8.
128. Gisbert JP, Boixeda D, Vila T, De Rafael L, Redondo C, Martin de Argila C. Basal and stimulated gastrin levels and gastric acid output 5 months after therapy for Helicobacter pylori eradication in duodenal ulcer patients. J Clin Gastroenterol 1996;22:90-5.
129. Collen MJ, Loebenberg MJ. Basal gastric acid secretion in nonulcer dyspepsia with or without duodenitis. Dig Dis Sci 1989;34:246-55.
130. O'Morain C, Buckley M. Helicobacter pylori and dyspepsia. Scand J Gastroenterol 1996;31(Suppl 214):28-30.
131. McColl KEL, Fullarton GM. Duodenal ulcer pain: the role of acid and inflammation. Gut 1993,34:1300-3.
132. George A, Tsuchiyose M, Dooley CP. Sensitivity of the gastric mucosa to acid and duodenal contents in patients with non-ulcer dyspepsia. Gastroenterology 1991;101:3-6.
133. Frommer DJ, Carrick J, Lee A, et al. Acute presentation of Campylobacter pylori gastritis. Am J Gastroenterol 1988;83:1168-71.
134. Graham DY, Alpert LC, Smith JL. Iatrogenic Campylobacter pylori infection as a cause of epidemic achlorhydria. Am J Gastroenterol 1988;83:974-80.
135. Marshall BJ, Armstrong JA, McGechie DB, et al. Attempt to fulfill Koch's postulates for Pyloric Campylobacter. Med J Aust 1985;142:436-9.
136. Morris A, Nicholson G. Ingestion of Campylobacter pyloridis causes gastritis and raised fasting gastric pH. Am J Gastroenterol 1987;82:192-9.
137. Ransey EJ, Carey KV, Peterson WL, et al. Epidemic gastritis with hypochlorhydria. Gastroenterology 1979;76:1449-57.
138. Sobala GM, Crabtree JE, Dixon MF, et al. Acute Helicobacter pylori infection: clinical features, local and systemic immune response, gastric mucosal histology, and gastric juice ascorbic acid concentrations. Gut 1991;32:1415-8.
139. Morris A, Ali MR, Nicholson G, Pérez-Pérez GI, Blaser MJ. Long-term follow up of voluntary ingestion of Helicobacter pylori. Ann Intern Med 1991;114:662-3.
140. Sipponen P, Varis K, Fraki O, et al. Cumulative 10 yr risk of symptomatic duodenal and gastric ulcer in patients with or without chronic gastritis. Scand J Gastroenterol 1990;25:966-73.
141. Dooley CP, Cohen H, Fitzgibbons PL. Prevalence of Helicobacter pylori infection and histologic gastritis in asymptomatic persons. N Engl J Med 1989;321:1562-5.
142. Cullen DJE, Collins J, Christiansen KJ, Epis J, Warren JR, Cullen KJ. Long term risk of peptic ulcer disease in people with Helicobacter pylori infection - A community based study. Gastroenterology 1993;104(Suppl 2):A60.
143. Nomura A, Stemmermann GN, Chyou P, et al. Helicobacter pylori infection and the risk for duodenal ulcer and gastric ulceration. Ann Intern Med 1994;120:977-81.
144. Kuipers EJ, Thijs JC, Festen HPM. The prevalence of Helicobacter pylori in peptic ulcer disease. Aliment Pharmacol Ther 1995;9(Suppl 2):59-69.
145. McNulty CAM, Gearty JC, Crump B. Campylobacter pylori and associated gastritis: investigator blind placebo-controlled trial of bismuth salicylate and erythromycin ethylsuccinate. Br Med J 1986;293:645-9.
146. Borody T, Hennessy W, Daskalopoulos G, et al. Double-blind trials of De-No1 in non-ulcer dyspepsia associated with Campylobacter pyloridis gastritis. Gastroenterology 1987,92:A1324.
147. Gilman R, León-Barua R, Ramírez-Ramos A, et al. Efficacy of nirrofurans in the treatment of antral gastritis with Campylobacter pyloridis. Gastroenterology 1987;92:1405-8.
148. Morgan D, Draft W, Bender M, et al. Nitrofurans in the treatment of gastritis associated with Campylobacter pylori. Gastroenterology 1988;95:1178-84.
