Transdermal iontophoretic delivery of hydrocortisone from cyclodextrin solutions

Journal of Pharmacy and Pharmacology

Volumn 50, Issue 6, 1998, Pages 635-640

  Chang, Shu Lun ^a   Banga, Ajay K ^a  

^a AUBURN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLODEXTRIN; GLUCOCORTICOID; HYDROCORTISONE; OLEIC ACID; PROPYLENE GLYCOL; SOLVENT;

AQUEOUS SOLUTION; ARTICLE; CADAVER; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; HUMAN; HUMAN TISSUE; IONTOPHORESIS; SKIN PENETRATION; SOLUBILIZATION; TRANSDERMAL DRUG ADMINISTRATION;

EID: 0031861137     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.1998.tb06897.x     Document Type: Article

References (15)

1. Arima, H., Adachi, H., Irie, T., Uekama, K. (1990) Improved drug delivery through the skin by hydrophilic β-cyclodextrins: enhancement of the anti-inflammatory effect of 4-biphenylacetic acid in rats. Drug Invest. 2: 155-161
2. Banga, A. K., Chien, Y. W. (1988) Iontophoretic delivery of drugs: fundamentals, developments and biomedical applications. J. Contr. Rel. 7: 1-24
3. Fuhrman, L. C., Michniak, B. B., Behl, C. R., Malick, A. W. (1997) Effect of novel penetration enhancers on the transdermal delivery of hydrocortisone: an in vitro species comparison. J. Contr. Rel. 45: 199-206
4. Lin, R. Y., Ou, Y. C., Chen, W. Y. (1997) The role of electroosmotic flow on in vitro transdermal iontophoresis. J. Contr. Rel. 43: 23-33
5. Loftsson, T., Siguroardottir, A. M. (1994) The effect of polyvinylpyrrolidone and hydroxypropyl methylcellulose on HP beta CD complexation of hydrocortisone and its permeability through hairless mouse skin. Eur. J. Pharm. Sci. 2: 297-301
6. Loftsson, T., Frioriksdottir, H., Ingvarsdottir, G., Jonsdottir, B., Siguroardottir, A. M. (1994) The influence of 2-hydroxypropyl-beta-cyclodextrin on diffusion rates and transdermal delivery of hydrocortisone. Drug Dev. Ind. Pharm. 20: 1699-1708
7. Michniak, B. B., Player, M. R., Chapman, J. M., Sowell, J. W. (1994) Azone analogues as penetration enhancers: effect of different vehicles on hydrocortisone acetate skin permeation and retention. J. Contr. Rel. 32: 147-154
8. Pikal, M. J. (1992) The role of electroosmotic flow in transdermal iontophoresis. Adv. Drug Del. Rev. 9: 201-237
9. Preiss, A., Mehnert, W., Fromming, K. H. (1994) Complexation of hydrocortisone with beta-cyclodextrin and hydroxypropyl-beta-cyclodextrin. Arch. Pharm. 327: 729-734
10. Preiss, A., Mehnert, W., Fromming, K. H. (1995) Penetration of hydrocortisone into excised human skin under the influence of cyclodextrins. Pharmazie 50: 121-126
11. Seth, S. C., Allen, L. V., Pinnamaraju, P. (1994) Stability of hydrocortisone salts during iontophoresis. Int. J. Pharm. 106: 7-14
12. Szejtli, J. (1994) Medicinal applications of cyclodextrins. Med. Res. Rev. 14: 353-386
13. Tauber, U. (1994) Dermatocorticosteroids: structure, activity, pharmacokinetics. Eur. J. Dermatol. 4: 419-429
14. Vollmer, U., Muller, B. W., Peeters, J., Mesens, J., Wilffert, B., Peters, T. (1994) A study of the percutaneous absorption-enhancing effects of cyclodextrin derivatives in rats. J. Pharm. Pharmacol. 46: 19-22
15. Wang, Y., Allen, L. V., Li, L. C., Tu, Y. H. (1993) Iontophoresis of hydrocortisone across hairless mouse skin: investigation of skin alteration. J. Pharm. Sci. 82: 1140-1144