149. Rokkas T, Pursey C, Uzoechina E, et al. Non-ulcer dyspepsia and short-term De-No1 therapy: a placebo controlled trial with particular reference to the role of Campylobacter pylori. Gut 1988;29:1386-91.
150. Loffeld RJLF, Potters HVJP, Stobberingh E, et al. Campylobacter associated gastritis in patients with non-ulcer dyspepsia: a double blind placebo-controlled trial with colloidal bismuth subcitrate. Gut 1989;30:1206-12.
151. Kang JY, Tay HH, Wee A. Effect of colloidal bismuth subcitrate on symptoms and gastric histology in non-ulcer dyspepsia: a double blind placebo controlled study. Gut 1990;31:476-80.
152. Glupczynski Y, Burette A, Labbe M. Campylobacter pylori associated gastritis: a double-blind placebo-controlled trial with amoxicillin. Am J Gastroenterol 1988;83:365-72.
153. Gastrointestinal Physiology Working Group of Cayetano Heredia and the Johns Hopkins Universities et al. Nitrofurans in the treatment of gastritis associated with Campylobacter pylori. Gastroenterology 1988;95:1178-84.
154. Vaira D, Holton J, Ainley C, et al. Double blind trial of colloidal bismuth subcitrate versus placebo in Helicobacter pylori positive patients with non-ulcer dyspepsia. Ital J Gastroenterol 1992;24:400-4.
155. Kazy JI, Jafarey NA, Alam SM, et al. A placebo controlled trial of bismuth salicylate in Helicobacter pylori associated gastritis. JAMA 1990;40:154-6.
156. Patchett S, Beattie S, Leen E, Keane C, O'Morain C. Eradicating Helicobacter pylori and symptoms of non-ulcer dyspepsia. Br Med J 1991;303:1238-40.
157. Marshall BJ, Valenzuela JE, McCallum RW, et al. Bismuth subcalicylate suppression of Helicobacter pylori in nonulcer dyspepsia: a double-blind placebo-controlled trial. Dig Dis Sci 1993;38:1674-80.
158. Westblom TU, Maden E, Subik MA, Duriex DE, Midkiff BR. Double-blind randomized trial of bismuth subsalicylate and clindamycin for treatment of Helicobacter pylori infection. Scand J Gastroenterol 1992;27:249-52.
159. Holcombe C, Thom C, Kaluba J, Lucas SB. Helicobacter pylori clearance in the treatment of non-ulcer dyspepsia. Aliment Pharmacol Ther 1992;6:119-23.
160. Nafeeza MI, Shahimi MM, Kudva MV, et al. Evaluation of therapies in the treatment of Helicobacter pylori associated non-ulcer dyspepsia. Singapore Med J 1992;33:570-4.
161. Gormally SM, Prakash N, Durnin M, Daly L, Kierce B, Drumm B. Symptoms in children before and after treatment of Helicobacter pylori infection. Gastroenterology 1994;106:A83.
162. Frazzoni M, Lonardo A, Grisendi A, et al. Are routine duodenal and antral biopsies useful in the management of "functional" dyspepsia? A diagnostic and therapeutic study. J Clin Gastroenterol 1993;17:101-8.
163. Valdhuyzen van Zanten SJO, Malatjalian D, et al. The effect of eradication of Helicobacter pylori on symptoms on nonulcer dyspepsia: a randomized double-blind placebo controlled trial. Gut 1995;37(Suppl 1):A56.
164. McCarthy C, Patchett S, Collind RM, et al. Long-term prospective study of Helicobacter pylori in non ulcer dyspepsia. Dig Dis Sci 1995;40:114-9.
165. Sheu BS, Lin CY, Lin XZ, Shiesh SC, Yang HB, Chen CY. Long-term outcome of triple therapy in Helicobacter pylori-related dyspepsia: a prospective controlled assessment. Am J Gastroenterol 1996;91:441-7.
166. Lazzaroni M, Bargiggia A, Sangaletti O, Maconi G, Boldorini M, Bianchi Porro G. Eradication of Helicobacter pylori and long-term outcome of functional dyspepsia. A clinical endoscopic study. Dis Dis Sci 1996;41:1589-94.
167. Greenberg PD, Cello JP. Prospective, double-blind treatment of Helicobacter pylori in patients with non-ulcer dyspepsia. Gastroenterology 1996;110:A310.
168. Ozmen MM, Patanker RS, Johnson CD. The effect of Helicobacter pylori eradication on symptoms relief in patients with functional dyspepsia. Gastroenterology 1995;108:A997.
169. El-Omar E, Wirz A, McColl KEL. Effect of Helicobacter pylori eradication on the severity of dyspeptic symptoms in duodenal ulcer patients. Gastroenterology 1995;108:A88.
170. Catalano F, Terranova R, Brojna A, et al. Helicobacter pylori positive functional dyspepsia in elderly patients: comparison of two treatments. Gastroenterology 1995;108:A67.
171. Van Zanten SV, Malatjalian D, Tanton R, et al. The effect of eradication of Helicobacter pylori on symptoms on non-ulcer dyspepsia. Gastroenterology 1995;108:A250.
172. Talley NJ. A critique of therapeutic trials in Helicobacter pylori positive functional dyspepsia. Gastroenterology 1994;106:1174-83.
173. Maillot C, Ducrotè P. Chronic idiopathic dyspepsia. Gastroenterol Int 1996;9:16-27.
174. Konturek SJ, Radecki T, Piastucki I, Drozkowicz D. Advances in the understanding of the mechanism of cytoprotective action by colloidal bismuth subcitrate. Scand J Gastroenterol 1986;22(Suppl):6-10.
175. Ching CK, Lam SK. Nonulcer dyspepsia: association with chronic Helicobacter pylori infection-related gastritis? Scand J Gastroenterol 1995;21(Suppl 1):S140-5.
176. Talley NJ, Phillips SF, Melton LJ III, et al. A patient questionnaire to identify bowel disease. Ann Intern Med 1989;111:671-4.
177. Veldhuyzen van Zanten SJO, Cleary C, Talley NJ, et al. Drug treatment of functional dyspepsia: a systematic analysis of trial methodology with recommendations for design of future trials. Am J Gastroenterol 1996;91:660-71.
178. Freiman JA, Chalmers TC, Smith H, Duebler RR. The importance of veta, the type II error and sample size in the design and interpretation of the randomized controlled trial: survey of 71 ''negative" trials. N Engl J Med 1978;299:690-4.
179. Valle J, Seppala K, Sipponen P. Disappearance of gastritis after eradication of Helicobacter pylori: a morphometric study. Scand J Gastroenterol 1991;26:1057-62.
180. Gilvarry J, Buckley M, Beattie S, et al. Eradication of Helicobacter pylori affects symptoms in non-ulcer dyspepsia. Acta Gastroenterol Belg 1993;56:49.
181. Oddsson E, Gudjonsson H, Theodore A, et al. DeNo1 or DeNo1 + metronidazole in the treatment of Helicobacter pylori-positive patients with nonulcer dyspepsia: symptomatic response and eradication rate. Scand J Gastroenterol 1992;27(Suppl 190):42.
182. Petrino R, DiNapoli A, Boero M, Belis D, Bottino P, Chiandussi L. Cure of chronic dyspepsia with eradication of Helicobacter pylori. Ital J Gastroenterol 1991;23(Suppl 2):213.
183. Petrolani S, Bonvicini F, Brocchi E, et al. Non-ulcer dyspepsia: is there any correlaton between clinical symptoms and histopathological features? Ital J Gastroenterol 1991;23(Suppl 2):80.
184. Marshall BJ. Should we now, routinely, be examining gastric biopsies for Campylobacter pylori? Gastric mucosal biopsi: an essential investigation in patients with dyspepsia. Am J Gastroenterol 1988;83:479-81.
185. McQuaid KR. Endoscopy-negative dyspepsia. Hold those forcepsl. J Clin Gastroenterol 1993;17:97-100.
186. Marshall BJ. Managing acid peptic disease in the Helicobacter pylori era. J Clin Gastroenterol 1995;21(Suppl 1) S155-S9.
187. Graham DY. Patients, payers, and paradigm shifts: what to do about Helicobacterpylori. Am J Gastroenterol 1996;91:188-90.
188. Fendrick AM, Chernew ME, Hirth RA, Bloom BS. Alternative management strategies for patients with suspected peptic ulcer disease. Ann Intern Med 1995;123:260-8.
189. 13C-UBT): comparison with and impact on open access endoscopy. Gut 1996;38(Suppl 1):A34.
190. Reilly TG, Stone D, Poxon V, Elliott TSJ, Walt RP. Helicobacter pylori serology in the investigation of dyspepsia: a general practice based follow-up study. Gut 1996;38(Suppl 1):A65.
191. Cammilleri M. Nonulcer dyspepsia: a look into the future. Mayo Clin Proc 1996;71:614-22.
192. Malfertheiner P, Mégraud F, O'Morain C, et al. Current European concepts in the management of Helicobacter pylori infection - the Maastricht Consensus Report. Eur J Gastroenterol Hepatol 1997;9:1-2.
193. Briggs AH, Sculpher MJ, Logan RPF, Aldous J, Ramsay ME, Baron JH. Cost effectiveness of screening for and eradication of Helicobacter pylori in management of dyspeptic patients under 45 years of age. Br Med J 1996;312:1321-5.
194. Tham TC, McLaughlin N, Hughes DF, et al. Possible role of Helicobacter pylori serology in reducing endoscopy workload. Postgrad Med J 1994;70:809-12.
195. Mendall MA, Jazrawi RP, Marrero JM, et al. Serology for Helicobacter pylori compared with symptom questionnaires in screening before direct access endoscopy. Gut 1995;36:330-3.
196. Sobala GM, Crabtree JE, Pentith JA, et al. Screening dyspepsia by serology to Helicobacter pylori. Lancet 1991;338:94-6.
197. Hawtin PR, Sharpstone D, Treasure J, Fine D, Newell DG. The value of serodiagnosis of Helicobacter pylori in prediction negative gastroscopy. Ital J Gastroenterol 1991;23:23.
198. Patel P, Khulusi S, Mendall MA, et al. Prospective screening of dyspeptic patients by Helicobacter pylori serology. Lancet 1995;346:1315-8.
199. Collins JSA, Bamford KB, Collins BJ, Sloan JM, Moorehead RJ, Love AHG. Predictive values of Helicobacter pylori serology versus endoscopy in young dyspeptic patients. Rev Esp Enferm Dig 1990;78:34-5.
200. Meyer B, Werth B, Beglinger C, et al. Screening for Helicobacter pylori in dyspepsia. Lancet 1991;338:393-4.
201. Valdhuyzen van Zanten SJO, Sherman PM. Helicobacter pylori infection as a cause of gastritis, duodenal ulcer, gastric cancer and nonulcer dyspepsia: a systematic overview. Can Med Assoc J 1994;150:177-85.
202. Walsh J. Helicobacter pylori: selection of patients for treatment. Ann Intern Med 1992;116:770-1.
203. Talley NJ. A relationship between Helicobacter pylori and non-ulcer dyspepsia: is there enough data to know? Eur J Gastroenterol Hepatol 1994;6:567-70.
204. Thijs JC, Kuipers EJ, Van Zwet AA, Pena AS, De Graaff JK. Treatment of Helicobacter pylori infections. Q J Med 1995;88:369-89.
205. NIH Consensus Conference. Helicobacter pylori in peptic ulcer disease. JAMA 1994;272:65-9.
206. Hill AB. The environment and disease: association or causation. Proc R Soc Med 1965;58:295-9.
207. Gisbert JP, Boixeda D, Martín de Argila C, García Plaza A. Helicobacter pylori y úlcera duodenal. ?Relación causal o mera asociación? Rev Clin Esp 1997;197:693-702.
208. Nyren O, Adami H, Gustavsson S, et al. Social and economic effects of non-ulcer dyspepsia. Scand J Gastroenterol 1985;209(Suppl 109):41-7.
209. Talley NJ, Weaver AL, Zinsmeister AR. Impact of functional dyspepsia on quality of live. Dis Dis Sci 1995;40:584-9.
210. Powell KU, Bell GD, Bowden AF, Brandon M, Jones PH. Preliminary report on the financial implications of treating patients with non ulcer dyspepsia with eradication therapy for Helicobacter pylori. Gut 1996;39(Suppl 2):A23.